Keywords: رین; Constant absorbance pattern; Diacerein; Rhein; Validation;
مقالات ISI رین (ترجمه نشده)
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Keywords: رین; Combination chemotherapy; Rhein; Doxorubicin; Micelles; Multidrug resistance;
Keywords: رین; Methotrexate; Diacerein; Rhein; Hepatotoxicity; Nuclear factor erythroid 2-related factor 2;
Keywords: رین; UPLC; ultra-performance liquid chromatography; A; aloe-emodin; R; rhein; E; emodin; CP; chrysophanol; PS; physcion; AG; aloe-emodin-8-O-β-D-glucopyranoside; EG; emodin-8-O-β-D-glucopyranoside; RG; rhein-8-O-glucopyranoside; DMSO; dimethyl sulfoxide; CE;
Keywords: رین; Rhein; Rhein acyl glucuronide; Methotrexate; Organic anion transporter; Drug-drug interaction; AUC; area under the plasma time-concentration curve; ES; estrone sulfate; HBSS; Hank's balanced salt solution; HEK293; human embryonic kidney 293; IS; internal
Keywords: رین; Osteoarthritis; Rhein; Microparticles; Cytotoxic assays; Anti-inflammatory; Controlled release; Rhein (PubChem CID: 10168);
Keywords: رین; Metabolomics; Pharmacokinetic; Pharmacodynamic; Rhein; Rhubarb; UPLC-QTOF/MS; Ultra performance liquid chromatography - micromass quadrupole - time of flight mass spectrometry; UPLC-MS/MS; Ultra performance liquid chromatography - triple quadrupole tandem
Keywords: رین; AP; acute pancreatitis; HMPDM; N,N,Nâ²-trimethyl-Nâ²-(2-hydroxyl-3-methyl)-1,3-propanediamine; HPDM; N,N,Nâ²-trimethyl-Nâ²-(4-hydroxy-3-methyl-benzyl)-1,3-propane diamine; HPDM-Rhein; HPDM-Rhein conjugate; DTI; drug targeting efficiency index; OTC
Keywords: رین; Rhein; Chrysophanol; QYQRG; Pharmacokinetics; Blood stasis syndrome;
Keywords: رین; Traditional Chinese medicine; Rhein; Loperamide-induced constipation; Microarray; Pharmacokinetics;
Keywords: رین; Rhein; β-Cyclodextrin; Conjugate; Biological activity
Rhein augments ATRA-induced differentiation of acute promyelocytic leukemia cells
Keywords: رین; Rhein; Acute promyeloid leukemia; All-trans retinoic acid; Differentiation; Cytotoxicity; Anti-leukemic activity; APL; acute promyelocytic leukemia; AML; acute myeloid leukemia; ATRA; all-trans retinoic acid; PML; promyelocytic leukemia; RARα; retinoic a
In vitro and in vivo metabolic activation of rhein and characterization of glutathione conjugates derived from rhein
Keywords: رین; CE; collision energy; DMSO; dimethyl sulfoxide; DP; declustering potential; RH; rhein; EPI; enhanced product ion; GSH; glutathione; IDA; information-dependent acquisition; LC-MS/MS; liquid chromatography-tandem mass spectrometry; MRM; multiple-reaction mo
Rhein ameliorates adenomyosis by inhibiting NF-κB and β-Catenin signaling pathway
Keywords: رین; rhein; NF-κB; β-catenin; IL-1β; adenomyosis;
Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma
Keywords: رین; Nasopharyngeal carcinoma; Rhein; Inverse docking; Multi-target radiotherapy sensitization agent; Biological evaluation;
Bioassay-guided fractionation and antimicrobial and cytotoxic activities of Cassia bakeriana extracts
Keywords: رین; Antimicrobial activity; Cassia bakeriana; Cassic acid; Cytotoxicity; 1,8-Dihydroxy-anthraquinone-3-carboxylic acid; Rhein;
Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease
Keywords: رین; CKD; DNA methylation; epigenetics; Klotho; rhein;
Design, synthesis, and characterization of rhein analogs as novel inhibitors of scavenger receptor A
Keywords: رین; Scavenger receptor A; Rhein; Danthron; Cancer immunotherapy;
Rhein induces apoptosis and autophagy in human and rat glioma cells and mediates cell differentiation by ERK inhibition
Keywords: رین; Glioma; Rhein; GFAP; ERK pathway;
Rhein triggers apoptosis via induction of endoplasmic reticulum stress, caspase-4 and intracellular calcium in primary human hepatic HL-7702 cells
Keywords: رین; Rhein; Apoptosis; Caspase-4; Calcium; HL-7702 cells
Immunomodulatory potential of Rhein, an anthraquinone moiety of Cassia occidentalis seeds
Keywords: رین; Rhein; Splenocytes; Immunomodulation; Cytokines; Lymphoproliferation; Surface receptorsAPC, allophycocyanin; APC-Cy7, allophycocyanin-cyanine 7; CD, clusters of differentiation; Con A, concanvalin A; DMEM, Dulbecco's Modified Eagles Medium; FITC, fluoresc
In vitro anti-Neisseria gonorrhoeae activity of Senna podocarpa root extracts
Keywords: رین; Spr; Senna podocarpa root hydro-ethanol extract; Spr-1; diethyl ether liquid-liquid fraction of S. podocarpa root extract; Spr-2; ethyl acetate liquid-liquid fraction of S. podocarpa root extract; Spr-3; water liquid-liquid fraction of S. podocarpa
The anthraquinone rhein exhibits synergistic antibacterial activity in association with metronidazole or natural compounds and attenuates virulence gene expression in Porphyromonas gingivalis
Keywords: رین; Anthraquinone; Periodontitis; Porphyromonas gingivalis; Rhein; Synergy
Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studies
Keywords: رین; Scavenger receptor A; Natural product; Rhein; Cysteine-rich domain; Homology model; Cancer therapy;
Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates
Keywords: رین; Rhein; α-Aminophosphonates; Synthesis; Cytotoxicity; Apoptosis; DNA binding;
Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages
Keywords: رین; AP-1; activator protein-1; HMGB1; high-mobility-group box 1; IKK; IκB kinase; iNOS; inducible nitric oxide synthase; IL-1β; interleukin-1β; IL-6; interleukin-6; LPS; lipopolysaccharide; NF-κB; nuclear factor-κB; O2â; superoxide anion; OA; osteoarth
Comparative pharmacokinetics study of three anthraquinones in rat plasma after oral administration of Radix et Rhei Rhizoma extract and Dahuang Fuzi Tang by high performance liquid chromatography-mass spectrometry
Keywords: رین; Pharmacokinetics; Rhein; Aloe-emodin; Emodin;
Potential role of ATP-binding cassette transporters in the intestinal transport of rhein
Keywords: رین; ABC; ATP-binding cassettet; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP2; multidrug resistance-associated protein 2; B; basolateral; A; apical; MDCKII; Mardin-Darby canine kidney II; Rhein; ATP-binding cassette transporters; Rat in
Reduced system exposures of total rhein and baicalin after combinatory oral administration of rhein, baicalin and berberine to beagle dogs and rats
Keywords: رین; Rh; rhein; BG; baicalin; B; baicalein; Be; berberine; SHXXT; San-Huang-Xie-Xin-Tang; HLJDT; Huang-Lian-Jie-Du-Tang; PSP; phenolsulfonphthalein; HPLC; High performance liquid chromatography; Papp; apparent permeability coefficient; Rhein; Baicalin; Berberi
Studies on a rhein-producing endophytic fungus isolated from Rheum palmatum L.
Keywords: رین; Medicinal plant; Rheum palmatum L.; Endophytic fungi; Anthraquinones; Rhein
Pharmacokinetic behavior of argirein, derived from rhein, is characterized as slow release and prolonged T1/2 of rhein in rats
Keywords: رین; Argirein; Rhein; Pharmacokinetic; Bioavailability; HPLC; Rat
Standardization and toxicity evaluation of Cassia fistula pod pulp extract for alternative source of herbal laxative drug
Keywords: رین; anthraquinone; Cassia fistula; laxative; rhein; standardization;
Quantitative determination of rhein in human plasma by liquid chromatography–negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study
Keywords: رین; Pharmacokinetics; Rhein; Human plasma; LC–MS/MS
Bone-targeting glycol and NSAIDS ester prodrugs of rhein: Synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies
Keywords: رین; Rhein; NSAIDs; Bone-targeting; Anti-inflammatory; Ulcerogenic; Pharmacokinetics
Antifeedant and larvicidal activities of Rhein isolated from the flowers of Cassia fistula L.
Keywords: رین; Antifeedant; Larvicidal; Cassia fistula; Rhein; Spodoptera litura; Helicoverpa armigera
Rhein protects against acetaminophen-induced hepatic and renal toxicity
Keywords: رین; Rhein; Toxicity; Acetaminophen; Liver and kidney injuries;
Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei
Keywords: رین; Anthraquinone; Rhein; Anti-angiogenesis; Zebrafish; HUVECs; Angpt2; Tie2
Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro
Keywords: رین; Rhein; Natural products; Anthraquinones; Non-invasive breast cancer; Invasive breast cancer; Hypoxia tumor angiogenesis
Simultaneous HPLC–UV determination of rhein and aceclofenac in human plasma
Keywords: رین; Rhein; Aceclofenac; Human plasma; Quantification; Reversed-phase chromatography; Pharmacokinetics
Anti-angiogenic effects of rhubarb and its anthraquinone derivatives
Keywords: رین; Rhubarb; Rheum; Anti-angiogenesis; Zebrafish; Anthraquinone; Rhein
Solubility, spectroscopic properties and photostability of Rhein/cyclodextrin inclusion complex
Keywords: رین; Rhein; Cyclodextrins; Phase-solubility studies; Fluorescence; Visible spectroscopy; Photostability
Rhein inhibits invasion and migration of human nasopharyngeal carcinoma cells in vitro by down-regulation of matrix metalloproteinases-9 and vascular endothelial growth factor
Keywords: رین; Rhein; Nasopharyngeal carcinoma cells; MMP-9; VEGF; GRB2/SOS-Ras-MAPK; NF-κB
Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology
Keywords: رین; CpG DNA; Sepsis; Affinity biosensor; Traditional Chinese herbs; RadixetRhizomaRhei; Rhein
Global transcriptional response of Staphylococcus aureus to Rhein, a Natural Plant Product
Keywords: رین; Staphylococcus aureus; Rhein; GeneChip; Transcription
Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice
Keywords: رین; Cytokines; Diacerhein; Rhein; Autoimmune diabetes
Study on the electrochemical behavior and differential pulse voltammetric determination of rhein using a nanoparticle composite film-modified electrode
Keywords: رین; Rhein; Electrocatalysis; Differential pulse voltammetry; Nanoparticle composite film-modified electrode
Interaction of rhein with human serum albumin investigation by optical spectroscopic technique and modeling studies
Keywords: رین; Human serum albumin (HSA); Rhein; Circular dichroism (CD); Fourier transformation infrared spectra (FT-IR); Fluorescence quenching; Fluorescence anisotropy
Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography
Keywords: رین; HPLC; Plasma; Column-switching; Traditional Chinese medicine; Baicalin; Rhein; Berberine
A validated HPLC stability-indicating method for the determination of diacerhein in bulk drug substance
Keywords: رین; Diacerhein; Rhein; Aloe-emodin; HPLC; Stability-indicating; Quality control;
Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins
Keywords: رین; Emodin; Rhein; Aloe-emodin; Aloin; Serum albumin; Flurorescence quenching;