دانلود مقالات ISI درباره ریکتور + ترجمه فارسی

ترانسکتنمیک های متقابل و پروتئومیکای غنی سازی محیط زیست و کوکائین استراتژی های جدید درمان برای اعتیاد را مشخص می کند

Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction

Keywords: ریکتور; APP; amyloid precursor protein; ATF; activating transcription factor 6; CREB; cAMP response element binding protein; EC; enriched condition; EDTA; ethylenediaminetetraacetic acid; ERK; extracellular signal regulated kinase; FR1; fixed ratio 1; GO; Gene On

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

سیگنالینگ مضر در سرطان

Contextual signaling in cancer

Keywords: ریکتور; AKT; protein kinase B; ATF4; activating transcription factor 4; cAMP; cyclic adenosine monophosphate; CCL5; (C-C motif) ligand 5; CNS; central nervous system; 4EBP1; 4E (elF4E) binding protein; ECM; extracellular matrix; ERK; p44/p42 extracellular signal-

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

(فعالیت mTORC2 Basal) و بیان اجزای آن، تغییرات روزانه در بافت چربی پریمواسکولی موش را نشان می دهد

Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue

Keywords: ریکتور; mTORC2; Rictor; Diurnal; mSIN1; PKCalphamTOR, mammalian target of rapamycin; mTORC2, mTOR complex 2; ZT, zeitgeber time; PKC, protein kinase C; TNFα, tumor necrosis factor α; NOS2, inducible nitric oxide synthase 2; PVAT, perivascular adipose tissue; BAT,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

mTORC2 و AMPK از طریق پریلایپین 3، محتوای تری گلیسیرید عضله را به طور متفاوتی تنظیم می کنند

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

Keywords: ریکتور; PLIN3; RICTOR; mTOR; Metabolism; Akt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The mechanisms and clinical significance of PDCD4 in colorectal cancer

Keywords: ریکتور; Abbreviations; Full name in English; 3′-UTR; 3′-untranslated region; AA; asiatic acid; AOM; azoxymethane; AP-1; activating protein 1; AR; aldose reductase; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; CAC; colitis-associated CRC; CD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2019 سفارش ترجمه

eIF4E Phosphorylation in Prostate Cancer

Keywords: ریکتور; eIF4E; eukaryotic translation initiation factor 4E; mTOR; mammalian target of rapamycin; PCa; prostate cancer; Mnk; mitogen activated protein kinase interacting protein kinase; ADT; androgen deprivation therapy; MAPK; mitogen-activated protein kinase; CRP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

In situ analysis of mTORC1/2 and cellular metabolism-related proteins in human Lymphangioleiomyomatosis

Keywords: ریکتور; ACSS2; acyl-coenzyme A synthetase short-chain family member 2; ATPB; β-F1-ATPase; BSM; bronchial smooth muscle; CPT1A; carnitine palmitoyltransferase 1A; ER; estrogen receptor; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLS; glutaminase; GLUT1; glu

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-155 induces autophagy in osteoclasts by targeting transforming growth factor β-activated kinase 1-binding protein 2 upon lipopolysaccharide stimulation

Keywords: ریکتور; BMM; bone marrow-derived macrophages; M-CSF; macrophage-colony stimulating factor; miR; microRNA; miR-155; microRNA-155; MNC; multinucleated cells; OC; osteoclast; PBS; phosphate-buffered saline; qPCR; quantitative polymerase chain reaction; RANKL; recept

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells

Keywords: ریکتور; FKBP12; FK506 binding protein 12 kDa; FRB domain; FKBP12-rapamycin binding domain; mTOR; mammalian target of rapamycin; mTORC1/2; mTOR complex 1/2; NF-κB; nuclear factor-κB; Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

IL-13 enhances mesenchymal transition of pulmonary artery endothelial cells via down-regulation of miR-424/503 in vitro

Keywords: ریکتور; Interleukin 13 (IL-13); MicroRNA-424/503; Rictor; Histone deacetylase (HDAC); Pulmonary arterial hypertension (PAH);

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

ZBTB38, a novel regulator of autophagy initiation targeted by RB1CC1/FIP200 in spinal cord injury

Keywords: ریکتور; ATG2; autophagy-related protein 2; ATG13; autophagy-related protein 13; ATG14; autophagy-related protein 14; ATG101; autophagy-related protein 101; ATM; ataxia telangiectasia-mutated gene; BECN1; the homologue of yeast autophagy-related protein 6; CCK-8;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

Keywords: ریکتور; Epilepsy; Rapamycin; Everolimus; Pharmacokinetics; Tolerability; Levetiracetam; AKT; protein kinase B; ASD; anti-seizure drug; 4E-BP1; initiation factor 4E binding protein; HPβCD; hydroxypropyl-ß-cyclodextrin; MTD; maximal tolerated dose; MES-T; maximal

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2)

Keywords: ریکتور; Oxidative stress; Reactive oxygen species; Peroxiredoxin-3; Mammalian target of rapamycin (mTORC2); Rictor; Insulin resistance; Akt; Adipocytes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

GSK3 inhibitor AR-A014418 promotes osteogenic differentiation of human adipose-derived stem cells via ERK and mTORC2/Akt signaling pathway

Keywords: ریکتور; AR-A014418; Human adipose-derived stem cells (hASCs); Osteogenic differentiation; GSK3; ERK1/2; RICTOR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial toxicity of perfluorooctane sulfonate in mouse embryonic stem cell-derived cardiomyocytes

Keywords: ریکتور; Perfluorooctane sulfonate (PFOS); Embryonic stem cell-derived cardiomyocytes (ESC-CMs); Ca2+; Mitochondria; Rictor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Therapeutic implication of mTORC2 in oral squamous cell carcinoma

Keywords: ریکتور; mTORC2; Rictor; SGK1; Torin-1; Cetuximab;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

miR-148a-3p regulates adipocyte and osteoblast differentiation by targeting lysine-specific demethylase 6b

Keywords: ریکتور; ALP; alkaline phosphatase; aP2; adipocyte protein 2; BMP2; bone morphogenetic protein 2; C/EBP; CCAAT/enhancer binding protein; Dlx5; distal-less homeobox 5; HDAC9; Histone deacetylase 9; miRNA; microRNA; MSC; mesenchymal stem cell; Osx; osterix; PBS; pho

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression

Keywords: ریکتور; Liver Cancer; Signal Transduction; Tumorigenesis; Oncogene; AKT; v-akt murine thymoma viral oncogene homolog; CHKA; choline kinase α; EGFR; epidermal growth factor receptor; ERK; extracellular regulated kinase; GFP; green fluorescent protein; HCC; hepato

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

Keywords: ریکتور; Ceramide; NAFLD; Rictor; Western diet;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice

Keywords: ریکتور; Estrogens; Estrogen receptor; Steroid receptor coactivator-1; mTORC2; Rictor; Actin polymerization; Spatial learning;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

The mTORC2/PKC pathway sustains compensatory insulin secretion of pancreatic β cells in response to metabolic stress

Keywords: ریکتور; βRicKO; β-cell-specific knockout of Rictor; GIIS; glucose-induced insulin secretion; HFD; high-fat diet; NCD; normal chow diet; mTOR; mechanistic target of rapamycin; mTORC2; mTOR complex 2; PKC; protein kinase C; PMA; phorbol 12-myristate 13-acetate; R

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: ریکتور; AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Keywords: ریکتور; Sulforaphane (PubChem CID: 5350); Dimethyl Sulfoxide (PubChem CID: 679); ARE; antioxidant response element; CREB; cAMP-response element-binding protein; DAB; diaminobenzidine; DMSO; dimethyl sulfoxide; 4E-BP1; eukaryotic translation initiation factor 4E-b

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse

Keywords: ریکتور; Rictor; mTORC2; Wnt; Sost; Bone; Osteoblast; Osteoclast

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Rictor/mTORC2 loss in osteoblasts impairs bone mass and strength

Keywords: ریکتور; Rictor; mTORC2; Osteoblasts; Osteoclasts; Bone remodeling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

Keywords: ریکتور; Rictor; mTORC2; Foxo1; CD8 T cell; infection

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells

Keywords: ریکتور; 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer

Keywords: ریکتور; Gastric cancer; Rictor; pAktSer473; pS6; Prognosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma

Keywords: ریکتور; Colorectal cancer; MDR; Raptor; Rictor; Beclin1; Prognosis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

mTOR and its tight regulation for iNKT cell development and effector function

Keywords: ریکتور; iNKT cell; mTOR; Raptor; Rictor; TSC1/2; Diacylglycerol kinases; RasGRP1; PTEN; Ras; CARMA1; iNKT1; iNKT2; iNKT17; Signal transduction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Keywords: ریکتور; Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive companion of mTOR; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; m-TORC2; mTOR complex 2; Sp1; specific protein 1; MTH; mithramycin; RAPA; rapamycin; ChIP; chromat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Gβγ interacts with mTOR and promotes its activation

Keywords: ریکتور; Gβγ; G-protein; mTOR; AKT; G-protein coupled receptor; Raptor; Rictor; Cell signaling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

Keywords: ریکتور; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; caRags; constitutively active Rags B and C; caRheb; constitutively active Rheb; caRhoA; constitutively active RhoA; mTOR; mechanistic target of rapamycin; mTORC; mechanistic target of rapamycin co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways

Keywords: ریکتور; EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; mTOR; mammalian target of rapamycin; mTORC2; mTOR complex 2; RMAECs; rat mesenteric arterial endothelial cells; rTERT; rat telomerase reverse transcriptase; SA-β-gal; senescence-as

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

Keywords: ریکتور; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Keywords: ریکتور; Akt1; v-akt murine thymoma viral oncogene homolog 1; AMBRA; Autophagy/Beclin-1 regulator 1; AMPK; AMP-dependent protein kinase; ATG; autophagy-related; BECN1; beclin 1; DEPTOR; DEP domain containing mTOR-interacting protein; EGFR; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

Keywords: ریکتور; Skeletal muscle; Metabolism; Glucose uptake; mTORC2; Rictor; Glycolysis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Keywords: ریکتور; ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis

Keywords: ریکتور; Rictor; mTORC2; CNS insulin; POMC neurons; AgRP neurons; Energy balance; Food intake; Obesity

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury

Keywords: ریکتور; acute kidney injury; cell signaling; cisplatin; Rictor;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR signaling in tumorigenesis

Keywords: ریکتور; mTOR; the mechanistic target of rapamycin or the mammalian target of rapamycin; PIKK; phosphoinositide 3-kinase related protein kinase; ATM; ataxia-telangiectasia mutated; ATR; ataxia-telangiectasia and rad3-related; DNAPK; DNA-dependent protein kinase; R

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Huang-Lian-Jie-Du-Decotion induced protective autophagy against the injury of cerebral ischemia/reperfusion via MAPK-mTOR signaling pathway

Keywords: ریکتور; HLJDD; Huang-Lian-Jie-Du-Decotion; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyltetrazolium chloride; HE; hematoxylin-eosin; NO; nitric oxide; MDA; malondialdehyde; GSH; glutathione; GSSG; glutathione disulfide; T-SOD; total superoxide di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

IKK interacts with rictor and regulates mTORC2

Keywords: ریکتور; The IκB kinase; Rictor; The mammalian target of rapamycin complex 2;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development

Keywords: ریکتور; TOR signaling; RICTOR; SGK-1; SKN-1; Development; C. elegans

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells

Keywords: ریکتور; Rictor; FBXW7; c-Myc; Cyclin E; Colorectal cancer cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

mTOR inhibitors in cancer therapy

Keywords: ریکتور; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC; mammalian target of rapamycin complex; Raptor; regulatory-associated protein of mTOR; S6K1; S6 kinase 1, 4E-BP1, 4E-binding protein 1; Rictor; rapamycin-insensitive companion

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Rictor-dependent AKT activation and inhibition of urothelial carcinoma by rapamycin

Keywords: ریکتور; AKT; Rapamycin; Rictor; Urothelial carcinoma; VEGF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8

Keywords: ریکتور; mTOR; LST8; Raptor; Rictor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum is a main localization site of mTORC2

Keywords: ریکتور; mTOR (mammalian Target of Rapamycin); mTORC2 (mTOR Complex 2); Rictor; Cell signaling; Endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The 14-3-3 proteins in regulation of cellular metabolism

Keywords: ریکتور; 4E-BP1; eIF4E-binding protein 1; AANAT; arylalkylamine N-acetyltransferase; ACC; acetyl-CoA carboxylase; AKT; protein kinase B; AMPK; AMP dependent protein kinase; AS; ATP synthase; AS160; AKT substrate 160; ATG; autophagy related; BAD; Bcl-2 antagonist o

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه