دانلود مقالات ISI درباره Rrm1 + ترجمه فارسی

Original ArticlemicroRNA-210 overexpression inhibits tumor growth and potentially reverses gemcitabine resistance in pancreatic cancer

Keywords: Pancreatic cancer; microRNA; Multi drug resistance; Novel therapeutics; Bx-GEM; gemcitabine resistant BxPC3 subclone; CAM; chorioallantoic membrane; miR; micro-RNA; PDA; pancreatic ductal adenocarcinoma; RRM1; ribonucleotide reductase sub-unit M1; 3′ UT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein

Keywords: 3TC; lamivudine; cccDNA; covalently-closed-circular DNA; CI; combination index; CMC; Comprehensive Medicinal Chemistry; Gem; gemcitabine; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HU; hydroxyurea; NDPs; ribonucleoside diphosphates; dNDPs; deo

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

Potent effect of adenoviral vector expressing short hairpin RNA targeting ribonucleotide reductase large subunit M1 on cell viability and chemotherapeutic sensitivity to gemcitabine in non-small cell lung cancer cells

Keywords: RRM1; shRNA; Adenovirus; Gene therapy; Gemcitabine; Chemotherapeutic sensitivity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Importance of excision repair cross-complementation group 1 and ribonucleotide reductase M1 as prognostic biomarkers in malignant pleural mesothelioma treated with platinum-based induction chemotherapy followed by surgery

Keywords: 10.1; 29; 14; ERCC1; RRM1; mesothelioma; multimodality treatment; prognostic factor; EPP; extrapleural pneumonectomy; ERCC1; excision repair cross-complementation group 1; FFR; freedom from recurrence; MPM; malignant pleural mesothelioma; NSCLC; non-sma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress

Keywords: RRM1; Centrosome integrity; Replication fork stalling; DNA damage; Tumor suppressor; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Phase II trial of customized first line chemotherapy according to ERCC1 and RRM1 SNPs in patients with advanced non-small-cell lung cancer

Keywords: Non-small-cell lung cancer; Chemotherapy; Polymorphisms; SNPs; ERCC1; RRM1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

Keywords: TDP-43; trans-activation region DNA-binding protein of 43-kDa; RRM; RNA recognition motif; ALS; amyotrophic lateral sclerosis; FTLD; frontotemporal lobar degeneration; AD; Alzheimer's disease; PD; Parkinson's disease; HD; Huntington's disease; NTD;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Histology-Related Associations of ERCC1, RRM1, and TS Biomarkers in Patients with Non–Small-Cell Lung Cancer: Implications for Therapy

Keywords: Biomarkers in NSCLC; Personalized treatment; ERCC1; RRM1; TS; Histology; Sex

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: A meta-analysis

Keywords: RRM1; Gemcitabine; NSCLC; Meta-analysis; Median survival; Time to progression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Modulation of the ribonucleotide reductase M1-gemcitabine interaction in vivo by N-ethylmaleimide

Keywords: RRM1; Gemcitabine; N-ethylmaleimide;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Phase II Trial of Induction Gemcitabine and Carboplatin Followed by Conformal Thoracic Radiation to 74 Gy with Weekly Paclitaxel and Carboplatin in Unresectable Stage III Non-small Cell Lung Cancer

Keywords: Non-small-cell lung cancer; Conformal radiation; Gemcitabine; Carboplatin; Paclitaxel; ERCC1; RRM1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation

Keywords: Rrm1; muscle ribonucleotide reductase 1; Rrm2; muscle ribonucleotide reductase 2; ARC; adult rat cardiomyocyte; GFP; green fluorescent protein; RT50; RT90, time to 50% and 90% relaxation; DT50; DT90, time to 50% and 90% Ca2+ decay; Cardiomyocyte; Contract

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Differential Effect of Polymorphisms of CMPK1 and RRM1 on Survival in Advanced Non-small Cell Lung Cancer Patients Treated with Gemcitabine or Taxane/Cisplatinum

Keywords: CMPK1; Non-small cell lung cancer; Pharmacogenetics; Platinum; RRM1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

The immunohistochemical overexpression of ribonucleotide reductase regulatory subunit M1 (RRM1) protein is a predictor of shorter survival to gemcitabine-based chemotherapy in advanced non-small cell lung cancer (NSCLC)

Keywords: Chemotherapy; Gemcitabine; Immunohistochemistry; NSCLC; RRM1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The role of βIII tubulin in predicting chemoresistance in non-small cell lung cancer

Keywords: Non-small cell lung cancer; Biomarker; Tubulin; ERCC1; RRM1; Tubulin-binding agent; Taxane; Epothilone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Parameters for individualizing systemic therapy in non-small cell lung cancer

Keywords: Lung cancer; ERCC1; RRM1; TS; EGFR; EML4-ALK; Crizotinib; Bevacizumab;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Polymorphisms of the ribonucleotide reductase M1 gene and sensitivity to platin-based chemotherapy in non-small cell lung cancer

Keywords: Non-small cell lung cancer; RRM1; Genetic polymorphism; Platinum; Chemotherapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Metastasis suppressors genes in cancer

Keywords: Cancer; Metastasis; Metastasis suppressor; Signaling; Tumor; BRMS1; Cadherins; CD44; DLC1; Drg1; Gelsolin; KAI1; KISS1; MKK4; Nm23; RhoGDI2; RKIP; RRM1; SSeCKS

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

Pharmacogenomics: A reality or still a promise?

Keywords: Chromosome 11p15.5; ERCC1; Gemcitabine; Immunohistochemistry; NSCLC; Pharmacogenomics; RRM1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance

Keywords: RRM1; Ribonucleotide reductase; Promoter; Polymorphisms; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه