دانلود مقالات ISI درباره S1P، اسپینگوزین 1-فسفات + ترجمه فارسی

Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice

Keywords: S1P، اسپینگوزین 1-فسفات; Atopic dermatitis; Epidermal barrier function; Filaggrin; FTY720 ointment; NC/Nga miceAD, atopic dermatitis; Df, Dermatophagoides farinae crude extract; Ig, immunoglobulin; S1P, sphingosine 1-phosphate; SC, stratum corneum; TEWL, transepidermal water loss

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Depletion of T lymphocytes ameliorates cardiac fibrosis in streptozotocin-induced diabetic cardiomyopathy

Keywords: S1P، اسپینگوزین 1-فسفات; KO, knockout; Rag1, recombination activating gene 1; S1P, sphingosine 1-phosphate; S1P1, sphingosine 1-phosphate receptor 1; STZ, streptozotocin; TGF-β1, transforming growth factor beta 1; WT, wild-typeFingolimod (FTY720); Sphingosine 1-phosphate; T lymph

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Non-genomic rapid responses via progesterone in human peripheral T cells are not indirectly mimicked by sphingosine 1-phosphate

Keywords: S1P، اسپینگوزین 1-فسفات; mPRs, membrane progesterone receptors; PAQRs, progestin and adipoQ receptors; S1P, sphingosine 1-phosphate; [Ca2+]i, intracellular free calcium concentration; pHi, intracellular pHNon genomic; Progesterone; T-cells; Sphingosine 1-phosphate; Membrane stero

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Lipoprotein-associated lysolipids are differentially involved in high-density lipoprotein- and its oxidized form-induced neurite remodeling in PC12 cells

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, sphingosine 1-phosphate; LPA, lysophosphatidic acid; S1P1–5, S1P receptor type 1–5; LPA1–6, LPA receptor type 1–6; LPC, lysophosphatidylcholine; HDL, high-density lipoprotein; oxHDL, oxidized HDL; LDL, low-density lipoprotein; NGF, nerve growth facto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Development of a selective S1P1 receptor agonist, Syl930, as a potential therapeutic agent for autoimmune encephalitis

Keywords: S1P، اسپینگوزین 1-فسفات; S1P1, sphingosine-1-phosphate receptor subtype 1; S1P3, sphingosine-1-phosphate receptor subtype 3; S1P, sphingosine 1-phosphate; EAE, experimental autoimmune ancephalomyelitis; PBL, periphery blood lymphocytes; MS, multiple sclerosis; CNS, central nervou

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells

Keywords: S1P، اسپینگوزین 1-فسفات; HCC, hepatocellular carcinoma; SphK1, sphingosine kinase 1; S1P, sphingosine 1-phosphate; S1PR1-5, S1P receptor type1-5; CI, combination index; Fa, fraction affected; FAK, focal adhesion kinase; MLC-2, myosin light chains-2Sphingosine kinase 1; ERK; N-ras

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R−/−) mice

Keywords: S1P، اسپینگوزین 1-فسفات; ConA, concanavalin A; DMEM, Dulbecco-modified Eagle's medium; FCS, fetal calf serum; HDL, high density lipoproteins; LDL-R, low density lipoprotein receptor; LPS, lipopolysaccharide; S1P, sphingosine 1-phosphate; PBS, phosphate-buffered saline; S1PR1, S1P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Bortezomib and sphingosine kinase inhibitor interact synergistically to induces apoptosis in BCR/ABl+ cells sensitive and resistant to STI571 through down-regulation Mcl-1

Keywords: S1P، اسپینگوزین 1-فسفات; SPK1, sphingosine kinase 1; S1P, sphingosine 1-phosphate; SKI, sphingosine kinase inhibitor; DMS, N,N-dimethylsphingosine; CML, chronic myelogenous leukemia; MEK, mitogenactivated protein kinase; ERK, extracellular signal regulating kinase; Mcl-1, myeloid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS)

Keywords: S1P، اسپینگوزین 1-فسفات; So, sphingosine; S1P, sphingosine 1-phosphate; Sa, sphinganine; Sa1P, sphinganine 1-phosphate; 1-doxSo, 1-deoxysphingosine; 1-doxSa, 1-deoxysphinganine; 1-demeoxSo, 1-desmethoxysphingosine; 1-demeoxSa, 1-desmethoxysphinganine; Cer, ceramide; Cer1P, cerami

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

UPLC–MS/MS method for analysis of sphingosine 1-phosphate in biological samples

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, sphingosine 1-phosphate; C17-S1P, C17-sphingosine 1-phosphate; DH-S1P, sphinganine 1-phosphate; SPH, sphingosine; UPLC, ultra-performance liquid chromatography; ESI−, negative electron spray ionization; MS, mass spectrometry; MRM, multiple reaction m

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic β-cells

Keywords: S1P، اسپینگوزین 1-فسفات; MAPK, mitogen-activated protein kinase; S1P, sphingosine 1-phosphate; S1P2, sphingosine 1-phosphate receptor 2; STZ, streptozotocin; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; WT, wild-typeBlood glucose; Diabetes; Insuli

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Sphingosine kinase 1 regulates mucin production via ERK phosphorylation

Keywords: S1P، اسپینگوزین 1-فسفات; Sphingosine 1-phosphate; Sphingosine kinase; Airway epithelium; IL-13; ERKSphK, sphingosine kinase; S1P, sphingosine 1-phosphate; IL, interleukin; DMS, N,N-dimethylsphingosine; MAPK, mitogen-activated kinase; ERK, extracellular signal-regulated kinase; ST

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model

Keywords: S1P، اسپینگوزین 1-فسفات; DC, dendritic cell; S1P, sphingosine 1-phosphate; Tregs, regulatory T cells; MLR, mixed lymphocyte reaction; RA, rheumatoid arthritisCD4+ T cell; FTY720; Rheumatoid arthritis; SKG mouse

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Hemolysis induced by Bacillus cereus sphingomyelinase

Keywords: S1P، اسپینگوزین 1-فسفات; B. cereus, Bacillus cereus; Bc-SMase, Bacillus cereus sphingomyelinase; C. perfringens, Clostridium perfringens; DRM, detergent-resistant membranes; DSF, detergent-soluble fractions; SM, sphingomyelin; S1P, sphingosine 1-phosphate; MβCD, methyl-β-cyclodex

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells

Keywords: S1P، اسپینگوزین 1-فسفات; ccPA, 2-carbocyclic phosphatidic acid; FCS, fetal calf serum; LPA, lysophosphatidic acid; S1P, sphingosine 1-phosphate; SRB, sulforhodamine BAutotaxin; Ovarian; Drug resistance; RNAi; Carboplatin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Lysophospholipids enhance taurine release from rat retinal vascular endothelial cells under hypoosmotic stress

Keywords: S1P، اسپینگوزین 1-فسفات; BRB, blood-retinal barrier; DMEM, Dulbecco's modified Eagle's medium; LPA, lysophosphatidic acid; PKC, protein kinase C; RVEC, retinal vascular endothelial cell; S1P, sphingosine 1-phosphate; VSOAC, volume-sensitive organic osmolyte and anion channelInner

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, Sphingosine 1-phosphate; SphK, Sphingosine kinase; PMA, Phorbol 12-myristate 13-acetate; TNFα, Tumor necrosis factor α; EGF, Epidermal growth factor; ERK, Extracellular signal-regulated kinase; S1P1–5, S1P receptor type 1–5; PA, Phosphatidic acid; PL

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity

Keywords: S1P، اسپینگوزین 1-فسفات; S, sphingosine; S1P, sphingosine 1-phosphate; GPCR, G protein-coupled receptor; S1P1, type 1 GPCR for S1P; TG, transgenic; WT, wild-type; TCR, T cell antigen receptor; OVA, a distinct substituent peptide epitope of ovalbumin; OTII, a line of C57BL/6 mice

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, sphingosine 1-phosphate; FTY720-P, FTY720 phosphate; HDL, high-density lipoprotein; ABC, ATP-binding cassetteSphingosine 1-phosphate; FTY720; Erythrocyte; Platelet; Immunomodulator; Sphingolipid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Phenotypic and functional heterogeneity of human memory B cells

Keywords: S1P، اسپینگوزین 1-فسفات; RSV, respiratory syncytial virus; BCDT, B cell depletion therapy; MZ, marginal zone; S1P, sphingosine 1-phosphate; S1P1, S1P receptor 1B cells; Effector memory; Central memory; Marginal zone; Homeostasis

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

Functions of sphingolipid metabolism in mammals — Lessons from genetic defects

Keywords: S1P، اسپینگوزین 1-فسفات; GalCer, galactosylceramide; GlcCer, glucosylceramide; GSL, glycosphingolipid; iNKT cells, invariant natural killer T cells; LacCer, lactosylceramide; S1P, sphingosine 1-phosphate; SL, sphingolipid; SM, sphingomyelin; SMase, sphingomyelinase; SPC, sphingos

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2008 سفارش ترجمه

Tumor necrosis factor-α exerts pro-myogenic action in C2C12 myoblasts via sphingosine kinase/S1P2 signaling

Keywords: S1P، اسپینگوزین 1-فسفات; TNFα, tumor necrosis factor-α; SphK, sphingosine kinase; S1P, sphingosine 1-phosphate; MHC, myosin heavy chain; siRNA, short interfering RNA; SKI, sphingosine kinase inhibitor; WTSphK1, wild-type SphK1; DNSphK1, catalytically inactive SphK1Tumor necrosis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of direct albumin binding to sphingosylphosphorylcholine in Jurkat T cells

Keywords: S1P، اسپینگوزین 1-فسفات; SPC, sphingosylphosphorylcholine; S1P, sphingosine 1-phosphate; LPC, lysophosphatidylcholine; LPA, lysophosphatidic acid; LPE, lysophosphatidylethanolamine; LPS, lysophosphatidylserine; BSA, bovine serum albumin; FBS, fetal bovine serum; MTT, 3-[4,5-dimet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Sphingosine 1-phosphate pKa and binding constants: Intramolecular and intermolecular influences

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, sphingosine 1-phosphate; IEF-PCM, C-PCM conductor-like polarization continuum model; GPCR, G protein-coupled receptor; EDG, endothelial differentiation gene; DFT, density functional theory; DMEM, Dulbecco's modified minimal essential medium; RH7777,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts

Keywords: S1P، اسپینگوزین 1-فسفات; IGF-1, insulin-like growth factor 1; S1P, sphingosine 1-phosphate; S1PR, sphingosine 1-phosphate receptors; PBS, phosphate-buffered saline, FCS fetal calf serum; BSA, bovine serum albumin; ODN, oligodeoxyribonucleotides; siRNA, small interfering RNA; ECL,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Lysophospholipids elevate [Ca2+]i and trigger exocytosis in bovine chromaffin cells

Keywords: S1P، اسپینگوزین 1-فسفات; Lysophospholipid; Intracellular Ca2+ stores; Exocytosis; Ca2+ current; CapacitanceCICR, calcium-induced calcium release; LPA, lysophosphatidic acid; LPL, lysophospholipid; PLC, phospholipase C; Ptx, pertussis toxin; S1P, sphingosine 1-phosphate; Tg, thaps

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells

Keywords: S1P، اسپینگوزین 1-فسفات; S1P, sphingosine 1-phosphate; VCAM-1, vascular cell adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1; HUVECs, human umbilical vein endothelial cells; NO, nitric oxide; eNOS, endothelial NO synthase; TNF-α, tumor necrosis factor-α; NF-κB, nuc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

The leucine 10 residue in the pleckstrin homology domain of ceramide kinase is crucial for its catalytic activity

Keywords: S1P، اسپینگوزین 1-فسفات; Cer, ceramide; Sph, sphingosine; CERK, ceramide kinase; SPHK, sphingosine kinase; C1P, ceramide 1-phosphate; S1P, sphingosine 1-phosphate; PH, pleckstrin homology; DGK, diacylglycerol kinase; PIP, phosphatidylinositol phosphateCeramide kinase; Ceramide; C

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells

Keywords: S1P، اسپینگوزین 1-فسفات; ChIP, chromatin immunoprecipitation; CTGF, connective tissue growth factor; GPCR, G protein-coupled receptor; PT, pertussis toxin; S1P, sphingosine 1-phosphate; TGF-β, transforming growth factor-βSphingosine 1-phosphate; Connective tissue growth factor; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه