Keywords: SAM، S-آدنوزیل متیونین; Fruit development; Polyamine biosynthesis; Polyamine catabolism; Arginine decarboxylase; Ornithine decarboxylase; Copper containing amine oxidase; Expression analysisPut, Putrescine; Spd, Spermidine; Spm, Spermine; SAM, S-adenosylmethionine; ODC, Ornithin
مقالات ISI SAM، S-آدنوزیل متیونین (ترجمه نشده)
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Keywords: SAM، S-آدنوزیل متیونین; SZ, schizophrenia; C1, one-carbon; Hcy, homocysteine; ROS, reactive oxygen species; SAM, S-adenosylmethionine; DNMT, DNA methyltransferase; FFQ, food frequency questionnaire; 24HDR, 24-hour dietary recall; RBC, red blood cell; SD, standard deviation; WMD,
Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue
Keywords: SAM، S-آدنوزیل متیونین; 5-HIAA, 5-hydroxyindoleacetic acid; 5-methylTHF, 5-methyltetrahydrofolate; COMT, catechol-O-methyltransferase; HPLC, high performance liquid chromatography; MTHFR, methylenetetrahydrofolate reductase; SAM, S-adenosylmethionine; GABA, γ-aminobutyric acid;
Molecular cloning and characterization of an S-adenosylmethionine synthetase gene from Chorispora bungeana
Keywords: SAM، S-آدنوزیل متیونین; SAMS, S-adenosylmethionine synthetase; SAM, S-adenosylmethionine; NES, nuclear export signal; GUS, beta-glucuronidase; C. bungeana, Chorispora bungeana; LTR, low temperature responsivenessS-adenosylmethionine synthetase; Low temperature response; Chorispo
Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G polymorphisms influence on leukocyte genomic DNA methylation level
Keywords: SAM، S-آدنوزیل متیونین; BHMT, betaine-homocysteine S-methyltransferase; MTHFR, methylenetetrahydrofolate reductase; MTR, methionine synthase; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; OD, optical density; PCR, polymerase chain reactionMethionine synthase; Methylene
Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet
Keywords: SAM، S-آدنوزیل متیونین; FAS, fatty acid synthase; ACC, acetyl-CoA carboxylase; PPARα, peroxisomal proliferator-activated receptor alpha; ACOX, acyl-CoA oxidase; MTTP, microsomal triglyceride transfer protein; ApoB, apolipoprotein B; SAM, S-adenosylmethionine; SAH, S-adenosylhomo
Dietary intake, plasma homocysteine, and repetitive element DNA methylation in the Multi-Ethnic Study of Atherosclerosis (MESA)
Keywords: SAM، S-آدنوزیل متیونین; DNA methylation; Cardiovascular disease; Homocysteine; LINE-1; Alu; Obesity; HeightLINE-1, long interspersed nucleotide element-1; BMI, body mass index; CVD, cardiovascular disease; MESA, Multi-Ethnic Study of Atherosclerosis; SAM, S-adenosylmethionine; F
Homocysteine and DNA methylation: A review of animal and human literature
Keywords: SAM، S-آدنوزیل متیونین; Hcy, homocysteine; HHcy, hyperhomocysteinemia; HH, hyperhomocysteinemic; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; HM, high methionine; MD, methionine deficient; LF, low folate; LB6, low vitamin B6; LB12, low vitamin B12; FD, folate deficien
Mutation of EMG1 causing Bowen–Conradi syndrome results in reduced cell proliferation rates concomitant with G2/M arrest and 18S rRNA processing delay
Keywords: SAM، S-آدنوزیل متیونین; BCS, Bowen–Conradi syndrome; EMG1, Essential for Mitotic Growth 1; snoRNA, small nucleolar RNA; SAM, S-adenosylmethionine; m1acp3-ψ, N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine; CPM, counts per minute; IRES, internal ribosomal entry site.Ribosome
Functional evaluation of Asp76, 84, 102 and 150 in human arsenic(III) methyltransferase (hAS3MT) interacting with S-adenosylmethionine
Keywords: SAM، S-آدنوزیل متیونین; iAs, inorganic arsenic; MMA, monomethylated arsenicals; DMA, dimethylated arsenicals; AS3MT, arsenic(III) methyltransferase; SAM, S-adenosylmethionine; GSH, glutathione; CD, circular dichroism; BSA, bovine serum albumin; isopropyl, β-d-thiogalactopyranosi
DNA methylation of the 5′-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells
Keywords: SAM، S-آدنوزیل متیونین; AD, Alzheimer’s disease; Aβ, β-amyloid peptides; APP, amyloid precursor protein; MCI, mild cognitive impairment; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; 5-Aza, 5-aza-2′-deoxycytidine; 5′-UTR, 5′-untranslated region; pCpGL-BACE1, BACE1 gene
Enzyme catalyzed formation of radicals from S-adenosylmethionine and inhibition of enzyme activity by the cleavage products
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; DOA•, 5′-deoxyadenosine radical; MTA, 5′-methylthioadenosine; ACP•, 3-amino-3-carboxypropyl radical; GRE, glycyl radical enzyme; XAS, X-ray absorption spectroscopy; PLP, 5′-pyridoxal phosphate; DTB, dethiobiotin; SAH, S-adenosyl
Ethanol exposure modulates hepatic S-adenosylmethionine and S-adenosylhomocysteine levels in the isolated perfused rat liver through changes in the redox state of the NADH/NAD+ system
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; MAT, methionine adenosyltransferase; SAHH, S-adenosylhomocysteine hydrolase; G + M, glucose + methionine; 4-MP, 4-methylpyrazole; Pyr, pyruvate; EtOH, ethanol; Prop, propanolPerfused rat liver; Alcohol; Redox state; Methionine m
Homocysteine levels impact directly on epigenetic reprogramming in astrocytes
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; Hcys, homocysteine; DNMT, DNA methyltransferase; NMDA, N-methyl-d-aspartate; mGluR, metabotropic glutamate receptorsAstrocytes; Epigenetics; DNA methylation; Homocysteine
Thymidylate synthase gene polymorphisms and markers of DNA methylation capacity
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; ATP, adenosine triphosphate; SAH, S-adenosylhomocysteine; SAHH, S-adenosylhomocysteine hydrolase; 5-methyl-THF, 5-methylenetetrahydrofolate; MS, methionine synthase; 5,10-methylene-THF, 5,10-methylenetetrahydrofolate; TS, thymid
The biological significance of methionine sulfoxide stereochemistry
Keywords: SAM، S-آدنوزیل متیونین; GSH, Glutathione; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; CBS, Cystathionine β-synthase; MS, Methionine synthase; ROS, Reactive oxygen species; Met-R-SO, Methionine-R-sulfoxide; Met-S-SO, Methionine-S-sulfoxide; Msr, Methionine sulfoxide r
Oxidative stress is implicated in arsenic-induced neural tube defects in chick embryos
Keywords: SAM، S-آدنوزیل متیونین; SA, sodium arsenite; NTDs, neural tube defects; NAC, N-acetyl-l-cysteine; ROS, reactive oxygen species; SOD, superoxide dismutase; GPX, glutathione peroxidase; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; 5-mec, 5-mecthylcystidineSodium arsenit
An overview of epigenetics and chemoprevention
Keywords: SAM، S-آدنوزیل متیونین; DNMT, DNA methyltransferase; SAM, S-adenosylmethionine; HAT, histone acetylase; HDAC, histone deacetylase; MBD, methyl-CpG-binding domain; IBD, inflammatory bowel disease; SFRP, secreted frizzled-related protein; APC, adenomatous polyposis coli; ACF, aber
Creatine metabolism and the urea cycle
Keywords: SAM، S-آدنوزیل متیونین; GAA, guanidinoacetate; SAM, S-adenosylmethionine; SAH, S-adenosyl homocysteine; ROS, reactive oxygen species; AGAT, l-arginine:glycine amidinotransferase; GAMT, guanidinoacetate methyltransferase; UCD, urea cycle disorderGuanidinoacetate; Gyrate atrophy;
Impaired methylation as a novel mechanism for proteasome suppression in liver cells
Keywords: SAM، S-آدنوزیل متیونین; MHC, major histocompatibility complex; CYP2E1, cytochrome P450 2E1; ADH, alcohol dehydrogenase; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; TBARS, Thiobarbituric Acid Reactive Substances; Cht-L, proteasome chymotrypsin-like activity; ROS, reac
Influence of thymidylate synthase gene polymorphisms on total plasma homocysteine concentrations
Keywords: SAM، S-آدنوزیل متیونین; tHcy, total plasma homocysteine; 5-methyl-THF, 5-methyltetrahydrofolate; MS, methionine synthase; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; TS, thymidylate synthase; UTR, untranslated region; TSER, thymidylate synthase enhancer region; G/C S
Reduced de novo synthesis of 5-methyltetrahydrofolate and reduced taurine levels in ethanol-treated chick brains
Keywords: SAM، S-آدنوزیل متیونین; FAD+, flavin adenine dinucleotide; 10-FTHF DH, 10-formyltetrahydrofolate dehydrogenase; HoCys, homocysteine; MTHFR, N5, N10-methylenetetrahydrofolate reductase; SAH, s-adenosylhomocysteine; SAM, s-adenosylmethionine; 5-methyl THF, 5-methyltetrahydrofolate
Epigenetic regulation in the pathophysiology of Alzheimer's disease
Keywords: SAM، S-آدنوزیل متیونین; AD, Alzheimer's disease; APP, amyloid-precursor protein; PS, presenilin; fAD, familial AD; Apo, Apolipoprotein; sAD, sporadic AD; Aβ, beta-amyloid; SAM, s-adenosylmethionine; C, cytosine; G, guanine; DNMT, DNA methyltransferase; SAH, s-adenylohomocysteine
Micronutrients in Parenteral Nutrition: Boron, Silicon, and Fluoride
Keywords: SAM، S-آدنوزیل متیونین; AI, adequate intake; B, boron; F, fluoride; PN, parenteral nutrition; SAM, S-adenosylmethionine; SI, silicon
α-Lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine
Keywords: SAM، S-آدنوزیل متیونین; LA, α-lipoic acid; DHLA, dihydrolipoic acid; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; SAHH, S-adenosylhomocysteine hydrolase; CBS, cystathionine β-synthase; DTT, dithiothreitol; tHcys, total homocysteine; ip, intraperitoneal; MESNA, sodium
Epigenetic mechanisms in the biology of prostate cancer
Keywords: SAM، S-آدنوزیل متیونین; PSA, prostate-specific antigen; H3K9, histone H3 lysine 9; PcG, polycomb group protein; HMT, histone methyltransferase; HDAC, histone deacetylase; ESC, embryonic stem cell; DNMT, DNA methyltransferase; SAM, S-adenosylmethionine; AR, androgen receptorDNA m
Structural and Functional Divergence within the Dim1/KsgA Family of rRNA Methyltransferases
Keywords: SAM، S-آدنوزیل متیونین; 5-FOA, 5-fluoroorotic acid; SAM, S-adenosylmethionine; NLS, nuclear localization signal; PEG, polyethylene glycolDim1; KsgA; archaea; dimethyltransferase; rRNA methylation
Heme oxygenase-1 is a novel target and antioxidant mediator of S-adenosylmethionine
Keywords: SAM، S-آدنوزیل متیونین; Act D, actinomycin D; AD, Alzheimer’s disease; CHX, cycloheximide; HO, heme oxygenase; ROS, reactive oxygen species; SAM, S-adenosylmethionine; ZnBG, zinc deuteroporphyrin IX 2,4-bis-ethylene glycolAntioxidant; Endothelial cells; Ferritin; Heme oxygenase-
Effect of the methylenetetrahydrofolate reductase gene polymorphisms on homocysteine, folate and vitamin B12 in patients with bipolar disorder and relatives
Keywords: SAM، S-آدنوزیل متیونین; BD, Bipolar disorder; BPRS, Brief Psychiatric Rating Scale; FPIA, Fluorescence Polarization Immunoassay; MTHFR, methylenetetrahydrofolate; SAM, S-adenosylmethionine; SADS-L, Schedule for Affective Disorders and Schizophrenia-Lifetime; tHcy, total homocyst
Interaction of the Tylosin-resistance Methyltransferase RlmAII at its rRNA Target Differs from the Orthologue RlmAI
Keywords: SAM، S-آدنوزیل متیونین; DMS, dimethyl sulphate; MLSB, macrolide, lincosamide and streptogramin B; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteinerRNA structure; protein–RNA interaction; chemical footprinting; methyltransferases; drug resistance
Methionine intake affect hepatic sulphur metabolism in Atlantic salmon, Salmo salar
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; tHcy, total homocysteine; AA's, amino acids; IAA, indispensable AA's; DAA's, dispensable AA's; TSAA, total sulphuric AA's; IGF, insulin-like growth factor; IGFBP-1, IGF-binding protein-1; GH-R, growt
Plasma folate level, urinary arsenic methylation profiles, and urothelial carcinoma susceptibility
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; UC, urothelial carcinoma; InAs, inorganic arsenic (AsIII + AsV); MMAV, monomethylarsonic acid; DMAV, dimethylarsinic acid; %InAs, inorganic arsenic percentage; %MMAV, monomethylarsonic acid percentage; %DMAV, dimethylarsinic aci
The effect of thiopurine drugs on DNA methylation in relation to TPMT expression
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; DNMT, DNA methyltransferase; DNPS, de novo purine synthesis; TPMT, thiopurine methyltransferase; ATP, adenosine triphosphate; 6-TG, 6-thioguanine; 6-MP, 6-mercaptopurine; rMeMP, 6-methyl-mercaptopuri
Four Human Thiopurine S-Methyltransferase Alleles Severely Affect Protein Structure and Dynamics
Keywords: SAM، S-آدنوزیل متیونین; TPMT, thiopurine S-methyltransferase; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; MD, molecular dynamics; RMSF, root-mean-square fluctuation; B3P, 2-[3-(2-hydroxy-1,1-dihydroxymethyl-ethylamino)-propylamino]-2-hydroxymethyl-propane-1,3-diol; S
Diet and the epigenetic (re)programming of phenotypic differences in behavior
Keywords: SAM، S-آدنوزیل متیونین; HAT, Histone acetyltransferase; HDAC, histone deacetylase; HMT, histone methyltransferase; DNMT, DNA methyltransferase; SAM, S-adenosylmethionine; HDACi, HDAC inhibitor; CBP, CREB binding protein; TSA, Trichostatin A; MBD2, METHYLATED DOMAIN DNA BINDING P
Epigenetic considerations for endometrial cancer prevention, diagnosis and treatment
Keywords: SAM، S-آدنوزیل متیونین; EC, endometrial cancer; DNMT, DNA methyltransferase; SAM, S-adenosylmethionine; CpG, cytosine nucleotide adjacent to guanine; TSG(s), tumor suppressor gene(s); MBDs, methyl-CpG binding domain proteins; HDAC, histone deacetylases; HNPCC, hereditary nonpoly
Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry
Keywords: SAM، S-آدنوزیل متیونین; HPLC, high-performance liquid chromatography; LC–MS, liquid chromatography coupled to mass spectrometry; SRM, selected reaction monitoring; MS/MS, tandem mass spectrometry; NTD, neural tube defects; PFPP, pentafluorophenylpropyl; SAM, s-adenosylmethionine
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; MD, methyl-deficient; MA, methyl-adequate; GSTπ, placental isoform of glutathione-S-transferase; DNMT1, maintenance DNA methyltransferaseMethyl-deficient diet; Methyl-adequate diet; DNA hypomethylati
Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism
Keywords: SAM، S-آدنوزیل متیونین; BChl, bacteriochlorophyll; BChlid, bacteriochlorophyllide; MTase, methyltransferase; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteinecrystal structure; bacteriochlorophyll c; S-adenosylmethionine; reaction mechanism; Chlorobium tepidum
Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima
Keywords: SAM، S-آدنوزیل متیونین; SAM, S-adenosylmethionine; AdoH, 5′-deoxyadenosine; IPTG, isopropyl-β-d-thiogalactopyranoside; DTT, 1,4-dithio-d,l-threitolHydE; HydG; Fe-only hydrogenase; Maturation; Radical-SAM; Sulfur donor
Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by α-naphthylisothiocyanate
Keywords: SAM، S-آدنوزیل متیونین; ALP, alkaline phosphatase; ALT, alanine aminotransferase; ANIT, α-naphthylisothiocyanate; AST, aspartate aminotransferase; BHMT, betaine homocysteine methyltransferase; GSH, glutathione; MAT, methionine adenosyltransferase; SAH, S-adenosylhomocysteine; S