Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention
Keywords: RXR; retinoid X receptor; RAR; retinoic acid receptor; RA; retinoic acid; LBD; ligand binding domain; IBX; 2-iodoxybenzoic acid; RKE; rat kidney epithelial; SCC; squamous cell carcinoma; TG; triglycerides; LBP; ligand binding pocket; THF; tetrahydrofuran;