Keywords: AGEs; advanced glycation end-products; CAD; coronary artery disease; CRP C; reactive protein; CTGF; connective tissue growth factor; DAG; diacyl glycerol; DCM; diabetic cardio-myopathy; DFU; diabetic foot ulcer; eNOS; endothelial nitric oxide synthase; FO
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Keywords: airway epithelium; glucose; metformin; Pseudomonas aeruginosa; Staphylococcus aureus; ASL; airway surface liquid; CF; cystic fibrosis; GLUT; glucose transporter; MRSA; methicillin-resistant Staphylococcus aureus; PPAR; peroxisome proliferator-activated re
Keywords: SGLT; Cerebral ischemia; Cancer; Cardiac disease; Intestinal ischemia;
Keywords: DM; dry matter; CP; crude protein; NDF; neutral detergent fibre; ADF; acid detergent fibre; CF; crude fibre; GE; gross energy; EE; ether extract; NE; net energy; OM; organic matter; N; nitrogen; DE; digestible energy; AOAC; Association of Official Agricul
Keywords: Oral galactose; Streptozotocin; Intracerebroventricular; Sporadic Alzheimer's disease; Memory; Glucagon-like peptide-1; 18fluorodeoxyglucose; APP; amyloid precursor protein; ATP; adenosine triphosphate; Aβ1-42; amyloid β 1-42; CMRgl; cerebral metabolic
Keywords: SGLT; sodium-glucose transporter; DIV; Day in vitro; SBFI; sodium-binding benzofuran isophthalate; STD; standard; PBS; phosphate-buffered saline; BSA; bovine serum albumin; MAP2; microtubule-associated protein 2; DAPI; 4â²,6-diamidino-2-phenylindole; siR
Keywords: blood glucose; cardiovascular disease; heart failure; hypoglycemic agents; outcomes; CI; confidence interval; CV; cardiovascular; CVOT; cardiovascular outcomes trial; GLP; glucagon-like peptide; HbA1c; glycosylated hemoglobin; HR; hazard ratio; MACE; majo
Keywords: Glucose homeostasis; Glucose metabolism; Glucose physiology; Renal glucose metabolism; Glucose transporters; Sodium-glucose co-transporter 2; SGLT2; Diabetes mellitus; FFA; free fatty acids; GLUT; glucose transporter; SGLT; sodium-glucose co-transporter;
Keywords: SGLT2 inhibitor; DPP4 inhibitor; Canagliflozin; Combination treatment; Glucagon-like peptide-1; aGLP-1; active GLP-1; ANOVA; Analysis of variance; AUC; Area under the curve; CMA; (2S)-2-Cyano-1-[trans-4-(morpholinocarbonyl)cyclohexylamino]acetylpyrrolidin
Keywords: FDG-PET; 18F-deoxy-glucose positron emission tomography; 2DG; 2-deoxy-glucose; GLUT; facilitated glucose transporter; SGLT; sodium-coupled glucose co-transporter; DHA; dehydroascorbic acid; HMIT; HÂ +/myo-inositol transporter; PI3K; phosphatidylinositol 3
Keywords: AGE; Advanced Glycation End Products; ddPCR; droplet digital PCR; DHA; docosahexaenoic acid; EC; endothelial cells; eNOS; endothelial Nitric Oxide Synthase; GLUT; glucose transporter; HAoEC; Human Aortic Endothelial Cells; HDMEC; Human Dermal Microendothe
Keywords: FBG; fasting blood glucose; SGLT; sodium-glucose transporter; PHZ; phlorizin; DIV; day in vitro; H2O2; hydrogen peroxide; α-MG; alpha-d-methylglucoside; WST-8; 2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium; MCAO; mi
Keywords: AMPK; 5â²-adenosine monophosphate-activated protein kinase; BSA; bovine serum albumin; DIV; day in vitro; FBG; fasting blood glucose; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; HRP; horseradish peroxidase; i.c
Keywords: ATPase; adenosine triphosphatase; eGFR; estimated glomerular filtration rate; EGP; endogenous glucose production; FPG; fasting plasma glucose; FRG; familial renal glucosuria; GFR; glomerular filtration rate; GGM; glucose-galactose malabsorption; GLP-1; gl
Functional redundancy of glucose acquisition mechanisms in the hindgut of Pacific hagfish (Eptatretus stoutii)
Keywords: Agnatha; Nutrient; Feeding; Transport; SGLT; GLUT;
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk
Keywords: glucose tolerance; Mendelian randomization; SGLT1; BP; blood pressure; CI; confidence interval; DM; diabetes mellitus; FFQ; food frequency questionnaire; GGM; glucose-galactose malabsorption; GLP; glucagon-like peptide; HF; heart failure; HGSC; Human Geno
The role of NADPH oxidases in diabetic cardiomyopathy
Keywords: AGEs; advanced glycation end-products; RAGE; AGE receptors; Ang II; angiotensin II; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; DATS; diallyl trisulfide; ER; endoplasmic reticulum; eNOS and nNOS; endothelial and neuronal nitric oxide synthase;
Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke
Keywords: 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;
Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet
Keywords: Diet-induced obesity; Canagliflozin; Glucagon-like peptide-1; Glucose-dependent insulinotropic polypeptide; Sodium-glucose cotransporter 1(SGLT1); SGLT2 inhibitor; DPP-IV; dipeptidyl peptidase-IV; GLP-1; glucagon-like peptide-1; GIP; Glucose-dependent i
Major constituents of Cistanche tubulosa, echinacoside and acteoside, inhibit sodium-dependent glucose cotransporter 1-mediated glucose uptake by intestinal epithelial cells
Keywords: ACT; acteoside; ECH; echinacoside; GLUT; glucose transporter; SGLT; sodium-dependent glucose cotransporter; 2-NBDG; 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-d-glucose; Cistanche tubulosa; Sodium-dependent glucose cotransporter 1; Glucose uptake
SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice
Keywords: ALT; Alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; ATMs; adipose tissue macrophages; BAT; brown adipose tissue; CT; computed tomographic; DIO; high-fat-diet-induced obese; EGP; endogenous glucose production
Structural and enzyme kinetic studies of retrograded starch: Inhibition of α-amylase and consequences for intestinal digestion of starch
Keywords: GLUT2; plasma membrane glucose transporter; HAMS; high amylose maize starch; RHAMS; retrograded high amylose maize starch; SGLT; plasma membrane sodium dependent glucose transporters; Starch retrogradation; FTIR-ATR; MC-DSC; XRD; Amylase inhibition;
Osmolality of Orally Administered Solutions Influences Luminal Water Volume and Drug Absorption in Intestine
Keywords: water absorption; luminal water volume; gastrointestinal fluid volume; osmolality; drug absorption; FITC-dextran; atenolol; antipyrine; intestine; rat; AQP; aquaporin; FD-4; fluorescein isothiocyanate dextran 4000; GI; gastrointestinal; ka; first-order ab
Nuevos hipoglucemiantes orales y riesgo cardiovascular. Cruzando la frontera metabólica
Keywords: Diabetes mellitus tipo 2; Inhibidor del cotransportador de sodio-glucosa tipo 2; Enfermedad cardiovascular; Type 2 diabetes mellitus; Sodium-glucose cotransporter 2 inhibitor; Cardiovascular disease; DM2; diabetes mellitus tipo 2; HbA1c; glucohemoglobin
The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin
Keywords: DIO; diet-induced obese; DPP; dipeptidyl peptidase; FAS; fatty acid synthase; FPG; fasting plasma glucose; GDR; glucose disposal rate; HbA1c; glycated hemoglobin; HGP; hepatic glucose production; HPRT; hypoxanthine phosphoribosyltransferase; OGTT; oral gl
EGFR cooperates with glucose transporter SGLT1 to enable chromatin remodeling in response to ionizing radiation
Keywords: SGLT; EGFR; Ionizing radiation; Glucose uptake; ATP crisis;
Synthesis and biological evaluation of novel C-aryl d-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors
Keywords: Antidiabetics; SGLT; Glucofuranosides;
Neuroprotective effect through the cerebral sodium–glucose transporter on the development of ischemic damage in global ischemia
Keywords: Glucose transporter; Global ischemia; Hyperglycemia; SGLT; Neuroprotection
Berberine acutely inhibits the digestion of maltose in the intestine
Keywords: SGLT; Sodium-Dependent Glucose Cotransporter; GLUT; Glucose Transporter; ATP; Adenosine Triphosphate; ADP; Adenosine Diphosphate; PI; Inorganic Phosphate; ELISA; Enzyme Linked Immunosorbent assay; I.V.; Intravenous; I.P.; Intraperitoneal; GIR; Glucose Inf
Research ReportPost-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage through the cerebral sodium-glucose transporter
Keywords: Glucose transporter; Cerebral ischemia; Hyperglycemia; SGLT; Neuroprotection;
Exploration of SAR regarding glucose moiety in novel C-aryl glucoside inhibitors of SGLT2
Keywords: SGLT; Dapagliflozin; Thiazole; Glucose; Diabetes
Glucosides with cyclic diarylpolynoid as novel C-aryl glucoside SGLT2 inhibitors
Keywords: SGLT; Dapagliflozin; Diarylpolynoid; Glucoside; Diabetes
Glucose handling by the kidney
Keywords: GLUT; gluconeogenesis; renal glucose transport; SGLT;
A sodium glucose co-transporter (SGLT) for glucose transport into Crassostrea gigas vesicular cells: Impact of alimentation on its expression
Keywords: Crassostrea gigas; Glucose transport; Mollusc; Oyster; SGLT; Vesicular cells
Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents
Keywords: SGLT; Dapagliflozin; Ring-closing metathesis; Glucoside; Macrocycle;
Thiazolylmethyl ortho-substituted phenyl glucoside library as novel C-aryl glucoside SGLT2 inhibitors
Keywords: SGLT; Dapagliflozin; Thiazole; Glucoside; Diabetes
Novel thiophenyl C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents
Keywords: SGLT; Dapagliflozin; Thiophene; Glucoside; Diabetes
Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases
Keywords: ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con
C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization
Keywords: Glucose; Transporter; SGLT; SGLT2; C-Aryl glycoside; Diabetes; Inhibitor
Pyrimidinylmethylphenyl glucoside as novel C-aryl glucoside SGLT2 inhibitors
Keywords: SGLT; Dapagliflozin; Pyrimidine; Glucoside; Diabetes
Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: Pyridazinylmethylphenyl glucoside congeners
Keywords: SGLT; Dapagliflozin; Pyridazine; Glucoside; Diabetes;
Alstiphyllanines E–H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter
Keywords: Indole alkaloids; Alstonia macrophylla; Alstiphyllanines E–H; SGLT
Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: Possible reaction of cadmium with the zinc finger domain of Sp1
Keywords: Cd, cadmium; ChIP, chromatin immunoprecipitation; Cys, cysteine; EMSA, electrophoretic mobility shift assay; His, histidine; IR, infrared; rhSp1, recombinant human Sp1; SGLT, sodium-glucose cotransporter; Zn, zincCadmium; ChIP assay; Kidney; Sp1; SGLT; Zi
Transporters involved in glucose and water absorption in the Dysdercus peruvianus (Hemiptera: Pyrrhocoridae) anterior midgut
Keywords: Dysdercus peruvianus; GLUT; SGLT; Water absorption; Sugar absorption
ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors
Keywords: Diabetes; ortho-Substituted C-aryl glucosides; SGLT; Sodium-dependent glucose co-transporter; Urinary glucose; Blood glucose
Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: 1,3,4-Thiadiazolylmethylphenyl glucoside congeners
Keywords: SGLT; Dapagliflozin; Thiadiazole; Glucoside; Diabetes
Enhanced expressions of sodium–glucose cotransporters in the kidneys of diabetic Zucker rats
Keywords: Diabetes; Kidney; Glucose transporter; SGLT; NaPi-2; mRNA
O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors
Keywords: SGLT; Spiro; Glucosides
Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro
Keywords: Glutathione conjugates; MRP2; Hypoosmolarity; Glucose; SGLT
Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2
Keywords: Diabetes; Metabolism; Glucosidase; Metabolic diseases; NIDDM; C-Glucoside; C-Arylglucoside; SGLT; SGLT2; Sodium-dependent glucose transporter; Hyperglycemia; Glucosuria; Phlorizin; Dapagliflozin; Glucosidase