Keywords: One carbon metabolism; Cancer metabolism; Serine hydroxymethyltransferase; Isozymes; Enzyme inhibition; Pyrazolopyran scaffold; Pyridoxal 5â²-phosphate; PLP; serine hydroxymethyltransferase; SHMT; cytosolic SHMT; SHMT1; mitochondrial SHMT; SHMT2; Escheri
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Keywords: CH2THF; 5,10-methylene tetrahydrofolate; DCD; dCTP deaminase; DCD-DUT; bifunctional dCTP deaminase-dUTPase; DUT; dUTPase; DHF; dihydrofolate; DHFR; dihydrofolate reductase; DHFR-TS; bifunctional dihydrofolate reductase - thymidylate synthase; FAD; f
Keywords: ACSS; acetyl-CoA synthetase; ADI; arginine deiminase; AML; acute myeloid leukaemia; AMPK; AMP-activated protein kinase; ALL; acute lymphoblastic leukaemia; ASS; argininosuccinate synthase; BCAAs; branched-chain amino acids; BPTES; bis-2-(5-phenylacetamido
Structure and function of cytoplasmic serine hydroxymethyltransferase from Pichia pastoris
Keywords: SHMT; Crystal structure; Pichia expression system; Oligomerization; MS; SAXS;
Synthesis and characterization of cross linked enzyme aggregates of serine hydroxyl methyltransferase from Idiomerina leihiensis
Keywords: Pectin; SHMT; Formaldehyde; Cross-linked enzyme aggregates; Reusability metal ions;
Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors
Keywords: SHMT; Serine hydroxymethyltransferase; Ld; Leishmania donovani; PLP; Pyridoxal phosphate; THF; Tetrahydrofolate; TS; Thymidylate synthase; PDB; Protein Data Bank; NCBI; National Center for Biotechnology Information; DOPE; Discrete optimized protein energy
Folate and microRNA: Bidirectional interactions
Keywords: 1CM; One-carbon metabolism; 5-MTHF; methyltetrahydrofolate; Aβ; amyloid-β protein; APP; amyloid precursor protein; DHFR; dihydrofolate reductase; MTHFR; methylenetetrahydrofolate reductase; MTR; methionine synthase; NAFLD; Non-alcoholic fatty liver dise
TRAP and SRAP molecular marker based profiling of radiation induced mutants of sugarcane (Saccharum officinarum L.)
Keywords: AFLP; amplified fragment length polymorphism; AKTS; Akola Trombay sugarcane mutants; BRIT; Board of Radiation and Isotope Technology; CTAB; cetyl trimethyl ammonium bromide; FAOSTAT; the statistics division of Food and Agriculture Organization (FAO); GS;
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability
Keywords: MTHFD1; SHMT; TYMS; DHFR; Thymidylate; Folate; Lamin; DNA replication; Multi-enzyme complex; FOCM; folate-mediated one-carbon metabolism; MTHFD1; methylenetetrahydrofolate dehydrogenase 1; SHMT1; cytoplasmic serine hydroxymethyltransferase; TYMS; thymidyl
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
Keywords: SHMT; serine hydroxymethyltransferase; SHMT1; cytosolic SHMT; SHMT2; mitochondrial SHMT; 3BP; 3-bromopyruvate; PLP; pyridoxal 5â²-phosphate; H4PteGlu; tetrahydropteroylglutamate; Cancer metabolic reprogramming; Serine hydroxymethyltransferase; Isozymes;
A structural model for FOXRED1, an FAD-dependent oxidoreductase necessary for NADH: Ubiquinone oxidoreductase (complex I) assembly
Keywords: CPS; carbamoyl phosphate synthase; DAO; d-amino acid oxidase; DMGDH; dimethylglycine dehydrogenase; DMGO; dimethylglycine oxidase; FOXRED; FAD-dependent oxidoreductase; HADHA; hydroxyacyl dehydrogenase; MDH; malate dehydrogenase; MSOX; monomeric sarcosine
Proteomic analysis of the effects of gibberellin on increased fruit sink strength in Asian pear (Pyrus pyrifolia)
Keywords: ACA; acetyl-CoA C-acetyltransferase; ACX; medium chainacyl-coenzyme a oxidase peroxisomal; SHMT; serine hydroxymethyltransferase; MATS; -adenosylmethionine synthetase; FDH; formate dehydrogenase; OEE; oxygen-evolving enhancer protein; γCA; gamma carbonic
Metabolic flux analysis of the halophilic archaeon Haladaptatus paucihalophilus
Keywords: 13C-assisted metabolism analysis; Glycine biosynthesis; Halophilic archaea; Isoleucine biosynthesis; Lysine biosynthesis; SHMT; Serine hydroxymethyltransferase; TA; threonine aldolase; GCS; glycine cleavage system; TCA; tricarboxylic acid; THF; tetrahydro
MYC and metabolism on the path to cancer
Keywords: 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip
Structural stability of cold-adapted serine hydroxymethyltransferase, a tool for β-hydroxy-α-amino acid biosynthesis
Keywords: SHMT; serine hydroxymethyltransferase; PLP; pyridoxal-5â²-phosphate; H4PteGlu; tetrahydropteroylglutamate; piSHMT; SHMT from Psychromonas ingrahamii; ecSHMT; SHMT from Escherichia coli; Psychrophilic serine hydroxymethyltransferase; Protein stability; Co
Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool
Keywords: AD; Alzheimer disease; AIMs; amplification of inter-methylated sites; ALS; amyotrophic lateral sclerosis; ChIP; chromatin immunoprecipitation; CTH; cystathionine γ-lyase; CHARM; comprehensive high-throughput arrays for relative methylation; CBS; cystathi
A serine hydroxymethyltransferase from marine bacterium Shewanella algae: Isolation, purification, characterization and l-serine production
Keywords: TAIL-PCR; SHMT; Characterization; l-Serine enzymatic production; RP-HPLC
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Keywords: Pemetrexed; SHMT; Antifolate; Pleural mesotheliomaSHMT, serine hydroxymethyltransferase; THF, tetrahydrofolate; H4PteGlu, tetrahydropteroylglutamate; TS, thymidylate synthase; DHFR, dihydrofolate reductase; dTMP, 2′-deoxythymidine monophosphate
The serine hydroxymethyltransferase gene glyA in Corynebacterium glutamicum is controlled by GlyR
Keywords: glyA; SHMT; Stationary phase; Regulation; ArsR-type regulator
Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target
Keywords: SHMT; serine hydroxymethyltransferase; PfSHMT; Plasmodium falciparum serine hydroxymethyltransferase; Pv; P. vivax; dTMP; deoxythymidine 5â²-monophosphate; H4folate; (6RS)-tetrahydrofolate; CH2-H4folate; 5,10-methylenetetrahydrofolate; CH3-H4folate; 5-me
Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia
Keywords: ALL; acute lymphoblastic leukemia; CH2-THF; 5,10-methylenetetrahydrofolate; DDH; double distilled water; DHF; dihydrofolate; DHFR; dihydrofolate reductase; dTMP; deoxythymidine monophosphate; dTTP; deoxythymidine triphosphate; dUMP; deoxyuridine monophosp