Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation
Keywords: سیگنالینگ; Eph; Receptor; Kinase; Ephrin; Signaling;
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Protease-activated receptor 2 signaling upregulates angiogenic growth factors in renal cell carcinoma
Keywords: سیگنالینگ; PAR; Renal cell carcinoma; Angiogenesis; Signaling;
Functional roles for myosin 1c in cellular signaling pathways
Keywords: سیگنالینگ; Myosin; Signaling; Lipid raft;
Recent insights into the complexity of Tank-binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
Keywords: سیگنالینگ; Signaling; Kinase; Autophosphorylation; Activation; Localization; Substrate specificity;
IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages
Keywords: سیگنالینگ; MCP-1; IL-10; MAPK; TLR; Signaling;
An Infernal Trio: The chemokine CXCL12 and its receptors CXCR4 and CXCR7 in tumor biology
Keywords: سیگنالینگ; AP-1; activator protein 1; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; CREB; cAMP response element-binding; DPP; dipeptidyl peptidase; ECM; extracellular matrix; ELK-1; ETS-like transcription factor 1; ERK; extracellular-signal rela
TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells
Keywords: سیگنالینگ; TGF-β; transforming growth factor-β; IGF; insulin-like growth factor; IGFBP-3; IGF binding protein-3; TβR; TGF-β receptor; IGF1R; type I IGF receptor; TβRII; TGF-β type II receptor; TβRI; TGF-β type I receptor; R-Smads; receptor-activated Smads; M
Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: Involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase
Keywords: سیگنالینگ; Neutrophils; NADPH oxidase; p47phox; Rac2; ROS; Signaling;
Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: Role for reactive oxygen species-enhanced MEK/ERK activation
Keywords: سیگنالینگ; Eosinophils; cell death; signaling; 7AAD; 7-Aminoactinomycin D; DPI; Diphenyleneiodonium; DUSP; Dual-specificity phosphatase; EPX; Eosinophil peroxidase; ERK; Extracellular signal-regulated kinase; H2O2; Hydrogen peroxide; HRP; Horseradish peroxidase; JNK
Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells
Keywords: سیگنالینگ; T cell anergy; Type 1 diabetes; I-Ag7; Signaling;
Combined CpG and poly I:C stimulation of monocytes results in unique signaling activation not observed with the individual ligands
Keywords: سیگنالینگ; TLRs; Toll-like receptors; CpG; unmethylated CpG oligodeoxynucleotides; poly I:C; polyinosinic-polycytidylic acid; NO; nitric oxide; iNOS; inducible nitric oxide synthase; CREB; cAMP response element-binding protein; NFκB; nuclear factor κB; PRRs; pat
Rit subfamily small GTPases: Regulators in neuronal differentiation and survival
Keywords: سیگنالینگ; CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega
Combined inhibition of PI3K and activation of MAPK p38 signaling pathways trigger erythroid alternative splicing switch of 4.1R pre-mRNA in DMSO-induced erythroleukemia cells
Keywords: سیگنالینگ; BFU-E; burst forming unit-erythroid; DMSO; dimethylsulfoxide; EPO; erythropoietin; EPO-R; erythropoietin receptor; ERK; extracellular signal-regulated kinase; JAK2; Janus kinase-2; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein kin
PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells
Keywords: سیگنالینگ; signaling; actin cytoskeleton; photoreceptor outer segments; phagocytosis; retinal pigment epithelium;
Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells
Keywords: سیگنالینگ; TGFβ; transforming growth factor β; BMP; bone morphogenetic protein; BMPR2; BMP type II receptor; ACVR2; activin type II receptor; ECD; extracellular domain; AMHR2; anti-Müllerian hormone type II receptor; TGFBR2; TGFβ type II receptor; FSH; follicle-
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells
Keywords: سیگنالینگ; Anti-tumor properties; Breast and lung cancer cells; Vanadium-betaine-peroxido species; Signaling; Tumor suppression;
Improvement of stress tolerance in plants by genetic manipulation of mitogen-activated protein kinases
Keywords: سیگنالینگ; ABA; abscisic acid; ACC; 1-amino-cyclopropane-1-carboxylic acid; ACS6; ACC synthase 6; BAK1; BRI1-associated kinase 1; CTR1; constitutive triple response 1; EF-Tu; elongation factor thermo-unstable; ETI; effector-triggered immunity; ETR1; ethylene respons
p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris
Keywords: سیگنالینگ; AIH; autoimmune hepatitis; ANCA; anti-neutrophil cytoplasmic antibody; DSG; desmoglein; DUSP; dual specificity phosphatase; EAE; experimental autoimmune encephalomyelitis; GADD45; growth arrest and DNA damage inducible gene 45; GC; germinal center; HSP; h
Brucine, an indole alkaloid from Strychnos nux-vomica attenuates VEGF-induced angiogenesis via inhibiting VEGFR2 signaling pathway in vitro and in vivo
Keywords: سیگنالینگ; Vascular endothelial growth factor receptor-2; Signaling; Angiogenesis; Matrigel;
HYS-32, a novel analogue of combretastatin A-4, enhances connexin43 expression and gap junction intercellular communication in rat astrocytes
Keywords: سیگنالینگ; CA-4; combretastatin A-4; GJIC; gap junction intercellular communication; CHX; cycloheximide; LPS; lipopolysaccharide; PKC; protein kinase C; ERK; extracellular-regulated kinase; PKA; protein kinase A; MAPK; mitogen-activated protein kinase; JNK; c-Jun N-
Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2
Keywords: سیگنالینگ; DHEAS; Signaling; Erk1/2; CREB; ATF-1; Androgen receptor; Gnα11; Spermatogenic cells;
Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice
Keywords: سیگنالینگ; Neurodegeneration; Aging; Amyloid; Prion; Signaling;
Resistin decreases insulin-like growth factor I-induced steroid production and insulin-like growth factor I receptor signaling in human granulosa cells
Keywords: سیگنالینگ; Adipokines; growth factors; human ovary; signaling; steroidogenesis;
Podocyte-specific deletion of signal transducer and activator of transcription 3 attenuates nephrotoxic serum-induced glomerulonephritis
Keywords: سیگنالینگ; glomerulonephritis; glomerulus; podocyte; proliferation; signaling;
Stereospecific oxidation of calmodulin by methionine sulfoxide reductase A
Keywords: سیگنالینگ; DTPA; diethylenetriaminepentaacetic acid; MetO; methionine sulfoxide; MLCK; myosin light-chain kinase; MsrA; methionine sulfoxide reductase A; PDE1; phosphodiesterase 1; Calmodulin; Methionine oxidation; Methionine reduction; Methionine sulfoxide reductas
Integrin signaling in control of tumor growth and progression
Keywords: سیگنالینگ; Cancer; Integrins; Adhesion; Signaling; Metastasis
The role of Stat3 in glioblastoma multiforme
Keywords: سیگنالینگ; Glioblastoma multiforme; Signaling; Stat3; Therapy
Is phosphoproteomics ready for clinical research?
Keywords: سیگنالینگ; Phosphoproteomics; Mass spectrometry; Signaling
Targeting the Toll-like Receptor/Interleukin 1 Receptor Pathway in Human Diseases: Rational Design of MyD88 Inhibitors
Keywords: سیگنالینگ; Human diseases; MyD88; Signaling; Targeting; Toll-like receptor/interleukin 1 receptor
Role of PGC-1α in muscle function and aging
Keywords: سیگنالینگ; Aging; Mitochondria; Muscle; PGC-1α; Signaling
Determination of the physiological 2:2 TLR5:flagellin activation stoichiometry revealed by the activity of a fusion receptor
Keywords: سیگنالینگ; SF-TLR5, short flagellin linked to TLR5; SFΔD0, short flagellin with a deletion of the D0 domainToll-like receptor 5; Flagellin; Signaling; Innate immunity; Complex stoichiometry; Chimeric protein
Osteoarthritis year in review 2013: biology
Keywords: سیگنالینگ; Inflammation; Signaling; Growth factors; Bone; Cartilage; Meniscus; Synovium
A system for reconstructing B cell antigen receptor signaling in the mouse myeloma J558L cell line
Keywords: سیگنالینگ; CD19; CD45; Calcium signaling; B cell; Signaling; Synthetic biology
miRNAs in endothelial cell signaling: The endomiRNAs
Keywords: سیگنالینگ; miRNA; Development; Signaling; Endothelial cell; Angiogenesis
MKP3 eliminates depolarization-dependent neurotransmitter release through downregulation of L-type calcium channel Cav1.2 expression
Keywords: سیگنالینگ; Voltage-gated calcium channel; Gene expression; Map kinase; Signaling; Phosphatase; Exocytosis; pc12 cells
The role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development
Keywords: سیگنالینگ; Semaphorin3E; Plexin-D1; Semaphorins; Plexins; Neural development; Vascular development; Guidance; Signaling
Patients with acute pancreatitis complicated by organ dysfunction show abnormal peripheral blood polymorphonuclear leukocyte signaling
Keywords: سیگنالینگ; PMNL; Signaling; Immunosuppression; Severe acute pancreatitis;
Regulatory Roles of Metabolites in Cell Signaling Networks
Keywords: سیگنالینگ; Metabolite; Signaling; Modification; Binding; Epigenetics
Analysis of the cell wall integrity pathway of Ashbya gossypii
Keywords: سیگنالینگ; MAP kinase cascade; Signaling; Cell lysis; Osmotic stress; Riboflavin
A-kinase anchoring proteins: Molecular regulators of the cardiac stress response
Keywords: سیگنالینگ; A kinase anchoring protein (AKAP); Protein kinase A; Cardiac remodeling; Signaling; Cardiomyocyte
Fibrosing connective tissue disorders of the skin: Molecular similarities and distinctions
Keywords: سیگنالینگ; Fibrosis; Connective tissue; Signaling; miRNA
Epigenetic regulation of macrophage polarization and function
Keywords: سیگنالینگ; chromatin; epigenetics; macrophage; signaling; transcription
Insulin, IGF-I, and muscle MAPK pathway responses after sustained exercise and their contribution to growth and lipid metabolism regulation in gilthead sea bream
Keywords: سیگنالینگ; Fish; Exercise; Signaling; Metabolism; Growth
Activator or inhibitor? GSK-3 as a new drug target
Keywords: سیگنالینگ; GSK-3; Signaling; Regulation; Disease; Drug development
Involvement of PI3 kinase and MAP kinase in IGF-I and insulin-induced ovarian steroidogenesis in common carp Cyprinus carpio
Keywords: سیگنالینگ; IGF-I; b-Insulin; Signaling; Steroidogenesis; Theca–granulosa cells; Cyprinus carpio
UV-B exposure, ROS, and stress: inseparable companions or loosely linked associates?
Keywords: سیگنالینگ; UV-B; stress; ROS; antioxidant; acclimation; signaling
Regulation of cytoskeletal dynamics by phospholipase D and phosphatidic acid
Keywords: سیگنالینگ; actin; cytoskeleton; microtubules; phosphatidic acid; phospholipase D; signaling
Paradoxical antagonism of PACAP receptor signaling by VIP in Xenopus oocytes via the type-C natriuretic peptide receptor
Keywords: سیگنالینگ; Natriuretic peptide; Neuropeptide; Receptor; Signaling; cAMP; Xenopus
A test of the conspicuous–consumption model using subjective well-being data
Keywords: سیگنالینگ; D60; D12; D31Conspicuous consumption; Signaling; Subjective well-being
Preemptive bidding in takeover auctions with externality
Keywords: سیگنالینگ; G34; D44; C72Jump bidding; Preemptive bidding; Signaling; Externality; Takeover auction