دانلود مقالات ISI درباره RNA راهنما تنها + ترجمه فارسی

اشکال زدایی کد ژنتیکی: عدم تحرک غیر ویروسی در تحویل فن آوری های ویرایش ژنوم درمانی

Debugging the genetic code: Non-viral in vivo delivery of therapeutic genome editing technologies

Keywords: RNA راهنما تنها; Therapeutic genome editing; Non-viral delivery; Nuclease-mediated genome editing; Oligonucleotide-mediated genome editing; CRISPR/Cas9; Peptide nucleic acid; BBB; blood brain barrier; CMV; cell-derived membrane vesicle; CRISPR; Clustered Regularly Intersp

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

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Characterization of gamma-tubulin filaments in mammalian cells

Keywords: RNA راهنما تنها; γTuRC; γ-tubulin ring complex; γTuSC; γ-tubulin small complex; CDA; citral dimethyl acetal; DMF; dimethyl fumarate; DAPI; 4′,6′-diamidino-2-phenyindole, dihydrochloride; sgRNA; single guide RNA; rest; sgRNA-resistant; shRNA; short hairpin RNA; shr

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

The Implications of CRISPR-Cas9 Genome Editing for IR

Keywords: RNA راهنما تنها; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DSB; double-strand break; HDR; homology-directed repair; HR; homologous recombination; NHEJ; nonhomologous end-joining; PAM; protospacer-adjacent motif; sgRNA; single guide RNA;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Diagnosis and therapy with CRISPR advanced CRISPR based tools for point of care diagnostics and early therapies

Keywords: RNA راهنما تنها; CRISPR; clustered regularly interspaced short palindromic repeats; Cas; CRISPR-associated protein; crRNA; CRISPR RNA; SgRNA; single guide RNA; tracrRNA; trans-activating RNA; PAM; protospacer-adjacent motif; DSB; DNA double strand break; SHERLOCK; Specifi

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells

Keywords: RNA راهنما تنها; BrdU; bromodeoxyuridine; CBS; cystathionine-beta-synthase; CRISPR; clustered regularly interspaced short palindromic repeats; CSE; cystathionine-gamma-lyase; DMEM; dulbecco's modified eagle's medium; ERK; extracellular regulated protein kinase; FBS; f

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells

Keywords: RNA راهنما تنها; CHO cells; Chinese Hamster Ovary cells; CRISPR; clustered regularly interspaced short palindromic repeat; sgRNA; single guide RNA; ST3GAL; alpha-2,3-sialyltransferase; ST6GAL; alpha-2,6-sialyltransferase; EPO; erythropoietin; Fc; Fragment crystallizable;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

H2S protects lipopolysaccharide-induced inflammation by blocking NFκB transactivation in endothelial cells

Keywords: RNA راهنما تنها; H2S; Cystathionine gamma-lyase; LPS; Endothelial cells; Inflammation; NFκB; ChIP; chromatin immunoprecipitation; CRISPR; clustered regulatory interspersed short palindromic repeats; CSE; Cystathionine gamma-lyase; H2S; Hydrogen sulfide; HUVEC; Human umbi

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach

Keywords: RNA راهنما تنها; COPD; Chronic obstructive pulmonary disease; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated Protein 9 (Cas9); CSC; Cigarette smoke co

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation

Keywords: RNA راهنما تنها; BLI; bioluminescence imaging; BSA; bovine serum albumin; CTL; cytotoxic T lymphocytes; CRISPR/Cas; Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated nucleases; DEGs; differently expressed genes; DMEM; Dulbecco's modified Eagle's

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

SNORA21 - An Oncogenic Small Nucleolar RNA, with a Prognostic Biomarker Potential in Human Colorectal Cancer

Keywords: RNA راهنما تنها; CRC; colorectal cancer; ncRNAs; non-coding RNAs; miRNAs; microRNAs; lncRNAs; long non-coding RNAs; rRNAs; ribosomal RNAs; snoRNAs; small nucleolar RNAs; snoRNPs; small nucleolar ribosonucleoproteins; FFPE; formalin-fixed paraffin-embedded; NM; normal muco

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring the potential of genome editing CRISPR-Cas9 technology

Keywords: RNA راهنما تنها; Cas; CRISPR-associated proteins; cccDNA; covalently closed circular DNA; CCR5; C-C chemokine receptor type 5; CHO; Chinese hamster ovary; CRISPRs; clustered regularly interspaced short palindromic repeats; CRISPRa; CRISPR activation; CRISPRi; CRISPR inter

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2017 سفارش ترجمه

Controlling transcription in human pluripotent stem cells using CRISPR-effectors

Keywords: RNA راهنما تنها; CAG; hybrid of cytomegalovirus immediate early enhancer, chicken β-actin promoter and intron, rabbit β-globin splice acceptor; Cas; CRISPR-associated; CRISPR; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR-derived RNA; dCas9; n

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production

Keywords: RNA راهنما تنها; CRISPR; Clustered regularly interspaced short palindromic repeats; CRISPRi; Clustered regularly interspaced short palindromic repeats interference; MVA; mevalonate; sgRNA; single guide RNA; dCas9; inactive Cas9; IPP; isopentenyl diphosphate; DMAPP; dimeth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

lncRNA in the liver: Prospects for fundamental research and therapy by RNA interference

Keywords: RNA راهنما تنها; Long noncoding RNA (lncRNA); Delivery; siRNA; Liver; GalNAc conjugate; Lipid nanoparticle (LNP); Endosome escape; RNAi; siRNA; Hepatocellular carcinoma; ASGPR; asialoglycoprotein receptor; CRISPR-Cas; clustered regularly interspaced short palindromic re

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Advances in therapeutic CRISPR/Cas9 genome editing

Keywords: RNA راهنما تنها; Cas9; CRISPR-associated protein 9; cccDNA; covalently closed circular DNA; CCR5; chemokine receptor 5; CFTR; cystic fibrosis transmembrane conductance regulator; CRISPRs; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR RNA; Crygc;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention

Keywords: RNA راهنما تنها; OA; osteoarthritis; ECM; extracellular matrix; HA; hyaluronan; HAS2; hyaluronan synthase-2; RCS; rat chondrosarcoma; sgRNA; single guide RNA; sGAG; sulfated glycosaminoglycan; DMMB; dimethylmethylene blue; Hyaluronan; Hyaluronan synthase-2; Aggrecan; Chon

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Current status of potential applications of repurposed Cas9 for structural and functional genomics of plants

Keywords: RNA راهنما تنها; CRISPR; Crop improvement; dCas9; Epigenetics; Gene editing; Gene regulation; CRISPRa; CRISPR activation; CRISPR-Cas; Clustered Regularly Interspaced Short Palindromic Repeats - CRISPR associated proteins; CRISPRi; CRISPR interference; crRNA; CRISPR RNA; D

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Advancements in zebrafish applications for 21st century toxicology

Keywords: RNA راهنما تنها; CRISPR; Clustered, regularly interspaced, short palindromic repeats; Dpf; Days post fertilization; DSB; Double strand break; Hpf; Hours post fertilization; HSC; Hematopoietic stem cell; HTS; High-throughput screen; KO; Knockout; MO; Morpholino oligonucleo

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

A Genome-Wide CRISPR Library for High-Throughput Genetic Screening in Drosophila Cells

Keywords: RNA راهنما تنها; CRISPR/Cas9; Genome-wide library; Drosophila; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeat; HTS; high throughput sequencing; sgRNA; single guide RNA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Systematic analysis of CRISPR-Cas9 mismatch tolerance reveals low levels of off-target activity

Keywords: RNA راهنما تنها; CRISPR; clustered regularly interspaced palindromic repeats; Cas9; CRISPR associated protein 9; crRNA; CRISPR RNA; tracrRNA; trans-activating CRISPR RNA; PAM; protospacer adjacent motif; sgRNA; single guide RNA; NGS; next generation sequencing; PSC; pluri

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه