دانلود مقالات ISI درباره Sirt1 + ترجمه فارسی

Kale supplementation up-regulates HSP70 and suppresses cognitive decline in a mouse model of accelerated senescence

Keywords: Aging; Cognitive decline; Kale; HSP70; SAMP8; BHT; butyl hydroxytoluene; BSA; bovine serum albumin; DHA; docosahexaenoic acid; HSF1; heat shock transcription factor 1; HSP; heat shock protein; KJ; kale juice; 8-OHdG; 8-hydroxydeoxyguanosine; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway

Keywords: Ethanol; ALDH2; eNOS; SIRT1; 4-HNE; Endothelial senescence;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotection by ethanolic extract of Syzygium aromaticum in Alzheimer's disease like pathology via maintaining oxidative balance through SIRT1 pathway

Keywords: Syzygium aromaticum; Alzheimer's disease; SIRT1; Serum; SH-SY5Y;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-204-5p regulates 3T3-L1 preadipocyte proliferation, apoptosis and differentiation

Keywords: C/EBPα; CCAAT/enhancer-binding proteins; PPAR-γ; peroxisome proliferator activated receptor-γ coactivator; AP2; adipocyte fatty-acid binding protein 2; CDK4; cyclin dependent kinase 4; CDK2; cyclin dependent kinase 2; CDK5; cyclin dependent kinase 5; p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

SRT1720, a potential sensitizer for radiotherapy and cytotoxicity effects of NVB-BEZ235 in metastatic breast cancer cells

Keywords: TNBC; triple negative breast cancer; IL-6; interleukin 6; BC; breast cancer; PI3K; phosphatidylinositol 3-kinase; mTOR; Mammalian target of rapamycin; CSC; cancer stem cell; CRT; chemo-radio therapy; Breast cancer; Chemo-radiotherapy; Cancer stem cells; I

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Long non-coding RNA MALAT1 interacts with transcription factor Foxo1 to regulate SIRT1 transcription in high glucose-induced HK-2 cells injury

Keywords: HK-2 cells injury; MALAT1; SIRT1; Foxo1; Diabetic nephropathy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Sirt1 S-nitrosylation induces acetylation of HMGB1 in LPS-activated RAW264.7 cells and endotoxemic mice

Keywords: iNOS; SIRT1; Sepsis; Acetylation of HMGB1; S-nitrosyltaion of SIRT1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

A novel SIRT1 activator E6155 improves insulin sensitivity in type 2 diabetic KKAy mice

Keywords: SIRT1; AMPK; AKT; Glucose metabolism; Insulin sensitivity; Diabetes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Research reportPharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease

Keywords: Alzheimer's disease; D3T; Cognition; Oxidative stress; Hippocampal neurogenesis; Sirt1; Nrf2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

d-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions

Keywords: d-gal; d-galactose; LECs; lens epithelial cells; HCQ; hydroxychloroquine; ROS; reactive oxygen species; VADC; voltage dependent anion channel; mPTP; mitochondria permeability transition pore; MMP; mitochondrial membrane potential; NAC; N-acetylcysteine; G

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

IGFBP-3 plays an important role in senescence as an aging marker

Keywords: Senescence; IGFBP-3; SIRT1; Autophagy; H2O2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Paeonol alleviated acute alcohol-induced liver injury via SIRT1/Nrf2/NF-κB signaling pathway

Keywords: Paeonol; Alcoholic liver disease; Oxidative stress; Inflammation; SIRT1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

The reciprocal link between EVI1 and miRNAs in human malignancies

Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3′-UTR; 3′-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

SIRT1 suppresses high glucose and palmitate-induced osteoclast differentiation via deacetylating p66Shc

Keywords: SIRT1; Diabetes mellitus; Osteoclast differentiation; p66Shc; ROS; NF-κB;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway

Keywords: NAMPT inhibition; NAD salvage; FK866; APO866; SIRT1; SIRT2; p53; p21; BAX; Caspase; NMN; Chemotherapy; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential

Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia

Keywords: Stroke; Blood-brain barrier; Sirt1; Sirt3; Mitochondrial ROS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

One step ahead: miRNA-34 in colon cancer-future diagnostic and therapeutic tool?

Keywords: AOM; azoxymethane; APC; adenomatous polyposis coli; BTG-4; B-cell translocation gene; CAC; colitis associated cancer; CSCs; cancer stem cells; CRC; colorectal cancer; DSS; dextran sodium sulfate; GSK-3; glycogen synthase kinase-3; EMT; epithelial-mesenchy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy

Keywords: SIRT1; Gene expression; Depression; Electroconvulsive therapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Gallotannin derivatives from mango (Mangifera indica L.) suppress adipogenesis and increase thermogenesis in 3T3-L1 adipocytes in part through the AMPK pathway

Keywords: ATCC; American Type Culture Collection; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; C/EBPα; CCAAT/enhancer binding protein α; CPT1; carnitine palmitoyltransferase I; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; DMEM; Dulbecco's

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis

Keywords: SIRT1; AMPK; Osteoarthritis; Hyperhomocysteinemia; Chondrocytes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

SIRT1 expression regulates the transformation of resistant esophageal cancer cells via the epithelial-mesenchymal transition

Keywords: PTX; Paclitaxel; RI; resistance index; SIRT1; Resistant esophageal cells; Epithelial-mesenchymal transition; Cell migration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications

Keywords: Diabetic complications; ROS; Antioxidant; Sirt1; Nrf2; Aldose reductase inhibitor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Protection by different classes of dietary polyphenols against palmitic acid-induced steatosis, nitro-oxidative stress and endoplasmic reticulum stress in HepG2 hepatocytes

Keywords: Non-alcoholic fatty liver disease; Functional food polyphenols; Endoplasmic reticulum stress; Oxidative stress; Mitochondrial dysfunction; AMPK; AMP-activated protein kinase; ATP5G1; ATP synthase, mitochondrial Fo complex, subunit C1 (subunit 9); CCCP; ca

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway

Keywords: ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Long noncoding RNA maternally expressed gene 3 knockdown alleviates lipopolysaccharide-induced inflammatory injury by up-regulation of miR-203 in ATDC5 cells

Keywords: Osteoarthritis; Maternally expressed gene 3; microRNA-203; Sirt1; PI3K/AKT; NF-κB;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Qing Gan Zi Shen Tang alleviates adipose tissue dysfunction with up-regulation of SIRT1 in spontaneously hypertensive rat

Keywords: Qing Gan Zi Shen Tang; Spontaneously hypertensive rat; Epididymal white adipose tissue dysfunction; SIRT1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling

Keywords: HHcy; hyperhomocysteinemia; Hcy; homocysteine; LOX-1; lectin-like oxidized low density lipoprotein receptor-1; PKC; protein kinase C; SIRT1; sirtuin 1; CAD; coronary artery disease; SOD; superoxidase dismutase; GPx; glutathione peroxidase; and AMPK; AMP-a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Mounting evidence validates Ursolic Acid directly activates SIRT1: A powerful STAC which mimic endogenous activator of SIRT1

Keywords: Ursolic acid; SIRT1; Resveratrol; Sirt1 activating compounds;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Upregulation of SIRT1 contributes to the cardioprotective effect of Rutin against myocardial ischemia-reperfusion injury in rats

Keywords: MI/R; myocardial ischemia/reperfusion; SIRT1; silent information regulator 1; Nrf2; NF-E2-related factor 2; HO-1; heme oxygenase 1; NQO1; NAD(P)H:quinine oxidoreductase 1; LAD; left anterior descending; ROS; reactive oxygen species; ECG; electrocardiogram

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins

Keywords: AKT; protein kinase B; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; CUMS; chronic unpredictable mild stress; FST; forced swim test; GAP-43; growth-associated protein-43; GSK-3β; glycogen synthase kinase-3β; OFT;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis

Keywords: carnosol (PubChem CID:442009); resveratrol (PubChem CID:445154); DZNep; 3-Deazaneplanoci A; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CS; carnosol; CCl4; carbon tetrachloride; H3K27me3; catalyzes trimethylation of lysine 27 on histon

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene

Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury

Keywords: diabetic kidney disease; PGC1α; podocytes; SIRT1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Galangin's potential as a functional food ingredient

Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds

Keywords: AMPK; adenosine monophosphate-activated protein kinase; APAB; 2,2′-azo-bisamidinopropane; BSA; bovine serum albumin; CCL4; carbon tetrachloride; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; DTPA; diethylenetriaminepentaacetic acid

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

Keywords: NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro

Keywords: Chronic unpredictable mild stress; Cognitive impairment; Resveratrol; Sirt1; miR-134;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

SIRT1 and microRNAs: The role in breast, lung and prostate cancers

Keywords: SIR2; (Silent Information Regulator2); HDACs; (histone deacetylases); NAD +; (nicotinamide adenine dinucleotide); UTR; (untranslated region); pRb; (retinoblastoma protein); lnc RNA; (Long noncoding RNA); ERG; (ETS Related Gene); EMT; (epithelial to mesenc

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

MiR-138/SIRT1 axis is implicated in impaired learning and memory abilities of cerebral ischemia/reperfusion injured rats

Keywords: Cerebral ischemia/reperfusion injury; Bilateral common carotid occlusion; Hippocampus; Learning; Memory; Autophagy; SIRT1;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Promotion of SIRT1 protein degradation and lower SIRT1 gene expression via reactive oxygen species is involved in Sb-induced apoptosis in BEAS-2b cells

Keywords: Sb; antimony; SIRT1; silent mating type information regulation 2 homolog 1; COPD; chronic obstructive pulmonary disease; ROS; reactive oxygen species; TUNEL; terminal deoxynucleotidyl transferase-mediated nick end labelling; NAC; N-acetylcysteine; MAPKs;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Sirt1 alleviates LPS induced inflammation of periodontal ligament fibroblasts via downregulation of TLR4

Keywords: Sirt1; Sirtuin1; PLF; periodontal ligament fibroblasts; LPS; lipopolysaccharide; IL-1α; interleukin-1α; IL-6; interleukin-6; IL-8; interleukin-8; TNF-α; tumor necrosis factor-α; TLR4; toll-like receptor 4; JNK/NF-κB; c-Jun N-terminal kinase/nuclear f

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of a novel antisense long non-coding RNA PLA2G16-AS that regulates the expression of PLA2G16 in pigs

Keywords: NATs; natural antisense transcripts; PLA2G16; phospholipase A2 group XVI; lncRNAs; long non-coding RNAs; VIM; vimentin; VIM-AS1; VIM antisense transcript1; BACE1; β-site APP-cleaving enzyme 1; BACE1-AS; BACE1 antisense transcript; PLA2G16-AS; PLA2G16 ant

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

The change of nuclear LC3 distribution in acute myeloid leukemia cells

Keywords: Acute myeloid leukemia; Nuclear LC3; Autophagy; Sirt1; DOR;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway

Keywords: Tan C; Tanshindiol C; oxLDL; oxidized low-density lipoprotein; Nrf2; NF-E2-related factor 2; ARE; antioxidant-response element; Sirt1; Sirtuin 1; Prdx1; peroxiredoxin 1; ABCA1; adenosine triphosphate-binding cassette (ABC) transporter A1; ABCG1; ATP-bindi

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Impairment of energy sensors, SIRT1 and AMPK, in lipid induced inflamed adipocyte is regulated by Fetuin A

Keywords: Fetuin A; SIRT1; AMPK; PGC1α; Adipocyte; Energy homeostasis;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

High glucose up-regulates microRNA-34a-5p to aggravate fibrosis by targeting SIRT1 in HK-2 cells

Keywords: MicroRNA-34a-5p; SIRT1; HK-2 cell; Tubulointerstitial fibrosis; Diabetic nephropathy;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

The ADRA2A rs553668 variant is associated with type 2 diabetes and five variants were associated at nominal significance levels in a population-based case-control study from Mexico City

Keywords: ADRA2A; Alpha-2a-adrenergic receptor; BMI; Body mass index; CHO; Cholesterol; DNA; Deoxyribonucleic acid; ENSANUT; National Survey of Health and Nutrition; FPG; Fasting plasma glucose; GWAS; Genome wide association study; HDL-C; Cholesterol high density l

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis

Keywords: ApoB; apolipoprotein B; CBDL; common bile duct ligation; CCl4; carbon tetrachloride; CPT1; peroxisome carnitine palmitoyl transferase 1; CREBH; cAMP responsive element binding protein H; DNL; de novo lipogenesis; ECM; extracellular matrix; ER; endoplasmic

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Sirtuin‑1 protects hair follicle stem cells from TNFα-mediated inflammatory stress via activating the MAPK-ERK-Mfn2 pathway

Keywords: Sirt1; Hair follicle stem cell; The inflammatory microenvironment; Mitochondrial damage;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه