Keywords: Axonal transport; Transcytosis; SNAP-25; Motoneurons; Spasticity; Dystonia;
مقالات ISI (ترجمه نشده)
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Keywords: BoNT-A; Botulinum neurotoxin serotype A; BoNT-C; Botulinum neurotoxin serotype C; EPPs; endplate potentials; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MCA; maleimidohexanoic acid (maleimidocaproic acid); PT; pre-tetanus; PTP; post-tetanic
Keywords: GFAP; (glial fibrillar acid protein); SNAP-25; (synaptosomal-associated protein 25); Caffeine; Adenosine; Aging; Anxiety; Synaptic proteins;
Keywords: Ischemia; Brain preconditioning; Neuroprotection; Functional food; Synaptogenesis; Neurogenesis; ALA; alpha-linolenic acid; ANSES; Agence Nationale pour la Sécurité et la Santé; BDNF; brain derived neurotrophic factor; CVD; cardiovascular diseases; DHA
Keywords: Lead exposure; Neurotoxicity; Lipid peroxide; Apoptosis; TNFα; PSD-95; SNAP-25; BDNF; TrkB; VAChT
Keywords: Schizophrenia; Synapse; Olfactory bulb; Synaptophysin; SNAP-25; PSD-95;
Keywords: Auditory pathway; Inner hair cells; Ribbon synapse; Endbulb of Held; Calyx of Held; Synaptopathy; AMPA; Alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate; ATD; Action potential transmission delay; AVCN; Anteroventral cochlear nucleus; CAPS; Ca2+-depen
Keywords: Electrochemical impedance spectroscopy; Cyclic voltammetry; Botulinum neurotoxin; SNAP-25
Keywords: AMPA receptors; methylphenidate; NMDA receptors; prefrontal cortex; SNAP-25; stress;
Keywords: Botulinum neurotoxin; SNARE complex; Neuromuscular junction; Mechanism of action; Synaptic transmission; SNAP-25;
Keywords: In vivo microdialysis; Antidepressant; Basolateral amygdala; Central amygdala; vGLUT2; SNAP-25;
ERK1/2 inhibition increases dopamine release from differentiated PC12 cells
Keywords: PC12 cells; Dopamine; ERK1/2; U0126; PKG; PKA; Synapsin I; SNAP-25;
APOE ε4 is associated with higher levels of CSF SNAP-25 in prodromal Alzheimer's disease
Keywords: APOE ε4; Alzheimer's disease; Mild cognitive impairment; SNAP-25; Synaptic function;
The in vitro detection of botulinum neurotoxin-cleaved endogenous VAMP is epitope-dependent
Keywords: AraC; cytosine β-d-arabinofuranoside; BoNT; botulinum neurotoxin; DIV; days in vitro; ELISA; enzyme-linked immunosorbent assay; FBS; foetal bovine serum; HBSS; Hank's Balanced Salt Solution; PBS; phosphate buffered saline; PLO; poly-l-ornithine; RabMAb;
Early experimental results of using a novel delivery carrier, hyaluronan-phosphatidylethanolamine (HA-PE), which may allow simple bladder instillation of botulinum toxin A as effectively as direct detrusor muscle injection
Keywords: Botulinum toxin A; Detrusor overactivity; Modulated carrier; Neurogenic bladder; Bladder instillations; SNAP-25; BTX-A; Botulinum Toxin A; HA-PE; Hyaluronan-phosphatidylethanolamine; SNAP-25; Synaptosome associated protein 25; DO; Detrusor Overactivity; H
The impact of SNAP25 on brain functional connectivity density and working memory in ADHD
Keywords: SNAP-25; Working memory; Functional connectivity density; ADHD;
A SNAP-25 cleaving chimera of botulinum neurotoxin /A and /E prevents TNF뱉induced elevation of the activities of native TRP channels on early postnatal rat dorsal root ganglion neurons
Keywords: Botulinum neurotoxin; TNFα; TRPV1; TRPA1; SNAP-25;
Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress
Keywords: Prenatal stress; Depression; SNARE protein; vGluT1; ADHD; attention deficit hyperactivity disorder; CSPα; cysteine-string protein-α; EAAT; excitatory amino acid transporter; EPM; elevated plus maze; FST; forced swimming test; Munc-18; mammalian uncoordi
Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits
Keywords: Dendritic inhibition; Presynaptic inhibition; Network activity; Electron microscopy; Synaptic plasticity; Ion channels; BC; basket cell; CA; cornu ammonis; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cAMP; cyclic adenosine monophosphate; Cav chan
Molecular characterization and gene expression of synaptosome-associated protein-25 (SNAP-25) in the brain during both seaward and homeward migrations of chum salmon Oncorhynchus keta
Keywords: Neurotransmission; Olfactory imprinting; Salmon; Migration; Pre-synaptic exocytosis; SNAP-25; Teleostei;
New mechanism underlying IL-31-induced atopic dermatitis
Keywords: Atopic dermatitis; pruritogens; brain-derived natriuretic peptide; pruritus; skin; dorsal root ganglion; keratinocytes; dendritic cells; soluble N-ethylmaleimide-sensitive factor activating protein receptors; AD; Atopic dermatitis; BNP; Brain-derived na
An in vitro cell-based potency assay for pharmaceutical type A botulinum antitoxins
Keywords: BoNT; botulinum neurotoxin; SNAREs; soluble N-ethylmaleimide-sensitive factor attachment protein receptors; SNAP-25; 25 kDa synaptosomal associated protein; WHO; World Health Organization; MsLD50; mouse 50% lethal dose; IIBR; Israel Institute for Biologic
Immunohistochemical localization of SNARE core proteins in intrapulpal and intradentinal nerve fibers of rat molar teeth
Keywords: Syntaxin-1; SNAP-25; VAMP-2; Intrapulpal nerve; Intradentinal nerve; Exocytosis;
Localization of Rab3A-binding site on C2A domain of synaptotagmin I to reveal its regulatory mechanism
Keywords: SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; SNARE; soluble N-ethylmaleimide-sensitive factor attachment proteins receptor; SNAP-25; Synaptosomal-associated protein 25; Syt I; synaptotagmin I; C2A; C2A domain of Syt I; C2B; C2âB
A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A
Keywords: BoNTs; botulinum neurotoxins; BoNT/A; botulinum neurotoxin serotype A; HC; heavy chain; LC; light chain; SNARE; soluble N-ethylmaleimide-sensitive factor attachment protein receptor; SNAP-25; 25Â kDa synaptosomal-associated protein; BIG-IV; Botulism Immun
Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency
Keywords: BoNT/A; botulinum neurotoxin A; SNAP-25; synaptosomal protein of molecular mass 25Â kDa; EB; embryoid bodies; ESDN; embryonic stem cell-derived neurons; mESC; mouse embryonic stem cells; HC; heavy chain; LC; light chain; LHn/A; recombinant endopeptidase f
Antinociceptive effect of botulinum toxin A involves alterations in AMPA receptor expression and glutamate release in spinal dorsal horn neurons
Keywords: botulinum toxin A; retrograde transport; SNAP-25; AMPA receptor; glutamate release; dorsal horn neurons;
Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A
Keywords: Botulism; Botulinum toxin; Botulinum neurotoxin; Mercaptoacetamide; Metalloprotease inhibitor; SNAP-25; SNARE protein; X-ray crystallography; ADME; absorption, distribution, metabolism and excretion; BAT®; heptavalent botulism antitoxin; BHSAI; Biotechno
Disruption of glutamate neurotransmitter transmission is modulated by SNAP-25 in benzo[a]pyrene-induced neurotoxic effects
Keywords: Benzo[a]pyrene; Learning and memory; Glutamate; SNAP-25;
Lipoic acid prevents acrylamide-induced neurotoxicity in CD-1 mice and BV2 microglial cells via maintaining redox homeostasis
Keywords: ACR; acrylamide; LA; lipoic acid; CNS; central nervous system; GSH; glutathione; MPO; myeloperoxidase; BDNF; brain derived neurotrophic factor; NGF; nerve growth factor; NT-3; neurotrophin-3; GFAP; glial fibrillary acidic protein; NSF; N-ethylmaleimide se
Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice
Keywords: ACh; acetylcholine; BiVs; Botulinum neurotoxin-A-induced varicosities; BoNT-A; botulinum neurotoxin-A; BoNT-B; botulinum neurotoxin-B; BoNT-C; botulinum neurotoxin-C; ChAT; choline acetyltransferase; CPu; caudate-putamen; DA; dopamine; hemi-PD; hemisparki
Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease
Keywords: 5-HT; 5-hydroxytryptamine; 7,8-DHF; 7,8-dihydroxyflavone; ACh; acetylcholine; AD; adenosine; ADL; activities of daily living; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; 5â²AMP-activated protein kinase; BDNF; brain-derived neurotro
Research ReportIntrastriatal injection of botulinum neurotoxin-A is not cytotoxic in rat brain - A histological and stereological analysis
Keywords: Ach; acetylcholine; BiVs; BoNT-A-induced varicosities; BoNT-A; botulinum neurotoxin-A; ChAT; choline acetyltransferase; CPu; caudatus putamen complex; ir; Immunoreactive; L-DOPA; L-3,4-Dihydroxyphenylalanine; PD; Parkinson׳s disease; SNAP-25; synaptosoma
Select putative neurodevelopmental toxins modify SNAP-25 expression in primary cultures of rat cerebellar granule cells
Keywords: Environmental toxins; SNAP-25; mRNA & protein expression; Neurodevelopmental disability;
Different attentional abilities among inbred mice strains using virtual object recognition task (VORT): SNAP25+/− mice as a model of attentional deficit
Keywords: Inbred mice; Visual attention; Novel object recognition; Visual object recognition; Shapes movement; SNAP-25
Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1
Keywords: C; Control; EGFP; Enhanced Green Fluorescent protein; ESI-05; 4-Methylphenyl-2, 4, 6-trimethylphenylsulfone; F-actin; Filamentous Actin; GLP-1; Glucagon-like peptide 1; GSIS; Glucose-stimulated insulin secretion; HG; High-glucose; NPY; Neuropeptide Y; RFP
Snapin mediates insulin secretory granule docking, but not trans-SNARE complex formation
Keywords: Exocytosis; SNAP-25; Secretory granule tethering;
Palmitoylation in Alzheimerâ¿¿s disease and other neurodegenerative diseases
Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer⿿s disease; ADAM17; a disintegrin and metalloproteinase 17; AICD; APP intracellular domain; AKAP79; A-kinase anchoring protein 79; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APP; amy
ReviewBotulinum neurotoxin type A: Actions beyond SNAP-25?
Keywords: BoNT/A; botulinum neurotoxin type A; HC; heavy chain; LC; light chain; SNAP-25; synaptosomal-associated protein of 25Â kDa; SV2; synaptic vesicle protein 2; SNARE; soluble N-ethylmaleimide-sensitive factor attachment protein receptor; VAMP; vesicle-associ
Cysteine string protein (CSP) and its role in preventing neurodegeneration
Keywords: ANCL; adult onset neuronal ceroid lipofuscinosis; CREB; cAMP response element binding protein; CSP; cysteine string protein; GABA; gamma-amino butyric acid; SGT; small glutamine-rich tetratricopeptide repeat-containing protein; SNAP-25; synaptosome-associ
Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A
Keywords: Botulinum neurotoxin; BoNT/A-LC inhibitor; SNAPtide; SNAP-25; HTP in silico screening;
A graphene oxide based fluorescence resonance energy transfer (FRET) biosensor for ultrasensitive detection of botulinum neurotoxin A (BoNT/A) enzymatic activity
Keywords: Graphene oxide (GO); Botulinum neurotoxins (BoNTs); SNAP-25; Green fluorescence protein (GFP); Optical detection
Sphingomyelin derivatives increase the frequency of microvesicle and granule fusion in chromaffin cells
Keywords: AA; arachidonic acid; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MSD; Mean Square Displacement; SMase; sphingomyelinase; SNAP-25; synaptosomal-associated protein of 25Â K
Tomosyn is a novel Akt substrate mediating insulin-dependent GLUT4 exocytosis
Keywords: GLUT4; glucose transporter 4; EGFP; enhanced green fluorescence protein; GST; glutathione S-transferase; PKA; protein kinase A; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; SNARE; soluble NSF-attachment protein receptors; SNAP-25;
Interactions of a potent cyclic peptide inhibitor with the light chain of botulinum neurotoxin A: Insights from X-ray crystallography
Keywords: BoNT; botulinum neurotoxin; Balc; botulinum neurotoxin A light chain; Balc424; Balc truncated at residue 424; Balc448; full-length Balc; CPI-1; cyclic peptide inhibitor-1; CPI-2; cyclic peptide inhibitor-2; DAB; 2,4-diaminobutanoic acid; FRET; Förster re
Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals
Keywords: ANCOVA; analysis of covariance; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; CA; Cornu Ammonis; cELISA; capture ELISA; dELISA; direct ELISA; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; GABA; gamma-aminobutyric aci
The neuromuscular activity of Bothriopsis bilineata smaragdina (forest viper) venom and its toxin Bbil-TX (Asp49 phospholipase A2) on isolated mouse nerve-muscle preparations
Keywords: Calcium mobilization; Ion channel; Neuromuscular blockade; Snake venom phospholipase A2; Presynaptic activity; Quantal content; SNAP-25; Synaptophysin
Development of a fusion protein SNVP as substrate for assaying multi-serotype botulinum neurotoxins
Keywords: Botulinum neurotoxin; SNAP-25; VAMP-2; Biological assay
Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain
Keywords: Botulinum neurotoxin; SNARE; SNAP-25; Protease inhibitor; Zinc-dependent metalloprotease; Hydroxamic acid; Carbamate prodrug;
The purinergic neurotransmitter revisited: A single substance or multiple players?
Keywords: ATP; NAD; ADP-ribose; Adenosine; Purinergic neurotransmission; Nervous system; ACh; acetylcholine; ADP; adenosine 5â²-diphosphate; ADPR; adenosine 5â²-diphosphate ribose; AMP; adenosine 5â²-monophosphate; ApnA; diadenosine polyphosphates; ATP; adenosin