Keywords: سیکلاس گوانیلات حل کننده; Monocrotaline; Nitric oxide; Pulmonary hypertension; Soluble guanylate cyclase;
مقالات ISI سیکلاس گوانیلات حل کننده (ترجمه نشده)
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Keywords: سیکلاس گوانیلات حل کننده; AA; arachidonic acid; AM; acetoxymethyl; CalDAG-GEFI; calcium- and DAG-regulated guanine nucleotide exchange factor 1; COX; cyclooxygenase; DAG; diacylglycerol; FITC; fluorescein isothiocyanate; FSC; forward scatter; GS; stimulatory G-protein; IP3; inosit
Keywords: سیکلاس گوانیلات حل کننده; Isolated aorta; Nitro compounds; Soluble guanylate cyclase; Vasorelaxant effects;
Keywords: سیکلاس گوانیلات حل کننده; Soluble guanylate cyclase; Nitric oxide; Heme cofactor; Allosteric activation;
Keywords: سیکلاس گوانیلات حل کننده; Pulmonary arterial hypertension; Endothelin receptor antagonist; Prostacyclin; Nitric oxide; Dose titration; Specialty pharmacy; ERA; endothelin receptor antagonist; ET-1; endothelin 1; PAH; pulmonary arterial hypertension; PAWP; pulmonary artery wedge pr
Keywords: سیکلاس گوانیلات حل کننده; AAD; allergic airways disease; AECs; amnion epithelial cells; AHF; acute heat failure; AHR; airway hyperresponsiveness; Ang II; angiotensin II; AT2; angiotensin type 2 receptor; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; ERK; extrac
Keywords: سیکلاس گوانیلات حل کننده; NO; nitric oxide; SNP; sodium nitroprusside; TNG; nitroglycerine; SHR; spontaneously hypertensive rats; TERPY; [Ru(terpy)(bdq)NO]3+; Eâ; endothelium-denuded; E+; endothelium-intact; 2K; sham-operated rats; 2K-1C; two-kidney one-clip, renal hypertensive
Keywords: سیکلاس گوانیلات حل کننده; Soluble guanylate cyclase; Cyclic guanosine monophosphate;
Keywords: سیکلاس گوانیلات حل کننده; Biotin; Soluble guanylate cyclase; Cgmp; Protein kinase G; Multiple sclerosis; Schwann cells; Neurotrophic factors; Alzheimers disease; Beta-amyloid; Phosphodiesterase-5;
Keywords: سیکلاس گوانیلات حل کننده; AS; Angeli's salt; AST; aspartate aminotransferase; ALT; alanine transaminase; BALF; bronchoalveolar lavage fluid; CGRP; calcitonin gene-related peptide; COX-2; cyclooxygenase-2; CFU; colony-forming unity; cGMP; cyclic guanosine monophosphate; PKG; cGMP-d
Keywords: سیکلاس گوانیلات حل کننده; PH; pulmonary hypertension; LHD; left heart disease; CHF; chronic heart failure; LV; left ventricular; RV; right ventricular; NO; nitric oxide; sGC; soluble guanylate cyclase; PDE; phosphodiesterase; cGMP; cyclic guanosine monophosphate; TAC; transverse a
Keywords: سیکلاس گوانیلات حل کننده; ANOVA; analysis of variance; AP; anteroposterior; BSA; bovine serum albumin; CNS; central nervous system; EPM; elevated plus maze; HPA; hypothalamic-pituitary-adrenal; IHC; immunohistochemistry; IL; infralimbic; MPFC; medial prefrontal cortex; NF-κB;
Keywords: سیکلاس گوانیلات حل کننده; heart transplantation; ischemia/reperfusion; soluble guanylate cyclase; soluble guanylate cyclase activation; cinaciguat; nitric oxide;
Keywords: سیکلاس گوانیلات حل کننده; 6WMD; 6-min walk distance; 6MWT; 6-min walk test; cGMP; cyclic guanosine monophosphate; CTD; connective tissue disease; ERA; endothelin receptor antagonist; ET-1; endothelin-1; HRQoL; health-related quality of life; MCS; mental component summary; MID; min
Keywords: سیکلاس گوانیلات حل کننده; Surface plasmon resonance; Biophysical techniques; Enzyme activators; Soluble guanylate cyclase; Nitric oxide;
Keywords: سیکلاس گوانیلات حل کننده; S1P; sphingosine-1-phosphate; HDL-S1P; HDL-bound S1P; albumin-S1P; albumin-bound S1P; AKT; protein kinase B; SPHK; sphingosine kinase; PI3K; phosphatidylinositol 3-kinase; S1PR1-3; S1P receptor 1-3; RAC-1; ras-related C3 botulinum toxin substrate 1;
Keywords: سیکلاس گوانیلات حل کننده; 3-NT; 3-nitrotyrosine; ADMA; asymmetric dimethyl arginine; Akt; protein kinase B; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; BH2; dihydrobiopterin; BH4; tetrahydrobiopterin; BMR; basal metabolic rate; Cav-1; caveolin-1; CCK; cholecysto
Keywords: سیکلاس گوانیلات حل کننده; adverse event; meta-analysis; pharmacovigilance; phosphodiesterase 5 inhibitors; soluble guanylate cyclase stimulators; ADE; adverse drug event; ADR; adverse drug reaction; cGMP; cyclic guanosine monophosphate; GRADE; Grading of Recommendation Assessment,
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
Keywords: سیکلاس گوانیلات حل کننده; Formaldehyde; Thoracic aorta ring; Vascular tension; Ion channels; Signal pathway; 4-AP; 4-aminopyridine; ACh; acetylcholine; l-NAME; NG-nitro-l-arginine methyl ester; ACE; angiotensin-converting enzyme; VSMCs; vascular smooth muscle cells; BKCa; big-cond
The dichotomous role of H2S in cancer cell biology? Déjà vu all over again
Keywords: سیکلاس گوانیلات حل کننده; 1400 W; N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide; 3-MP; 3-Mercaptopyruvate; 3-MST; 3-Mercaptopyruvate sulfurtransferase; ADT-OH; 5-(4-hydroxyphenyl)-3H-1, 2-dithiole-3-thione; AG; Aminoguanidine; AOAA; Aminooxyacetic acid; CAT; Cysteine aminotra
Oral administration of Zuccagnia punctata extract improves lipid profile, reduces oxidative stress and prevents vascular dysfunction in hypercholesterolemic rabbits
Keywords: سیکلاس گوانیلات حل کننده; High cholesterol diet; Zuccagnia punctata; Flavonoids; Endothelial function; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ACE; angiotensin converting enzyme; BW; body weight; CD; control diet; COX; cyclooxygenase; CRC; concentration res
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets
Keywords: سیکلاس گوانیلات حل کننده; Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple
A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H2O and -SNO intermolecular stabilization chemistry
Keywords: سیکلاس گوانیلات حل کننده; Cap; captopril; CapNO; S-Nitrosocaptopril; CapNO·H2O; S-Nitrosocaptopril monohydrate; NO; nitric oxide; ACEI; angiotensin-converting enzyme inhibitor; -SH; sulfhydryl; -SNO; S-nitroso; RSNO; S-Nitrosothiol or thionitrite; sGC; soluble Guanylate Cycla
Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides
Keywords: سیکلاس گوانیلات حل کننده; Coronary circulation; Endothelium; Nitric oxide; Ischemia; Oxidant stress; 2'-P-(c)ADPR; 2â²-phospho (cyclic) adenosine diphosphate ribose; BH2; Dihydrobiopterin; BH4; Tetrahydrobiopterin; BSA; Bovine serum albumin; CF; Coronary flow; cGMP; Cyclic guan
RISE-SSc: Riociguat in diffuse cutaneous systemic sclerosis
Keywords: سیکلاس گوانیلات حل کننده; Systemic sclerosis; Riociguat; Soluble guanylate cyclase; Fibrosis;
Rationale and study design of RESPITE: An open-label, phase 3b study of riociguat in patients with pulmonary arterial hypertension who demonstrate an insufficient response to treatment with phosphodiesterase-5 inhibitors
Keywords: سیکلاس گوانیلات حل کننده; Pulmonary arterial hypertension; sGC stimulator; Soluble guanylate cyclase; Riociguat;
The chemical biology of HNO signaling
Keywords: سیکلاس گوانیلات حل کننده; Nitroxyl; Azanone; Thiols; Nitrogen oxides; RSSH; hydropersulfides; DTT; dithiothreitol; GPx; glutathione peroxidase; BDE; bond dissociation energy; NHE; normal hydrogen electrode; metmyoglobin; MbFe3+; methemoglobin; HbFe3+; ferrous myoglobin; MbFe2+; sG
Erectile Dysfunction in Heme-Deficient Nitric Oxide-Unresponsive Soluble Guanylate Cyclase Knock-In Mice
Keywords: سیکلاس گوانیلات حل کننده; Soluble Guanylate Cyclase; Apo-sGC; Erectile Dysfunction; Oxidative Stress; Soluble Guanylate Cyclase Activators; Soluble Guanylate Cyclase Stimulators;
Riociguat: Mode of Action and Clinical Development in Pulmonary Hypertension
Keywords: سیکلاس گوانیلات حل کننده; chronic thromboembolic pulmonary hypertension; pulmonary arterial hypertension; sGC stimulator; 6MWD; 6-minute walking distance; ADMA; asymmetric dimethylarginine; AE; adverse event; BH4; tetrahydrobiopterin; BMPR-2; bone morphogenetic protein receptor-2;
Angiotensin II AT2 receptors regulate NGF-mediated neurite outgrowth via the NO-cGMP pathway
Keywords: سیکلاس گوانیلات حل کننده; Angiotensin II; Nerve growth factor; Angiotensin II type 2 receptor; NO-cGMP; AKT; protein kinase B; AT1; angiotensin II type 1; AT2; angiotensin II type 2; CGRP; calcitonin gene-related peptide; cGMP; cyclic guanosine monophosphate; DMEM; Dulbecco's-modi
Nitrosopersulfide (SSNOâ) targets the Keap-1/Nrf2 redox system
Keywords: سیکلاس گوانیلات حل کننده; Hmox1; heme oxygenase-1; Keap-1; Kelch-like ECH-associated protein; SSNOâ; nitrosopersulfide; Nrf2; nuclear factor (erythroid-derived 2)-like 2; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; NO and H2S cross talk; Nitroxyl; Nitrosopersulfide;
TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats
Keywords: سیکلاس گوانیلات حل کننده; TRPV3; Carvacrol; Uterus; Radial artery; Pregnancy; TRPV3; transient receptor potential vanilloid type-3 channel; IHC; immunohistochemistry; NO; nitric oxide; NOS; nitric oxide synthase; sGC; soluble guanylate cyclase; PKG; cGMP-dependent protein kinase;
The versatile ruthenium(II/III) tetraazamacrocycle complexes and their nitrosyl derivatives
Keywords: سیکلاس گوانیلات حل کننده; acn; acetonitrile; 4-acpy; pyridine-4-acetyl; acv; (acyclovir), 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one); am(m)ine; ammine, amine, and/or tetraazamacrocycle; ampy; 2-aminomethylpyridine; [15]aneN4; 1,4,8,12-tetraazacyclopentadecane;
The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice – Involvement of the soluble guanylate cyclase/KATP pathway
Keywords: سیکلاس گوانیلات حل کننده; Gastric defense; NSAIDs; Ethanol; Nitric oxide donor; Soluble guanylate cyclase; ATP-sensitive K+ channels
Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus
Keywords: سیکلاس گوانیلات حل کننده; Nitric oxide; μ-Opioid receptor; Locus coeruleus; Cyclic guanosine monophosphate; Reactive oxygen species; Slice; Firing; A 350619; 3-[2-[(4-chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride; aCSF; artificial cerebrospinal f
The sGC activator inhibits the proliferation and migration, promotes the apoptosis of human pulmonary arterial smooth muscle cells via the up regulation of plasminogen activator inhibitor-2
Keywords: سیکلاس گوانیلات حل کننده; Soluble guanylate cyclase; Pulmonary arterial smooth muscle cells; Plasminogen activator inhibitor-2; Proliferation; Apoptosis; Migration;
Differential involvement of signaling pathways in the regulation of growth hormone release by somatostatin and growth hormone-releasing hormone in orange-spotted grouper (Epinephelus coioides)
Keywords: سیکلاس گوانیلات حل کننده; GH; growth hormone; SRIF; somatotropin release-inhibitory factor; GHRH; GH-releasing hormone; PACAP; pituitary adenylate cyclase-activating peptide; DA; dopamine; GnRH; gonadotropin-releasing hormone; GPCR; G-protein-coupled receptor; SSTR; somatostatin r
Nitric oxide sets off an antioxidant response in adrenal cells: Involvement of sGC and Nrf2 in HO-1 induction
Keywords: سیکلاس گوانیلات حل کننده; Nitric oxide; Heme oxygenase 1; Nuclear factor-erythroid 2-related factor (Nrf2); Soluble guanylate cyclase; cGMP;
Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility
Keywords: سیکلاس گوانیلات حل کننده; sGC; soluble guanylate cyclase; NHE; normal hydrogen electrode; MbFeIII; methemoglobin; HbI; H2S-binding hemoglobin; MPO; myeloperoxidase; HbFeII-O2; oxyhemoglobin; sulfHb; sulfhemoglobin; sulfMb; sulfmyoglobin; CcO; cytochrome c oxidase; SQR; sulfide:q
Hydrogen sulfide inhibits preoptic prostaglandin E2 production during endotoxemia
Keywords: سیکلاس گوانیلات حل کننده; 3V; third ventricle; AOA; aminooxyacetate; AVPO; anteroventral preoptic region; cAMP; cyclic adenosine monophosphate; CBS; cystathionine β-synthase; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; CSE; cystathionine γ-lyase; icv; intracerebro
Role of soluble guanylate cyclase activation in the gastroprotective effect of the HO-1/CO pathway against alendronate-induced gastric damage in rats
Keywords: سیکلاس گوانیلات حل کننده; Alendronate; Gastric damage; Heme oxygenase-1; Carbon monoxide; Soluble guanylate cyclase;
The mediation of platelet quiescence by NO-releasing polymers via cGMP-induced serine 239 phosphorylation of vasodilator-stimulated phosphoprotein
Keywords: سیکلاس گوانیلات حل کننده; Nitric oxide (NO); Hemocompatibility; Platelets; Extracorporeal circulation (ECC); Vasodilator-stimulated phosphoprotein (VASP); cGMP; sGC; soluble guanylate cyclase; P-VASP (ser 239); serine 239 phosphorylation of VASP; P-VASP (ser 157); serine 157 phosp
CO, NO and O2 as vibrational probes of heme protein interactions
Keywords: سیکلاس گوانیلات حل کننده; IR; infrared; RR; resonance Raman; DFT; density functional theory; QM/MM; quantum mechanical/molecular mechanical; H-bond; hydrogen bond; HOMO; highest occupied molecular orbital; cyt P450cam; cytochrome P450 camphor hydroxylase; P450nor; nitric oxide red
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells
Keywords: سیکلاس گوانیلات حل کننده; AKT; protein kinase B; L-Arg; l-arginine; L-NAME; N-nitro-l-arginine methyl ester; NO; nitric oxide; NMDA; N-methyl-d-aspartate; MK-801; (5R,2S)-(1)5methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine hydrogen maleate; NOS; nitric-oxide synthase;
The trans effect of nitroxyl (HNO) in ferrous heme systems: Implications for soluble guanylate cyclase activation by HNO
Keywords: سیکلاس گوانیلات حل کننده; Nitric oxide; Soluble guanylate cyclase; Trans effect; Vasodilation; Nitric oxide signaling; Heme proteins
Synergistic Effects of BAY 60‐4552 and Vardenafil on Relaxation of Corpus Cavernosum Tissue of Patients with Erectile Dysfunction and Clinical Phosphodiesterase Type 5 Inhibitor Failure
Keywords: سیکلاس گوانیلات حل کننده; BAY 60‐4552; Corpus Cavernosum; Erectile Dysfunction; Vardenafil; Phosphodiesterase Type 5 Inhibitor; Soluble Guanylate Cyclase
Vasorelaxant action of the total alkaloid fraction obtained from Solanum paludosum Moric. (Solanaceae) involves NO/cGMP/PKG pathway and potassium channels
Keywords: سیکلاس گوانیلات حل کننده; FAT-SP; total alkaloid fraction of the root-bark of Solanum paludosum; NOS; NO synthase; sGC; soluble guanylate cyclase; GTP; guanosine triphosphate; cGMP; cyclic guanosine monophosphate; PKG; cGMP-dependent protein kinase G; Cav; L-type voltage-gated Ca2
Pulmonary, Gastrointestinal and Urogenital PharmacologyMechanism of relaxation and interaction with nitric oxide of the soluble guanylate cyclase stimulator BAY 41â2272 in mouse gastric fundus and colon
Keywords: سیکلاس گوانیلات حل کننده; BAY 41â2272; Cyclic GMP; Distal colon; Gastric fundus; Nitric oxide; Soluble guanylate cyclase;
Conformational selection mechanism governs oxygen ligation to H-NOX proteins
Keywords: سیکلاس گوانیلات حل کننده; Heme protein; Soluble guanylate cyclase; H-NOX protein; Molecular dynamics
Acidic triazoles as soluble guanylate cyclase stimulators
Keywords: سیکلاس گوانیلات حل کننده; Soluble guanylate cyclase; Enzyme; Stimulator; Triazoles