Original research articleAltered SOX9 genital tubercle enhancer region in hypospadias
Keywords: SOX9; Enhancer; Disorder of sex development; Genital tubercle; Hypospadias;
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Original ArticleActivation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma
Keywords: Sex-determining region on Y chromosome; Liver; Transgenic; Sex; Sox9; HCC; hepatocellular carcinoma; TG; transgenic; WT; wildtype; SRY; sex-determining region on Y chromosome; DEN; N-nitrosodiethylamine; PDGFRα; platelet-derived growth factor receptor α
Sox9 mediated transcriptional activation of FOXK2 is critical for colorectal cancer cells proliferation
Keywords: FOXK2; SOX9; Colorectal cancer;
Sox9 facilitates proliferation, differentiation and lipogenesis in primary cultured human sebocytes
Keywords: Sox; sex determining region Y-related high mobility group box; PPARγ; peroxisome proliferator-activated receptor γ; ORS; outer root sheath; HFs; hair follicles; SGs; sebaceous glands; HFSCs; hair follicle stem cells; FBS; fetal bovine serum; PBS; phosph
Polymorphisms in the SOX9 region and testicular disorder of sex development (38,XX; SRY-negative) in pigs
Keywords: Pig; Sex reversal; Intersexuality; DSD; SOX9; CNV;
KLF15 regulates in vitro chondrogenic differentiation of human mesenchymal stem cells by targeting SOX9
Keywords: KLF15; SOX9; Mesenchymal stem cell; Chondrocyte; Differentiation;
RAGE deficiency alleviates aortic valve calcification in ApoEâ/â mice via the inhibition of endoplasmic reticulum stress
Keywords: Aortic valve calcification; RAGE; ER stress; HMGB1; Sox9;
Curcumin inhibits glial scar formation by suppressing astrocyte-induced inflammation and fibrosis in vitro and in vivo
Keywords: Curcumin; NF-κb; SOX9; Glial scar; Dual-target therapy;
Data ArticleDataset of differentially expressed genes from SOX9 over-expressing NT2/D1 cells
Keywords: SOX9; NT2/D1 cells; Microarray; Sex determination;
Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters
Keywords: Endochondral ossification; Tranilast; SOX9; RUNX2;
Research reportβ-amyloid increases neurocan expression through regulating Sox9 in astrocytes: A potential relationship between Sox9 and chondroitin sulfate proteoglycans in Alzheimer's disease
Keywords: Sox9; Chondroitin sulfate proteoglycans; Neurocan; β-amyloid; Alzheimer's disease;
ZNF606 interacts with Sox9 to regulate chondrocyte differentiation
Keywords: ZNF606; Sox9; Chondrocyte differentiation; ZNF; Zinc-figure; KRAB; Kruppel-associated box domain; hUC-MSCs; human umbilical cord blood-derived mesenchymal stem cells; shRNA; short hairpin RNA;
Immunohistochemical expression of SOX9 protein in immature, mature, and neoplastic canine Sertoli cells
Keywords: Dog; Testis; Sertoli cells; Immunohistochemistry; SOX9;
Ddit3 suppresses the differentiation of mouse chondroprogenitor cells
Keywords: Sox9; sex determining region Y-type high mobility group box 9; C/EBP β; CCAAT/enhancer-binding protein β; GAG; proteoglycan; Col10a1; type X collagen; Runx2; runt related transcription factor 2; Col2a1; collagen II; Ddit3; DNA damage inducible transcrip
Characterization of p75 neurotrophin receptor expression in human dental pulp stem cells
Keywords: p75 Neurotrophin receptor; Dental pulp stem cells; Neural crest stem cells; SOX2; SOX9
RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes
Keywords: Chondrocyte; mRNA; SOX9; MMP13;
Joint Development Involves a Continuous Influx of Gdf5-Positive Cells
Keywords: Gdf5; synovial joint; skeletogenesis; interzone; progenitor cell; Sox9; lineage tracing; mouse
Sex-determining region Y-box 9 acts downstream of NADPH oxidase to influence the effect of leptin on PPARγ1 expression in hepatic stellate cells
Keywords: HSC; Hepatic stellate cell; PPARγ1; Peroxisome-proliferator activated receptor γ1; Sox9; Sex-determining region Y-box 9; TAA; Thioacetamide; SREBP-1c; Sterol regulatory element binding protein-1c; TF; Transcription factor; 4-HNE; 4-hydroxynonenal; α-SM
SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development
Keywords: AGRF; Australian genomic research facility; Amh; anti Müllerian hormone; BAC; bacterial artificial chromosome; CCL9; chemokine (C-C motif) ligand 9; CSLM; confocal laser scanning microscopy; CYP17A1; cytochrome p450 family 17, subfamily A, protein 1; Cyp
Sox9 overexpression in uterine epithelia induces endometrial gland hyperplasia
Keywords: Sox9; Transgenic mouse; Uterus; Endometrium; Cancer;
Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation
Keywords: Pancreas; Progenitors; Differentiation; Endocrine; Sox9;
Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix remodeling processes via RhoA signaling
Keywords: Stress fiber; F-actin; Compaction; Bioreactor; Alpha-smooth muscle actin; Alignment; SOX9; MMP-9; Mechanobiology; Biomechanics; Myofibroblast; Activation;
Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9
Keywords: Oligodendrocyte development; Sox9; Cerebellum
Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage
Keywords: ACs; articular chondrocytes; H3K4me2; histone 3 lysine 4 dimethylation; OA; osteoarthritis; WT; wild-type; IHC; immunohistochemistry; HE; haematoxylin and eosin; qPCR; quantitative real-time RT-PCR; P1; first passage of cultured cells; MeDIP; methylated D
MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation
Keywords: miR; microRNA; HDAC; histone deacetylase; OA; osteoarthritis; COL2A1; collagen 2; SOX9; SRY (sex-determining region Y)-box 9; RUNX2; Runt-related transcription factor 2; HAT; histone acetyltransferase; TSA; trichostatin A; Mmp13; matrix metalloproteinase
Conditional Sox9 ablation improves locomotor recovery after spinal cord injury by increasing reactive sprouting
Keywords: SOX9; Spinal cord injury; Neuroplasticity; CSPG; Reactive sprouting; Perineuronal nets;
Effect of microRNA-101 on apoptosis of rabbit condylar cartilage cells by inhibiting target gene SOX9
Keywords: miR-101; SOX9; Condyle cartilage; Apoptosis
Study on the mechanism of HIF1a-SOX9 in glucose-induced cardiomyocyte hypertrophy
Keywords: ANP, atrial natriuretic peptide; RT-PCR, reverse transcription; Sox9, SRY (sex determining region Y)-box 9; HIF1a, hypoxia inducible factor 1 alphaCardiomyocyte hypertrophy; SOX9; HIF1a
MicroRNA in prostate cancer
Keywords: DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb
BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
Keywords: BMP; Bmpr1a; Bmpr1b; Acvr1; Alk2; Alk3; Alk6; Smad4; Sox9; Cartilage; Mesenchymal condensation; Mouse;
Developmental exposure to bisphenol A (BPA) alters sexual differentiation in painted turtles (Chrysemys picta)
Keywords: BPA; bisphenol A; E2; 17β-estradiol; EDCs; endocrine disrupting compounds; IHC; immunohistochemistry; PBS; phosphate buffered saline; PCBs; polychlorinated biphenyls; SOX9; sex-determining region box 9, protein; Sox9; gene transcript; TBS; Tris-buffered
AMP-activated protein kinase (AMPK) activity negatively regulates chondrogenic differentiation
Keywords: Chondrocyte; AMPK; Metformin; Sox9; Egr-1;
SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis
Keywords: Osteoarthritis; Cartilage; Chondrocyte; ADAMTS; SOX9;
SOX9 Maintains Reserve Stem Cells and Preserves Radioresistance in Mouse Small Intestine
Keywords: Irradiation Injury; Intestinal Epithelium; Radioresistant Stem Cells; Gene Expression; aISC; active intestinal stem cell; EdU; ethynyl deoxyuridine; EGFP; enhanced green fluorescent protein; FACS; fluorescence-activated cell sorting; γH2AX; γ H2A histon
Role of c-Myb in chondrogenesis
Keywords: Acan; Aggrecan; A-Myb; Myb-related protein A (MYBL1); BMP; Bone morphogenetic protein; B-Myb; Myb-related protein B (MYBL2); c-Myb; cellular Myeloblastosis transcription factor; Col2a1; Collagen, type 2 alpha 1; Col10a1; Collagen, type 10 alpha 1; ECM; Ex
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
SOX9 dimerization domain mutation mimicking type 2 collagen disorder phenotype
Keywords: Type 2 collagen disorders; SOX9; Campomelic dysplasiaACD, acampomelic campomelic dysplasia; NGS, next generation sequencing
Atypical breakpoint in a t(6;17) translocation case of acampomelic campomelic dysplasia
Keywords: SOX9; Campomelic dysplasia; Translocation; Sex reversal; FISH
Histological, molecular and transcriptional analysis of PIS goats
Keywords: PIS goats; Gonadal masculinization; SOX9; PISTR1; Gene expression
Familial 46,XY sex reversal without campomelic dysplasia caused by a deletion upstream of the SOX9 gene
Keywords: XY sex reversal; Gonadal dysgenesis; SOX9; SRY; NR5A1;
SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms
Keywords: SOX9; Centroacinar cells; Pancreatic ductal adenocarcinoma; PanIN; IPMN; MCN; SCA; ACC; PET; SPN;
A tetracycline expression system in combination with Sox9 for cartilage tissue engineering
Keywords: Tet-on system; Sox9; Primary chondrocytes; Tissue engineering
The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression
Keywords: Transcriptional regulation; Catsper1; Sox5; Sox9; Calcium channels;
Cg-SoxE and Cg-β-catenin, two new potential actors of the sex-determining pathway in a hermaphrodite lophotrochozoan, the Pacific oyster Crassostrea gigas
Keywords: Sox9; β-catenin; Sex-determining pathways; Oyster; Gonadic differentiation
All-trans-retinoid acid (ATRA) suppresses chondrogenesis of rat primary hind limb bud mesenchymal cells by downregulating p63 and cartilage-specific molecules
Keywords: Chondrogenesis; Hind limb bud mesenchymal cells; Retinoic acid; p63; Sox9; Col2a1
Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice
Keywords: Chondrogenesis; MIA/CD-RAP; Sox9; Differentiation; Cell signalling; MIA-knockout mouse
Altered miRNA expression is associated with neuronal fate in G93A-SOD1 ependymal stem progenitor cells
Keywords: ALS; amyotrophic lateral sclerosis; Ccnd2; cyclin D2; Dlx2; distal-less homeobox 2; epSPCs; ependymal stem/progenitor cells; FALS; familial ALS; GAD 67; glutamic acid decarboxylase 67; GFAP; glial fibrillary acidic protein; Hes1; hairy and enhancer of spl
The effect of type II collagen on MSC osteogenic differentiation and bone defect repair
Keywords: Mesenchymal stem cell; Type II collagen; Osteogenesis; Cell adhesion; Integrin signaling; Bone healing; BMSC; bone marrow derived mesenchymal stem cell; ECM; extracellular matrix; VLA-2; very late antigen-2 (integrin α2β1 complex); FAK; focal adhesion k
Dynamics of BMP signaling in limb bud mesenchyme and polydactyly
Keywords: BMP; Limb development; FGF; Chondrogenesis; Sox9; Polydactyly; Gremlin
Peroxisome proliferator-activated receptor γ-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer
Keywords: miR-145; PPARγ; SOX9; Colorectal cancer; Invasiveness;