Src-mediated regulation of inflammatory responses by actin polymerization
Keywords: Actin cytoskeleton; Inflammation; Cytochalasin B; Src kinase; NF-κB
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Molecular mechanisms of testosterone action in spermatogenesis
Keywords: Testis; Non-genomic; MAP kinase; Transcription; Signal transduction; Src kinase
The nuclear localization of 3'-phosphoinositide-dependent kinase-1 is dependent on its association with the protein tyrosine phosphatase SHP-1
Keywords: Phospholipid; PDK1; Akt; Src kinase; Nuclear localization; SHP-1/PTP1C;
Castration-resistant Prostate Cancer: From New Pathophysiology to New Treatment Targets
Keywords: Prostate cancer; Androgens; Androgen receptor; Vascular endothelial growth factor; Immunotherapy; Apoptosis; Chaperone proteins; Clusterin; Insulin-like growth factor-1; Receptor activator of nuclear factor kappa B; Endothelin; Src kinase
Denitration of L-type calcium channel
Keywords: Nitric oxide; Tyrosine; Nitration; Ion channel; Src kinase; Smooth muscle
The actin cross-linking protein AFAP120 regulates axon elongation in a tyrosine phosphorylation-dependent manner
Keywords: Axon elongation; Growth cone; Src kinase; Actin cytoskeleton; AFAP
Two independent forms of endocytosis maintain embryonic cell surface homeostasis during early development
Keywords: Sea urchin; FM1-43; Endocytosis; PAO; Agatoxin; Src kinase; FK506; Staurosporine; PMA;
Chromogranin A activates diverse pathways mediating inducible nitric oxide expression and apoptosis in primary microglia
Keywords: Microglia; Chromogranin A; Extracellular signal-regulated kinase; Src kinase; Inducible nitric oxide synthase; Neurodegenerative disease; Annexin V; fluorescein isothiocyanate-annexin V; CgA; chromogranin A; ERK; extracellular signal-regulated kinase; Hoe
Japanese encephalitis virus infection stimulates Src tyrosine kinase in neuron/glia
Keywords: Japanese encephalitis virus; Inflammation; Protein tyrosine kinase; Src kinase;
Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease
Keywords: Muscarinic receptors; Glutamate receptors; Protein kinase C; Src kinase; Neocortex
Tyrosine phosphorylation of β2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity
Keywords: GTPase-activating protein; Diacylglycerol; Src kinase; Tyrosine phosphorylation; Epidermal growth factor; Cell spreading
Upregulation of Glucose-6-Phosphate Dehydrogenase and NAD(P)H Oxidase Activity Increases Oxidative Stress in Failing Human Heart
Keywords: Human heart; NAD(P)H oxidase; glucose-6-phosphate dehydrogenase; protein kinase C; Src kinase; free radicals
Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6
Keywords: HEK293; human embryonic kidney 293; PTP1B; tyrosine phosphatase 1B; DMHV; bis-(N,N-dimethyl-hydroxamido) hydroxo-vanadate; SOC; store operated Ca2+ channel; BiFC; bimolecular fluorescence complementation; PV; pervanadate; ROS; reactive oxygen species; GST
Proteolytic processing of phospholipase Cζ and [Ca2+]i oscillations during mammalian fertilization
Keywords: Calcium; Egg activation; Fertilization; Embryo development; Inositol 1,4,5-trisphosphate; Phospholipase Cζ; Proteolytic cleavage; Sperm factor; Src kinase
Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity
Keywords: Platelet; Nitric oxide synthase; cGMP; Tyrosine phosphorylation; Src kinase
Signal transduction at fertilization: The Ca2+ release pathway in echinoderms and other invertebrate deuterostomes
Keywords: Fertilization; Ca2+; PLCγ; Src kinase; Echinoderm
The Src family kinase, Lyn, is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors which stimulate its association with numerous other signaling molecules
Keywords: Pancreas; src; src kinase; lyn; Cholecystokinin; Pancreatic secretion; Pancreatic growth; Pancreatic growth factor
Nontransformed cells can normalize gap junctional communication with transformed cells
Keywords: Gap junctions; Intercellular communication; Connexin; Src kinase; Cell junctions; Transformation; Heterologous; Growth control;
Inhibition of tyrosine phosphorylation blocks hormone-stimulated calcium influx in an insect steroidogenic gland
Keywords: [Ca2+]; calcium ion concentration; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CYP17; 17-alpha-hydroxylase,17,20-lyase; DHEA(S); dehydroepiandrosterone sulfate; DMSO; dimethylsulfoxide; ERK; extracellular signal-regulated kinase; GDPβS; guanosine-5â
Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity
Keywords: Japanese encephalitis virus; Phosphorylation; Protein tyrosine kinase; Src kinase;
Brevetoxin augments NMDA receptor signaling in murine neocortical neurons
Keywords: VGSC; voltage-gated sodium channel; PbTx-2; brevetoxin-2; ERK1/2; extracellular signal-regulated kinases; CGC; cerebellar granule cells; [Ca2+]i; intracellular [Ca2+]; [Na+]i; intracellular [Na+]; PP2; 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]
Oestrogen-mediated tyrosine phosphorylation of caveolin-1 and its effect on the oestrogen receptor localisation: An in vivo study
Keywords: ERα-caveolin-1 interaction; Oestrogen; ICI 182 780; Tyrosine-phosphorylation; Src kinase;
Regulation of Src kinase activity during Xenopus oocyte maturation
Keywords: CSF; cytostatic factor; GVBD; germinal vesicle breakdown; IP3; inositol 1,4,5-trisphosphate; MAPK; mitogen-activated protein kinase; MPF; maturation-promoting factor; PI3K; phosphatidylinositol 3-kinase; PKA; cAMP-dependent protein kinase; PLC; phospholip
Two different pathways link G-protein-coupled receptors with tyrosine kinases for the modulation of growth and survival in human hematopoietic progenitor cells
Keywords: AG 82; AG 490, tyrphostin tyrosine kinase inhibitors; BFU-E; burst forming unit-erythroid; CXCR4; CXC-chemokine receptor 4, specifically recognizing CXCL12; Epo; erythropoietin; Flt-3L; ligand of flt-3 receptor; G-CSF; granulocyte colony-stimulating facto