Identification of cis-regulatory elements and trans-acting proteins of the rat carbohydrate response element binding protein gene
Keywords: ChREBP; Sp1; NF-Y; SREBP; Transcription;
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Androgen regulation of lipogenic pathways in the mouse meibomian gland
Keywords: meibomian gland; androgen; lipogenesis; gene expression; SREBP; tear film; dry eye; real-time PCR; mouse
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells
Keywords: Antidepressants; Mood-stabilizers; SREBP; Glial cells; SCD; HMGCS1
SREBP inhibits VEGF expression in human smooth muscle cells
Keywords: SREBP; VEGF; Atherosclerosis; Statin; Sp1; Transcription; Vascular cell;
DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway
Keywords: Cholesterol synthesis; SREBP; HMG-CoA reductase; Chaperone; Heat shock
The discrete and combined effect of SREBP-2 and SCAP isoforms in the control of plasma lipids among familial hypercholesterolaemia patients
Keywords: Familial hypercholesterolaemia; SCAP; SREBP; Genetic polymorphism; Gene–gene interaction
Characterization of the rat LDL receptor 5â²-flanking region
Keywords: Promoter; Response element; Transcription start site; Rapid amplification of cDNA end; Thyroid hormone; SREBP;
Pharmacological regulation of low density lipoprotein receptor expression: Current status and future developments
Keywords: LDL; low density lipoprotein; HDL; high density lipoprotein; TG; triglycerides; apoB; apolipoprotein B; SREBP; sterol responsive element binding protein; SCAP; SREBP cleavage activating protein; Insig; insulin-induced gene; NPC; Niemann-Pick Type C; OM; o
Disfunción endotelial
Keywords: Endotelio; Cardiovascular; Aterosclerosis; Ãxido nÃtrico; Endothelium; Cardiovascular disease; Atherosclerosis; Nitric oxide; ADMA; dimetilarginina asimétrica; ADP; adenosÃn difosfato; bFGF; factor de crecimiento de fibroblastos básico; CAM; molécul
Fatty acid elongases in mammals: Their regulation and roles in metabolism
Keywords: ACC; acetyl-CoA carboxylase; BAT; brown adipose tissue; CIG30; cold induced glycoprotein of 30Â kDa; CNS; central nervous system; DGAT; diacylglycerol acyltransferase; DHA; docosahexaenoic acid; Elo; yeast elongase; ELOVL; elongation of very long chain fa
Promoter analysis of the murine squalene epoxidase gene. Identification of a 205 bp homing region regulated by both SREBP'S and NF-Y
Keywords: Squalene epoxidase; Cholesterol; SREBP; NF-Y
Identification of a functional DNA binding site for the SREBP-1c transcription factor in the first intron of the human caspase-2 gene
Keywords: bHLH; basic helix-loop-helix; FAS; fatty acid synthase; HMG-CoA; 3-hydroxy-3-methylglutaryl Coenzyme A; LDLr; low-density lipoprotein receptor; SRE; sterol regulatory element; SREBP; sterol regulatory element binding protein; Human caspase-2; SREBP; L
Development of conjugated linoleic acid (CLA)-mediated lipoatrophic syndrome in the mouse
Keywords: Conjugated linoleic acid; Lipoatrophy; Insulin resistance; β-cell hyperplasia; Liver steatosis; CLA; conjugated linoleic acid; PPAR; peroxisome proliferator-activated receptor; SREBP; sterol responsive element-binding protein; TNF-α; tumor necrosis fact
A novel SREBP-1 splice variant: Tissue abundance and transactivation potency
Keywords: SREBP; sterol regulatory element binding protein; LDLR; low density lipoprotein receptor; bHLH-LZ; basic helix-loop-helix-leucine zipper; UCP2; uncoupling protein 2; SREBP-1; Alternative splicing; Transcriptional regulation;
Modulation of regulatory factors involved in cholesterol metabolism in response to feeding of pravastatin- or cholesterol-supplemented diet in chickens
Keywords: SREBP; sterol regulatory element binding protein; HMGR; 3-hydroxy-3-methylglutary coenzyme A reductase; LDLr; low density lipoprotein receptor; Sterol regulatory element binding protein-2 (SREBP-2); 3-hydroxy-3-methylglutary coenzyme A reductase (HMGR); L
Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes
Keywords: 2-DG; 2-deoxy-glucose; HOMA-R; homeostasis model assessment on insulin resistance; ipGTT; intraperitoneal glucose tolerance tests; IRS-2; insulin receptor substrate-2; ITT; insulin tolerance tests; ivGTT; intravenous glucose tolerance tests; NEFA; non-est
Supplementation with α-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of β-oxidation in Zucker fatty rats
Keywords: ACAT; acyl-CoA carnitine acyltransferase; ACO; acyl-CoA oxidase; ALA; α-linolenic acid; ALADG; α-linolenic acid-rich diacylglycerol; ALATG; α-linolenic acid-rich triacylglycerol; DG; diacylglycerol; DGAT; diacylglycerol acyltransferase; DHA; docosahexa
The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene:lanosterol cyclase activity
Keywords: IBS; imidazoline binding site; MOS; 2,3-monoepoxysqualene; DOS; 2,3 ;22,23-diepoxysqualene; OSC; oxidosqualene:lanosterol cyclase; α2-AR; α2-adrenoreceptor; I1R; imidazoline 1 receptor; LXR; liver X receptor; ABC-A1/G1; ATP-binding cassette transporter
The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors
Keywords: ASBT; apical sodium-dependent bile acid transporter; I-BABP; ileal bile acid-binding protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27A1; sterol 27-hydroxylase; CYP8B1; sterol 12α-hydroxylase; PPAR; peroxisome proliferator-activated receptors; RXR; ret
Adaptive evolution of the human fatty acid synthase gene: Support for the cancer selection and fat utilization hypotheses?
Keywords: FAS; Fatty acid Synthase; NADPH; Nicotinamide adenine dinucleotide phosphatase; PTEN; Phosphatase and tensin homolog; MAP(K1); Mitogen-activated protein (kinase 1); PI-3K; Phosphatidylinositol-3 kinase; SREBP; Sterol regulatory Element binding Proteins; C
Deficiency of PPARα disturbs the response of lipogenic flux and of lipogenic and cholesterogenic gene expression to dietary cholesterol in mouse white adipose tissue
Keywords: NEFA; non-esterified fatty acid; TAG; triacylglycerol; FAS; fatty acid synthase; ACC; acetyl CoA carboxylase; SREBP; sterol regulatory binding protein; PPAR; peroxisome proliferator-activated receptor; LXR; liver-X receptor; LDL; low-density lipoprotein;
Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet
Keywords: ABCA1; ATP-binding cassette transporter A1; ABCG5; ATP-binding cassette transporter G5; ABCG8; ATP-binding cassette transporter G8; ALT; alanine aminotransferase; apoE; apolipoprotein E; apoEâ/â; apoE-deficient mice; ETV6; ETS variant gene 6; FDPS; fa
Molecular mechanisms and regulation of ceramide transport
Keywords: ARF; ADP-ribosylation factor; CERT; ceramide transport protein; CGlcT; ceramide glucosyltransferase; CHO; Chinese hamster ovary; DAG; diacylglycerol; D609; tricyclodecan-9-yl xanthate; HPA-12; N-(3-hydroxyl-1-hydroxylmethyl-3-phenylpropyl)dodecanamide; ER
Antiepileptic popular ketogenic diet: emerging twists in an ancient story
Keywords: AA; arachidonic acid; AED(s); antiepileptic drug(s); BMCP; brain mitochondrial protein (also referred to as UCP5); CACT; carnitine acylcarnitine translocase; CCK; cholecystokinine; COX; cyclooxygenase; CPT I; carnitine palmitoyltransferase type I; CPT II;