دانلود مقالات ISI درباره Stat3 + ترجمه فارسی

Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)

Keywords: STAT3; Transcription factors; Small molecule inhibitors; Anticancer drugs; Cancer therapy; Mechanism of action; Computational modeling; Molecular dynamic simulation; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha

Keywords: CNTF(R); Ciliary neurotrophic factor (receptor); EGF; Epidermal growth factor; ERK; Extracellular signal-regulated kinase; FRα; Folate receptor alpha; GPI; glycophosphatidylinositol; IFN; Interferon; IL-6(R); Interleukin 6 (receptor); ISG; Interferon sti

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Downregulation of STAT3 phosphorylation enhances tumoricidal effect of IL-15-activated dendritic cell against doxorubicin-resistant lymphoma and leukemia via TNF-α

Keywords: DL; Dalton lymphoma; DC; dendritic cells; IL-15; interleukin 15; CUB; cucurbitacin I; NDC; DC from normal; DLDC; DC from Dalton lymphoma mice; E:T; effector target ratio; DOX; doxorubicin; DOX-R; doxorubicin resistance; TNF-α; Dendritic cells; IL-15; Dox

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

FGF2 alleviates PTSD symptoms in rats by restoring GLAST function in astrocytes via the JAK/STAT pathway

Keywords: PTSD; FGF2; Astrocyte; GLAST; STAT3;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Acetyl-11-keto-β-boswellic acid reduces retinal angiogenesis in a mouse model of oxygen-induced retinopathy

Keywords: SHP-1; STAT3; VEGF; Cytochrome c; CD31-Immunohistochemistry; Electroretinogram; HRMECs; AKBA; acetyl-11-keto-β-boswellic acid; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; EBM-2; Endothelial Basal Medium-2; ELISA; enzyme-linked imm

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway

Keywords: Farnesol; STAT3; Multiple myeloma; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Antiproliferative, DNA intercalation and redox cycling activities of dioxonaphtho[2,3-d]imidazolium analogs of YM155: A structure-activity relationship study

Keywords: YM155; DNA intercalation; Redox cycling; Cell viability; Survivin suppressant; Apoptosis; p54nrb; nuclear RNA-binding protein; ILF3/NF110; interleukin enhancer binding factor 3/nuclear factor 110; SP1; specificity factor 1; STAT3; signal transducer and ac

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Astrocytic TLR4 expression and LPS-induced nuclear translocation of STAT3 in the sensory circumventricular organs of adult mouse brain

Keywords: AP; area postrema; BBB; blood-brain barrier; Cox2; cyclooxygenase-2; CVOs; circumventricular organs; GFAP; glial fibrillar acidic protein; icv; intracerebroventricular; IL-1β; interleukin-1β; LPS; lipopolysaccharide; NF-κB; nuclear factor-κB; OVLT;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Quantitative proteomic analysis of global effect of LLL12 on U87 cell's proteome: An insight into the molecular mechanism of LLL12

Keywords: Glioblastoma multiforme; STAT3; LLL12; Quantitative proteomics; Glycolysis; BTF3;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3

Keywords: Ascochlorin; HCC; STAT3; PIAS3; Invasion; Orthotopic modelASC, ascochlorin; STAT3, signal transducer and activator of transcription 3; HCC, hepatocellular carcinoma; FBS, fetal bovine serum; MTT, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2H-tetrazolium

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction with STAT3 and importinβ

Keywords: ARHI; Aplasia Ras Homologue member I; STAT3; Signal Transducer and Activator of Transcription 3; NTD; N-terminal domain; CCD; Coiled-coil domain; DBD; DNA binding domain; LD; Linker domain; SH2; Src-homology-2 domain; TAD; transactivation domain; LOH; los

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Mmu-miR-351 attenuates the survival of cardiac arterial endothelial cells through targeting STAT3 in the atherosclerotic mice

Keywords: miR-351; STAT3; Atherosclerosis (AS);

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

High-affinity interaction between interleukin-11 and S100P protein

Keywords: Cancer; Interleukin; S100 protein; Protein-protein interaction; STAT3; IL-11; interleukin-11; rWT IL-11; recombinant human interleukin-11 omitting the N-terminal Pro residue of the mature protein (residues 23-199 of Swiss-Prot entry P20809); IL-11Rα; i

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl)amino]-2-oxoethyl(2,6-dichlorophenyl)acetate, suppresses helper T cell differentiation in vitro and collagen-induced arthritis in vivo

Keywords: Helper T cells; Cytokine signaling; Th17; JAK1; STAT3;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

Keywords: GBM; glioblastoma multiforme; let-7a; lethal-7a; miRNA; microRNA; TCGA; The Cancer Genome Atlas; GLUT; glucose transporter; PKM2; pyruvate kinase M2; PDK; pyruvate dehydrogenase kinase; MGMT; O6-methylguanine-DNA methyltransferase; GSK3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting protein-protein interactions (PPIs) of transcription factors: Challenges of intrinsically disordered proteins (IDPs) and regions (IDRs)

Keywords: Protein-protein interactions; Intrinsically disordered proteins; Transcription factors; Anticancer therapy; c-MYC; STAT3; HIF-1; β-catenin;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting strategies on miRNA-21 and PDCD4 for glioblastoma

Keywords: GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Human fibrocyte-derived exosomes accelerate wound healing in genetically diabetic mice

Keywords: Chronic wound; Diabetes; Exosome; Fibrocyte; Wound healing; α-SMA; α-smooth muscle actin; FGF; fibroblast growth factor; CK; cytokeratin; CM; conditioned medium; COL1; type I collagen; COL3; type III collagen; CT; threshold cycle; DMEM; Dulbecco's modif

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases

Keywords: PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Dietary cocoa inhibits colitis associated cancer: a crucial involvement of the IL-6/STAT3 pathway

Keywords: Colitis associated cancer; Cocoa; NF-κB; STAT3; Apoptosis; IL-6;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

JAK/STAT pathway regulation of GABAA receptor expression after differing severities of experimental TBI

Keywords: Traumatic brain injury; GABAA receptor; JAK/STAT pathway; STAT3;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice

Keywords: IL6; IBD Progression; Mouse Model; Chronic Inflammation; CAC; colitis-associated colon cancer; CD; Crohn's disease; CRC; sporadic colon cancer; IL; interleukin; miR; microRNA; mRNA; messenger RNA; PCR; polymerase chain reaction; qPCR; quantitative polym

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2015 سفارش ترجمه

Areca catechu L. (Arecaceae): A review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

Keywords: AA; arachidonic acid; ACAT; acyl coenzyme A-cholesterol acyltransferase; ACE; angiotensin-converting enzyme; ACEAN; ethyl acetate extracts of areca nut; AchE; acetylcholinesterase; AchR; acetylcholine receptors; ADP; adenosine diphosphate; AEAN; acetone e

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2015 سفارش ترجمه

Short communicationAngoline: A selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum

Keywords: STAT3; signal transducer and activator of transcription protein 3; JAK; Janus kinase; NF-κB; nuclear factor κB; IL-6; Interleukin-6; TNFα; tumor necrosis factor-α; IFN; interferon γ; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Caffeine attenuated ER stress-induced leptin resistance in neurons

Keywords: STAT3; Caffeine; Leptin; Endoplasmic reticulum stress;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Master regulator of intestinal disease: IL-6 in chronic inflammation and cancer development

Keywords: Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Colorectal cancer; Cytokines; Interleukin-6; STAT3; SOCS3; JAK

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Astrogliosis as a therapeutic target for neurodegenerative diseases

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine triphosphate; BB14®; nerve growth factor-like peptide; BDNF; brain-derived neurotrophic factor; Ca2+; calcium; CNS; central nervous system; COX-1/2; cyclooxygenase-1/2; EAAC1; ex

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK+ anaplastic large cell lymphoma

Keywords: Crizotinib; STAT3; ALCL; NPM-ALK; MCL-1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells

Keywords: cagA; cytotoxin-associated gene A; CD; cytoplasmic domain; ChIP; chromatin immunoprecipitation; MOI; multiplicity of infection; STAT; signal transducer and activator of transcription; Cancer; Methylation; Mucin; Promoter; STAT3;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

microRNA-7: A tumor suppressor miRNA with therapeutic potential

Keywords: ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Signals for increase of μ-opioid receptor expression in muscle by hyperglycemia

Keywords: MOR; μ-opioid receptor; STAT3; signal transducer and activator of transcription 3; STZ rats; streptozotocin-induced diabetic rats; HG; high glucose; 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; PBS; phosphate buffer solution; RI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Signal transducers and activators of transcription (STATs) gene polymorphisms related with susceptibility to rheumatic heart disease in north Indian population

Keywords: RHD; STAT3; STAT5b; Indian population;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

TL1A increased the differentiation of peripheral Th17 in rheumatoid arthritis

Keywords: TL1A; tumor necrosis factor-like protein 1A; DR3; death receptor 3; RA; rheumatoid arthritis; CD4; cluster of differentiation 4; IL; interleukin; Th17; IL-17-producing helper T cells; TGF-β; transforming growth factor β; STAT3; signal transducer and act

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Avian blood induced intranuclear translocation of STAT3 via the chicken leptin receptor

Keywords: Avian; Bioassay; Leptin; STAT3; Signal transduction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The binding of silibinin to ERp57

Keywords: Silibinin; ERp57; Ref1; Protein ligand interaction; STAT3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model

Keywords: Lung cancer; Oncogene addiction; EGFR; JAK2; STAT3; Transgenic mice;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Carcinogenic metalloid arsenic induces expression of mdig oncogene through JNK and STAT3 activation

Keywords: Metalloid; Arsenic; Mdig; STAT3; JNK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Shikonin suppresses IL-17-induced VEGF expression via blockage of JAK2/STAT3 pathway

Keywords: Shikonin; IL-17; STAT3; VEGF

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

AAG8 promotes carcinogenesis by activating STAT3

Keywords: AAG8; STAT3; Cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Blockage of Stat3 enhances the sensitivity of NSCLC cells to PI3K/mTOR inhibition

Keywords: Akt; Bim; CHOP; mTOR; PI3K; Stat3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The role of wogonin in controlling SOCS3 expression in neuronal cells

Keywords: Wogonin; SOCS3; Neuroinflammation; PI3K; AP1; STAT3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Novel distribution of calreticulin to cardiomyocyte mitochondria and its increase in a rat model of dilated cardiomyopathy

Keywords: Calreticulin; Mitochondria; Apoptosis; STAT3; Dilated cardiomyopathy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Investigation of JAK1 and STAT3 polymorphisms and their gene-gene interactions in nonspecific digestive disorder of rabbits

Keywords: JAK1; Janus kinase 1; STAT3; signal transducer and activator of transcription 3; cSNPs; coding single nucleotide polymorphisms; SH2; Src homology-2 domains; NSDD; nonspecific digestive disorder; IBD; inflammatory bowel disease; CD; Crohn's disease; UC; ul

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line

Keywords: anticancer; herbal extract; Korean medicine; Stat3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Bioactive sesquiterpene lactones and other compounds isolated from Vernonia cinerea

Keywords: Vernonia cinerea; Asteraceae; Sesquiterpene lactone; STAT3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ursolic acid ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney by inhibiting the STAT3 and NF-κB activities

Keywords: COX-2; cyclooxygenase-2; IL-6; interleukin-6; NF-κB; nuclear factor-κB; 8-OhdG; 8-hydroxy-2-deoxyguanosine; UA; ursolic acid; ROS; reactive oxygen species; STAT3; transcription 3; TBARS; thiobarbituric acid reactive substances; TNF-α; tumor necrosis fa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Aberrant hypomethylated STAT3 was identified as a biomarker of chronic benzene poisoning through integrating DNA methylation and mRNA expression data

Keywords: Chronic benzene poisoning; Biomarkers; DNA methylation; STAT3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

HPV16 E2 enhances the expression of NF-κB and STAT3 target genes and potentiates NF-κB activation by inflammatory mediators

Keywords: HPV; Inflammation; NF-κB; STAT3; Pin1; Cytokines; Chemokines

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Low incidence of IL6ST (gp130) mutations in exon 6 in lung cancer of a Chinese cohort

Keywords: Lung cancer; gp130; exon 6; mutation; STAT3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Heat stress stimulates hepcidin mRNA expression and C/EBPα protein expression in aged rodent liver

Keywords: Iron; Hypoferremia; Inflammation; IL-6; STAT3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه