Keywords: ژنومیک سازه; Data mining; Structural genomics; Local alignments; Profile-HMM; Regular expression; Antimicrobial activity prediction; Molecular modelling;
مقالات ISI ژنومیک سازه (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ژنومیک سازه; CAL/G; concanavalin A-like lectin/glucanase; GHs; glycoside hydrolases; POOL; Partial Order Optimum Likelihood; 6-HG; six-hairpin glycosidase; SG; Structural Genomics; SALSA; Structurally Aligned Local Sites of Activity; THEMATICS; THEoretical Microscopic
Keywords: ژنومیک سازه; Drug discovery; Homolog-rescue; Structural genomics; Enzyme active site;
Keywords: ژنومیک سازه; Structural genomics; Protein function prediction; Local structure methods; Computational chemistry
Keywords: ژنومیک سازه; Protein-protein interactions; Protein binding sites; Coverage of protein families; PPI; Structural genomics;
Keywords: ژنومیک سازه; IMP; integral membrane protein; GFP; green fluorescent protein; FSEC; fluorescence-detected size-exclusion chromatography; IMAC; immobilized metal affinity chromatography purification; SEC; size-exclusion chromatography; GF; gel filtration; AGF; analytica
Keywords: ژنومیک سازه; Interactome; Chemical genomics; Structural genomics; Molecular dynamics simulation
Assessing the progress of Mycobacterium tuberculosis H37Rv structural genomics
Keywords: ژنومیک سازه; Mycobacterium tuberculosis; Structural genomics; Drug target;
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure–activity relationships
Keywords: ژنومیک سازه; Short-chain dehydrogenase/reductase; Chemical biology; Structural genomics; Differential scanning fluorimetry; Metabolism
Basic Tilted Helix Bundle - A new protein fold in human FKBP25/FKBP3 and HectD1
Keywords: ژنومیک سازه; Immunophillins; NMR structure; Structural genomics; FKBP25; FKBP3; HectD1; YY1;
Structural insights into conserved l-arabinose metabolic enzymes reveal the substrate binding site of a thermophilic l-arabinose isomerase
Keywords: ژنومیک سازه; Structural genomics; Prediction; Substrate binding site; l-Arabinose isomerase; Thermophilic;
Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity
Keywords: ژنومیک سازه; Toxin-antitoxin system; Structural genomics; Ribonuclease; H. pylori; Metal;
Utilization of protein intrinsic disorder knowledge in structural proteomics
Keywords: ژنومیک سازه; Proteomics; Structural genomics; Structural proteomics; Intrinsically disordered protein
Fractional factorial approach combining 4 Escherichia coli strains, 3 culture media, 3 expression temperatures and 5 N-terminal fusion tags for screening the soluble expression of recombinant proteins
Keywords: ژنومیک سازه; Fractional factorial approach; Design of experiment; Recombinant protein; Escherichia coli; Structural genomics
AcrB contamination in 2-D crystallization of membrane proteins: Lessons from a sodium channel and a putative monovalent cation/proton antiporter
Keywords: ژنومیک سازه; Sparse matrix; Continuous-flow dialysis; Electron crystallography; 2dx; Membrane proteins; Structural genomics; 2-D Crystal; 2-D; two dimensional; 3-D; three dimensional; β-DM; n-Decyl-β-D-maltoside; β-DDM; n-Dodecyl-β-D-maltoside; DMPC; 1,2-dimyristo
Inaugural structure from the DUF3349 superfamily of proteins, Mycobacterium tuberculosis Rv0543c
Keywords: ژنومیک سازه; Tuberculosis; Circular dichroism; Structural genomics; Protein dynamics
Computational approaches to selecting and optimising targets for structural biology
Keywords: ژنومیک سازه; MSA; Multiple Sequence Alignment; PTM; Post Translational Modification; SSPF; Scottish Structural Proteomics Facility; MCC; Matthew's correlation coefficient; AROC; Area Under the Receiver Operator Characteristic curve; Target selection; Crystallisation
Structural biology of Mycobacterium tuberculosis proteins: The Indian efforts
Keywords: ژنومیک سازه; Structural genomics; X-ray crystallography; NMR; Inhibitor design;
The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs
Keywords: ژنومیک سازه; Aminoacyl-tRNA synthetase; Protozoa; Structural genomics
Solution structure of Rv2377c-founding member of the MbtH-like protein family
Keywords: ژنومیک سازه; Tuberculosis; Siderophore assembly; Mycobactin; Circular dichroism; Structural genomics; Protein dynamics;
Crystal structure and functional insight of HP0420-homolog from Helicobacter felis
Keywords: ژنومیک سازه; Crystal structure; Helicobacter; Hot-dog fold; Structural genomics; HP0420
High-throughput expression and purification of membrane proteins
Keywords: ژنومیک سازه; Membrane proteins; Detergent; Expression; High-throughput; Structure; Structural genomics;
Automated electron microscopy for evaluating two-dimensional crystallization of membrane proteins
Keywords: ژنومیک سازه; Automation; Crystallography; Electron microscopy; Membrane protein; Protein structure; Structural genomics; Two-dimensional crystal
High-throughput production of human proteins for crystallization: The SGC experience
Keywords: ژنومیک سازه; Ligation-independent cloning; Structural genomics; Protein expression; Protein purification; Structure prediction; Open source;
The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium
Keywords: ژنومیک سازه; Structural genomics; High-throughput protein production; Construct optimization; Disorder prediction; Ligation-independent cloning; Multiple Displacement Amplification; Laboratory Information Management System; Protein Structure Initiative; NMR; X-ray cry
Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography
Keywords: ژنومیک سازه; Membrane proteins; Structural genomics; Yeast; Crystallography; Detergents; Protein expression
Crystallization NoteAcrB et al.: Obstinate contaminants in a picogram scale. One more bottleneck in the membrane protein structure pipeline
Keywords: ژنومیک سازه; AcrB; Succinate dehydrogenase; Heterologous expression; Picogram crystallization; Membrane protein contaminants; Structural genomics;
Meta prediction of protein crystallization propensity
Keywords: ژنومیک سازه; Structural genomics; X-ray crystallography; Crystallization propensity prediction; Protein structure; Protein crystallization
International research networks in viral structural proteomics: Again, lessons from SARS
Keywords: ژنومیک سازه; SARS-CoV; Infectious diseases; Structural genomics; FSPS; VIZIER;
Effective high-throughput overproduction of membrane proteins in Escherichia coli
Keywords: ژنومیک سازه; Membrane proteins; His-tag; Structural genomics; Escherichia coli; Auto-induction; Protein production; Legionella pneumophila; Legionnaires’ disease
Rapid classification of protein structure models using unassigned backbone RDCs and probability density profile analysis (PDPA)
Keywords: ژنومیک سازه; Unassigned NMR data; Residual dipolar coupling; PDPA; Protein structure modeling; Powder pattern analysis; Structural genomics;
An approach to quality management in structural biology: Biophysical selection of proteins for successful crystallization
Keywords: ژنومیک سازه; Protein crystallization; Protein fold; Structural genomics; Dynamic light scattering (DLS); Differential scanning calorimetry (DSC); Fourier-transform infrared spectroscopy (FTIR)
Estimation of relative order tensors, and reconstruction of vectors in space using unassigned RDC data and its application
Keywords: ژنومیک سازه; Unassigned NMR data; Residual dipolar coupling; Protein structure modeling; Structural genomics;
A robust purification strategy to accelerate membrane proteomics
Keywords: ژنومیک سازه; Membrane; Protein; Structural genomics; Proteomics; Detergent; CorA; Magnesium; Channel; Crystal; Rhomboid; Dodecylmaltoside
New vectors for co-expression of proteins: Structure of Bacillus subtilis ScoAB obtained by high-throughput protocols
Keywords: ژنومیک سازه; Expression vectors; Co-expression; Co-purification; Coenzyme A transferase; High throughput; Structural genomics;
Defining and solving the essential protein–protein interactions in HIV infection
Keywords: ژنومیک سازه; HIV; HIV replication cycle; HIV capsid; HIV core; Preintegration complex; Optical microscopy; Cryoelectron tomography; Coherent anti-Stokes Raman scattering microscopy; Structural genomics
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms
Keywords: ژنومیک سازه; Pf; Plasmodium falciparum; Py; Plasmodium yoelii; Pb; Plasmodium berghei; Pv; Plasmodium vivax; Pk; Plasmodium knowlesi; Cp; Cryptosporidium parvum; Tg; Toxoplasma gondii; Structural genomics; Heterologous protein expression; Apicomplexa; Malaria; Crystal
Ligation independent cloning vectors for expression of SUMO fusions
Keywords: ژنومیک سازه; Ligation independent cloning; LIC; SUMO; Subtractive purification; Expressed protein ligation; EPL; Structural genomics
Confronting high-throughput protein refolding using high pressure and solution screens
Keywords: ژنومیک سازه; Inclusion bodies; Aggregation; Misfolding; Solubilization; Protein recovery; Protein refolding; Small molecules assisted refolding; Fractional factorial screen; High hydrostatic pressure; Automation; High-throughput; Structural genomics
A normalised scale for structural genomics target ranking: The OB-Score
Keywords: ژنومیک سازه; HTPX; Structural genomics; Target selection; Pfam; Bioinformatics
The potential impact of structural genomics on tuberculosis drug discovery
Keywords: ژنومیک سازه; Biochemistry; Drug Discovery; Pharmaceutical ScienceX-ray crystallography; NMR; structural genomics; drug design; TB; antibiotics
RF cloning: A restriction-free method for inserting target genes into plasmids
Keywords: ژنومیک سازه; Restriction-free cloning; Structural genomics; High-throughput cloning; Ligation independent cloning
Focusing in on structural genomics: The University of Queensland structural biology pipeline
Keywords: ژنومیک سازه; High throughput crystallography; Protein expression; Macrophage proteins; Crystallization; Structural genomics
An expression vector tailored for large-scale, high-throughput purification of recombinant proteins
Keywords: ژنومیک سازه; High-throughput; Structural genomics; Maltose-binding protein; TVMV protease; Ligation-independent cloning;
Crystallizing new approaches for antimicrobial drug discovery
Keywords: ژنومیک سازه; Antimicrobial drug discovery; Structural genomics; Structure guided drug discovery; Antibiotics; Antibacterials
Semliki Forest virus vectors for overexpression of 101 G protein-coupled receptors in mammalian host cells
Keywords: ژنومیک سازه; G protein-coupled receptors; Semliki Forest virus; Structural genomics; Structural biology; Recombinant expression; Large-scale production; Mammalian cell lines; Immunodetection; Binding assays
Evaluation of models for the evolution of protein sequences and functions under structural constraint
Keywords: ژنومیک سازه; Coarse-grained models; Folding; Binding; Population dynamics; Structural genomics; Molecular evolution;
Efficient Prediction of Nucleic Acid Binding Function from Low-resolution Protein Structures
Keywords: ژنومیک سازه; DNA-binding; protein–DNA interactions; function prediction; structural genomics; dipole momentROC, receiver operator characteristic; AUC, area under the ROC curve; RMSD, root-mean-square deviation; PDB, Protein Data Bank
Fold Independent Structural Comparisons of Protein–Ligand Binding Sites for Exploring Functional Relationships
Keywords: ژنومیک سازه; geometric hashing; SitesBase; structural genomics; 3D structure comparisonPDB, Protein Data Bank
Travel Depth, a New Shape Descriptor for Macromolecules: Application to Ligand Binding
Keywords: ژنومیک سازه; PDB, Protein Data Bankdepth; molecular surface; ligand binding; structural genomics; computational geometry