Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse
Keywords: خود را; Tau; Parkinson's disease; Alzheimer's disease; Clioquinol; Iron;
مقالات ISI خود را (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Investigating degeneration of the retina in young and aged tau P301L mice
Keywords: خود را; Aging; Neurodegeneration; Retina; Retinal ganglion cells; Tau;
Research ReportErythropoietin attenuates Alzheimer-like memory impairments and pathological changes induced by amyloid β42 in mice
Keywords: خود را; Erythropoietin; Alzheimer׳s disease; Amyloid β; Tau; Apoptosis;
Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways
Keywords: خود را; Alzheimer; Abeta; Amyloid; Tau; Genetics; Next generation sequencing; PICALM; SORL1; EPHA1; APOE; APP; Vaccine; Secretase; Nicastrin; Presenilin; PSEN1; Neurodegeneration; Dementia;
Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity
Keywords: خود را; Tau; Mitochondria; Calorie restriction; ATP synthase; Alzheimer's; Complex I;
Correlation between decreased CSF α-synuclein and Aβ1-42 in Parkinson disease
Keywords: خود را; Parkinson's disease; Cerebrospinal fluid; α-Synuclein; Aβ1-42; Tau; Nondemented; PiB; Imaging;
Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor
Keywords: خود را; Alzheimer's disease; Transgenic mouse models; Amyloid beta; Tau; Oxidative stress; Lipid peroxidation; Isoprostanes;
Task-evoked fMRI changes in attention networks are associated with preclinical Alzheimer's disease biomarkers
Keywords: خود را; Alzheimer; Attention; Biomarkers; fMRI; Dementia; Amyloid; Alzheimer's disease; tau; ptau;
C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease
Keywords: خود را; Neurogranin; CSF biomarker; Plasma biomarker; Prognostic biomarker; Alzheimer's disease; Mild cognitive impairment; tau; Amyloid; γ-secretase; ELISA; Ratio amyloid β;
Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta
Keywords: خود را; Alzheimer's disease; BDNF; TrkB; Amyloid-beta; Tau; Human postmortem;
Diagnostic impact of CSF biomarkers for Alzheimer's disease in a tertiary memory clinic
Keywords: خود را; Dementia; Alzheimer's disease; Clinical practice; Diagnostic impact; Assessment of cognitive disorders; Cerebrospinal fluid; Amyloid-β1-42; Tau; Biomarkers;
JNK-interacting protein 1 mediates Alzheimer's-like pathological features in AICD-transgenic mice
Keywords: خود را; Alzheimer's; APP; AICD; JNK; JNK-interacting protein 1; Tau;
Association between MAPT haplotype and memory function in patients with Parkinson's disease and healthy aging individuals
Keywords: خود را; Parkinson's disease; Dementia; Aging; Memory; fMRI; Hippocampus; MAPT; Genetics; Tau; Cognitive impairment; Picture recognition;
Down syndrome and Alzheimer's disease: Common pathways, common goals
Keywords: خود را; Down syndrome; Alzheimer's disease; Dementia; Animal models; Ts65Dn; Drug discovery; Neuroinflammation; Cognitive assessment; Amyloid precursor protein; Beta-amyloid; Tau; Clinical trials; Biomarkers; Trisomy 21; ADNI; DS-Connect; Neuroimaging; Workshop;
In vitro metacyclogenesis of Trypanosoma cruzi induced by starvation correlates with a transient adenylyl cyclase stimulation as well as with a constitutive upregulation of adenylyl cyclase expression
Keywords: خود را; cAMP; cyclic AMP; AC; adenylyl cyclase; THT; trypanosome hexose transporter; TAU; triatomine artificial urine; VSG; variable surface glycoprotein; T. cruzi; Metacyclogenesis; cAMP; Adenylyl cyclase; Parasite differentiation;
Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cells
Keywords: خود را; HSV-2 infection; Tau; Amyloid-β; Autophagy; Neurodegeneration; Alzheimer's disease;
Resilience of Precuneus Neurotrophic Signaling Pathways Despite Amyloid Pathology in Prodromal Alzheimer's Disease
Keywords: خود را; Alzheimer's disease; Amyloid; Mild cognitive impairment; Neuropathology; Neurotrophic factors; Tau;
Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line
Keywords: خود را; 36B4; ribosomal protein, large, P0; AADC; aromatic l-amino acid decarboxylase; AD; Alzheimer's disease; ALPL/TNAP/Akp2; tissue-nonspecific alkaline phosphatase; AT; annealing temperature; ATP; adenosine triphosphate; ADP; adenosine diphosphate; AMP; adeno
Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo
Keywords: خود را; Tau; Tau oligomers; Alzheimer; Hyperthermia; Oxidative stress; DNA damage; RNA damage; Methylene Blue;
Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology
Keywords: خود را; AD; Alzheimer´s disease; Aβ; amyloid-β peptide; MV; membrane vesicles; NFTs; neurofibrillary tangles; PMCA; plasma membrane Ca2+-ATPase; SERCA; sarco(endo)plasmic reticulum Ca2+-ATPase; SPCA; secretory pathway Ca2+-ATPase; Tau; Calcium; PMCA; Aging; Al
Project ReportRelationship between hippocampal atrophy and neuropathology markers: A 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol
Keywords: خود را; Hippocampus; Atrophy; Hippocampal atrophy; Alzheimer; Dementia; Hippocampal segmentation; Hippocampal volumes; Subfields; Pathology; Braak; CERAD; Amyloid; Tau; Neuronal count; validation;
Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative
Keywords: خود را; Multiple system atrophy; α-synuclein; Tau; Glia; Cerebrospinal fluid; Blood
Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset
Keywords: خود را; Amyloid-β; Amyloid precursor protein; APP/PS1 mice; Glycogen synthase kinase β; Gliosis; Tau; TUDCA;
Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease
Keywords: خود را; Alzheimer's disease; Nerve growth factor; Choline acetyltransferase; Acetyl cholinesterase; tau; Amyloid-β; Nicotine receptors; PET; MRI;
Modeling the complex pathology of Alzheimer's disease in Drosophila
Keywords: خود را; Drosophila; Alzheimer's disease; Disease models; Neurodegeneration; Aβ42; APP; Tau; Genetics; Pathology
Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer's disease
Keywords: خود را; APP; PS1; Tau; Sleep; EEG; Alzheimer's disease;
Neurodegenerative CSF markers in genetic and sporadic PD: Classification and prediction in a longitudinal study
Keywords: خود را; Parkinson; CSF; Tau; Abeta; LRRK2; GBA;
Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats infused with β-amyloid
Keywords: خود را; GOAT; ghrelin O-acyltransferase; GHSR; growth hormone secretagogue receptor; LV; lateral ventricle; ICV; intracerebroventricular; AD-G; Acyl-ghrelin ICV infusion; AD-DES-G; Des-acyl-ghrelin ICV infusion; AD-C; phosphate buffered saline ICV infusion; Non-A
Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice
Keywords: خود را; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid-β precursor protein; BBB; blood-brain barrier; BCI; brain clearance index; CAA; cerebral amyloid angiopathy; DEA; diethylamine; EVOO; extra-virgin olive oil; FA; formic acid; IDE; insulin degradi
Nonlinear cerebral atrophy patterns across the Alzheimer's disease continuum: impact of APOE4 genotype
Keywords: خود را; MRI; VBM; Brain; Biomarkers; Neuroinflammation; Amyloid; Tau;
Review Article2014 Update of the Alzheimer's Disease Neuroimaging Initiative: AÂ review of papers published since its inception
Keywords: خود را; Alzheimer's disease; Mild cognitive impairment; Amyloid; Tau; Biomarker;
Role of the Extended MAPT Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer Disease
Keywords: خود را; Delusions; hallucinations; psychosis; Alzheimer disease; MAPT; tau;
Elevated levels of cerebrospinal fluid neuron-specific enolase (NSE) in Alzheimer's disease
Keywords: خود را; Alzheimer's disease; Cerebrospinal fluid; Major depressive disorder; Neuron-specific enolase; NSE; Tau;
Searches for charged Higgs bosons, supersymmetry, and exotica with tau leptons with the ATLAS and CMS detectors at the LHC
Keywords: خود را; ATLAS; CMS; tau; charged Higgs; supersymmetry; Zâ²; leptoquarks;
A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge
Keywords: خود را; Tau; Aggregation; Nucleation; Electron microscopy; NMR spectroscopy;
p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice
Keywords: خود را; Tau; Phosphorylated tau; Neurofibrillary tangles; Immunotherapy; Beta-amyloid; Alzheimer's disease;
Short communicationHyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice
Keywords: خود را; 5XFAD mouse; Water maze test; Spatial learning and memory; GSK-3β; Tau;
Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult
Keywords: خود را; Alzheimer's disease; Clinical trial failures; Neurotoxic soluble oligomers; Soluble ABeta amyloid; Correlation of soluble oligomers with cognitive decline; Synapses; Cognitive decline; Autopsies; Senile plaques; Interrelationship of senile plaque amyloid
Interactions between GSK3β and amyloid genes explain variance in amyloid burden
Keywords: خود را; Imaging genetics; Alzheimer's disease; Amyloid; Tau; PET; ADNI;
Short ReportCerebrospinal fluid BACE1 activity and markers of amyloid precursor protein metabolism and axonal degeneration in Alzheimer's disease
Keywords: خود را; Biomarker; Dementia; Mild cognitive impairment; Diagnosis; Prognosis; Amyloid precursor protein; Amyloid-β; Tau; Correlation;
Research ReportTau mRNA is present in axonal RNA granules and is associated with elongation factor 1A
Keywords: خود را; eEF1A; eukaryotic elongation factor 1A; DIG; digoxigenin; Tau; mRNA; Axon; eEF1A;
Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy
Keywords: خود را; LC, liquid chromatography; MS, mass spectrometry; CA1, cornu ammonis area of the hippocampus; TBS, Tris-buffered salineAlzheimer; Tau; Methylene blue
Recent advances in the study of (–)clausenamide: chemistry, biological activities and mechanism of action
Keywords: خود را; (–)Clausenamide; Enantiomers; Cognition; Alzheimer׳s disease pathology; Tau; High phosphorylation; Synaptic plasticity
Infantile postnatal exposure to lead (Pb) enhances tau expression in the cerebral cortex of aged mice: Relevance to AD
Keywords: خود را; Aging; Hyperphosphorylation; CDK5; Lead; Tau
Development of dual targeting inhibitors against aggregations of amyloid-β and tau protein
Keywords: خود را; Alzheimer's disease; Amyloid-β; Tau; Aggregation; Suzuki–Miyaura couplingDKWVOINDEURCIH-UHFFFAOYSA-N; UQOZNVGULYNSJW-LFIBNONCSA-N
Rapamycin Treatment of Healthy Pigs Subjected to Acute Myocardial Ischemia-Reperfusion Injury Attenuates Cardiac Functions and Increases Myocardial Necrosis
Keywords: خود را; AAR; Area at risk; ADP; adenosine diphosphate; AKT; Protein kinase B; ANOVA; Analysis of variance; cTnI; Cardiac troponin I; dP/dT Max; left ventricular maximum contractility; dV/dT max; Left ventricular maximum filling; ECL; Enhanced chemiluminescense; E
Increased pro-nerve growth factor and decreased brain-derived neurotrophic factor in non-Alzheimer's disease tauopathies
Keywords: خود را; Alzheimer's disease; Tauopathy; Tau; Neurotrophin; Nerve growth factor; Brain-derived neurotrophic factor; Pick's disease; Corticobasal degeneration; Progressive supranuclear palsy; Post mortem brain;
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status
Keywords: خود را; Tau; High-fat diet; Alzheimer’s disease; Type 2 diabetes; Alternative splicing
Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment
Keywords: خود را; Alzheimer's disease; Dementia with Lewy bodies; Parkinson's disease with dementia; Synaptic dysfunction; Zinc; Amyloid β; Tau; Cognitive impairment;
Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia
Keywords: خود را; Frontotemporal dementia; Tau; Tauopathy; Amygdala; Neurodegeneration;