Keywords: KP; kynurenine pathway; IDO; indoleamine 2,3-dioxygenase; TDO2; tryptophan 2,3 dioxygenase (gene); TDO; tryptophan 2,3 dioxygenase (enzyme); KAT; kynurenine aminotransferase; KMO; kynurenine monooxigenase; Trp; tryptophan; KYN; L-kynurenine; KYNA; kynuren
مقالات ISI (ترجمه نشده)
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Keywords: HC; healthy controls; MDD; major depressive disorder; SOD; severity of depression; SCID; Structured Clinical Interview for DSM-IV-TR; BDI-II; Beck Depression Inventory-Second Edition; LC-MS; liquid chromatography-mass spectrometry; Total-C; total-choleste
Keywords: Immune escape; Crystal structures; IDO1 inhibitors; Cancer immunotherapy; KP; kynurenine pathway; Trp; tryptophan; KYN; kynurenine; IDO1; indoleamine 2,3-dioxygenase 1; IDO2; indoleamine 2,3-dioxygenase 2; TDO; tryptophan 2,3-dioxygenase; IFN; interferon;
Keywords: Kynurenic acid; Schizophrenia; Cognition; Alpha 7 nicotinic receptor; Choline; KP; Kynurenine pathway; CNS; central nervous system; IDO; indoleamine-2,3-dioxygenase; TDO; tryptophan-2,3-dioxygenase; KAT; kynurenine aminotransferase; KYNA; kynurenic acid;
Keywords: G-M-B; Gut-Microbiome-Brain; CNS; Central nervous system; HPA; Hypothalamic pituitary adrenal axis; IL; Interleukin; TNF; Tumor necrosis factor; LPS; Lipopolysaccharide; IDO; Indoleamine-2, 3-dioxygenase; TDO; Tryptophan 2, 3-dioxygenase; IFN; Interferon;
Keywords: Diet; Amino Acid; Kynurenine; Inflammation; Anti-Inflammatory; AHR; aryl hydrocarbon receptor; AUC; area under the curve; CAI; Clinical Activity Index for Ulcerative Colitis; CARD9; caspase recruitment domain family member 9; CD; Crohn's disease; CDAI;
Keywords: Cancer immunity; Glioma; Treg; TDO; Immunosuppression; Tryptophan;
Keywords: dermatophytes; fractional laser; onychomycosis; topical therapy; CO2; carbon dioxide; DLSO; distal lateral subungual onychomycosis; KOH; potassium hydroxide; Nd:YAG; neodymium:yttrium-aluminium-garnet; PSO; proximal subungual onychomycosis; SCIO; Scoring
Keywords: 3-HAO; 3-hydroxyanthranilic acid dioxygenase; 3-HK; 3-hydroxykynurenine; 5-HT; serotonin; IDO; indoleamine 2,3-dioxygenase; KATs; kynurenine aminotransferases; KMO; kynurenine 3-monooxygenase; KYNA; kynurenic acid; KYNU; kynureninase; QUIN; quinolinic aci
Keywords: CNS; central nervous system; ENS; enteric nervous system; BBB; blood-brain-barrier; 5-HTP; 5-hydroxytryptophan; TPH; tryptophan hydroxylase; TDO; tryptophan-2,3-dioxygenase; IDO; indoleamine-2,3-dioxygenase; AAAD; aromatic amino acid decarboxylase; NMDA;
Keywords: TDO; human tryptophan 2,3-dioxygenase; IDO; human indoleamine 2,3-dioxygenase; KMO; kynurenine 3-monoxygenase; NCI; National Cancer Institute USA; Tryptophan 2,3-dioxygenase; Cancer; Kynurenine pathway;
Keywords: MDD; major depressive disorder; BD; bipolar disorder; ASA; acetyl-salicylic acid; WHO; World Health Organization; TCAs; tricyclic antidepressants; MAOIs; monoamine oxidase inhibitors; SSRIs; selective serotonin reuptake inhibitors; PAMPs; pathogen associa
The molecular aspects of oxidative & nitrosative stress and the tryptophan catabolites pathway (TRYCATs) as potential causes of depression
Keywords: BDNF; brain-derived neurotrophic factor; CAT; catalase; CIRS; compensatory (anti)inflammatory reflex system; CoQ10; coenzyme Q10; DD; depressive disorders; GPx; glutathione peroxidise; GR; glutathione reductase; GSH; glutathione; HDL-c; high-density lipop
Suppression of a tomato SEPALLATA MADS-box gene, SlCMB1, generates altered inflorescence architecture and enlarged sepals
Keywords: AN; ANANTHA; AP1; APETALA1; AP2a; APETALA2a; BL; BLIND; CAL; CAULIFLOWER; CEN; CENTRORADIALIS; DDO; SD medium without Leu and Trp; FA; FALSIFLORA; FL; flowers at anthesis; FM; floral meristems; GAs; gibberellins; GA2ox1; GA2-oxidases 1; GA20oxs; GA20-oxid
Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition
Keywords: Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure
Regular ArticleHypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency
Keywords: TDO; tryptophan 2,3-dioxygenase; ITC; isothermal titration calorimetry; l-Trp; l-tryptophan; 5-HIAA; 5-hydroxyindoleacetic acid; αMTrp; α-methyltryptophan; Hypertryptophanemia; Hyperserotoninemia; Tryptophan 2,3-dioxygenase; TDO2;
L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences
Keywords: Kynurenine pathway; Indoleamine 2,3-dioxygenase; Kynurenine 3-monooxygenase; Kynurenine aminotransferase; Kynurenine; Kynurenic acid; Quinolinic acid; TRP; l-tryptophan; KP; kynurenine pathway; NAD+; nicotinamide adenine nucleotide; TDO; tryptophan 2,3-di
Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice
Keywords: Stress; Ido; Tdo; Kynurenine; Astrocyte; Liver;
Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors
Keywords: Indoleamine 2; 3-dioxygenase 2; IDO2 bioassay system; IDO2 inhibitor; Tryptanthrin derivatives; hIDO2; human indoleamine 2, 3-dioxygenase 2; IDO1; indoleamine 2, 3-dioxygenase 1; L-1-MT; L-1-methyl-tryptophan; TDO; tryptophan 2, 3-dioxygenase; LLC; Lewis
LC/MS-based metabolomics strategy to assess the amelioration effects of ginseng total saponins on memory deficiency induced by simulated microgravity
Keywords: Ach; acetylcholine; AD; Alzheimer's disease; Asn; asparagine; Asp; aspartic acid; BC; behavioral research control group; BH; behavioral research HU group; BHG; behavioral research HU plus GTS treatment group; CORT; corticosterone; DA; dopamine; DHBA; dihy
Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction
Keywords: BPnd; non-displacable binding potential; CG; cingulate cortex; CP; caudate putamen; CT; computed tomography; Ctrl; control; Ctrl-PBO; placebo-treated control cohort; Ctrl-NAc; NAc-treated control cohort; FOV; field of view; GSH; glutathion; HC; hippocampu
Nitrobenzofurazan derivatives of Nâ²-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1
Keywords: Nâ²-hydroxyamidines; Mechanism-based drug design; IDO1 inhibition; High selectivity; Low cytotoxicity; IDO1; indoleamine 2,3-dioxygenase 1; TDO; tryptophan 2,3-dioxygenase; L-Trp; L-tryptophan; HTS; High throughput screening; UV-Vis; ultraviolet-visi
Formation of fluorophores from the kynurenine pathway metabolite N-formylkynurenine and cyclic amines involves transamidation and carbon-carbon bond formation at the 2-position of the amine
Keywords: 2-MePIP; (2-methylpiperidine); 3-MePIP; (3-methylpiperidine); 4-MePIP; (4-methylpiperidine); AZP; (azepane); DEA; (diethylamine); DMP; (cis-2,6-dimethylpiperidine); DPA; (dipropylamine); HRMS; (high-resolution mass spectrometry); IDO1; (indoleamine 2,3-di
Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells
Keywords: IFN; interferon; IDO; indoleamine 2,3-dioxygenase; TDO; tryptophan dioxygenase; HPRT; hypoxanthine/guanine phosphoribosyl transferase; SLC; solute-linked carrier; LAT; l-amino acid transporter; PAT; proton-coupled amino acid transporter; MCT; monocarboxyl
Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine
Keywords: aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CED; Cambridge Electronic Design; DCX; doublecortin; DISC1; Disrupted in Schizophrenia-1; fEPSPs; field excitatory postsynaptic potentials; HRP; horseradish peroxidase; IDO; indolamine-2,3
Biosynthesis of N,N-dimethyltryptamine (DMT) in a melanoma cell line and its metabolization by peroxidases
Keywords: AFMK; N-acetyl-N-formyl-5-methoxy-kynuramine; AMK; N-acetyl-5-metoxy-kynuramine; DMEM; Dulbecco' modified eagle medium; DMFK; N,N-dimethyl-N-formyl-kynuramine; DMK; N,N-dimethyl-quinuramine; DMSO; dimethyl sulfoxide; DMT; N,N-dimethyltryptamine; DPI; di
Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A
Keywords: IDO1; indoleamine 2,3-dioxygenase; TDO; tryptophan 2,3-dioxygenase; NHDF; normal fibroblast cell lines; MTT; (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; EDTA; ethylenediaminetetraacetic acid; IMAC; immobilized metal ion affinity chromat
Effect of systemic kynurenine on cortical spreading depression and its modulation by sex hormones in rat
Keywords: CSD; cortical spreading depression; DC; direct current; FHM; familial hemiplegic migraine; HPLC; high performance liquid chromatography; IDO; indoleamine 2,3-dioxygenase; KAT; kynurenine aminotransferases; KYNA; Kynurenic acid; L-KYN; l-kynurenine; nAChR;
Citalopram decreases tryptophan 2,3-dioxygenase activity and brain 5-HT turnover in swim stressed rats
Keywords: Citalopram; swim stress; serotonin; corticosterone; TDO; 5-HT; tryptophan
Modulation of cytochrome P450 gene expression in primary hepatocytes on various artificial extracellular matrices
Keywords: ASGPR; asialoglycoprotein receptor; BAL; bioartificial liver; BSA; bovine serum albumin; CYP; cytochrome P450; DAPI; 4â²,6-diamidino-2-phenylindole; E-cad-Fc; E-cadherin-IgG Fc; ECM; extracellular matrix; EGF; epidermal growth factor; Mrp2; multidrug res
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: Focus on individual differences
Keywords: UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine, 5-HT, serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; KYNA; kynurenic acid; IDO; indoleamine-2,3-dioxygenase
Processing technologies for poly(lactic acid)
Keywords: BD; 1,4-butanedial; BDI; 1,4-butane diisocyanate; DSC; differential scanning calorimetry; BUR; blow-up-ratio; ÎHrel; endothermic enthalpy relaxation; ÎHc; heat of crystallization; ÎHm; heat of fusion; HDPE; high density polyethylene; HIPS; high impact