دانلود مقالات ISI درباره ThT، Thioflavin T + ترجمه فارسی

Thermodynamic and Kinetic Characterization of a Germ Line Human λ6 Light-Chain Protein: The Relation between Unfolding and Fibrillogenesis

Keywords: ThT، Thioflavin T; GdnHCl, guanidine hydrochloride; DSC, differential scanning calorimetry; ThT, thioflavin T; PBS, phosphate-buffered salineamyloidosis; off-pathway intermediate; light chains; transition state; differential scanning calorimetry

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

At Low Concentrations, 3,4-Dihydroxyphenylacetic Acid (DOPAC) Binds Non-Covalently to α-Synuclein and Prevents Its Fibrillation

Keywords: ThT، Thioflavin T; DOPAC, 3,4-dihydroxyphenylacetic acid; α-Syn, α-synuclein; PD, Parkinson's disease; MS, mass spectrometry; ThT, thioflavin T; EM, electron microscopy; AFM, atomic force microscopy; SEC, size-exclusion chromatography; ESI, electrospray ionization; NBT, nit

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner

Keywords: ThT، Thioflavin T; α-syn, α-synuclein; DA, dopamine; PD, Parkinson's disease; EM, electron microscopy; ThT, thioflavin T; DHI, 5,6-dihydroxylindole; FTIR, Fourier transform infrared spectroscopyα-synuclein; dopamine; Parkinson's disease; amyloid; oligomer

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of the Heterogeneity and Specificity of Interpolypeptide Interactions in Amyloid Protofibrils by Measurement of Site-Specific Fluorescence Anisotropy Decay Kinetics

Keywords: ThT، Thioflavin T; 1,5-IAEDANS, 5-((((2-iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid; AFM, atomic force microscopy; ThT, thioflavin T; IRF, instrument response functionbarstar; amyloid protofibrils; time-resolved fluorescence anisotropy decay; two-population ani

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

TiO2 nanoparticles promote β-amyloid fibrillation in vitro

Keywords: ThT، Thioflavin T; AD, Alzheimer’s disease; Aβ, β-amyloid; APP, amyloid precursor protein; ApoE, apolipoprotein E; PBS, phosphate buffered saline; ThT, Thioflavin T; TEM, transmission electron microscopyAlzheimer’s disease; β-Amyloid; Fibrillation; Nanoparticle; Nanotoxicit

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Impact of Tyr to Ala mutations on α-synuclein fibrillation and structural properties

Keywords: ThT، Thioflavin T; PD, Parkinson's disease; ThT, Thioflavin T; CD, circular dichroism; ATR, attenuated total reflectanceα-synuclein; Tyr's mutant; Fibrillation; Secondary structure; ThT fluorescence assay; Long-range intramolecular interaction

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Identification and characterization of a novel fibril forming peptide in fungal starch binding domain

Keywords: ThT، Thioflavin T; GA, glucoamylase; SBD, starch-binding domain; CBM, carbohydrate binding module; CT-14, the last 14 amino acids at the C-terminal end of SBD, DNNNSANYQVSTSK; CD, circular dichroism; ThT, Thioflavin T; AFM, atomic force microscopy.Starch-binding domain; Car

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Spectroscopic evidence for the existence of an obligate pre-fibrillar oligomer during glucagon fibrillation

Keywords: ThT، Thioflavin T; Glucagon; Kinetic; Pre-fibrillar specie; Oligomer; ExcimerG, glucagon; PG, N-terminal pyrene modified glucagon; ThT, thioflavin T; DLS, dynamic light scattering; AFM, atomic force microscopy; RH, hydrodynamic radius; GdmCl, Guanidinium Chloride; FRET, För

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Prefibrillar transthyretin oligomers and cold stored native tetrameric transthyretin are cytotoxic in cell culture

Keywords: ThT، Thioflavin T; PMIA-C10A/A37C TTR, a cysteine to alanine and alanine to cysteine substituted transthyretin mutant in position 10 and 37, respectively labeled with the dye N-(1-pyrenemethyl)iodoacetamide; ThT, thioflavin T; TTR, transthyretinAmyloid; Apoptosis; Transthyr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Sequence determinants regulating fibrillation of human α-synuclein

Keywords: ThT، Thioflavin T; PD, Parkinson’s disease; ThT, thioflavin T; WT, wild-type; NAC, non-amyloid β component; CD, circular dichroismConformational switch; Protein amyloid; Protein fibrils; Protein folding; α-Synuclein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of β-amyloid peptide aggregation and neurotoxicity by α-d-mannosylglycerate, a natural extremolyte

Keywords: ThT، Thioflavin T; AD, Alzheimer's disease; MG, α-d-mannosylglycerate; Aβ, β-amyloid; MTT, 3-2,5-diphenyltetrazolium bromide; ThT, thioflavin T; AFM, atomic force microscopy; DMSO, dimethyl sulfoxide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Chiral Bifurcation in Aggregating Insulin: An Induced Circular Dichroism Study

Keywords: ThT، Thioflavin T; ThT, thioflavin T; ICD, induced circular dichroism; TEM, transmission electron microscopy; SEM, scanning electron microscopy; DMSO, dimethyl sulfoxide; FT-IR, Fourier transform infraredamyloid; protein aggregation; insulin; chirality; stochastic process

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Membrane interactions and lipid binding of casein oligomers and early aggregates

Keywords: ThT، Thioflavin T; PDA, polydiacetylene; DMPA, dimyristoylphosphatidic acid; DMPC, dimyristoylphosphatydilcholine; DMPG, dimyristoylphosphatidylglycerol; DMPS, dimyristoylphosphatidylserine; SDS, sodium dodecyl sulfate; ThT, Thioflavin T; NBD-PE, N-(7-nitrobenz-2-oxa-1,3-di

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Structural Characteristics of α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

Keywords: ThT، Thioflavin T; PD, Parkinson's disease; AFM, atomic force microscopy; SEC, size exclusion chromatography; FTIR, Fourier transform infrared spectroscopy; SAXS, small-angle X-ray scattering; EM, electron microscopy; ATR, attenuated total reflectance; ThT, thioflavin T; PA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

The Effect of Membranes on the In Vitro Fibrillation of an Amyloidogenic Light-Chain Variable-Domain SMA

Keywords: ThT، Thioflavin T; SUV, small unilamellar vesicle; LUV, large unilamellar vesicle; ATR-FTIR, attenuated total reflectance Fourier-transform infrared spectroscopy; ThT, thioflavin T; EM, electron microscopy; LC, light chain; PC, phosphatidylcholine; PE, phosphatidylethanolam

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Evidence for Stepwise Formation of Amyloid Fibrils by the Mouse Prion Protein

Keywords: ThT، Thioflavin T; moPrP, mouse prion protein; ThT, thioflavin T; SI, scattering intensity; DLS, dynamic light scattering; AFM, atomic force microscopyprotofibrils; worm-like fibrils; amyloid fibrils; mouse prion protein; protein aggregation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Kinetics of Fibril Formation of Bovine κ-Casein Indicate a Conformational Rearrangement as a Critical Step in the Process

Keywords: ThT، Thioflavin T; CMP, caseinomacropeptide; SCM, S-carboxymethylated; TEM, transmission electron microscopy; ThT, thioflavin T; TFA, trifluoroacetic acidcarboxymethylated κ-casein; O-glycosylation; fibril formation kinetics; casein inhibitors

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

β-Lactoglobulin Assembles into Amyloid through Sequential Aggregated Intermediates

Keywords: ThT، Thioflavin T; AFM, atomic force microscopy; ANS, 1-anilino-8-naphthalenesulfonate; β-LGa, β-lactoglobulin variant A; GIPG, globally regularized interior point gradient; DLS, dynamic light scattering; ThT, thioflavin T; AggA, aggregate A; AggB, aggregate B; APTES, amino

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

Synergistic action of polyanionic and non-polar cofactors in fibrillation of human islet amyloid polypeptide

Keywords: ThT، Thioflavin T; IAPP, human islet amyloid polypeptide; ThT, thioflavin T; HFIP, 1,1,1,3,3,3-hexafluoroisopropanol; TFE, 2,2,2-trifluoroethano; iPrOH, isopronanol; EtOH, ethanol; polyE, poly-l-glutamate; TEM, transmission electron microscopy; GAG, glycosaminoglycanIAPP; A

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Promotion of insulin aggregation by protein disulfide isomerase

Keywords: ThT، Thioflavin T; PDI, protein disulfide isomerase; GR, glutathione reductase; GSH, glutathione reduced form; GSSG, glutathione oxidized form; NADPH, β-nicotinamide adenine dinucleotide phosphate; ThT, thioflavin T; CR, Congo red; FT-IR, Fourier transform infraredProtein d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The Distribution of Residues in a Polypeptide Sequence Is a Determinant of Aggregation Optimized by Evolution

Keywords: ThT، Thioflavin T; apoMb, horse heart apomyoglobin; CD, circular dichroism; FTIR, Fourier transform infrared; SD, standard deviation; SE, standard error; ThT, thioflavin T; UV, ultraviolet; WT, wild-type

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Oxidation reduces the fibrillation but not the neurotoxicity of the prion peptide PrP106–126

Keywords: ThT، Thioflavin T; TSE, Transmissible spongiform encephalopathy; MetO, Methionine sulfoxide; ERG, Electroretinography; PK, Proteinase K; ThT, Thioflavin T; TUNEL, Terminal dUTP nick end labeling; EM, Electron microscopy; wt, Wild typePrion peptide; Oxidation; Electroretinog

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Serpin Acceleration of Amyloid Fibril Formation: A Role for Accessory Proteins

Keywords: ThT، Thioflavin T; AD, Alzheimer's disease; ACT, antichymotrypsin; RCL, reactive center loop; apoC-II, apolipoprotein C-II; α1AT, α1-antitrypsin; ThT, thioflavin T; TEM, transmission electron microscopyfibrillogenesis; protein aggregation; antichymotrypsin; serpin; conforma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Kinetic Refolding Barrier of Guanidinium Chloride Denatured Goose δ-Crystallin Leads to Regular Aggregate Formation

Keywords: ThT، Thioflavin T; ASL, argininosuccinate lyase; ANS, 1-anilinonaphthalene-8-sulfonic acid; GdmCl, guanidinium hydrochloride; N-25, deletion of 25 residues from the N-terminus of goose δ-crystallin; ThT, thioflavin T; CR, Congo red; TEM, transmission electron microscopy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Conformational Properties of Aggregated Polypeptides Determine ClpB-dependence in the Disaggregation Process

Keywords: ThT، Thioflavin T; GuHCl, guanidine hydrochloride; ThT, thioflavin T; EM, electron microscopy; KJE, DnaK/DnaJ/GrpEchaperone-dependent protein disaggregation; ClpB; Hsp70; protein aggregation; luciferase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways

Keywords: ThT، Thioflavin T; EtOH, ethanol; ThT, thioflavin T; MTT, [4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; ANS, 1-anilinonaphthalene-8-sulfonic acid; AFM, atomic force microscopy; DLS, dynamic light scattering; FTIR, Fourier transform infrared; D, deuterium; IAPP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity

Keywords: ThT، Thioflavin T; PD, Parkinson's disease; α-syn, α-synuclein; scFv, single chain antibody fragment; AFM, atomic force microscope; NAC, non-amyloid component; A30P, human A30P α-synuclein; A53T, human A53T α-synuclein; E46K, human E46K α-synuclein; ThT, Thioflavin T; GAG,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Relationships between the Sequence of α-Synuclein and its Membrane Affinity, Fibrillization Propensity, and Yeast Toxicity

Keywords: ThT، Thioflavin T; PD, Parkinson's disease; wt, wild-type; ThT, thioflavin T; GFP, green fluorescent proteinsynuclein; Parkinson's disease; fibrillization; membrane binding; yeast toxicity

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

A Structural Core Within Apolipoprotein C-II Amyloid Fibrils Identified Using Hydrogen Exchange and Proteolysis

Keywords: ThT، Thioflavin T; apo, apolipoprotein; LDL, low-density lipoproteins; H/D, hydrogen/deuterium; d6-DMSO, d6-dimethyl sulfoxide; d2-DCA, d2-dichloroacetic acid; ThT, Thioflavin T; TFA, trifluoroacetic acid; IAPP, islet amyloid polypeptide; HSQC, heteronuclear single quantum

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Characterisation of Amyloid Fibril Formation by Small Heat-shock Chaperone Proteins Human αA-, αB- and R120G αB-Crystallins

Keywords: ThT، Thioflavin T; DRM, desmin-related myopathy; sHsp, small heat shock protein; TEM, transmission electron microscopy; AFM, atomic force microscopy; ThT, Thioflavin T; CR, Congo red; GdnHCl, guanidine hydrochloride; TFE, trifluoroethanolamyloid; fibrils; αB-crystallin; αA-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Kinetics of amyloid aggregation of mammal apomyoglobins and correlation with their amino acid sequences

Keywords: ThT، Thioflavin T; ThT, Thioflavin T; Mb, myoglobinProtein aggregation rate; Apomyoglobin aggregation; Amyloid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Fibrillogenic and Non-fibrillogenic Ensembles of SDS-bound Human α-Synuclein

Keywords: ThT، Thioflavin T; SDS, sodium dodecyl sulfate; bis-ANS, 1,1′-bis (4-anilino) naphthalene-5,5′-disulfonic acid; ThT, thioflavin T; ITC, isothermal calorimetryα-synuclein; SDS; Parkinson's disease; amyloid; isothermal titration calorimetry

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

The Oxidation State of DJ-1 Regulates its Chaperone Activity Toward α-Synuclein

Keywords: ThT، Thioflavin T; Parkinson's disease; DJ-1; α-synuclein; fibrillation; aggregationPD, Parkinson's disease; MS, mass spectrometry; ThT, thioflavin T; EM, electron microscopy; FTIR, Fourier transform infrared; SEC, size-exclusion chromatography

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Oleic Acid Inhibits Amyloid Formation of the Intermediate of α-Lactalbumin at Moderately Acidic pH

Keywords: ThT، Thioflavin T; apo-BLA, Ca2+-depleted bovine α-lactalbumin; α-LA, α-lactalbumin; AFM, atomic force microscopy; CR, Congo red; HAMLET, human α-lactalbumin made lethal to tumor cells; MG, molten globule; TEM, transmission electron microscopy; ThT, thioflavin T; ANS, 8-ani

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Heat Shock Protein 70 Inhibits α-Synuclein Fibril Formation via Interactions with Diverse Intermediates

Keywords: ThT، Thioflavin T; AS, α-synuclein; Hsp, heat shock protein; PreAS, prefibrillar AS; PD, Parkinson's disease; Hsp70s, heat shock protein 70 family members; polyQ, polyglutamine; ThT, Thioflavin T; EM, electron microscopyα-synuclein; fibril; intermediate; heat shock protein

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

A Molecular Dynamics Approach to the Structural Characterization of Amyloid Aggregation

Keywords: ThT، Thioflavin T; amyloid; Alzhemer's disease; prion; protein aggregation; site-directed mutagenesisMD, molecular dynamics; APP, amyloid precursor protein; REMD, replica exchange MD; ThT, thioflavin T; EPR, electron paramagnetic resonance; SS, secondary structure; hIAPP, h

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

The Changing Face of Glucagon Fibrillation: Structural Polymorphism and Conformational Imprinting

Keywords: ThT، Thioflavin T; glucagons; fibrillation; polymorphism; kinetics; imprintingEM, electron microscopy; AFM, atomic force microscopy; ThT, thioflavin T; CD, circular dichroism; ATR-FTIR, attenuated total reflection Fourier transformed infra red; IS, internal scissions; HN, h

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2006 سفارش ترجمه

Evidence for p62 aggregate formation: Role in cell survival

Keywords: ThT، Thioflavin T; AD, Alzheimer’s disease; GST, glutathione S-transferase; FTIR, Fourier transform infrared; ThT, Thioflavin T; HEK, human embryonic kidney; NF-κB, nuclear factor κB; UBA, ubiquitin associated; PB1, Phox and Bem1p; UPS, ubiquitin–proteasome system; LB, Lewy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه