Taxanes inhibit human TLR4 signaling by binding to MD-2
Keywords: گیرنده تله مانند 4; Paclitaxel; Docetaxel; MD-2; Lipopolysaccharide; Toll-like receptor 4
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Increased expression and internalization of the endotoxin coreceptor CD14 in enterocytes occur as an early event in the development of experimental necrotizing enterocolitis
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Lipopolysaccharide; Bacterial translocation; Hypoxic stress; Critical illness
n-3 PUFA attenuate lipopolysaccharide-induced down-regulation of toll-like receptor 4 expression in porcine adipose tissue but does not alter the expression of other immune modulators
Keywords: گیرنده تله مانند 4; Pig; n-3 Polyunsaturated fatty acids; Lipopolysaccharide; Inflammation; Toll-like receptor 4
Hantaan virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon, interleukin-6 and tumor necrosis factor-alpha
Keywords: گیرنده تله مانند 4; Hantaan virus; Toll-like receptor 4; IL-6; IFN-β; TNF-α
Human Immunodeficiency Virus-Related Microbial Translocation and Progression of Hepatitis C
Keywords: گیرنده تله مانند 4; AAL; Aleuria aurantia fucose-binding lectin; EndoCAb IgM; anti-LPS immunoglobulin M; LBP; LPS-binding protein; LPS; lipopolysaccharide; TLR4; Toll-like receptor 4; TNF-α; tumor necrosis factor α; sCD14; soluble CD14;
Rapamycin suppresses TLR4-triggered IL-6 and PGE2 production of colon cancer cells by inhibiting TLR4 expression and NF-κB activation
Keywords: گیرنده تله مانند 4; Rapamycin; Toll-like receptor 4; Colon cancer; NF-κB; Interleukin-6; Prostaglandin E2
Gene expression profiling reveals upregulation of Tlr4 receptors in Cckb receptor deficient mice
Keywords: گیرنده تله مانند 4; Cholecystokinin B receptor; Toll-like receptor 4; Chronic constriction injury; Gene expression profiling; Microarrays
Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells
Keywords: گیرنده تله مانند 4; Endotoxin; Glycine; Kupffer cell; Liver injury; Signal transduction; Toll-like receptor 4
Vasoactive intestinal peptide suppresses toll-like receptor 4 expression in macrophages via Akt1 reducing their responsiveness to lipopolysaccharide
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Akt; Inflammation; Vasoactive intestinal peptide; Lipopolysaccharide
μ-Opioid agonists inhibit the enhanced intracellular Ca2+ responses in inflammatory activated astrocytes co-cultured with brain endothelial cells
Keywords: گیرنده تله مانند 4; astrocyte; calcium; endothelial cells; inflammatory activators; opioids; pain-transmitting peptides; BBB; blood-brain barrier; BSA; bovine serum albumin; [Ca2+]i; intracellular free calcium; CGRP; calcitonin gene-related peptide; DAMGO; [d-Ala2,NMe-Phe4
Genetic background of IL-10−/− mice alters host–pathogen interactions with Campylobacter jejuni and influences disease phenotype
Keywords: گیرنده تله مانند 4; Campylobacter jejuni; Enteritis; Murine disease model; IL-10; Toll-like receptor 4; Cytokine deficiency-induced colitis susceptibility 1 (Cdcs1) allele; Inflammatory bowel disease
Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles
Keywords: گیرنده تله مانند 4; Hydroxyapatite particles; Cytokines; Inflammation; Toll-like receptor 4; Macrophages
Lipopolysaccharide regulates toll-like receptor 4 expression in human aortic smooth muscle cells
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Lipopolysaccharide; Smooth muscle cell;
LPS Induces Translocation of TLR4 in Amniotic Epithelium
Keywords: گیرنده تله مانند 4; Placenta; Toll-like receptor 4; Amnion; Amniotic epithelium; Chorioamnionitis lipopolysaccharide; Translocation
Reduced cerebral ischemia-reperfusion injury in Toll-like receptor 4 deficient mice
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Cerebral ischemia/reperfusion; Inflammatory factor; Stroke
Fever range temperature promotes TLR4 expression and signaling in dendritic cells
Keywords: گیرنده تله مانند 4; Fever; Toll-like receptor 4; Signal transduction; Dendritic cells; Cytokine
Expression of Toll-like receptor 4 in the basilar artery after experimental subarachnoid hemorrhage in rabbits: A preliminary study
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Inflammation; Cerebral vasospasm; Subarachnoid hemorrhage
Toll-like receptor 4 signal transduction inhibitor, M62812, suppresses endothelial cell and leukocyte activation and prevents lethal septic shock in mice
Keywords: گیرنده تله مانند 4; Sepsis; Toll-like receptor 4; Lipopolysaccharide
The cellular Toll-like receptor 4 antagonist E5531 can act as an agonist in horse whole blood
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; E5531; Horse; Macrophage; Whole blood assay; Lipopolysaccharide
Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model
Keywords: گیرنده تله مانند 4; TAK-242; Toll-like receptor 4; Endotoxin shock; Cytokine; Nitric oxide; (Mouse)
Toll-like receptor 4 siRNA attenuates LPS-induced secretion of inflammatory cytokines and chemokines by macrophages
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; siRNA; Lipopolysaccharides; Macrophage; Inhibition
Kinetics of Toll-like receptor-4 splice variants expression in lipopolysaccharide-stimulated antigen presenting cells of healthy donors and patients with cystic fibrosis
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Alternative splicing; Cystic fibrosisTLR4, Toll-like receptor 4; LPS, lipopolysaccharide; TNF, tumor necrosis factor; CF, cystic fibrosis; APC, antigen presenting cells; PAMP, pathogen-associated molecular patterns; RQ-PCR, real-time
Interleukin-1 is not essential for expression of inducible NOS in hepatocytes induced by lipopolysaccharide in vivo
Keywords: گیرنده تله مانند 4; Interleukin-1; Knockout mice; Kupffer cells; Lipopolysaccharide; Nitric oxide; Toll-like receptor 4; Tumor necrosis factor α;
Hyperexpression of FcγRI and Toll-like receptor 4 in the intestinal mast cells of Crohn’s disease patients
Keywords: گیرنده تله مانند 4; Crohn’s disease; Mast cells; FcγRI; Toll-like receptor 4; Tumor necrosis factor-α
Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4
Keywords: گیرنده تله مانند 4; Angelica gigas Nakai; Angelan; Polysaccharides; Dendritic cells; Toll-like receptor 4
Protein-energy malnutrition decreases the expression of TLR-4/MD-2 and CD14 receptors in peritoneal macrophages and reduces the synthesis of TNF-α in response to lipopolysaccharide (LPS) in mice
Keywords: گیرنده تله مانند 4; Cytokines; LPS; Macrophage; Toll-like receptor 4; CD14; Protein-energy malnutrition
Extracellular Superoxide Production by Enterococcus faecalis Promotes Chromosomal Instability in Mammalian Cells
Keywords: گیرنده تله مانند 4; γ-CEHC; γ-carboxyethyl-hydroxychroman; CIN; chromosomal instability; COX-2; cyclooxygenase-2; MOI; multiplicity of infection; αT; α-tocopherol; γT; γ-tocopherol; TLR4; Toll-like receptor 4;
C1 inhibitor: Biologic activities that are independent of protease inhibition
Keywords: گیرنده تله مانند 4; C1 inhibitor; Cecal ligation and puncture model; Endotoxin shock; Gram negative bacterial sepsis; Selectins; Serine proteinase inhibitors; CEA; carcinoembryonic antigen; CLP; cecal ligation and puncture; LBP; LPS-binding protein; LPS; lipopolysaccharide;
Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: Acute renal failure is dependent on MyD88 but not renal cell apoptosis
Keywords: گیرنده تله مانند 4; acute renal failure; sepsis; MyD88; innate immunity; toll-like receptor 4
Effect of herbal melanin on IL-8: A possible role of Toll-like receptor 4 (TLR4)
Keywords: گیرنده تله مانند 4; Herbal melanin; Toll-like receptor 4; Nigella sativa L; IL-8; Lipopolysaccharide; MD2; CD14
Ligand-independent oligomerization of TLR4 regulated by a short hydrophobic region adjacent to the transmembrane domain
Keywords: گیرنده تله مانند 4; Oligomerization; Short hydrophobic region; Toll-like receptor 4
A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Cell surface molecules; Lipopolysaccharide; Innate immunity
Role of astrocytic S100β in behavioral hypersensitivity in rodent models of neuropathic pain
Keywords: گیرنده تله مانند 4; astrocytes; chronic pain; glia; glial fibrillary acidic protein; mechanical allodynia; AGE; advanced glycation end product; CFA; complete Freund's adjuvant; COX-2; Cyclooxygenase 2; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; glial fibrillary
Association of Toll-Like Receptor 4 Polymorphisms with Somatic Cell Score and Lactation Persistency in Holstein Bulls
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; health trait; somatic cell score; Canadian Holstein;
Differential expression of the CD14/TLR4 complex and inflammatory signaling molecules following i.c.v. administration of LPS
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; CD14; Apoptosis; Tissue injury; Neuroinflammation; Neuroprotection
Sexual dimorphism in expression of receptors for bacterial lipopolysaccharides in murine macrophages: A possible mechanism for gender-based differences in endotoxic shock susceptibility
Keywords: گیرنده تله مانند 4; Sexual dimorphism; Sepsis; Monocytes/macrophages; Toll-like receptor 4; CD14; Inflammation
Novel pathway for LPS-induced afferent vagus nerve activation: Possible role of nodose ganglion
Keywords: گیرنده تله مانند 4; IL-1β; Interleukin-1β; LPS; Lipopolysaccharide; HPA axis; Hypothalamic-pituitary-adrenal axis; Afferent vagus nerve; Immune-to-brain communication; Toll-like receptor 4; Nodose ganglion;
Toll-like receptor 4 (TLR4) plays a relatively minor role in murine defense against primary intradermal infection with Francisella tularensis LVS
Keywords: گیرنده تله مانند 4; Francisella tularensis; Toll-like receptor 4; Pathogenesis; Mouse model;
Toll-like receptor 4 gene C119A but not Asp299Gly polymorphism is associated with ischemic stroke among ethnic Chinese in Taiwan
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Atherosclerosis; Asp299Gly;
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; TLR-4; Polymorphism; Multiple sclerosis;
Perspectives on the past decade of asthma genetics
Keywords: گیرنده تله مانند 4; Asthma; allergy; genetics; gene-by-environment interactions; AD; Atopic dermatitis; ADRB2; β2-Adrenergic receptor; CD14; Monocyte differentiation antigen 14; COAST; Childhood Onset of Asthma Study; FCERB1; FcÉRβ1; GSTM1; Glutathione S-transferase M1; G
Placental vascular disease and toll-like receptor 4 gene expression
Keywords: گیرنده تله مانند 4; Placental vascular disease; Toll-like receptor 4; Innate immunity; Doppler ultrasound;
Selective suppression of Toll-like receptor 4 activation by chemokine receptor 4
Keywords: گیرنده تله مانند 4; TLR; Toll-like receptor; CXCR4; chemokine receptor 4; LPS; lipopolysaccharide; SDF-1; stromal-cell derived factor-1; NFκB; nuclear factor kappa B; SLPI; secretory leucoprotease inhibitor; HSP; heat shock protein; Lipopolysaccharide; Toll-like receptor 4;
Down-regulatory effect of quercitrin gallate on nuclear factor-κB-dependent inducible nitric oxide synthase expression in lipopolysaccharide-stimulated macrophages RAW 264.7
Keywords: گیرنده تله مانند 4; IκB; inhibitory κB; IKK; inhibitory κB kinase; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NF-κB; nuclear factor-κB; NO; nitric oxide; PDTC; pyrrolidine dithiocarbamate; QGR; quercetin 3-O-β-(2â³-galloyl)-rhamnopyranoside; SEAP;
Infant home endotoxin is associated with reduced allergen-stimulated lymphocyte proliferation and IL-13 production in childhood
Keywords: گیرنده تله مانند 4; Endotoxin; lymphocyte proliferation; cytokine; childhood; allergy; EU; Endotoxin units; OR; Odds ratio; SI; Stimulation index; TLR4; Toll-like receptor 4;
Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis
Keywords: گیرنده تله مانند 4; Bile duct epithelial cells; Lipopolysaccharide; Primary biliary cirrhosis; Toll-like receptor 4;
The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (α-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages
Keywords: گیرنده تله مانند 4; Alpha-melanocyte-stimulating hormone; Toll-Like receptor 4; Interleukin-1 receptor-associated kinase-M; Macrophages;
Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances TH2 development
Keywords: گیرنده تله مانند 4; Human respiratory tract; dendritic cells; GM-CSF; TH1/TH2; DC; Dendritic cell; MLR; Mixed lymphocyte reaction; PBDC; Peripheral blood dendritic cell; RTDC; Respiratory tract dendritic cell; TLR4; Toll-like receptor 4; UK; United Kingdom;
Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells
Keywords: گیرنده تله مانند 4; Toll-like receptor 4; Lipopolysaccharide; CD14; Caveolae; Endocytosis; Chinese hamster ovary cells; MD-2;
Inhibition of Cell Proliferation by Bacterial Lipopolysaccharides in TLR4-Positive Epithelial Cells: Independence of Nitric Oxide and Cytokine Release
Keywords: گیرنده تله مانند 4; epidermis; innate immune defense; LPS; nitric oxide synthase; toll-like receptor 4;