Use of Self-expanding Intracranial Stents in the Treatment of Acute Ischemic Stroke
Keywords: MCA; middle cerebral artery; TPA; tissue plasminogen activator;
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Tunneled Pleural Catheters for Treatment of Recurrent Malignant Pleural Effusion Following Failed Pleurodesis
Keywords: tPA; tissue-type plasminogen activator;
Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells
Keywords: Alpha-synuclein; Monomer; Aggregate; MMP-9; tPA;
Optimizing thrombelastography (TEG) assay conditions to monitor rFVIIa (NovoSeven®) therapy in haemophilia a patients
Keywords: TEG; Thromboelastography; rFVIIa; recombinant Factor VIIa; FVIII; Factor VIII; FIX; Factor IX; FX; Factor X; tPA; tissue plaminogen activator; TF; tissue factor; R-time; Reaction time; MTG; maximum thrombus generation; MA; maximum amplitude; pd-aPCC; acti
Efficacy of Local Instillation of Recombinant Tissue Plasminogen Activator for Restoring Occluded Central Venous Catheters in Neonates
Keywords: CVC; Central venous catheter; GA; Gestational age; HSC; Hospital for Sick Children; IQR; Interquartile range; NICU; Neonatal intensive care unit; PTT; Partial thromboplastin time; tPA; Tissue plasminogen activator; TPN; Total parenteral nutrition;
Transcription factor AP1 modulates the internal promoter activity of bovine foamy virus
Keywords: Bovine foamy virus (BFV); AP1; TPA
Long-term stability of fibrinolytic factors stored at -80 °C
Keywords: tPA; tissue plasminogen activator; PAI-1; plasminogen activator inhibitor 1; NSHDS; Northern Sweden Health and Disease Study; VIP; Västerbotten Intervention Programme; WHO-MONICA; World Health Organisation- Monitoring Trends and Determinants in Cardiovas
Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model
Keywords: TPA, 12-O-tetradecanoylphorbol 13-acetate; TNFα, Tumor necrosis factor alpha; PKC, Protein kinase CHaCat; Pam212; TPA; TNFα; Keratinocytes; Genomics; MAPK signalling
12-O-Tetradecanoyl phorbol-13-acetate (TPA)-induced growth arrest is increased by silibinin by the down-regulation of cyclin B1 and cdc2 and the up-regulation of p21 expression in MDA-MB231 human breast cancer cells
Keywords: Silibinin; Silybum marianum; TPA; Cyclin B1; Cdc2; p21
The effects of IL-32 on the inflammatory activation of cultured rat primary astrocytes
Keywords: IL-32; iNOS; MMP-9; tPA; Inflammatory responses; Astrocyte
Antioxidant and antimicrobial properties of Moltkia petraea (Tratt.) Griseb. flower, leaf and stem infusions
Keywords: ASC; ascorbic acid; BHA; butylated hydroxyanisol; ChA; chelating activity; DPPH; 2,2-diphenyl-1-picrylhydrazyl; ROS; reactive oxygen species; RSA; free radical scavenging activity; TF; total flavonoid content; TP; total phenol content; TPA; total phenolic
Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice
Keywords: Inflammation; MAPK; PEP-1-rpS3; TPA;
The mechanism of HTLV-1 LTR activation by TPA varies in different human T-cell lines: Role of specific PKC isoforms
Keywords: HTLV-1 LTR; 21Â bp TRE; ERR-1; Sp1 site; TPA; PKC isoforms; Jurkat and H9 T-cell lines;
Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease
Keywords: Extra-cellular matrix; Heart remodeling; Acute kidney injury; Fibrosis; Epithelial to mesenchymal transition; Endothelial to mesenchymal transition; Integrin; tPA; PAI-1; Transforming growth factor beta
Long-term Outcomes of Low-dose Catheter-directed Thrombolytic Therapy: A 5-year Single-center Experience
Keywords: tPA; tissue-type plasminogen activator;
Validation of an in vitro screening test for predicting the tumor promoting potential of chemicals based on gene expression
Keywords: TPA; 12-O-Tetradecanoylphorbol-13-acetate; MeIQ; 2-amino-3,4-dimethylimidazo[4,5-f]quinoline; PhIP; 2-amino-1-methyl-6-phenylimidazo(4,5-B)pyridine; In vitro screening; Molecular marker; Transformation assay; Tumor promoter; Genotoxicity; Carcinogen;
Provocative Mesenteric Angiography for Lower Gastrointestinal Hemorrhage: Results from a Single-institution Study
Keywords: GI; gastrointestinal; IMA; inferior mesenteric artery; RBC; red blood cell; SMA; superior mesenteric artery; TPA; tissue plasminogen activator;
Experimental and theoretical study of a new carbazole derivative having terminal benzimidazole rings
Keywords: Benzimidazole; Carbazole; Fluorescence; TDDFT; TPA
Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPAâ/â) mice
Keywords: tPA; Serotonin; Mouse; Disinhibition; Impulsivity;
Regulation of tumor suppressor PDCD4 by novel protein kinase C isoforms
Keywords: PDCD4; Novel PKC; TPA; Hepatocellular carcinoma
The inhibitory effect of hesperidin on tumor cell invasiveness occurs via suppression of activator protein 1 and nuclear factor-kappaB in human hepatocellular carcinoma cells
Keywords: Hesperidin; TPA; Matrix metalloproteinase-9; Tumor invasion; Nuclear factor-κB; Activator protein 1
Cathepsin G: Roles in antigen presentation and beyond
Keywords: AEP; asparagine endopeptidase; APC; antigen presenting cell; BLC; B lymphoblastoid cells; Cat; cathepsin; CCL15; chemokine (C-C motif) ligand 15; CLIP; class II-associated Ii peptides; cTEC; cortical thymic epithelial cells; CXCL5; chemokine (C-X-C
Breast cancer cell surface annexin II induces cell migration and neoangiogenesis via tPA dependent plasmin generation
Keywords: Plasmin; Annexin II; Breast cancer; Neoangiogenesis; tPA
Short-term Infection in Cuffed versus Noncuffed Small Bore Central Catheters: A Randomized Trial
Keywords: PICC; peripherally inserted central catheter; SBCC; small-bore central catheter; tPA; tissue-type plasminogen activator;
Phospholipase C is a key enzyme regulating intracellular calcium and modulating the phosphoinositide balance
Keywords: PLC; phospholipase C; PI(4,5)P2; phosphatidylinositol 4,5-bisphosphate; PI(3,4,5)P2; phosphatidylinositol 3,4,5-bisphosphate; Ins(1,4,5)P3; inositol 1,4,5-trisphosphate; DAG; diacylglycerol; PKC; protein kinase C; PI3K; phosphatidylinositol 3-kinase; PDGF
Molecular insights and therapeutic targets for blood–brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator
Keywords: Blood–brain barrier; Neurovascular unit; tPA; MMPs; Ischemic stroke; Signaling pathways
Down-regulation of NF-κB signals is involved in loss of 1α,25-dihydroxyvitamin D3 responsiveness
Keywords: 1,25-VD; 1α,25-dihydroxyvitamin D3; VDR; vitamin D receptor; VDRE; vitamin D response element; PCa; prostate cancer; SRC-1; steroid receptor coactivator-1; DRIP-205; VDR-interacting protein-205; NCoR1; nuclear receptor corepressor 1; SMRT; silencing medi
Fcγ receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection
Keywords: gamma subunit of FcRs; FcγRlll; FcγRllB; parvalbumin neuron; B6; C57BL/6N; COX-2; cyclooxygenase-2; DAB; 2,3,3â²-diaminobenzidine tetrahydrochloride; FcγRs; receptors for Fc portion of immunoglobulin G (IgG); FcRγ; gamma subunit coupled with FcγRl a
Intracellular Calcium Release and Protein Kinase C Activation Stimulate Sonic Hedgehog Gene Expression During Gastric Acid Secretion
Keywords: Somatostatin; Gastrin; Hedgehog Interacting Protein; Chelation; Stomach; BAPTA; 1,2-bis(2-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; Ca2+(i); intracellular calcium; Ctox; H+/K+-β-cholera-toxin-overexpressing; DAG; diacylglycerol; EGTA; ethylen
Studies on glyphosate-induced carcinogenicity in mouse skin: A proteomic approach
Keywords: Glyphosate; TPA; Tumor promotion; Mass spectrometry; Hierarchical cluster analysis; Biomarkers
Consent Issues in Neurology
Keywords: Informed consent; Valid consent, Shared decision making; Emergency exception; tPA; Surrogate; Do-not-resuscitate; Carotid endarterectomy;
Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;
Polymers from renewable 1,4:3,6-dianhydrohexitols (isosorbide, isomannide and isoidide): A review
Keywords: BABC; bisphenol-A bischloroformate; DBTDL; dibutyltin dilaurate; DSC; differential scanning calorimetry; DMAC; dimethylacetamide; DMAP; 4-(dimethylamino)pyridine; DMF; dimethylformamide; DMT; dimethyl terephthalate; LCP; liquid-crystalline polymer; MDI; 4
Commentary: Intraarterial Stroke Revascularization Training Guidelines
Keywords: IA; intraarterial; IV; intravenous; NIHSS; National Institute of Health Stroke Scale; TPA; tissue plasminogen activator;
DNA cleavage promoted by diethylenetriaminepentaacetic acid (DTPA) derivatives
Keywords: TPA; Derivatives; DNA cleavage; Cleavage mechanism;
Outcomes of Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke in Patients Aged 90 Years or Older
Keywords: BI; Barthel Index; ICH; intracerebral hemorrhage; mRS; modified Rankin Scale; NIHSS; National Institutes of Health Stroke Scale; NINDS; National Institute of Neurological Disorders and Stroke; tPA; tissue plasminogen activator;
Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells
Keywords: Silibinin; TPA; MMP-9; COX-2; ERK
Solid-state electrochemiluminescence sensor based on the Nafion/poly(sodium 4-styrene sulfonate) composite film
Keywords: Electrochemiluminescence; Ru(bpy)32+; Nafion/PSS; Ion-exchange; TPA
TRAPDOR double-resonance and high-resolution MAS NMR for structural and template studies in zeolite ZSM-5
Keywords: 14N NMR; 13C NMR; 27Al NMR; TRAPDOR; Double resonance; MQMAS; Zeolite; ZSM-5; MFI; Template; TPA;
Influences of temperature-cycled storage on retrogradation and in vitro digestibility of waxy maize starch gel
Keywords: Waxy maize starch gel; Cycled temperature; Retrogradation; DigestibilityDSC, differential scanning calorimetry; Tg′, glass transition temperature; RDS, rapidly digestible starch; SDS, slowly digestible starch; RS, resistant starch; GI, glycemic index; TPA
Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression
Keywords: Neu2; Sialidases; Rhabdomyosarcoma; p38; Follistatin; bp; base pairs; Cav-3; Caveolin-3; DMEM; Dulbecco's modified Eagle's Medium; FBS; fetal bovine serum; HS; horse serum; MKK6; MAP kinase kinase 6; MyHC; Myosin heavy chain; PBS; phosphate buffered solut
In Vitro Analysis of Downstream Particulates with Mechanical Thrombectomy Devices: Comparison of 20-kHz Sonothrombolytic and Rotating Dispersion Wire Systems
Keywords: RDW; rotating dispersion wire; ST; sonothrombolytic; tPa; tissue-type plasminogen activator;
Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis
Keywords: Stroke; Cytokines; PAI-1; TPA
Synergistic induction of gene expression during the differentiation into mature macrophage in human myeloblastic leukemia cells treated with TPA and KH1060
Keywords: Leukemia; Differentiation; Macrophage; TPA; KH1060; cDNA microarray
Impacto pronóstico del tiempo y el grado de recanalización arterial tras trombólisis con activador tisular del plasminógeno en pacientes con oclusión aguda de la arteria cerebral media
Keywords: tPA; Dúplex transcraneal; Recanalización; Pronóstico; tPA; Transcranial duplex; Recanalization; Prognosis;
Intraarterial Therapy for Acute Ischemic Strokes
Keywords: MERCI; Mechanical Embolus Removal in Cerebral Ischemia; mRS; modified Rankin Scale; NIHSS; National Institutes of Health Stroke Scale; NINDS; National Institute of Neurological Disorders and Stroke; PROACT; Prolyse in Acute Cerebral Thromboembolism; TICI;
Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low-density lipoprotein and accumulation of lipid in differentiated THP-1 cells
Keywords: Apo B; apolipoprotein B-100; LDL; low-density lipoprotein; REM; relative electrophoretic mobility; TBARS; thiobarbituric acid relative substances; TPA; 12-O-tetra-decanoylphorbol-13-acetate; ZLE; leaf extract of Zanthoxylum ailanthoides; Zanthoxylum ailan
Intraventricular thrombolysis for massive intraventricular hemorrhage due to periventricular arteriovenous malformations
Keywords: Intraventricular; Hemorrhage; Thrombolysis; Arteriovenous; Malformation; Brain; Cerebral; rt-PA; tPA;
Locally Applied Recombinant Plasmin Results in Effective Thrombolysis in a Porcine Model of Arteriovenous Graft Thrombosis
Keywords: AV; arteriovenous; TPA; tissue plasminogen activator;
Effect of high pressure processing and cooking treatment on the quality of Atlantic salmon
Keywords: HPP; Fatty acid profile; TBARS; TPA; Colour; Salmon