Keywords: Glucocorticoid; SEGRA; Transrepression; Transactivation; Tetrahydronaphthalene; Amino alcohol;
مقالات ISI (ترجمه نشده)
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Keywords: Myb; p300; Tip60; Transactivation; Protein-protein interaction;
Keywords: GHRH; Triple-negative breast cancer; EGFR; Transactivation; Cell migration; GHRH antagonist;
Keywords: Alligator; AHR; ARNT; Transactivation;
Keywords: Glucocorticoid; Corticosteroid; Transactivation; Transrepression; Inflammation; Anti-inflammatory
Keywords: Amax; maximal transactivation; bHLH; basic helix-loop-helix motif; BMAL1; brain and muscle arnt-like 1; CLOCK; circadian locomoter output cycle kaput; CRY1; cryptochrome 1; DEX; dexamethasone; EC50; efficacy or half-effective concentration; FKBP5; FK506 b
G protein coupled receptors can transduce signals through carboxy terminal and linker region phosphorylation of Smad transcription factors
Keywords: Transactivation; Smads; TGF-β; G protein coupled receptor; Phosphorylation;
Etanercept restores vasocontractile sensitivity affected by mesenteric ischemia reperfusion
Keywords: Etanercept; Tumor necrosis factor-α receptor; Mesenteric ischemic reperfusion injury; Transactivation;
ZFP36L2, a novel AML1 target gene, induces AML cells apoptosis and inhibits cell proliferation
Keywords: AML1; AML1-ETO; ZFP36L2; Transactivation; Cell cycle; Apoptosis;
Synthesis of 2α- and 2β-(3-hydroxypropyl)- 7,8-cis-14-epi-1α,25-dihydroxy-19-norvitamin D3 and their biological activity
Keywords: Synthesis; 7,8-cis-19-norvitamin D3 analog; Vitamin D receptor; VDR binding affinity; Transactivation;
Research articleSumoylation regulates the transcriptional activity of different human NFAT isoforms in neurons
Keywords: NFAT Ca2+-regulated transcription factor; Neuronal activity; Sumoylation; Transactivation; Neurons;
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation
Keywords: Selective glucocorticoid receptor modulator (SGRM); Transrepression; Transactivation; Non-steroidal; JTP-117968;
Characterization of a thienylcarboxamide derivative that inhibits the transactivation functions of cytomegalovirus IE2 and varicella zoster virus IE62
Keywords: Cytomegalovirus; Varicella zoster virus; Antiviral; Compound; Transactivation; Immediate-early gene; Host factor;
Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells
Keywords: Endothelin; Lung cancer; Transactivation; EGFR; HER2;
Existence of muscarinic acetylcholine receptor (mAChR) and fibroblast growth factor receptor (FGFR) heteroreceptor complexes and their enhancement of neurite outgrowth in neural hippocampal cultures
Keywords: FGFR1; M1 receptor; Transactivation; Heteroreceptor complexes; Neural plasticity;
Research articleMolecular cloning and characterization of hagfish estrogen receptors
Keywords: Agnathan; Eptatretus burgeri; Estrogen receptor; Molecular cloning; Transactivation;
Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection
Keywords: ATPase; HIV-1; Protein secretion; Surface plasmon resonance; Tat; Transactivation;
SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via vitamin D receptor deacetylation
Keywords: VDR; Vitamin D; Sirtuin-1; Resveratrol; Acetylation; Transactivation;
Research articleNuclear localization and transactivation by Vitis CBF transcription factors are regulated by combinations of conserved amino acid domains
Keywords: CBF pathway; Vitis species; Nuclear localization signal; Transactivation;
Comparative analysis of ginsenosides in human glucocorticoid receptor binding, transactivation, and transrepression
Keywords: Ginsenoside Rb1 (PubChem CID: 9898279); Ginsenoside Rb2 (PubChem CID: 6917976); Ginsenoside Rc (PubChem CID: 12855889); Ginsenoside Rd (PubChem CID: 11679800); Ginsenoside Rh2 (PubChem CID: 119307); Ginsenoside Compound K (PubChem CID: 9852086); 20(S)-Pro
Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection
Keywords: EGFR; ErbB; Cardioprotection; G protein-coupled receptors; Ischaemia-reperfusion; Preconditioning; Transactivation;
Direct coupling of the HER4 intracellular domain (4ICD) and STAT5A signaling is required to induce mammary epithelial cell differentiation
Keywords: 4ICD; HER4 intracellular domain; ATCC; American type culture collection; EGF; epidermal growth factor; EGFP; enhanced green fluorescent protein; EGFR; epidermal growth factor family; ERα; estrogen receptor alpha; FBS; fetal bovine serum; HEK; human embry
Synthesis, metabolism, and biological activity of 2-[3-(tetrazolyl)propyl]-1α,25-dihydroxy-19-norvitamin D3
Keywords: Synthesis; Metabolism; 19-Norvitamin D3 analog; Vitamin D receptor; CYP24A1; Transactivation;
Cross-talk between lysophosphatidic acid receptor 1 and tropomyosin receptor kinase A promotes lung epithelial cell migration
Keywords: LPA; GPCR; RTK; Transactivation; Receptor internalization; Cell migration;
“Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes”
Keywords: CD1d; αGC; NKT cells; Glycolipid; Antigen presentation; NK activation; transactivation; IFNγ secretion; Dendritic cells; Endosomal presentation; Endosomal pH; pH neutralization;
Towards the emerging crosstalk: ERBB family and steroid hormones
Keywords: Steroid hormones; Receptor tyrosine kinase; Regulatory crosstalk; Feedback regulation; Cancer therapy; Tethering; Transrepression; Transactivation; Chronotherapy; EGFR; Glucocorticoid receptor; Negative feedback; Positive feedback;
Estrogenic activity of isoflavonoids from the stem bark of the tropical tree Amphimas pterocarpoides, a source of traditional medicines
Keywords: AlkP; alkaline phosphatase; BW; body weight; ERα; estrogen receptor α; ERβ; estrogen receptor β; ERE; estrogen response element; E2; estradiol; EGF; epidermal growth factor; HPLC-DAD; high pressure liquide chromatography with diode-array detection; HR
Anti-cancer effect of (-)-epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of β-catenin
Keywords: β-catenin; (-)-epigallocatechin-3 gallate; Head and cancer; Transactivation; Ubiquitination; P53; HNC; Head and neck cancer; EGCG; (-)-Epigallocatechin-3-gallate; TCF; T cell/lymphoid enhancer factor; DMEM; Dulbecco's modified Eagle's medium; MEM; Minimu
Research paperERK activated by Histamine H1 receptor is anti-proliferative through spatial restriction in the cytosol
Keywords: GPCRs; Transactivation; ERK; H1 receptor; Live cell imaging; FRAP;
New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile
Keywords: PPARγ; Transactivation; Cytotoxicity; Binding mode; Molecular modeling; Amax; maximum intrinsic activity; BPO; benzoyl peroxide; DMEM; Dulbecco's modified Eagle medium; LBD; ligand binding domaine; mp; melting point; NBS; N-bromosuccinimide; PPAR; peroxi
Substance-specific importance of EGFR for vascular smooth muscle cells motility in primary culture
Keywords: Epidermal growth factor receptor; Vascular smooth muscle cells; Migration; Proliferation; Gene expression; Transactivation;
Synthesis and biological activities of vitamin D3 derivatives with cyanoalkyl side chain at C-2 position
Keywords: Vitamin D3; 2α-Functionalized vitamin D; Vitamin D receptor; Binding affinity; Transactivation; X-ray co-crystallographic analysis;
Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes
Keywords: CD1d; αGC; NKT cells; Glycolipid; Antigen presentation; NK activation; transactivation; IFNγ secretion; Dendritic cells; Endosomal presentation; Endosomal pH; pH neutralization
E2F1 promote the aggressiveness of human colorectal cancer by activating the ribonucleotide reductase small subunit M2
Keywords: Ribonucleotide reductase small subunit M2; E2F1; Colorectal cancer; Transactivation;
Hepassocin activates the EGFR/ERK cascade and induces proliferation of L02 cells through the Src-dependent pathway
Keywords: HPS; EGFR; Transactivation; ERK; Src;
Activation of farnesoid X receptor induces RECK expression in mouse liver
Keywords: FXR; farnesoid X receptor; RXRα; retinoid X receptor α; SHP; small heterodimer partner; SREBP-1c; sterol regulatory element-binding protein-1c; PEPCK; phosphoenolpyruvate carboxykinase; RECK; reversion-inducing cysteine rich protein with Kazal motifs; M
Residues R199H200 of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization
Keywords: Bel1; Nuclear localization signal (NLS); Long terminal repeat (LTR); Internal promoter (IP); Transactivation;
Histone methyltransferase SMYD3 promotes MRTF-A-mediated transactivation of MYL9 and migration of MCF-7 breast cancer cells
Keywords: Breast cancer; MRTF-A; SMYD3; Cell migration; Transactivation; Histone methylation; MYL9
The upstream stimulatory factor USF1 is regulated by protein kinase CK2 phosphorylation
Keywords: Protein kinase CK2; Phosphorylation; Hetero-dimerization; Transcription factor; Transactivation;
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands
Keywords: DMLs; 6-Desfluoroquinolones; RT; Transactivation; Anti-HIV compounds
Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve
Keywords: Folliculogenesis; ovarian reserve; transactivation;
SR48692 inhibits non-small cell lung cancer proliferation in an EGF receptor-dependent manner
Keywords: Neurotensin; Epidermal growth factor receptor; Transactivation; Lung cancer; siRNA
Defining the roles of the baculovirus regulatory proteins IE0 and IE1 in genome replication and early gene transactivation
Keywords: Baculovirus; AcMNPV; IE0; IE1; DNA replication; Transactivation; Gene expression; Transcription factor;
Heterocyclic glucocorticoid receptor modulators with a 2,2-dimethyl-3-phenyl-N-(thiazol or thiadiazol-2-yl)propanamide core
Keywords: Glucocorticoid receptor; Non-steroidal glucocorticoid receptor agonists; Dissociated steroids; Transrepression; Transactivation;
Synthesis of novel C-2 substituted vitamin D derivatives having ringed side chains and their biological evaluation on bone
Keywords: Vitamin D3; Vitamin D receptor; Vitamin D analogs; Transactivation; Human osteosarcoma cell; Ovariectomized (OVX) rat model;
WKYMVm-induced cross-talk between FPR2 and HGF receptor in human prostate epithelial cell line PNT1A
Keywords: FPR2; c-Met; NADPH oxidase; Transactivation; Signal transduction;
In brown adipocytes, adrenergically induced β1-/β3-(Gs)-, α2-(Gi)- and α1-(Gq)-signalling to Erk1/2 activation is not mediated via EGF receptor transactivation
Keywords: Transactivation; G-protein-coupled receptors; Erk1/2 activation; Brown adipocytes; Norepinephrine;
5-HT1A receptors transactivate the platelet-derived growth factor receptor type beta in neuronal cells
Keywords: 5-HT; 5-hydroxytryptamine, serotonin; 5-CT; 5-carboxamidotryptamine; PDGF; platelet-derived growth factor; PLC; phospholipase C; Ptx; pertussis toxin; GPCR; G protein-coupled receptor; ERK; extracellular signal-regulated kinase; EGTA; ethylene glycol tetr
Mécanismes d’action des glucocorticoïdes
Keywords: Glucocorticoïdes; Récepteur; Transactivation; Transrépression; InflammationGlucocorticoids; Glucocorticoid receptor; Transactivation; Transrepression; Inflammation
Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation
Keywords: Respiratory syncytial virus; Glucocorticoid receptor; Transactivation; Phosphorylation; Protein phosphatase