Keywords: مدل موش ترانسژنیک; Dendritic spines; 14-3-3 Proteins; Neurotransmission; Prefrontal cortex; Schizophrenia; Transgenic mouse model
مقالات ISI مدل موش ترانسژنیک (ترجمه نشده)
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Keywords: مدل موش ترانسژنیک; Hypertension; Aldosterone; Angiotensin; Diuretics; Transgenic mouse model;
Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Cerebral amyloidosis; Neocortex; Monoamine; Serotonin; Selective serotonin reuptake inhibitor; SERT occupancy; [3H]DASB; Autoradiography; Transgenic mouse model; 5,7-dihydroxytryptamine; Stereology;
Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model
Keywords: مدل موش ترانسژنیک; Type III collagen; Vascular Ehlers-Danlos syndrome; Heritable connective tissue disorder; Transgenic mouse model; Fibrillogenesis;
Characterization of an 'Amyloid Only' Transgenic (B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax) Mouse Model of Alzheimer's Disease
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; amyloid; immunohistochemistry; transgenic mouse model;
Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease
Keywords: مدل موش ترانسژنیک; 5-HT4 receptor agonist; Alzheimer's disease; Memory impairments; Olfactory tubing maze; Transgenic mouse model; Pharmacotherapy; 5-HT4R; 5-Hydroxytryptamine type 4 receptor; Aβ; Amyloid beta peptide; AD; Alzheimer's Disease; ApoE; Apolipoprotein E; APP;
Research articleDisinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia
Keywords: مدل موش ترانسژنیک; Frontotemporal dementia; Tau; Transgenic mouse model; Behavior;
Research paperGradual development of psoriatic skin lesions by constitutive low-level expression of IL-17A
Keywords: مدل موش ترانسژنیک; AMP; antimicrobial peptides; BM; bone-marrow; DC; dendritic cells; KC; keratinocytes; LC; Langerhans cells; LDC; Langerin+ DC; Tg; transgenic; TLR; toll-like receptor; Epidermal barrier; Interleukin-17; Psoriasis; Skin inflammation; Transgenic mouse model
Development of transgenic mouse model expressing porcine aminopeptidase N and its susceptibility to porcine epidemic diarrhea virus
Keywords: مدل موش ترانسژنیک; Porcine coronaviruses; Porcine APN; Pathogenesis; Porcine epidemic diarrhea virus; Transgenic mouse model
T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice
Keywords: مدل موش ترانسژنیک; Lupus; T cells; PKCδ; Transgenic mouse model; Extracellular signal-regulated kinase (ERK); Autoimmunity;
Research reportHesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Hesperidin; Transgenic mouse model; Cerebral amyloidosis; Behavioral deficit; Neuro-inflammation;
The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Microglia; Adeno-associated virus; Neuroinflammation; Transgenic mouse model; CD200;
Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Transgenic mouse model; Radial maze; Hippocampal slice; Amyloid-beta; Synaptic plasticity;
Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Transgenic mouse model; Amyloid beta; Tau protein; Behavior; Synapse; Sleep deprivation;
Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14
Keywords: مدل موش ترانسژنیک; Spinocerebellar ataxia type 14; Protein kinase C gamma; Purkinje cell dendritic development; Transgenic mouse model;
Mice with cardiac-restricted overexpression of Myozap are sensitized to biomechanical stress and develop a protein-aggregate-associated cardiomyopathy
Keywords: مدل موش ترانسژنیک; Intercalated disc; Cardiomyopathy; Transgenic mouse model; SRF; Protein aggregates;
Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain
Keywords: مدل موش ترانسژنیک; 5xFAD; Five familial Alzheimer's disease mutations; Aβ; β-Amyloid; AD; Alzheimer's disease; FOV; Field of view; H; Hippocampus; LC; Lower cortex; MBP; Myelin basic protein; MRI; Magnetic resonance imaging; NeuN; Neuron-specific nuclear protein; ROI; Reg
The Influence of 5-Lipoxygenase on Alzheimer’s Disease-Related Tau Pathology: In Vivo and In Vitro Evidence
Keywords: مدل موش ترانسژنیک; 5-Lipoxygenase; Alzheimer’s disease; amyloid beta; cyclin dependent kinase-5; tau protein; transgenic mouse model
Mouse liver-specific CD8+ T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes
Keywords: مدل موش ترانسژنیک; Autoimmune hepatitis; Transgenic mouse model; Autoreactive CD8+ T-cells; Peripheral tolerance mechanisms
Transgenic models of Alzheimer's disease: Better utilization of existing models through viral transgenesis
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Neurodegeneration; Transgenic mouse model; Adeno-associated virus; Lentivirus
Correlation of Aβ deposition in the nasal cavity with the formation of senile plaques in the brain of a transgenic mouse model of Alzheimer's disease
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Nasal cavity; Beta amyloid peptide; Transgenic mouse model; Senile plaques
Cognitive phenotyping of amyloid precursor protein transgenic J20 mice
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Transgenic mouse model; J20; APP; Learning and memory
The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model
Keywords: مدل موش ترانسژنیک; Friedreich ataxia; FRDA, frataxin; GAA trinucleotide repeat; Transgenic mouse model; Mismatch repair; MMR; Msh2; Msh3; Msh6; Pms2
Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy
Keywords: مدل موش ترانسژنیک; Oculopharyngeal muscular dystrophy; Transgenic mouse model; PABPN1; Myopathy; Cardiomyopathy; Protein aggregation; Nuclear inclusion;
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
Keywords: مدل موش ترانسژنیک; Huntington disease; Transgenic mouse model; Lithium; Caspase-6; BDNF; GSK-3; Tau;
Anxiety phenotype in mice that overexpress protein kinase A
Keywords: مدل موش ترانسژنیک; Protein kinase A; Transgenic mouse model; Anxiety; Behavioral phenotype; Amygdala;
Correlation among nuclear localization of NuMA-RARα, deregulation of gene expression and leukemic phenotype of hCG-NuMA-RARα transgenic mice
Keywords: مدل موش ترانسژنیک; NuMA-RARα; Acute promyelocytic leukemia; Transgenic mouse model; Transgene dosage; Transcriptional repression; Nuclear localization;
The accessible cerebral vascular proteome in a mouse model of cerebral β-amyloidosis
Keywords: مدل موش ترانسژنیک; Aβ; Alzheimer disease; Amyloid; Cerebral vascular proteome; Transgenic mouse model; Comparative proteomics; Label-free protein quantification
Alzheimer-associated mutant ubiquitin impairs spatial reference memory
Keywords: مدل موش ترانسژنیک; Ubiquitin-proteasome system; Neurodegeneration; Transgenic mouse model; Mutant ubiquitin; Behavior;
Rapid Cerebral Amyloid Binding by Aβ Antibodies Infused into β-Amyloid Precursor Protein Transgenic Mice
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; amyloid; dementia; immunotherapy; neuropsychiatry; transgenic mouse model
Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs
Keywords: مدل موش ترانسژنیک; Dinucleotide; Prodrugs; Anti-HBV activity; Antiviral activity; Transgenic mouse model; ADME studies; Oral bioavailability
The use of mouse models to better understand mechanisms of autoimmunity and tolerance
Keywords: مدل موش ترانسژنیک; Autoimmunity; CD8 T cells; GvHD; Immunological tolerance; Transgenic mouse model
New roles for insulin-like hormones in neuronal signalling and protection: New hopes for novel treatments of Alzheimer’s disease?
Keywords: مدل موش ترانسژنیک; Alzheimer; LTP; Transgenic mouse model; Insulin; Synaptic plasticity; Synaptic transmission; Hippocampus; Growth factor
Vascular response to acetazolamide decreases as a function of age in the arcAβ mouse model of cerebral amyloidosis
Keywords: مدل موش ترانسژنیک; Acetazolamide; Alzheimer's disease (AD); Cerebral amyloid angiopathy (CAA); Cerebral blood volume (CBV); Functional magnetic resonance imaging (fMRI); Transgenic mouse model
Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo
Keywords: مدل موش ترانسژنیک; Cardiomyocyte; Hypertrophy; Calcineurin; Transgenic mouse model; Adenovirus
A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats
Keywords: مدل موش ترانسژنیک; Spinocerebellar ataxia type 3; Machado–Joseph disease; SCA3; MJD; Polyglutamine; Intranuclear inclusion bodies; Transgenic mouse model; CAG repeat instability; Late onset
Context-dependent perturbation of neural systems in transgenic mice expressing a cytosolic prion protein
Keywords: مدل موش ترانسژنیک; Prion protein (PrP); Magnetic resonance imaging (MRI); Manganese; Neural activity mapping; Neurodegenerative disease; Transgenic mouse model;
Generation and characterization of JSRV envelope transgenic mice in FVB background
Keywords: مدل موش ترانسژنیک; Jaagsiekte sheep retrovirus; Envelope protein; Lung cancer; Transgenic mouse model
Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease
Keywords: مدل موش ترانسژنیک; Huntington's disease; N171-82Q; Neurturin; CERE-120; Gene therapy; Transgenic mouse model; AAV2
Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; Cerebral amyloid angiopathy; Transgenic mouse model; Magnetic resonance angiography; Cerebral blood flow
Mamu-A⁎01/Kb transgenic and MHC Class I knockout mice as a tool for HIV vaccine development
Keywords: مدل موش ترانسژنیک; Mamu A⁎01; SIV; Transgenic mouse model; Cellular immunity; Peptide vaccine; Poxvirus challenge
Creatine uptake in mouse hearts with genetically altered creatine levels
Keywords: مدل موش ترانسژنیک; Creatine transport; Creatine; Energy metabolism; GAMT; Transgenic mouse model;
Elucidation of the role of COX-2 in liver fibrogenesis using transgenic mice
Keywords: مدل موش ترانسژنیک; COX-2; Liver fibrosis; Transgenic mouse model; Fibrotic factors
Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1
Keywords: مدل موش ترانسژنیک; HSV-1; apolipoprotein E; brain; cornea; herpetic stromal keratitis; trigeminal ganglia; transgenic mouse model; vascular endothelial growth factor;
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease
Keywords: مدل موش ترانسژنیک; Huntington's disease; Tiagabine; Neuroprotection; Transgenic mouse model; Preclinical trials
A fusion protein of HCMV IE1 exon4 and IE2 exon5 stimulates potent cellular immunity in an MVA vaccine vector
Keywords: مدل موش ترانسژنیک; Human cytomegalovirus; Viral vaccine; Attenuated poxvirus; Cellular immunity; Transgenic mouse model; Memory T cells; Regulatory proteins; Tegument protein
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S
Keywords: مدل موش ترانسژنیک; Transgenic mouse model; Long QT syndrome (LQTS); LQT3; Ventricular arrhythmia; Sudden death; Cardiac sodium channel gene SCN5A; Mutation; Optical mapping; Reentry arrhythmia; Increased automaticity
Targeted inactivation of the murine Abca3 gene leads to respiratory failure in newborns with defective lamellar bodies
Keywords: مدل موش ترانسژنیک; ABCA3; Transgenic mouse model; Lamellar body; Respiratory distress syndrome; Surfactant; Newborn; Atelectasis
Mood and male sexual behaviour in the APP23 model of Alzheimer's disease
Keywords: مدل موش ترانسژنیک; Alzheimer's disease; APP23 model; Transgenic mouse model; Depressive behaviour; Anxiety; Sexual behaviour
A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia
Keywords: مدل موش ترانسژنیک; Glycogen cardiomyopathy; AMPK; Transgenic mouse model; Cardiac hypertrophy; Myocardial ischemia–reperfusion