Keywords: انسداد شریان مغزی میانی متناوب; AChA; anterior choroidal artery; AChAO; anterior choroidal artery occlusion; ET-1; endothelin-1; MCA; middle cerebral artery; MCAO; middle cerebral artery occlusion; pMCAO; permanent middle cerebral artery occlusion; tMCAO; transient middle cerebral arter
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Keywords: انسداد شریان مغزی میانی متناوب; CVD; cardiovascular diseases; ROS; reactive oxygen species; MI; myocardial infarction; ECM; extracellular matrix; HIF; hypoxia-inducible factor; VEGF; vascular endothelial growth factor; NF-кB; nuclear factor-кB; DOX; doxorubicin; MDA; malondialdehyde;
Keywords: انسداد شریان مغزی میانی متناوب; Early inflammatory infiltrate; Digital morphometry; M1/M2 macrophages; COX-2; FXIII; Cerebral ischemia; MMPs; matrix metalloproteinases; PMNs; polymorphonuclear neutrophils; tMCAO; transient middle cerebral artery occlusion; S; sham group; I; ischemic gro
Keywords: انسداد شریان مغزی میانی متناوب; 2OAA; 2-hydroxyarachidonic acid; 4-HNE; 4-hydroxynonenal; AA; arachidonic acid; C-Pu; caudate-putamen; CCA; common carotid artery; cPLA2; cytosolic phospholipase A2; COX; cyclooxygenase; DHA; docosahexaenoic acid; ECA; external carotid artery; FFA; free f
Keywords: انسداد شریان مغزی میانی متناوب; Seipin; Knockout mice; Lipodystrophy; Ischemic stroke; Transient middle cerebral artery occlusion;
Keywords: انسداد شریان مغزی میانی متناوب; CNS; central nervous system; CHIP; C terminus of heat shock cognate protein 70 (Hsc70)-interacting protein; E2; 17β-estradiol; ER; estrogen receptor; GCI; global cerebral ischemia; HRT; hormone replacement therapy; LTED; long-term 17β-estradiol deprivat
Keywords: انسداد شریان مغزی میانی متناوب; Angiotensin 2 type 1 receptor; ischemic stroke; metabolic syndrome; peroxisome proliferator-activated receptor gamma; spontaneously hypertensive rat; transient middle cerebral artery occlusion;
Keywords: انسداد شریان مغزی میانی متناوب; CREB; cAMP-response element-binding protein; I/R; HCO-60, polyoxyethylene (60) hydrogenated castor oil; MPO; myeloperoxidase; I/R; ischemia-reperfusion; t-MCAO; transient middle cerebral artery occlusion; TG; TokyoGreen; TTC; 2,3,5-triphenyltetrazolium
Keywords: انسداد شریان مغزی میانی متناوب; IL-1Ra; interleukin-1 receptor antagonist; MRI; magnetic resonance imaging; MBP; myelin basic protein; SR; skilled reaching; SW; skilled walking; tMCAo; transient middle cerebral artery occlusion; Behavior; Cerebral ischemia; Skilled reaching; Fine motor
Keywords: انسداد شریان مغزی میانی متناوب; I/R; ischemia/reperfusion; p-MCAO; permanent middle cerebral artery occlusion; t-MCAO; transient middle cerebral artery occlusion; Ischemic stroke; Liposome; Ischemic penumbra; Middle cerebral artery occlusion; Laser Doppler perfusion imaging;
Keywords: انسداد شریان مغزی میانی متناوب; AD; Alzheimer's disease; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; BSA; bovine serum albumin; CaMK; Ca2+/calmodulin-dependent protein kinases; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; ER;
Keywords: انسداد شریان مغزی میانی متناوب; ECM; extracellular matrix; NF-κB; nuclear factor kappa B; Akt; protein kinase B; tPA; tissue plasminogen activator; TSRs; thrombospondin type 1 repeats; PDGF; platelet-derived growth factor; PCR; polymerase chain reaction; MCA; middle cerebral artery; CB
A-Kinase-Anchoring Protein (AKAP150) is expressed in Astrocytes and Upregulated in Response to Ischemia
Keywords: انسداد شریان مغزی میانی متناوب; AKAP; A-Kinase-Anchoring Protein; BBSS; bicarbonate-buffered balanced salt solution; tMCAO; transient middle cerebral artery occlusion; potassium uptake; membrane potential; middle cerebral artery occlusion; siRNA; cortical astrocytes;
Antineuroinflammatory Effect of SMTP-7 in Ischemic Mice
Keywords: انسداد شریان مغزی میانی متناوب; Apoptosis-Inflammation-Ischemic stroke-tPA-SMTP-7; BSA; bovine serum albumin; CBF; cerebral blood flow; CCA; common carotid artery; d; days; DAB; 3,3â²-diaminobenzidine; ECA; external carotid artery; ECL; enhanced chemiluminescent; EET; epoxyeico
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia
Keywords: انسداد شریان مغزی میانی متناوب; Na+/Ca2+ exchanger; Neonatal hypoxia; Learning and memory; Motor behaviour; Adenosin-triphosphat; (ATP); 7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1Hbenzo[e][1,4]diazepin-2(3H)-one; (neurounina); Cornu Ammonis; (CA); Glial Fibrillary Acidic protein; (GFA
Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage
Keywords: انسداد شریان مغزی میانی متناوب; ADC; apparent diffusion coefficient; ATf; apotransferrin; B-27; a medium supplement to grow neurons; BBB; blood-brain barrier; CM; conditioned medium; CM-H2DCFDA; 5-chloromethyl-2,7-dichlorodihydrofluorescein diacetate; DAPK-1; anti-death-associated prote
Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons
Keywords: انسداد شریان مغزی میانی متناوب; Actb; β-actin; Aβ; amyloid beta; AD; Alzheimer's disease; ANOVA; analysis of variance; ASD; autism spectrum disorder; BP-3; benzophenone-3; BPA; bisphenol A; BPs; benzophenones; BSA; bovine serum albumin; Casp3; caspase-3; CNS; central nervous system; D
Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
Keywords: انسداد شریان مغزی میانی متناوب; AMPK; AMP-activated protein kinase; CaMKKβ; calcium/calmodulin-dependent protein kinase kinase beta; CBF; cerebral blood flow; CCA; common carotid artery; EBSS; glucose-free Earle's balanced salt solution; ECA; external carotid artery; ELISA; cytokine en
Neuroprotective efficacy of poly-arginine R18 and NA-1 (TAT-NR2B9c) peptides following transient middle cerebral artery occlusion in the rat
Keywords: انسداد شریان مغزی میانی متناوب; Transient middle cerebral artery occlusion; Neuroprotection; Stroke; R18; NA-1 (TAT-NR2B9c); Poly-arginine peptides;
ALA16VAL-MnSOD gene polymorphism and stroke: Association with dyslipidemia and glucose levels
Keywords: انسداد شریان مغزی میانی متناوب; AA; alanine/alanine; Ala; alanine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AV; alanine/valine; CAT; catalase; CHO; cholesterol; dsDNA; double strand DNA; DMStroke; diabetic mellitus Stroke; dStroke; dislipidemic stroke; eNOS; endot
Neuroprotective DAMPs member prothymosin alpha has additional beneficial actions against cerebral ischemia-induced vascular damages
Keywords: انسداد شریان مغزی میانی متناوب; Cerebral ischemia; Prothymosin alpha; Vascular and neuronal protection; CBB; Coomassie Brilliant Blue; IgG; immunoglobulin G; i.p.; intraperitoneal; i.v.; intravenous; ProTα; prothymosin alpha; TEV; tobacco etch virus; tMCAO; transient middle cerebral ar
Protective effect of Naoxintong against cerebral ischemia reperfusion injury in mice
Keywords: انسداد شریان مغزی میانی متناوب; NXT; Naoxintong; tMCAO; Transient Middle Cerebral Artery Occlusion; IHC; Immunohistochemistry; qRT-PCR; Quantitative Reverse Transcription-Polymerase Chain Reaction; LOX-1; Lectin-like Oxidized Low-Density Lipoprotein Receptor-1; ERK; Extracellular Regula
4â²-O-β-D-Glucosyl-5-O-Methylvisamminol, A Natural Histone H3 Phosphorylation Epigenetic Suppressor, Exerts a Neuroprotective Effect Through PI3K/Akt Signaling Pathway on Focal Cerebral Ischemia in Rats
Keywords: انسداد شریان مغزی میانی متناوب; 4â²-O-β-D-glucosyl-5-O-methylvisamminol; Phosphatidylinositol-3-kinase; Protein kinase B; Transient middle cerebral artery occlusion; Tumor necrotic factor-α; Bad; Bcl-2-associated death promoter; BrdU; 5-Bromo-2â²-deoxyuridine; BWI; Brain water ind
Regular ArticleFullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats
Keywords: انسداد شریان مغزی میانی متناوب; OH-F; fullerenol; GlcN; glucosamine; GlcN-F; glucosamine fullerene; WKY; Wistar-Kyoto-rats; SHR; spontaneously hypertensive rats; tMCAO; transient middle cerebral artery occlusion; TLR-4; toll-like receptor 4; IL-1 β; interleukin 1 β; TNF-α; tumor necr
CXCR4+CD45â BMMNC subpopulation is superior to unfractionated BMMNCs for protection after ischemic stroke in mice
Keywords: انسداد شریان مغزی میانی متناوب; BMMNC; bone marrow mononuclear cell; tMCAO; transient middle cerebral artery occlusion; FACS; fluorescence-activated cell sorting; HSC; hematopoietic stem cell; EPC; endothelial progenitor cell; MSC; mesenchymal stem cell; TCSC; tissue-committed stem cell
KB-R7943, an inhibitor of the reverse Na+/Ca2+ exchanger, does not modify secondary pathology in the thalamus following focal cerebral stroke in rats
Keywords: انسداد شریان مغزی میانی متناوب; Amyloid precursor protein; β-Amyloid; Calcium; KB-R7943; Sodium/calcium exchanger; Transient middle cerebral artery occlusion;
The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins
Keywords: انسداد شریان مغزی میانی متناوب; ANGPT-1; angiopoietin 1; CCA; common carotid arteries; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; GFAP; glial fibrillary acidic protein; HMGIY/HMGA1; high-mobility group I-Y protein; MTT; 3-(4,5-dimethylthiazol)-2,5-diphen
The protective role of Tongxinluo on blood-brain barrier after ischemia-reperfusion brain injury
Keywords: انسداد شریان مغزی میانی متناوب; BBB; blood-brain barrier; CBF; cerebral blood flow; EB; Evans blue; MCA; middle cerebral artery; MPO; myeloperoxidase; tMCAO; transient middle cerebral artery occlusion; TXL; tongxinluo; TJ; tight junction; ZO-1; Zonula occludens-1; Brain edema; Inflamm
A single injection of liposomal asialo-erythropoietin improves motor function deficit caused by cerebral ischemia/reperfusion
Keywords: انسداد شریان مغزی میانی متناوب; AEPO; Asialo-erythropoietin; AEPO-liposomes; AEPO-modified PEGylated liposomes; I/R; ischemia/reperfusion; NeuN; neuronal nuclei; t-MCAO; transient middle cerebral artery occlusion; Ischemic stroke; Middle cerebral artery occlusion; Asialo-erythropoietin;
Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice
Keywords: انسداد شریان مغزی میانی متناوب; AP-1; activator protein 1; ATF3; Activating transcription factor; CBF; cerebral blood flow; CREB; cAMP-responsive element-binding protein; HDAC1; histone deacetylase 1; ICAM; intercellular adhesion molecule; IL; interleukin; KO; knockout; MCA; middle cere
Research ReportImprovement of deficits by transplantation of lentiviral vector-modified human amniotic mesenchymal cells after cerebral ischemia in rats
Keywords: انسداد شریان مغزی میانی متناوب; hAMCs; Human amniotic mesenchymal cells; BDNF; brain derived neurotrophic factor; iPS; induced pluripotent stem; MCAO; transient middle cerebral artery occlusion; HAM; human amniotic membrane; ECA; external carotid artery; ICA; internal carotid artery; TT
Short-term low intensity PMF does not improve functional or histological outcomes in a rat model of transient focal cerebral ischemia
Keywords: انسداد شریان مغزی میانی متناوب; Spontaneously Hypertensive rat; Transcranial magnetic stimulation; Transient focal cerebral ischemia; Transient middle cerebral artery occlusion
Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2
Keywords: انسداد شریان مغزی میانی متناوب; BB; bilobalide; CRMP2; collapsin response mediator protein 2; EGb 761; Ginkgo biloba/EGb 761®; GA; ginkgolide A; GB; ginkgolide B; HO1; heme oxygenase 1; H2O2; hydrogen peroxide; MCA; middle cerebral artery; NDS; neurologic deficit score; NMDA; N-Methyl-
Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia
Keywords: انسداد شریان مغزی میانی متناوب; IPC; ischemic preconditioning; MCA; middle cerebral artery; tMCAO; transient middle cerebral artery occlusion; pMCAO; permanent distal middle cerebral artery occlusion; HO1; heme oxygenase 1; TIA; transient ischemic attack; WT; wildtype; HO1â/â mice;
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia
Keywords: انسداد شریان مغزی میانی متناوب; cerebral ischemia; middle cerebral artery occlusion; mouse; prostaglandins; PGD2; CBF; cerebral blood flow; COX; cyclooxygenase; H-PGDS; hematopoietic prostaglandin D synthase; L-PGDS; lipocalin-type prostaglandin D synthases; MABP; mean arterial blood pr
Neutrophil elastase and neurovascular injury following focal stroke and reperfusion
Keywords: انسداد شریان مغزی میانی متناوب; Protease; Blood–brain barrier; Ischemia; Transient middle cerebral artery occlusion; Vasogenic edema; Leukocyte–endothelial adherence
The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice
Keywords: انسداد شریان مغزی میانی متناوب; Cerebral ischemia; Transient middle cerebral artery occlusion; Two-pore domain potassium channels; TASK channels; Thalamic neurons; TASK1−/− mice; Electrophysiology
Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats
Keywords: انسداد شریان مغزی میانی متناوب; Transient middle cerebral artery occlusion; Subcortical infarction; Behavior test; Methamphetamine; Montoya staircase test
Relevance of astrocytic activation to reductions of astrocytic GABAA receptors
Keywords: انسداد شریان مغزی میانی متناوب; CNS; central nervous system; DIV; days in vitro; DMEM; Dulbecco's modified Eagle's medium; EGABA; reversal potential for GABA; ECl; reverse potential for Clâ; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; GABA; γ-aminobutyric acid; GABAA; γ
Expression of neurocan after transient middle cerebral artery occlusion in adult rat brain
Keywords: انسداد شریان مغزی میانی متناوب; Disorders of the nervous system; Ischemia; ACA; anterior cerebral artery; CBF; cerebral blood flow; CNS; central nervous system; CSPGs; chondroitin sulfate proteoglycans; DAPI; 4â²,6â²-diamidino-2-phenylindole; ECM; extracellular matrix; FITC; fluoresce