Keywords: مارپیچ فرابنفش; Alzheimer's Disease; Beta-secretase; BACE1; Transmembrane helix; Transmembrane domain; Helix packing; Trimer; Copper; Metal ion; Sulfur; Methionine; Cysteine; Channels and transporters; Molecular dynamics; MD simulations;
مقالات ISI مارپیچ فرابنفش (ترجمه نشده)
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Keywords: مارپیچ فرابنفش; GWALP23; acetyl-GGALWLALALALALALALWLAGA-amide; DLPC; 1,2-dilauroyl-sn-glycero-3-phosphocholine; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocholine; pHLIP; pH driven low insertion peptides; POPC; 1-palmitoyl-2
Keywords: مارپیچ فرابنفش; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CHO; Chinese hamster ovary; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GLP-1; glucagon-like peptide-1; GPCR; G protein-coupled receptor; iCa2+; intracellular calcium; pERK; extracellu
Keywords: مارپیچ فرابنفش; Activity-based probes; Inhibitors; Intramembrane proteases; Rhomboids; ABP; activity-based probe; BODIPY; boron-dipyrromethylene; DCI; 3,4-dichloro-isocoumarin; DFP; diisopropyl-fluorophosphate; DmRho1; Drosophila melanogaster rhomboid-1; FITC; fluorescei
Keywords: مارپیچ فرابنفش; intramembrane proteolysis/protease; transmembrane helix; presenilin; γ-secretase; rhomboid; conformational dynamics
Keywords: مارپیچ فرابنفش; 2-Nal; 2-naphthylalanine; B0; radio-ligand bound in the absence of competing unlabeled ligand; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; GnRH; gonadotropin releasing hormone; GPCR; G protein-coupled receptor; IP; inositol phosphate;
Keywords: مارپیچ فرابنفش; Sphingolipid; Transmembrane helix; Membrane protein;
Keywords: مارپیچ فرابنفش; Cx; connexin; Vj; transjunctional voltage; NT; amino terminal domain; CT; carboxyl terminal domain; CL; cytoplasmic loop; EL; extracellular loop; TM; transmembrane helix; EM; electron microscopy; Cx32*Cx43E1; Cx32 chimera in which the EL1 of Cx32 is repla
Keywords: مارپیچ فرابنفش; ANTS; 8-aminonaphtalene-1,3,6-trisulfonic acid sodium salt; DID; 1,1â²-dioctadecyl-3,3,3â²,3â²-tetramethyl-indodicarbocyanine; DPX; p-xylene-bis(pyridinium) bromide; GUVs; giant unilamellar vesicles; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; LUVs; large
Keywords: مارپیچ فرابنفش; AC; adenylate cyclase; β-AR; β-adrenergic receptor; CaM; calmoduline; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; DAG; diacylglycerol; DR; dopamine
Proteorhodopsin
Keywords: مارپیچ فرابنفش; BLM; black lipid membrane; bR; bacteriorhodopsin; BPR; blue proteorhodopsin; DNP; dynamic nuclear polarization; GPR; green proteorhodopsin; IR; infrared; pR; proteorhodopsin; SB; Schiff-base; pSB; protonated Schiff-base; TMH; transmembrane helix; Photocyc
Structural patterns of the human ABCC4/MRP4 exporter in lipid bilayers rationalize clinically observed polymorphisms
Keywords: مارپیچ فرابنفش; 6-MP; 6-mercaptopurine; ABC; ATP-binding cassette; ADV; adefovir; AZT; azidothymidine; BLOSUM; blocks substitution matrix; CFTR; cystic fibrosis transmembrane conductance regulator; Chol; cholesterol; cryo-EM; cryo-electronic microscopy; DMAV; dimethylars
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation
Keywords: مارپیچ فرابنفش; Tri-agonist; Signaling cascade; Pancreatic islets; Insulin secretion; G proteins; TRP channels; AC; Adenylyl cyclase; cAMP; Cyclic adenosine monophosphate; ECL; Extracellular loop; EPAC; Exchange protein directly activated by cAMP; FCS; Fetal calf serum;
Comparison of lipid-dependent bilayer insertion of pHLIP and its P20G variant
Keywords: مارپیچ فرابنفش; pH-dependent membrane insertion; Tryptophan fluorescence; Thermodynamics; Conformational switching; Transmembrane helix;
Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii
Keywords: مارپیچ فرابنفش; ABC; ATP-binding cassette; MDR; multi drug resistance; TMDs; transmembrane domains; TMH; transmembrane helix; HUGO; Human Genome Organization; HMM; Hidden Markov Models; ROS; reactive oxygen species; FLC; fluconazole; TRB; terbinafine; AMPB; amphotericin
Molecular cloning and expression analysis of ammonium transporters in tea plants (Camellia sinensis (L.) O. Kuntze) under different nitrogen treatments
Keywords: مارپیچ فرابنفش; N; nitrogen; NUE; nitrogen utilization efficiency; HATS; high-affinity transport system; LATS; low-affinity transport system; DCD; dicyandiamide; AMT; ammonium transporters; CDS; coding sequences; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Vmax; max
W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans
Keywords: مارپیچ فرابنفش; ABC; ATP-binding cassette; TMD; transmembrane domain; NBD; nucleotide binding domain; TMH; transmembrane helix; ICL; intracellular loop; Cdr1p; Candida drug resistance 1 protein; Pdr5p; pleiotropic drug resistance 5 protein; TAP; transporter associated wi
Identification of protein W, the elusive sixth subunit of the Rhodopseudomonas palustris reaction center-light harvesting 1 core complex
Keywords: مارپیچ فرابنفش; RC-LH1; reaction center-light harvesting 1; Rps.; Rhodopseudomonas; Rba.; Rhodobacter; Rsp.; Rhodospirillum; MALDI-TOF; matrix-assisted laser desorption/ionisation-time-of-flight; MS; mass spectrometry; OLE-PCR; overlap-extension polymerase chain reaction
Purification and reconstitution of polyspecific H+/organic cation antiporter human MATE1
Keywords: مارپیچ فرابنفش; MATE; multidrug and toxin extrusion; hMATE1; human MATE1; TEA; tetraethyl ammonium; PQ; paraquat; OC; organic cation; DDTM; n-dodecyl-β-d-thiomaltopyranoside; TM; transmembrane helix; Multidrug and toxic compound extrusion; Organic cation transporter; Pu
A novel in silico minigene vaccine based on CD4+ T-helper and B-cell epitopes of EG95 isolates for vaccination against cystic echinococcosis
Keywords: مارپیچ فرابنفش; HC; hydatid cyst; PSC; protoscolex; CE; cystic echinococcosis; MPMV; multi-potent minigene vaccine; VCA; vaccine candidate antigen; EBV; epitope-based vaccine; BE; B-cell epitope; TE; T-cell epitope; MHC; major histocompatibility; Ag; antigen; Ab; antibod
Conjugative type IV secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM
Keywords: مارپیچ فرابنفش; T4SS; Type IV secretion system; G+; Â Gram-positive; G-; Gram-negative; TMH; Transmembrane helix; CHAP; cysteine, histidine-dependent amidohydrolases/ peptidases; SLT; Soluble lytic transglycosylase; RBS; Ribosomal binding site; LC-MS/MS; Liquid chromatog
Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1
Keywords: مارپیچ فرابنفش; β2-AR; β2-adrenergic receptor; CB1; type 1 cannabinoid receptor; CCM; cholesterol consensus motif; CRAC; cholesterol interaction/recognition amino acid sequence consensus; CT-B; cholera toxin subunit B; GPCR; G-protein-coupled receptor; H8; helix 8; MD;
In vivo selection of heterotypically interacting transmembrane helices: Complementary helix surfaces, rather than conserved interaction motifs, drive formation of transmembrane hetero-dimers
Keywords: مارپیچ فرابنفش; Transmembrane helix; Dimerization; Hetero-dimer; Membrane protein; Protein folding;
The Na+-D-glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer
Keywords: مارپیچ فرابنفش; AMG; α-methyl-D-glucopyranoside; BBB; blood brain barrier; BBM; brush-border membrane; BLM; basolateral membrane; CREB; cAMP response element binding protein; DNJ; 1-deoxynojirimycin; EKA; euglycemic ketoacidosis; GGM; glucose-galactose malabsorption; GI
Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2
Keywords: مارپیچ فرابنفش; GPR64; GPCR; G protein; Molecular pharmacology; Signal transduction; Peptide agonist; 7TM; seven-transmembrane spanning domain; CTF; C-terminal fragment; ECD; extracellular domain; eV; empty vector; DMEM; dulbecco minimum essential medium; ELISA; enzyme-l
Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor
Keywords: مارپیچ فرابنفش; DXQJLXWZLNCEJX-VBCGWZPHSA-N; BODIPY; boron-dipyrromethene; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CHO; Chinese hamster ovary; COMU; [[(Z)-(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-morpholin-4-ylmethylidene]-dimethylazanium hexafluorophosphate;
Effect of monovalent cations on the kinetics of hypoxic conformational change of mitochondrial complex I
Keywords: مارپیچ فرابنفش; A/D; active/de-active transition; BSA; bovine serum albumin; EIPA; 5-(N-Ethyl-N-isopropyl)amiloride; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; HAR; hexaammineruthenium(III)-chloride; Q1; 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-
Geometric rules of channel gating inferred from computational models of the P2X receptor transmembrane domain
Keywords: مارپیچ فرابنفش; P2X; Ion channel; Molecular dynamics; Transmembrane helix; Channel gating; Helical packing
Negative and positive temperature dependence of potassium leak in MscS mutants: Implications for understanding thermosensitive channels
Keywords: مارپیچ فرابنفش; CP; specific heat capacity; GOF; gain-of-function; LOF; loss-of-function; MS; mechanosensitive; NTD; negative temperature dependent; PTD; positive temperature dependent; TM; transmembrane helix; Bacteria; Channel; Mechanosensitive; Potassium; Thermosensit
Intraprotein signal transduction by HAMP domains: A balancing act
Keywords: مارپیچ فرابنفش; TsrE; coli receptors for taxis toward serine; TarE; coli receptors for taxis toward aspartate; HtrII; Natronomonas halobacterial transducer of rhodopsin II; HAMP-1first; HAMP domain of HtrII; HAMP-2second; HAMP domain of HtrII; TM; transmembrane helix; Ad
Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures
Keywords: مارپیچ فرابنفش; GPCR; G protein-coupled receptor; TM; transmembrane; TMH; transmembrane helix; Cα-DAI; difference between the distances between a Cα atom in one helix and the nearest Cα in a second helix in active and inactive states; LJ; Lennard-Jones; RHO; rhodops
The carboxy-terminal tail or the intracellular loop 3 is required for β-arrestin-dependent internalization of a mammalian type II GnRH receptor
Keywords: مارپیچ فرابنفش; GnRH receptor; Internalization; G protein-coupled receptor kinase; β-Arrestin; ERK; DMEM; Dulbecco's modified Eagle medium; EC50; concentration that stimulates half-maximal IP production; ERK; extracellular signal-regulated kinases; FSH; follicle-stimula
New paradigms in GPCR drug discovery
Keywords: مارپیچ فرابنفش; cAMP; 3â²,5â²-cyclic adenosine monophosphate; ADP; adenosine 5â²- diphosphate; GPCR; G protein-coupled receptor; TM; transmembrane helix; ERK; extracellular signal-regulated kinase; T4L; T-4 lysozyme; BRIL; thermostabilized apocytochrome b562; StaRs; s
Weak pulling forces exerted on Nin-orientated transmembrane segments during co-translational insertion into the inner membrane of Escherichia coli
Keywords: مارپیچ فرابنفش; TMH, transmembrane helix; Lep, leader peptidase; aa, amino acid; AP, arrest peptideMembrane insertion; Transmembrane helix; Type 2 membrane protein
Functional response of the small multidrug resistance protein EmrE to mutations in transmembrane helix 2
Keywords: مارپیچ فرابنفش; Ac; acriflavine; EmrE; Escherichia coli small multidrug resistance protein EmrE; Et; ethidium; EtBr; ethidium bromide; MRSA; methicillin resistant Staphylococcus aureus; MV; methyl viologen; PSMR; paired small multidrug resistance; QAC; quaternary ammoniu
Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines
Keywords: مارپیچ فرابنفش; [3H] prazosin; [7-methoxy-3H] prazosin; [3H]-OH-DPAT; 8-[3H-hydroxy-N,N-di-n-propyl-2-aminotetralin]; BPH; benign prostatic hyperplasia; AR; adrenoceptor; 5-HT1A-R; serotonin receptor 1A; D3-R; dopamine D3-receptor; DMEM; Dulbecco's modified Eagle's m
Homo- and hetero-oligomerization of β2-adrenergic receptor in receptor trafficking, signaling pathways and receptor pharmacology
Keywords: مارپیچ فرابنفش; AR; adrenergic receptor; AT1R; angiotensin II type 1 receptor; Bk2R; bradykinin type 2 receptor; BRET; bioluminescence resonance energy transfer; cAMP; cyclic adenosine monophosphate; CB1R; cannabinoid type 1 receptor; Co-IP; co-immunoprecipitation; CREB;
Mutations adjacent to the end of transmembrane helices 6 and 7 independently affect drug efflux capacity of yeast ABC transporter Pdr5p
Keywords: مارپیچ فرابنفش; ATP-binding cassette transporter; Drug susceptibility; Transmembrane helix; ATPase activity; Yeast;
NMR-based approach to measure the free energy of transmembrane helix-helix interactions
Keywords: مارپیچ فرابنفش; NMR; nuclear magnetic resonance; DPC; dodecylphosphocholine; TM; transmembrane; TMD; transmembrane domain; LPR; lipid to protein ratio; CMC; critical micelle concentration; FRET; Forster resonance energy transfer; FGFR3; fibroblast growth factor receptor
Architecture of the hepatitis C virus E1 glycoprotein transmembrane domain studied by NMR
Keywords: مارپیچ فرابنفش; CD; circular dichroism; CPMG; Carr-Purcell-Meiboom-Gil (pulse-train); DHPC; dihexanoylphosphatidylcholine; DPC; dodecyl-phosphocholine; DSS; 4,4-dimethyl-4-silapentane-1-sulfonic acid; DTT; 1,4-dithio-D-threitol; HCV; hepatitis C virus; HSQC; hetero
Global fold and backbone dynamics of the hepatitis C virus E2 glycoprotein transmembrane domain determined by NMR
Keywords: مارپیچ فرابنفش; 4-HTB; 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl benzoate; CPMG; Carr-Purcell-Meiboom-Gill; DSS; 4,4-dimethyl-4-silapentane-1-sulfonic acid; HCV; hepatitis C virus; hetNOE; hetero-nuclear {1H}-15N-nuclear Overhauser effect; HSQC; heteronuclear
Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations
Keywords: مارپیچ فرابنفش; MD; molecular dynamics; 2-AGPI; 2-arachidonoyl-sn-glycero-3-phosphoinositol; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; AEA; N-arachidonoylethanolamine; TMH; transmembrane helix; GPCR; G protein-coupled receptor; EDG; endothelial differentiat
Genetic characterization of E2 region of Chikungunya virus circulating in Odisha, Eastern India from 2010 to 2011
Keywords: مارپیچ فرابنفش; Chikungunya; Genetic analysis; T cell epitope; Positive selection; Transmembrane helix; Structural modeling;
The SLC16 gene family - Structure, role and regulation in health and disease
Keywords: مارپیچ فرابنفش; CHC; α-cyano-4-hydroxycinnamate; DIDS; 4,4â²-di-isothiocyanostilbene-2,2â²-disulphonate; HIF-1α; hypoxia inducible factor-1α; MCT; monocarboxylate transporter; pCMBS; p-chloromercuribenzenesulphonate; PSD; postsynaptic density; TM; transmembrane heli
Nucleotide sequencing and phylogenetic analysis of the 3′ region of glycoprotein C gene of South American bovine herpesviruses 1 and 5
Keywords: مارپیچ فرابنفش; BoHV-1; BoHV-5; gC; Transmembrane helix; Cytoplasmic tail
Involvement of glutamate 97 in ion influx through photo-activated channelrhodopsin-2
Keywords: مارپیچ فرابنفش; afu; arbitrary fluorescent unit; ChR; channelrhodopsin; ChRWR; channelrhodopsin-wide receiver; gin; effective inward conductance; gout; effective outward conductance; Ipeak; effective peak current amplitude; I-V; current-voltage; LED; light-emitting d
A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer
Keywords: مارپیچ فرابنفش; Cofactor binding; Helix interaction; Membrane protein; Protein folding; Protein stability; Transmembrane helix
Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: Role of Proline residue
Keywords: مارپیچ فرابنفش; DPPC; 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; F0; maximum fluorescence emission intensity without quencher; F; and maximum fluorescence emission intensity with the quencher; KSV; Stern-Volmer quenching constant; LPC; Lysophosphatidylcholine (the 1-
Rotor architecture in the yeast and bovine F1-c-ring complexes of F-ATP synthase
Keywords: مارپیچ فرابنفش; yF1c10(I); crystal form I of yeast F1c10 sub-complex; yF1c10(II); crystal form II of yeast F1c10 sub-complex; yF1; yeast F1-ATPase structure; bF1c8; crystal of bovine F1c8 sub-complex; TMH; transmembrane helix; EM; electron microscopy; AMP-PNP; adenylyl-i
The nitrite transport protein NirC from Salmonella typhimurium is a nitrite/proton antiporter
Keywords: مارپیچ فرابنفش; His-tag; polyhistidine tag; IC50; half maximum inhibitory concentration; IPTG; isopropyl-β-d-thiogalactoside; LB; Luria-Bertani growth media; DDM; n-dodecyl-β-d-maltoside; Ni-NTA; nickel-nitrilotriacetic acid; ORF; open reading frame; SDS-PAGE; sodium d