Up-regulation of vitamin B1 homeostasis genes in breast cancer
Keywords: حمل کننده; Transporter; Metabolism; Breast cancer; Vitamin; Thiamine
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Development and automation of a novel NET-PET tracer: [11C]Me@APPI
Keywords: حمل کننده; Transporter; Noradrenaline; PET; Me@APPI; Carbon-11; Radiosynthesis
Rice MtN3/Saliva/SWEET Family Genes and Their Homologs in Cellular Organisms
Keywords: حمل کننده; MtN3/saliva; PQ loop repeat; membrane protein; SWEET; transporter
Application of permeability‐limited physiologically-based pharmacokinetic models: Part II-prediction of p‐glycoprotein mediated drug–drug interactions with digoxin
Keywords: حمل کننده; transporter-mediated drug–drug interactions; P-glycoprotein; ABCB1; MDR1; simulation; digoxin; pharmacokinetics; transporter
Application of permeability-limited physiologically-based pharmacokinetic models: Part I–digoxin pharmacokinetics incorporating P-glycoprotein-mediated efflux
Keywords: حمل کننده; P-glycoprotein; ABCB1; MDR1; simulation; digoxin; IVIVE; pharmacokinetics; transporter
Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system
Keywords: حمل کننده; OCTN1; Transporter; Acetylcholine; Proteoliposomes
Low-affinity copper transporter CTR2 is regulated by copper-sensing transcription factor Mac1p in Saccharomyces cerevisiae
Keywords: حمل کننده; Copper homeostasis; Transporter; Yeast; Transcription factor; Mobilization
The emerging role of transport systems in liver function tests
Keywords: حمل کننده; Organic anion; Transporter; Hepatocyte; Liver function test
Metal-sensing transcription factors Mac1p and Aft1p coordinately regulate vacuolar copper transporter CTR2 in Saccharomyces cerevisiae
Keywords: حمل کننده; Metal homeostasis; Transporter; Yeast; Transcription factor; Mobilization;
BSEP inhibition – In vitro screens to assess cholestatic potential of drugs
Keywords: حمل کننده; TC, taurocholate; GC, glycocholate; TCDC, taurochenodeoxycholate; GCDC, glycochenodeoxycholateBSEP; Transporter; Bile salt; Drug induced liver injury; Cholestasis; Toxicity
Effect of clinical mutations on functionality of the human riboflavin transporter-2 (hRFT-2)
Keywords: حمل کننده; BVVLS; Brown-Vialetto-Van Laere syndrome; hRFT-2; human riboflavin transporter-2; GFP; green fluorescent protein; DsRed2; red fluorescent protein; DsRed2-ER; red fluorescent protein-endoplasmic reticulum; Riboflavin; Intestine; hRFT-2; BVVLS; Transpor
Age-dependent changes in the susceptibility to thiopental anesthesia in mice: Analysis of the relationship to the functional expression of GABA transporter
Keywords: حمل کننده; Thiopental; Anesthesia; GABA; Transporter; Uptake inhibitor;
Molecular basis for differential glycine transporters sensitivity to sanguinarine
Keywords: حمل کننده; Neurotransmitter; Transporter; GlyT1; Sanguinarine; Cysteine;
Nerveless and gutsy: intestinal nutrient sensing from invertebrates to humans
Keywords: حمل کننده; Nutrition; Gut; Receptor; Transporter; Drosophila elegans;
Mutations of FLVCR1 in posterior column ataxia and retinitis pigmentosa result in the loss of heme export activity
Keywords: حمل کننده; FLVCR1; PCARP; Heme; Transporter
Synthesis of [11C]dehydropravastatin, a PET probe potentially useful for studying OATP1B1 and MRP2 transporters in the liver
Keywords: حمل کننده; Positron emission tomography; C-C Coupling; Rapid reaction; Transporter;
The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease
Keywords: حمل کننده; TEA; tetraethylammonium; PLP; pyridoxal 5-phosphate; ANTP; adenosine 5â²-(β,γ-imido)triphosphate; MTSET; sodium (2-(trimethylammonium)ethyl methanethiosulfonate); p-OHMB; p-hydroxymercuribenzoate; NEM; N-ethylmaleimide; OCTN1; Transporter; Reconstituti
Oral drug delivery utilizing intestinal OATP transporters
Keywords: حمل کننده; Absorption; OATP; Transporter; Drug–fruit juice interaction; Genetic polymorphism
Effects of third trimester-equivalent ethanol exposure on Cl− co-transporter expression, network activity, and GABAergic transmission in the CA3 hippocampal region of neonatal rats
Keywords: حمل کننده; Fetal alcohol syndrome; Development; Transporter; GABA; Synaptic
Up-regulation of l-Type Amino Acid Transporter 1 (LAT1) in Cultured Rat Retinal Capillary Endothelial Cells in Response to Glucose Deprivation
Keywords: حمل کننده; inner blood-retina barrier; retinopathy; transporter; promoter; amino acid
Function and regulation of taurine transport in Müller cells under osmotic stress
Keywords: حمل کننده; Müller cells; Retina; Transporter; Taurine
Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubicin-bound block copolymers
Keywords: حمل کننده; DDS; drug delivery system; PEG; polyethyleneglycol; RES; reticuloenodothelial system; EPR; enhanced permeability and retention; Dox; doxorubicin; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; DLS; dynamic light scattering; AFM; atomic
Overview of glutamatergic neurotransmission in the nervous system
Keywords: حمل کننده; Glutamate; NMDA; AMPA; EAAT; Transporter; Metabotropic; Psychiatry
Serotonin as a homeostatic regulator of lactation
Keywords: حمل کننده; Serotonin; Mammary gland; Receptor; Transporter; Milk yield
Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish
Keywords: حمل کننده; Behavior; Zebrafish; Glutamate; Transporter; Hindbrain; Spinal cord
A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport
Keywords: حمل کننده; VMAT2; Slc18a2; Monoamine; Dopamine; Transporter;
Establishment of a new conditionally immortalized cell line from human brain microvascular endothelial cells: A promising tool for human blood–brain barrier studies
Keywords: حمل کننده; The blood–brain barrier; Brain microvascular endothelial cell; In vitro BBB model; Conditionally immortalized cell; Tight junction; Transporter
Intracellular trafficking mechanism, from intracellular uptake to extracellular efflux, for phospholipid/cholesterol liposomes
Keywords: حمل کننده; Liposomes; Intracellular trafficking; Endosomal/lysosomal escape; ER-to-Golgi transport; Transporter;
Functional expression of carnitine/organic cation transporter OCTN1 in mouse brain neurons: Possible involvement in neuronal differentiation
Keywords: حمل کننده; ATRA; all-trans retinoic acid; CL; cerebellum; CX; cerebral cortex; DIV; days in vitro; DMEM; Dulbecco's modified Eagle's medium; ERGO; ergothioneine; FBS; fetal bovine serum; GAP43; growth-associated protein 43; HC; hippocampus; HO-1; heme oxygenase-
Insights from molecular dynamics: The binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters
Keywords: حمل کننده; Neurotransmitter; Transporter; DAT; LeuT; Leucine; Dopamine; Amphetamine; Cocaine; Molecular dynamics; MCTI; RAMD
The role of osmotic polysorbitol-based transporter in RNAi silencing via caveolae-mediated endocytosis and COX-2 expression
Keywords: حمل کننده; RNAi silencing; Polysorbitol; Transporter; Caveolae-mediated endocytosis; Cav-1; COX-2
Charting the travels of copper in eukaryotes from yeast to mammals
Keywords: حمل کننده; Copper; Homeostasis; Yeast; Mammal; Transporter; Chaperone
Psychiatric Pharmacogenomics in Pediatric Psychopharmacology
Keywords: حمل کننده; Pharmacogenomics; Psychopharmacology; Pediatric; Metabolism; Dopamine; Serotonin; Transporter; Receptor;
Membrane transport metabolons
Keywords: حمل کننده; ABC; ATP-binding cassette; AE1; anion exchanger 1; CAII; carbonic anhydrase II; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GLUT; glucose transporter; MFS; major facilitator superfamily of transporters; PFK; phosphofructokinase; SLC; solute carrier;
Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters
Keywords: حمل کننده; PCR, polymerase chain reaction; RNAi, RNA interferenceTrypanosoma brucei; Melarsoprol; Eflornithine; Amino acid; Transporter; Drug resistance
GLAST stability and activity are enhanced by interaction with the PDZ scaffold NHERF-2
Keywords: حمل کننده; Glia; Astrocyte; Neurodegeneration; Excitatory amino acid; Transporter; Receptor;
Expressions of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells
Keywords: حمل کننده; Dendritic cell; Lung; Multidrug resistance protein 1; Multidrug resistance-associated protein 1; Transporter;
Role of FOXA and Sp1 in mitochondrial acylcarnitine carrier gene expression in different cell lines
Keywords: حمل کننده; CAC; carnitine/acylcarnitine carrier; FOXA; forkhead box A; Sp1; stimulating protein 1; PPRE; peroxisome proliferator-activated receptor element; ChIP; chromatin immunoprecipitation; LUC; luciferase; siRNA; small interfering RNA; wtFOXA, wtSp1a and wtSp1b
Expression of the SNAT2 amino acid transporter during the development of rat cerebral cortex
Keywords: حمل کننده; Transporter; SNAT2; mRNA; Protein; Development
Estimation of Michaelis–Menten constant of efflux transporter considering asymmetric permeability
Keywords: حمل کننده; Passive diffusion; Transporter; Asymmetric; Efflux; Mechanistic model
Differential effect of the benzophenanthridine alkaloids sanguinarine and chelerythrine on glycine transporters
Keywords: حمل کننده; Neurotransmitter; Transporter; Glycine; Protein kinase C; PKC; GlyT1; GlyT2; Chelidonium majus; Inhibitor; Pain; Chelerythrine; Sanguinarine; Benzophenanthridine; Alkaloid; Ouabain
Regulatory role of the dopamine and norepinephrine transporters in pentylenetetrazol-kindled mice: Association with effect of antidepressants
Keywords: حمل کننده; Kindling; Atomoxetine; Depressive-like state; Norepinephrine; Transporter; Epilepsy
Expression of an Arabidopsis Ca2+/H+ antiporter CAX1 variant in petunia enhances cadmium tolerance and accumulation
Keywords: حمل کننده; Cadmium; CAX; Petunia; Phytoremediation; Transporter
A tool for the qualitative comparison of membrane-embedded and detergent-solubilized membrane protein structures in projection
Keywords: حمل کننده; Electron crystallography; Membrane protein; Projection structure; Transmission electron microscopy; Transporter; Two-dimensional crystal; X-ray crystallography; gBF; global B-factor; EC; electron crystallography; PDB; Protein Data Bank; PS; projection str
Comparison of Drug Permeabilities Across the Blood–Retinal Barrier, Blood–Aqueous Humor Barrier, and Blood–Brain Barrier
Keywords: حمل کننده; blood–retinal barrier; blood–aqueous barrier; blood–brain barrier; transporter; P-glycoprotein
Interaction of tyrosine 151 in norepinephrine transporter with the 2β group of cocaine analog RTI-113
Keywords: حمل کننده; Dopamine; Norepinephrine; Transporter; Structure; Cocaine; Analog; Binding site; Computer modelingAquifex aeolicus leucine transporter, (LeuTAa); dopamine, (DA); dopamine transporter, (DAT); half maximal inhibition constant, (IC50); norepinephrine, (NE);
Enhancement of Zidovudine Transfer to Molt-4 Cells, a Human T-Cell Model, by Dehydroepiandrosterone Sulfate
Keywords: حمل کننده; antiretroviral drug; permeation enhancers; AZT; transporter; drug targeting; distribution; drug interactions
Natural and engineered coding variation in antidepressant-sensitive serotonin transporters
Keywords: حمل کننده; serotonin; antidepressant; transporter; cocaine; autism; p38 mitogen-activated protein kinase; SERT; serotonin transporter; SSRI; 5-HT selective reuptake inhibitors;
Simulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfate
Keywords: حمل کننده; Simulation; Transporter; Caco-2 cells; Estrone-3-sulfate; Brij35; Erythrosine
Spatial expression and functionality of drug transporters in the intact lung: Objectives for further research
Keywords: حمل کننده; Transporter; Lung; Pulmonary; Delivery; ATP; P-glycoprotein; MRP; BCRP; OAT; OATP; OCT; OCTN; Pharmacokinetics