Keywords: تریپتوفان 2،3-دی اکسیژناز; HC; healthy controls; MDD; major depressive disorder; SOD; severity of depression; SCID; Structured Clinical Interview for DSM-IV-TR; BDI-II; Beck Depression Inventory-Second Edition; LC-MS; liquid chromatography-mass spectrometry; Total-C; total-choleste
مقالات ISI تریپتوفان 2،3-دی اکسیژناز (ترجمه نشده)
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Keywords: تریپتوفان 2،3-دی اکسیژناز; Immune escape; Crystal structures; IDO1 inhibitors; Cancer immunotherapy; KP; kynurenine pathway; Trp; tryptophan; KYN; kynurenine; IDO1; indoleamine 2,3-dioxygenase 1; IDO2; indoleamine 2,3-dioxygenase 2; TDO; tryptophan 2,3-dioxygenase; IFN; interferon;
Keywords: تریپتوفان 2،3-دی اکسیژناز; Albumin; Glucose; Indoleamine 2,3-dioxygenase; Non-esterified fatty acids; Tryptophan 2,3-dioxygenase; 3-HK; 3-Hydroxykynurenine; 3-HAA; 3-hydroxyanthranilic acid; 5-HT; 5-hydroxytryptamine or serotonin; IDO; Indoleamine 2,3-dioxygenase; KA; kynurenic aci
Keywords: تریپتوفان 2،3-دی اکسیژناز; Diet; Amino Acid; Kynurenine; Inflammation; Anti-Inflammatory; AHR; aryl hydrocarbon receptor; AUC; area under the curve; CAI; Clinical Activity Index for Ulcerative Colitis; CARD9; caspase recruitment domain family member 9; CD; Crohn's disease; CDAI;
Keywords: تریپتوفان 2،3-دی اکسیژناز; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; 3-HK; 3-hydroxykynurenine; 5-HT; serotonin; IDO; indoleamine 2,3-dioxygenase; KATs; kynurenine aminotransferases; KMO; kynurenine 3-monooxygenase; KYNA; kynurenic acid; KYNU; kynureninase; QUIN; quinolinic aci
Keywords: تریپتوفان 2،3-دی اکسیژناز; Allopurinol; Depression; Fluoxetine; Forced swimming test; Serotonin; Tryptophan 2,3-dioxygenase
Keywords: تریپتوفان 2،3-دی اکسیژناز; CNS; central nervous system; INS-1; insulin secreting β-cell line originated from a rat insulinoma; GK rat; Goto-Kakizaki rat; NOD mouse; non-obese diabetic mouse; TKP; tryptophan/kynurenine pathway; Trp; tryptophan; KYN; kynurenine; 3HK; 3-OH-kynureni
Keywords: تریپتوفان 2،3-دی اکسیژناز; TDO; human tryptophan 2,3-dioxygenase; IDO; human indoleamine 2,3-dioxygenase; KMO; kynurenine 3-monoxygenase; NCI; National Cancer Institute USA; Tryptophan 2,3-dioxygenase; Cancer; Kynurenine pathway;
Keywords: تریپتوفان 2،3-دی اکسیژناز; α1AT; α-1-antitrypsin; BM-MSCs; bone-marrow mesenchymal stem cells; COX1; subunit I of the cytochrome c oxidase; COX2; subunit II of the cytochrome c oxidase; COX4; subunit IV of the cytochrome c oxidase; DRP1; dynamin-related protein 1; ECAR; extracell
Keywords: تریپتوفان 2،3-دی اکسیژناز; MDD; major depressive disorder; BD; bipolar disorder; ASA; acetyl-salicylic acid; WHO; World Health Organization; TCAs; tricyclic antidepressants; MAOIs; monoamine oxidase inhibitors; SSRIs; selective serotonin reuptake inhibitors; PAMPs; pathogen associa
The molecular aspects of oxidative & nitrosative stress and the tryptophan catabolites pathway (TRYCATs) as potential causes of depression
Keywords: تریپتوفان 2،3-دی اکسیژناز; BDNF; brain-derived neurotrophic factor; CAT; catalase; CIRS; compensatory (anti)inflammatory reflex system; CoQ10; coenzyme Q10; DD; depressive disorders; GPx; glutathione peroxidise; GR; glutathione reductase; GSH; glutathione; HDL-c; high-density lipop
Metabolic pathway interruption: CRISPR/Cas9-mediated knockout of tryptophan 2,3-dioxygenase in Tribolium castaneum
Keywords: تریپتوفان 2،3-دی اکسیژناز; CRISPR; Ommochrome; Tryptophan 2,3-dioxygenase; Vermilion; Tribolium castaneum; Insect eye pigment;
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors
Keywords: تریپتوفان 2،3-دی اکسیژناز; Indoleamine 2,3-dioxygenase 1; Cancer immunotherapy; Naphthoquinone derivatives; Tryptophan 2,3-dioxygenase;
Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition
Keywords: تریپتوفان 2،3-دی اکسیژناز; Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure
Regular ArticleHypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency
Keywords: تریپتوفان 2،3-دی اکسیژناز; TDO; tryptophan 2,3-dioxygenase; ITC; isothermal titration calorimetry; l-Trp; l-tryptophan; 5-HIAA; 5-hydroxyindoleacetic acid; αMTrp; α-methyltryptophan; Hypertryptophanemia; Hyperserotoninemia; Tryptophan 2,3-dioxygenase; TDO2;
Nitrobenzofurazan derivatives of Nâ²-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1
Keywords: تریپتوفان 2،3-دی اکسیژناز; Nâ²-hydroxyamidines; Mechanism-based drug design; IDO1 inhibition; High selectivity; Low cytotoxicity; IDO1; indoleamine 2,3-dioxygenase 1; TDO; tryptophan 2,3-dioxygenase; L-Trp; L-tryptophan; HTS; High throughput screening; UV-Vis; ultraviolet-visi
Biosynthesis of N,N-dimethyltryptamine (DMT) in a melanoma cell line and its metabolization by peroxidases
Keywords: تریپتوفان 2،3-دی اکسیژناز; AFMK; N-acetyl-N-formyl-5-methoxy-kynuramine; AMK; N-acetyl-5-metoxy-kynuramine; DMEM; Dulbecco' modified eagle medium; DMFK; N,N-dimethyl-N-formyl-kynuramine; DMK; N,N-dimethyl-quinuramine; DMSO; dimethyl sulfoxide; DMT; N,N-dimethyltryptamine; DPI; di
Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A
Keywords: تریپتوفان 2،3-دی اکسیژناز; IDO1; indoleamine 2,3-dioxygenase; TDO; tryptophan 2,3-dioxygenase; NHDF; normal fibroblast cell lines; MTT; (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; EDTA; ethylenediaminetetraacetic acid; IMAC; immobilized metal ion affinity chromat
Effect of systemic kynurenine on cortical spreading depression and its modulation by sex hormones in rat
Keywords: تریپتوفان 2،3-دی اکسیژناز; CSD; cortical spreading depression; DC; direct current; FHM; familial hemiplegic migraine; HPLC; high performance liquid chromatography; IDO; indoleamine 2,3-dioxygenase; KAT; kynurenine aminotransferases; KYNA; Kynurenic acid; L-KYN; l-kynurenine; nAChR;
Modulation of cytochrome P450 gene expression in primary hepatocytes on various artificial extracellular matrices
Keywords: تریپتوفان 2،3-دی اکسیژناز; ASGPR; asialoglycoprotein receptor; BAL; bioartificial liver; BSA; bovine serum albumin; CYP; cytochrome P450; DAPI; 4â²,6-diamidino-2-phenylindole; E-cad-Fc; E-cadherin-IgG Fc; ECM; extracellular matrix; EGF; epidermal growth factor; Mrp2; multidrug res
Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors
Keywords: تریپتوفان 2،3-دی اکسیژناز; ALDPC; adult liver-derived progenitor cells; iPS; induced pluripotent stem cells; LETF; liver enriched transcription factors; LD; liver differentiation medium; HBM; hepatocyte basal medium; MM; maintenance medium; ESC; embryonic stem cells; Foxa2; forkhea
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder
Keywords: تریپتوفان 2،3-دی اکسیژناز; Psychosis; Gene-gene interactions; Metabolic; Niacin receptor; Tryptophan 2,3-dioxygenase;
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli
Keywords: تریپتوفان 2،3-دی اکسیژناز; Anopheles gambiae; Tryptophan metabolism; Kynurenine pathway; Tryptophan 2,3-dioxygenase; Recombinant enzyme
Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels
Keywords: تریپتوفان 2،3-دی اکسیژناز; Tolmetin; Sulindac; Tryptophan 2,3-dioxygenase; Serotonin; Dopamine; Melatonin; Parkinson's disease; NSAIDS