Acetylation of histone deacetylase 6 by p300 attenuates its deacetylase activity
Keywords: توبولین; HDAC6; p300; Acetylation; Tubulin; Sp1;
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Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness
Keywords: توبولین; Taxol; Tubulin; Cancer invasiveness; NaV1.5; Metastasis; MDA-MB-231; MDA-MB-468;
Evaluation of biosensor surfaces for the detection of microtubule perturbation
Keywords: توبولین; Dual polarization interferometry; Resonant mirror; Tubulin; Microtubules
Effect of different cryopreservation protocols on cytoskeleton and gap junction mediated communication integrity in feline germinal vesicle stage oocytes
Keywords: توبولین; Cat; Oocyte; Banking; Vitrification; Slow freezing; Gap junctions; Actin; Tubulin; Cytoskeleton; Meiosis
ZNRF1 interacts with tubulin and regulates cell morphogenesis
Keywords: توبولین; ZNRF1; Tubulin; Ubiquitin; RING finger; Zinc finger
Synthesis and activity evaluation of phenylurea derivatives as potent antitumor agents
Keywords: توبولین; Phenylurea; Anticancer; Structure–activity relationship; Tubulin; Mitotic arrest
Familial amyotrophic lateral sclerosis-linked mutant SOD1 aberrantly interacts with tubulin
Keywords: توبولین; SOD1; ALS; Tubulin; Interaction
Modification of the cytosolic regions of GABA transporter GAT1 by calpain
Keywords: توبولین; Calpain; Neurotransmitter; Transporters; GABA; GAT1; PDZ; Tubulin; Actin; MUPP1;
A label-free mass spectrometry method for the quantification of protein isotypes
Keywords: توبولین; Label-free quantification; Mass spectrometry; Targeted proteomic analysis; Tubulin isotype quantification; Tubulin;
Pattern of tau isoforms expression during development in vivo
Keywords: توبولین; Development; Neuronal differentiation; Neuronal plasticity; Neocortex; Cerebellum; Tubulin
Evolution of cytomotive filaments: The cytoskeleton from prokaryotes to eukaryotes
Keywords: توبولین; Actin; Tubulin; FtsZ; MreB; WACA; Cytomotive filaments; ParM; Septins
Demonstration of microtubule-like structures formed with (â)-rhazinilam from purified tubulin outside of cells and a simple tubulin-based assay for evaluation of analog activity
Keywords: توبولین; Tubulin; (â)-rhazinilam; Rhazinilam analogs; Microtubule morphology; GTP; Sedimentation assay; MCF-7 human breast carcinoma cells; Spiral morphology of tubulin polymer; Vinblastine; Glutamate;
Binding affinity of fluorochromes and fluorescent proteins to Taxol™ crystals
Keywords: توبولین; Taxol crystals; Spherulites; Tubulin; Fluorochromes; Binding energy; Computational docking
Nuclear maturation and structural components of nonhuman primate cumulus–oocyte complexes during in vivo and in vitro maturation
Keywords: توبولین; Rhesus monkey; tubulin; actin; zona pellucida; ovary; spindle
Experimental epothilone B neurotoxicity: Results of in vitro and in vivo studies
Keywords: توبولین; Epothilone B; In vivo; In vitro; Toxicity; Peripheral neuropathy; Tubulin;
Total synthesis and biological evaluation of novel C2–C6 region analogues of dictyostatin
Keywords: توبولین; Macrolide; Antitumour; Tubulin; Total synthesis
Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives
Keywords: توبولین; Myoseverin; Pyrazolo[1,5-a]-1,3,5-triazine; Tubulin; Cancer
Evidence for a distinct ligand binding site on tubulin discovered through inhibition by GDP of paclitaxel-induced tubulin assembly in the absence of exogenous GTP
Keywords: توبولین; Tubulin; GDP; Paclitaxel; Nucleotide binding sites; ATP; Microtubule-associated proteins;
Prefoldins 3 and 5 Play an Essential Role in Arabidopsis Tolerance to Salt Stress
Keywords: توبولین; Prefoldins; cytoskeleton; tubulin; actin; microtubule; salt tolerance; Arabidopsis
Comparative study of cyanotoxins affecting cytoskeletal and chromatin structures in CHO-K1 cells
Keywords: توبولین; Microcystin; Cylindrospermopsin; Actin; Tubulin; Fluorescence microscopy; Apoptosis; Necrosis
Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity
Keywords: توبولین; GMPCPP; guanylyl-(α,β)-methylene-diphosphonate; CRMP-2; Tubulin; GTPase activity; Regulation; Microtubule;
Mass spectral characterization of organophosphate-labeled lysine in peptides
Keywords: توبولین; Mass spectrometry; Organophosphate esters; Chlorpyrifos oxon; Diisopropylfluorophosphate; Serum albumin; Keratin; Tubulin; Actin; Transferrin;
Isocombretastatins A: 1,1-Diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds
Keywords: توبولین; Tubulin; Combretastatins; Phenstatins; Colchicine; Antitumour; Cytotoxicity; Antimitotic
15-Deoxi-Δ12,14-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest
Keywords: توبولین; MS, mass spectrometry; MT, microtubules; PPARγ, peroxisome proliferators-activated receptor γ; RSG, rosiglitazone; 15d-PGJ2, 15-deoxi-Δ12,14-prostaglandin J215d-PGJ2; Cell death; Cytoskeleton; Mitosis; Tubulin; Cancer
Molecular cold-adaptation of protein function and gene regulation: The case for comparative genomic analyses in marine ciliated protozoa
Keywords: توبولین; Adaptive evolution; Antarctica; Southern Ocean; Psychrophilic; Tubulin; Heat-shock proteins
Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent
Keywords: توبولین; Top I, topoisomerase I; CPT, camptothecin; PLDBs, protein-linked DNA breaksTopoisomerase I; Tubulin; Dual inhibitor
Histone deacetylase inhibitors that target tubulin
Keywords: توبولین; Epigenetics; Histone deacetylases; HDAC6; Sirtuin; Tubulin
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones
Keywords: توبولین; Chalcone; Tubulin; Combretastatin; Colchicine; Podophyllotoxin; Antivascular; Anticancer; Docking
Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity
Keywords: توبولین; Chalcone; Combretastatin; Tubulin; Antivascular; Anticancer; Colchicine; SD400
Axonal mRNAs: Characterisation and role in the growth and regeneration of dorsal root ganglion axons and growth cones
Keywords: توبولین; Axon growth; Axon regeneration; Axonal transport; Axon guidance; Growth cone; mRNA; Translation; Actin; Integrins; Tubulin
The paclitaxel site in tubulin probed by site-directed mutagenesis of Saccharomyces cerevisiae β-tubulin
Keywords: توبولین; Tubulin; Paclitaxel; Mutagenesis; Saccharomyces cerevisiae
Microtubule dynamics regulated by stathmin
Keywords: توبولین; Stathmin; Monte Carlo; Gradient region; Catastrophe; Rescue; Tubulin
Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates
Keywords: توبولین; MRI contrast agents; Gd(III) complexes; Tubulin; Thyroxine binding globulin
Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives
Keywords: توبولین; Tubulysin; Tubulin; Anticancer agents; Cytotoxicity; Natural products
Total synthesis and biological evaluation of potent analogues of dictyostatin: Modification of the C2–C6 dienoate region
Keywords: توبولین; Total synthesis; Macrolide; Anticancer; Tubulin
Inhibition of tubulin polymerization by select alkenyldiarylmethanes
Keywords: توبولین; Cytotoxicity; Tubulin; HIV; Alkenyldiarylmethane; ADAM; Antiviral; Anticancer; Anti-HIV;
Fasciola hepatica expresses multiple α- and β-tubulin isotypes
Keywords: توبولین; Fasciola hepatica; Trematode; Tubulin; Drug resistance; Isotypes;
Specific reaction of α,β-unsaturated carbonyl compounds such as 6-shogaol with sulfhydryl groups in tubulin leading to microtubule damage
Keywords: توبولین; D-PBS; Dulbecco's phosphate-buffered saline; DTNB; 5,5â²-dithiobis-nitrobenzoic acid; DTT; dithiothreitol; 2-ME; 2-mercaptoethanol; GSH; glutathione; NBD-PZ; 4-nitro-7-piperazino-2,1,3-benzoxadiazole; SDS-PAGE; sodium dodecyl sulphate-polyacrylamid
Flightless-I, a gelsolin family member and transcriptional regulator, preferentially binds directly to activated cytosolic CaMK-II
Keywords: توبولین; CaMK-II; Ca2+/CaM-dependent protein kinase type II; CaM; calmodulin; Fli-I; flightless-I; Tcf/Lef; T-cell factor/lymphoid-enhancer binding factor-1; GFP; green fluorescent protein; AIP; auto-inhibitory peptide; β-Catenin; CaMK-II; Mass spectrometry; Flig
The involvement of Src family kinases (SFKs) in the events leading to resumption of meiosis
Keywords: توبولین; Calcium; MPF; c-Src; Fyn; c-Yes; CaMKII; Tubulin
Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor
Keywords: توبولین; Heteroarylcoumarin; CA-4 analogues; Cytotoxicity; Tubulin; Structure–activity
Tubulin superfamily genes in Tribolium castaneum and the use of a Tubulin promoter to drive transgene expression
Keywords: توبولین; Tribolium; Tubulin; Promoter; PiggyBac; EGFP; Vermilion; Transgene
Impairment of microtubule system increases α-synuclein aggregation and toxicity
Keywords: توبولین; α-Synuclein; Amyloid; Microtubule; Tubulin; Yeast model;
NGF-induced neurite outgrowth of PC12 cells in the presence of phosphatidylcholine hydroperoxides: Implication for ageing
Keywords: توبولین; Oxidative stress; Phosphatidylcholine hydroperoxide; Membrane lipid; Microtubule; Tubulin;
Exploring vascular dysfunction caused by tirapazamine
Keywords: توبولین; Carbogen; NOS; Tirapazamine; Vasculature; Tubulin; SiHa; HCT-116; SCCVII;
Involvement of cytoskeleton in Junín virus entry
Keywords: توبولین; Junín virus; Cytoskeleton; Actin; Tubulin
Safety of repeated administrations of ixabepilone given as a 3-hour infusion every other week in combination with irinotecan in patients with advanced malignancies
Keywords: توبولین; Combination chemotherapy; CPT11; Epothilones; Neurotoxicity; Tubulin;
Structure–activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications
Keywords: توبولین; Antiproliferative; Inhibitors; Structure–activity relationship; Tubulin
Induced electrostatic charge in poleward motion of chromosomes during mitosis
Keywords: توبولین; Electrostatic force; Mitosis; Chromosome motility; Tubulin; Anaphase;
Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation
Keywords: توبولین; Tubulin; Antimitotic; Cytotoxic; Combretastatins; Phenstatins; Naphthalene; Analogues; Docking