Cytoskeletal mechanisms for platelet production
Keywords: توبولین; Megakaryocyte; Proplatelet; Platelet; Tubulin; Microtubules; Dynein; Actin; Membrane skeleton
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Effects of α-substitutions on structure and biological activity of anticancer chalcones
Keywords: توبولین; Anticancer; Chalcone; Tubulin; Fluorine; Fluorination
Activation of the Escherichia coli cell division protein FtsZ by a low-affinity interaction with monovalent cations
Keywords: توبولین; FtsZ; Monovalent cations; Bacterial cell division; Protein polymerization; GTPase; Tubulin
Tubulin nitration in human gliomas
Keywords: توبولین; ES/MS; electrospray mass spectrometry; ES/MS/MS; electrospray tandem mass spectrometry; HPLC; high-performance liquid chromatography; LC/MS/MS; liquid chromatography-electrospray tandem mass spectrometry; MALDI-TOF; matrix-assisted laser desorption ioni
Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts
Keywords: توبولین; Microtubules; Mitosis; Xenopus egg extracts; Phosphocellulose column; Tubulin; Microtubule-associated proteins; Op18/Stathmin
Novel imidazole-based combretastatin A-4 analogues: Evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin
Keywords: توبولین; Cytotoxicity; Combretastatin A-4; Colchicine; Imidazoles; Tubulin; Molecular modeling; Antitumor activity
Ascorbic acid reduction of microtubule protein disulfides and its relevance to protein S-nitrosylation assays
Keywords: توبولین; Peroxynitrite; Ascorbic acid; Tubulin; Microtubule-associated proteins; Tau; MAP2; Cysteine oxidation; Disulfide bonds; S-nitrosylation; Biotin switch
In vitro oxidative metabolism study of (−)-rhazinilam
Keywords: توبولین; Rhazinilam; Metabolism; Tubulin; CYP
Interaction of hepatitis C virus F protein with prefoldin 2 perturbs tubulin cytoskeleton organization
Keywords: توبولین; Hepatitis C virus; F protein; Tubulin; Cytoskeleton; Prefoldin 2; Yeast two-hybrid system; Aberrant organization; Interaction; Replication; Persistence;
Synthesis and biological activity of 8-azapurine and pyrazolo[4,3-d]pyrimidine analogues of myoseverin
Keywords: توبولین; Myoseverin; Purine; Tubulin; Cyclin-dependent kinase; Cytoskeleton
Direct interaction of Bcl-2 proteins with tubulin
Keywords: توبولین; Tubulin; Microtubule assembly; Bcl-2; Bid; Bax; Bak; Tubulin S; BH3 domain
Strategy of macromolecular grafting onto a gold substrate dedicated to protein–protein interaction measurements
Keywords: توبولین; Self-assembled monolayer (SAM); DPDPB; Protein immobilization; Surface plasmon resonance (SPR); GEC1; Tubulin
Purification of tubulin from limited volumes of cultured cells
Keywords: توبولین; Tubulin; Microtubule; Purification; HeLa
G protein activation is prerequisite for functional coupling between Gα/Gβγ and tubulin/microtubules
Keywords: توبولین; G protein; Tubulin; Microtubules; Signal transduction; GTP binding protein; Cytoskeleton; GTPase
Leishmania tarentolae: Purification and characterization of tubulin and its suitability for antileishmanial drug screening
Keywords: توبولین; Leishmania; Tubulin; Dinitroaniline; Drug discovery; DEAE, diethylaminoethyl; DMSO, dimethyl sulfoxide; EGTA, ethyleneglycol-bis(β-aminoethyl ether); GB-II-5, N1-phenyl-3,5-dinitro-N4,N4-di-n-propylsulfanilamide; GB-II-150, N1-phenyl-3,5-dinitro-N4,N4-di-
Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation
Keywords: توبولین; Taxol; Paclitaxel; Tubulin; Cytotoxicity; Molecular modeling; Synthesis; Olefin metathesis
Prion protein inhibits microtubule assembly by inducing tubulin oligomerization
Keywords: توبولین; Prion protein; Tubulin; Microtubules; Oligomerization; Electron microscopy
Membranous and structural damage that occur during cryopreservation of human sperm may be time-related events
Keywords: توبولین; Semen cryopreservation; tubulin; P34H; cryoinjury
Laminin activates CaMK-II to stabilize nascent embryonic axons
Keywords: توبولین; CaM kinase II; Actin; Growth cone; Integrin; Laminin; Tubulin
Immunolocalization of cytoskeletal components in the tegument of the 3-week-old juvenile and adult Fasciola gigantica
Keywords: توبولین; Fasciola gigantica; Schistosoma mansoni; Tegument; Cytoskeleton; Tubulin; Actin; Cytokeratin
Control mechanisms of tubulin gene expression in Trypanosoma cruzi
Keywords: توبولین; Trypanosoma cruzi; Tubulin; Gene regulation; Untranslated region
Actomyosin-dependent microtubule rearrangement in lysophosphatidic acid-induced neurite remodeling of young cortical neurons
Keywords: توبولین; Lysophosphatidic acid; Tubulin; Actin; Myosin; Neurofilament; Neurite
Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides
Keywords: توبولین; Leishmania; Trypanosome; Chemotherapy; Tubulin; Dinitroaniline
Antibodies that recognize α- and β-tubulin inhibit in vitro growth of the fish parasite Trypanosoma danilewskyi, Laveran and Mesnil, 1904
Keywords: توبولین; Trypanosoma danilewskyi; Protozoa; Tubulin; Growth; Immunity; Excretory–secretory products; Fish
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents
Keywords: توبولین; Combretastatin; Tubulin; Inhibitors of tubulin assembly; Anti-cancer; Pro-drug constructs; Vascular disrupting agents
Synthesis and anti-tubulin evaluation of chromone-based analogues of combretastatins
Keywords: توبولین; Flavones; Citrus flavonoids; Combretastatins; Tubulin;
Cell signaling pathways to αB-crystallin following stresses of the cytoskeleton
Keywords: توبولین; Cytoskeleton; Actin; Tubulin; Intermediate filaments; MAP kinases; p38; Stress; sHSP; αB-crystallin
Substantial CCT activity is required for cell cycle progression and cytoskeletal organization in mammalian cells
Keywords: توبولین; Chaperonin; Actin; Tubulin; Protein folding
Synthesis and biological evaluation of (3,4,5-trimethoxyphenyl)indol-3-ylmethane derivatives as potential antivascular agents
Keywords: توبولین; Combretastatin A-4; Tubulin; 3-Aroylindole; EA·hy 926 endothelial cells
Dual effects of staurosporine on A431 and NRK cells: Microfilament disassembly and uncoordinated lamellipodial activity followed by cell death
Keywords: توبولین; Actin; A431 cells; Apoptosis; ADF/cofilin; NRK cells; Tubulin; VimentinADF, actin-depolymerising factor; MLCK, myosin light chain kinase; DTT, dithiothreitol; FCS, foetal calf serum; FITC, fluorescein thioisocyanate; Hepes; 4-(hydroxyethyl)-1-piperazineet
A reporter-assisted mutagenesis screen using α1-tubulin-GFP transgenic zebrafish uncovers missteps during neuronal development and axonogenesis
Keywords: توبولین; Tubulin; Transgenic; Mutagenesis; Neurogenesis; Cell cycle exit; Axonal branching; Zebrafish
Analysis of cytoskeletal and motility proteins in the sea urchin genome assembly
Keywords: توبولین; Sea urchin; Cytoskeleton; Actin; Myosin; Intermediate filament; Tubulin; Microtubule; Microfilament; MAP; Dynein; Kinesin; Motility; Genome
Synthesis and biological evaluation of B-ring analogues of (â)-rhazinilam
Keywords: توبولین; Rhazinilam; Tubulin; Cytotoxicity; Structure-activity relationships;
Synthetic approach to enyne and enediyne analogues of anticancer agents
Keywords: توبولین; Combretastatin A-4; Enynes; Enediynes; Tubulin; Polymerization; Cytotoxicity;
Expression of HSG is essential for mouse blastocyst formation
Keywords: توبولین; HSG; Mitochondria; Oocytes; Preimplantation embryos; Tubulin;
Tubulin-polymerization inhibitors derived from thalidomide
Keywords: توبولین; Thalidomide; Tubulin; Polymerization; Inhibitor;
One step flow-through adsorptive purification of tubulin from tissue homogenate
Keywords: توبولین; CELBEADS; Protein purification; Tubulin;
Modifications des neurofilaments et des microtubules axonaux en fonction du mécanisme lésionnel : étude pathologique et expérimentale
Keywords: توبولین; Neurofilament; Neuropathie; Polyradiculonévrite démyélinisante inflammatoire chronique; Sclérose en plaques; Tubuline; Chronic inflammatory demyelinating neuropathy; Multiple sclerosis; Neurofilament; Tubulin;
MYND domain specific interaction of the melanin-concentrating hormone receptor 1 interacting zinc-finger protein with α- and β-tubulin
Keywords: توبولین; PDZ affinity purification; MIZIP; Tubulin; MYND;
Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo
Keywords: توبولین; MAP kinase; Neuron; Tubulin; Neurofilament; Microtubules; Protein; Central nervous system; Brain; Spinal cord; Sensory neuron; Sympathetic neuron; Vagus neuron; Dorsal root ganglia; Visceral nerve; Sensory ganglia; axon; Dendrite; Cervical ganglion; Adren
Trap RACK1 with Ras to mobilize Src signaling at syndecan-2/p120-GAP upon transformation with oncogenic ras
Keywords: توبولین; KB-Ras(Q61K); Src; Syndecan-2; p120-GAP; RACK1; Tubulin;
Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines
Keywords: توبولین; Indole-4,7-diones; Cytotoxic activity; Cell cycle specificity; Tubulin;
Identification of proteins binding the native tubulin dimer
Keywords: توبولین; Tubulin; Microtubules; Tubulin-associated proteins;
The effect of sub-lethal ALA-PDT on the cytoskeleton and adhesion of cultured human cancer cells
Keywords: توبولین; ALA; 5-aminolevulinic acid; CD; cytochalasin D; EDTA; ethylenediamine tetraacetate; FCS; foetal calf serum; PBS; phosphate buffered saline; PDT; photodynamic therapy; PpIX; protoporphyrin IX; TBS; phosphate buffered saline with milk powder and Triton X-10
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease
Keywords: توبولین; Quinone; Tubulin; Microtubule; Alzheimer's disease; Oxidative damage;
Mechanisms of 4-hydroxynonenal-induced neuronal microtubule dysfunction
Keywords: توبولین; Disorders of the Nervous System; Degenerative disease: Alzheimer's-miscellaneous; BSO; buthione sulfoximine; DEM; diethyl maleate; DMEM; Dulbecco's Modified Eagle Medium; EGTA; ethylenglycol-bis(2-aminoethylether)-N,N,Nâ³,Nâ²-tetraacetic acid; FBS; fe
Direct interaction between prion protein and tubulin
Keywords: توبولین; Prion protein; Tubulin; Microtubules; Cross-linking; Complexes;
Immunocytochemical localization of tubulins in spermatids and spermatozoa of Euptoieta hegesia (Lepidoptera: Nymphalidae)
Keywords: توبولین; Immunocytochemistry; Tubulin; Apyrene; Eupyrene; Lacinate appendages;
Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo
Keywords: توبولین; Bupleurum scorzonerifolium; Lung cancer; Apoptosis; Caspases; Cell cycle; Tubulin;
New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation
Keywords: توبولین; Tubulin; Combretastatin A4; Carboxamides; Carbamates