PUM1 promotes ovarian cancer proliferation, migration and invasion
Keywords: تومورزایی; PUM1; Ovarian cancer; Tumorigenesis; Progression;
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Transketolase like 1 (TKTL1) expression alterations in prostate cancer tumorigenesis
Keywords: تومورزایی; Prostate carcinoma; Transketolase like 1; Field cancerization; Metabolomics; Tumorigenesis; Biomarker;
Functions and mechanisms of microRNA-31 in human cancers
Keywords: تومورزایی; 3â²-UTRs3â²; -untranslated regions; ADC; Adenocarcinoma; BC; Breast cancer; BER; base excision repair; CDK4; cyclin-dependent kinase 4; CRC; Colorectal cancer; CRT; chemo-radiation therapy; C-TAD; COOH terminal transactivation domain; DHR1; dihydrorhoda
SIX1 reduces the expression of PTEN via activating PI3K/AKT signal to promote cell proliferation and tumorigenesis in osteosarcoma
Keywords: تومورزایی; SIX1; PTEN; PI3K/AKT; Tumorigenesis; Osteosarcoma;
The long noncoding RNA ZFAS1 facilitates bladder cancer tumorigenesis by sponging miR-329
Keywords: تومورزایی; ZFAS1; Bladder cancer; miR-329; Tumorigenesis;
Proliferating cell nuclear antigen promotes cell proliferation and tumorigenesis by up-regulating STAT3 in non-small cell lung cancer
Keywords: تومورزایی; PCNA; STAT3; Proliferation; Tumorigenesis; NSCLC;
COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells
Keywords: تومورزایی; Lung adenocarcinoma; COPB2; YAP1; Proliferation; Apoptosis; Tumorigenesis;
LncRNA-LINC00460 facilitates nasopharyngeal carcinoma tumorigenesis through sponging miR-149-5p to up-regulate IL6
Keywords: تومورزایی; lncRNAs; long noncoding RNAs; NPC; nasopharyngeal carcinoma; EMT; epithelial-to-mesenchymal transition; ceRNA; competing endogenous RNAs; miR-149-5p; hsa-miRNA-149-5p; ANOVA; one-way analysis of variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; I
STAT1-mediated upregulation of lncRNA LINC00174 functions a ceRNA for miR-1910-3p to facilitate colorectal carcinoma progression through regulation of TAZ
Keywords: تومورزایی; lncRNAs; long noncoding RNAs; CRC; colorectal carcinoma; EMT; epithelial-to-mesenchymal transition; ceRNA; competing endogenous RNAs; miR-1910-3p; hsa-miRNA-1910-3p; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IHC
Overexpressed ACBD3 has prognostic value in human breast cancer and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway
Keywords: تومورزایی; ACBD3; Acyl-CoA binding domain containing 3; ER; estrogen receptor; PR; progesterone receptor; Her2; human epidermal growth factor receptor-2; CSC; cancer stem cell; BCSC; breast cancer stem cell; EGFR; epidermal growth factor receptor; ACBP; acyl-CoA-bin
Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer
Keywords: تومورزایی; Eukaryotic elongation factor-2; eEF-2 kinase; Lung cancer; Liposomes; Rottlerin; siRNA; Signaling; Survival; Tumorigenesis;
MicroRNA-449a suppresses hepatocellular carcinoma cell growth via G1 phase arrest and the HGF/MET c-Met pathway
Keywords: تومورزایی; Hepatocellular carcinoma; miR-449a; c-Met; Proteomics; Tumorigenesis;
A new enzyme immunoassay for the determination of highly sialylated and fucosylated human α1-acid glycoprotein as a biomarker of tumorigenesis
Keywords: تومورزایی; AGP; α1-acid glycoprotein; AS-AGP; asialo-α1-acid glycoprotein; EIA; enzyme immunoassay; AAL; Aleuria aurantia lectin; Con A; concanavalin A; BSA; bovine serum albumin; PD-1; programmed death-1; Fuc; fucose; Gal; galactose; GlcNAc; N-acetylglucosamine;
Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis
Keywords: تومورزایی; Human oncogenic viruses; Cellular microRNAs; MicroRNA expression regulation; Tumorigenesis;
Re-evaluating the role of FOXOs in cancer
Keywords: تومورزایی; RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Low-folate stress reprograms cancer stem cell-like potentials and bioenergetics metabolism through activation of mTOR signaling pathway to promote in vitro invasion and in vivo tumorigenicity of lung cancers
Keywords: تومورزایی; Low folate; Lung cancer stem cell; Metabolic signaling; bioenergetics; Tumorigenesis;
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice
Keywords: تومورزایی; Oncogene; Pancreatic Cancer; Transcriptional Regulator; Tumorigenesis; 2D; 2-dimensional; 3D; 3-dimensional; ATP; adenosine triphosphate; IPMN; intraductal papillary mucinous neoplasm; MCN; mucinous cystic neoplasm; PI3K; phosphatidylinositol 3-kinase; Pa
14-3-3ζ promotes esophageal squamous cell carcinoma invasion by repressing S1PR2 protein expression through NF-κB signaling
Keywords: تومورزایی; ESCC; 14-3-3ζ; S1PR2; Tumorigenesis;
MicroRNA-30e-5p suppresses non-small cell lung cancer tumorigenesis by regulating USP22-mediated Sirt1/JAK/STAT3 signaling
Keywords: تومورزایی; Non-small cell lung cancer; MicroRNA-30e-5p; Ubiquitin-specific peptidase 22; Tumorigenesis; Tumor suppressor; Oncogene;
Ro60/SSA levels are increased and promote the progression of pancreatic ductal adenocarcinoma
Keywords: تومورزایی; Ro60/SSA; Autoantibody; Pancreatic ductal adenocarcinomacortactin; Tumorigenesis; Invasion;
Knockdown of ZNF233 suppresses hepatocellular carcinoma cell proliferation and tumorigenesis
Keywords: تومورزایی; ZNFs; zinc finger proteins; HCC; hepatocellular carcinoma; ZFNs; zinc finger factors; RNFs; ring finger proteins; PHF; PHD finger proteins; ESCs; embryonic stem cells; DMEM; Dulbecco's modified eagle's medium; MOI; multiplicity of infection; PI; propidium
LOX-1 receptor: A potential link in atherosclerosis and cancer
Keywords: تومورزایی; Lectin-like oxidized low-density lipoprotein receptor-1; Lectin-like receptor for oxidized low-density lipoproteins; Reactive oxygen species; Atherogenesis; Tumorigenesis; Angiogenesis;
DNA methylation patterns of the S100A14, POU2F3 and SFN genes in equine sarcoid tissues
Keywords: تومورزایی; Equine sarcoids; DNA methylation; SFN; S100A14; POU2F3; Tumorigenesis;
Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway
Keywords: تومورزایی; JPJD; Jianpi Jiedu decoction; CRC; colorectal cancer; TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labeling; IHC; immunohistochemistry; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; mTOR; mammalian target of rapamyc
Targeting heparanase to the mammary epithelium enhances mammary gland development and promotes tumor growth and metastasis
Keywords: تومورزایی; Heparanase; Mammary gland; Development; Signaling; Tumorigenesis;
Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2
Keywords: تومورزایی; lncRNAs; long noncoding RNAs; ceRNA; competing endogenous RNAs; miR-363-5p; hsa-miRNA-450b-5p; LINC00319; long intergenic non-protein coding RNA 319; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IHC; immunohistoche
ISG15 promotes esophageal squamous cell carcinoma tumorigenesis via c-MET/Fyn/β-catenin signaling pathway
Keywords: تومورزایی; ISG15; interferon-stimulated gene 15; ESCC; esophageal squamous cell carcinoma; c-MET; mesenchymal-epithelial transition factor; Esophageal squamous cell carcinoma; Interferon-stimulated gene 15; C-MET/Fyn/β-catenin pathway; Tumorigenesis;
MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression
Keywords: تومورزایی; Malignant melanoma; miR-143-3p; Cyclooxygenase-2 (COX-2); Inflammation; Tumorigenesis;
DA-Raf, a dominant-negative antagonist of the Ras-ERK pathway, is a putative tumor suppressor
Keywords: تومورزایی; Ras-ERK pathway; Raf; Alternative splicing; Transformation; Tumorigenesis; Tumor suppressor;
Long non-coding RNA FOXD2-AS1 aggravates nasopharyngeal carcinoma carcinogenesis by modulating miR-363-5p/S100A1 pathway
Keywords: تومورزایی; lncRNAs; long noncoding RNAs; NPC; nasopharyngeal carcinoma; EMT; epithelial-to-mesenchymal transition; ceRNA; competing endogenous RNAs; miR-363-5p; hsa-miRNA-363-5p; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; I
Wnt11 alters integrin and cadherin expression by ovarian cancer spheroids and inhibits tumorigenesis and metastasis
Keywords: تومورزایی; Epithelial ovarian cancer; Wnt11; Spheroids; Integrin; Cadherin; Tumorigenesis; Metastasis;
Jade family PHD finger 3 (JADE3) increases cancer stem cell-like properties and tumorigenicity in colon cancer
Keywords: تومورزایی; JADE3; Colon cancer; Cancer stem cells; Tumorigenesis; LGR5;
Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer
Keywords: تومورزایی; LRP8; Triple-negative breast cancer; Breast cancer stem cells; Tumorigenesis; Wnt/β-catenin signaling;
Mechanism of cancer: Oncohistones in action
Keywords: تومورزایی; Oncohistone; Histone modification; Tumorigenesis; Pediatric cancer;
Up-regulation of INSR/IGF1R by C-myc promotes TSCC tumorigenesis and metastasis through the NF-κB pathway
Keywords: تومورزایی; INSR, IGF1R; Tumorigenesis; Metastasis; NF-κB pathway; C-myc; Tongue squamous cell carcinoma;
Axed MUC4 (MUC4/X) aggravates pancreatic malignant phenotype by activating integrin-β1/FAK/ERK pathway
Keywords: تومورزایی; Pancreatic cancer; MUC4; MUC4/X; Splice isoform; Tumorigenesis; Metastasis;
Functional analysis of Cullin 3 E3 ligases in tumorigenesis
Keywords: تومورزایی; Cullin 3; Ubiquitin; SPOP; Keap1; Tumorigenesis; Mouse models;
The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells
Keywords: تومورزایی; Tumor suppressor gene; Tumorigenesis; microRNAs; miR-17-92 cluster;
Transplanting mouse induced pluripotent stem cells into mouse otocysts in vivo
Keywords: تومورزایی; Cell transplantation; iPS; Otocyst; Connexin 30; Tumorigenesis;
Regulatory mechanisms of long noncoding RNAs on gene expression in cancers
Keywords: تومورزایی; Long noncoding RNA; biological function; regulatory mechanism; gene expression; tumorigenesis;
Regulatory roles of brain-specific angiogenesis inhibitor 1(BAI1) protein in inflammation, tumorigenesis and phagocytosis: A brief review
Keywords: تومورزایی; Cancer; BAI; Tumorigenesis; Inflammation;
NSAID-activated gene 1 and its implications for mucosal integrity and intervention beyond NSAIDs
Keywords: تومورزایی; NAG-1; Mucosal inflammation; Tumorigenesis; Fibrogenesis;
Original ArticlesSMC1A recruits tumor-associated-fibroblasts (TAFs) and promotes colorectal cancer metastasis
Keywords: تومورزایی; SMC1A; Colorectal liver metastasis; Tumor-associated-fibroblasts; Tumorigenesis; Recruitment;
Data on the association of CMPK1 with clinicopathological features and biological effect in human epithelial ovarian cancer
Keywords: تومورزایی; TGF-β signaling; UMP/CMP kinase; Tissue microarray; Tumorigenesis; miRNA; Therapeutic target;
Long non-coding RNA PCAT7 regulates ELF2 signaling through inhibition of miR-134-5p in nasopharyngeal carcinoma
Keywords: تومورزایی; Prostate cancer associated transcript 7 (PCAT7); miR-134-5p; ELF2; Nasopharyngeal carcinoma (NPC); Tumorigenesis;
Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis via modulating antioxidants enzymes system in ICR mice
Keywords: تومورزایی; Annona muricata; Tumorigenesis; Antioxidant enzymes; Annonacin;
Elevated expression of KLK8 predicts poor prognosis in colorectal cancer
Keywords: تومورزایی; KLK8; Colorectal cancer; Tumorigenesis; Prognosis;
Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo
Keywords: تومورزایی; Pancreatic ductal adenocarcinoma (PDAC); ADAM17; Inhibitory antibody; Tumorigenesis; Targeted therapy;
Long non-coding RNA FTH1P3 facilitates oral squamous cell carcinoma progression by acting as a molecular sponge of miR-224-5p to modulate fizzled 5 expression
Keywords: تومورزایی; lncRNAs; long noncoding RNAs; OSCC; oral squamous cell carcinoma; EMT; epithelial-to-mesenchymal transition; FTH1P3; ferritin heavy chain 1 pseudogene 3; ceRNA; competing endogenous RNAs; miR-224-5p; hsa-miRNA-224-5p; ANOVA; One-Way Analysis of Variance;
Oncogenic signalling pathways in benign odontogenic cysts and tumours
Keywords: تومورزایی; Odontogenic tumours; Odontogenic cysts; Oral cancer; Tumorigenesis; Benign tumours; Oncogenic mutations; Oncogenic signalling; Genetics;