Keywords: فعال کننده پلاسمینوژن نوع urokinase; IFN; interferon; TMA; thrombotic microangiopathy; HUVECs; human umbilical vein endothelial cells; IFNAR; IFN-α/β receptor; JAKs; Janus kinases; STAT; signal transducer and activator of transcription; mAb; monoclonal antibody; VEGF; vascular endothelial
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Keywords: فعال کننده پلاسمینوژن نوع urokinase; Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
Keywords: فعال کننده پلاسمینوژن نوع urokinase; 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Nanomedicine; Nanodiagnostics; Liquid biopsy; Biophotonics; Pancreatic cancer detection; Pancreatic ductal adenocarcinoma; Sub-femtomolar limit of detection; AJCC; American Joint Commission on Cancer; MMP; matrix metalloproteinase; CTS; cathepsin; UpA; ur
Keywords: فعال کننده پلاسمینوژن نوع urokinase; A2Ms; α-2- macroglobulins; AFLEI; elastase inhibitor from Aspergillus flavus; AFUEI; elastase inhibitor from Aspergillus fumigatus; AP; α-2-antiplasmin; AT; antithrombin; bFGF; basic fibroblast growth factor; BSuPI; Bacillus subtilis protease inhibitor;
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ADAMs; a disintegrin and metalloproteinases; ADAMTS; ADAMs with thrombospondin motifs; Col; collagen; CS; chondroitin sulfate; CTGF; connective tissue growth factor; DS; dermatan sulfate; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epith
Keywords: فعال کننده پلاسمینوژن نوع urokinase; PAI-1; Urokinase-type plasminogen activator; Maintenance therapy; Ovarian cancer; Plasmin; Psammocarcinoma;
Biological properties of propolis extracts: Something new from an ancient product
Keywords: فعال کننده پلاسمینوژن نوع urokinase; DHT; 5α-dihydrotestosterone; ABCA1; ATP-binding cassette A1; AR; androgen receptor; cIAP-2; baculoviral IAP repeat-containing protein3; Bax; Bcl-2-associated X protein; CAPE; caffeic acid phenethyl ester; ERK; extracellular signal-regulated kinases; IL1-
Keywords: فعال کننده پلاسمینوژن نوع urokinase; BVs; blood vessels; CSF; cerebrospinal fluid; ECM; extracellular matrix; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; IF; immunofluorescence; LV; lateral ventricle; MRI; magnetic resonance imaging; PBS; phosphate
Keywords: فعال کننده پلاسمینوژن نوع urokinase; uPA; urokinase-type plasminogen activator; uPA16-244; serine protease domain of uPA (residues 16-244); KD; equilibrium dissociation constant; Ki; equilibrium inhibition constant; PAB; p-aminobenzamidine; Serine proteases; uPA; Enzyme catalysis; Cyclic
Keywords: فعال کننده پلاسمینوژن نوع urokinase; endogenous lysis; plasminogen activator inhibitor; streptokinase; synergy; tissue plasminogen activator; urokinase-type plasminogen activator; AMI; acute myocardial infarction; ICH; intracranial hemorrhage; PCI; percutaneous coronary intervention; pro-uPA
Keywords: فعال کننده پلاسمینوژن نوع urokinase; uPA; urokinase-type plasminogen activator; uPAR; uPA receptor, all forms; uPAR(I-III); intact uPAR; uPAR(I); uPAR domain I; uPAR(II-III); cleaved uPAR domains II-III; TR-FIA; time-resolved fluorescence immunoassay; CRC; colorectal cancer; CV; coeffi
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Peptide therapeutics; Intracellular PPI; Undruggable targets; Peptide drugs; Stapling; Hydrogen bond surrogates; Beta-hairpin mimetics; Molecular grafting; Macrocyclization; PPI; protein-protein interaction; HTS; high-throughput screening; PK; pharmacok
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ARNT; aryl hydrocarbon nuclear translocator; BCRP; breast cancer resistant protein; CAD; C-terminal activation domain; CAIX; carbonic anhydrase IX; CAV1; caveolin-1; ccRCC; clear cell renal cell carcinoma; CSC; cancer stem cells; DAG; diacylglycerol; DUSP
Keywords: فعال کننده پلاسمینوژن نوع urokinase; uPA; urokinase-type plasminogen activator; uPAR; urokinase-type plasminogen activator receptor; TR-FIA; time-resolved fluorescence immunoassays; OS; overall survival; PS; performance status; HR; hazard ratio; BID; bis in die = twice daily; Urokinase pla
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Peripheral arterial occlusive disease; Thrombolytic therapy; Endovascular procedures; Embolism and thrombosis; Hemorrhage; Urokinase-type plasminogen activator;
Keywords: فعال کننده پلاسمینوژن نوع urokinase; BC; bladder cancer; NMI; nonmuscle invasive; MMP; matrix metalloproteinase; uPA; urokinase-type plasminogen activator; NO; nitric oxide; iNOS; inducible nitric oxide synthase; nNOS; neuronal nitric oxide synthase; eNOS; endothelial nitric oxide synthase;
Keywords: فعال کننده پلاسمینوژن نوع urokinase; COX-2; cyclooxygenase-2; CTLs; Cytotoxic T Lymphocytes; DCs; dendritic cells; ECM; extracellular matrix; EGF; epidermal growth factor; FAK; focal adhesion kinase; FAP-α; fibroblast activation protein-α; FGF; fibroblast growth factor; HSCs; hepatic stell
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Stents; Prothesis related infections; Staphylococcal infections; Urokinase-type plasminogen activator; Endovascular procedures; False aneurysm;
Keywords: فعال کننده پلاسمینوژن نوع urokinase; APC; adenomatous polyposis coli; APE1/Ref; apurinic apyrimidinic endonuclease redox effector factor; APK; activated protein kinase; BTG; B-cell translocation gene; CSC; cancer stem cells; CSF; colony-stimulating factor; DSH; disheveled; ECGF1; endothelial
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Urokinase-type plasminogen activator; Soluble urokinase-type plasminogen activator receptor; Pelvic inflammatory disease; Polymorphism;
A novel solution phase PAI-1/uPA-biotin complex assay for the measurement of active PAI-1 in plasma
Keywords: فعال کننده پلاسمینوژن نوع urokinase; PAI-1; Plasminogen Activator Inhibitor 1; uPA; urokinase-type plasminogen activator; mAb; Monoclonal Antibody; pAb; Polyclonal Antibody; PE; Streptavidin-R-Phycoerythrin;
Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice
Keywords: فعال کننده پلاسمینوژن نوع urokinase; HCV; Glecaprevir; Pibrentasvir; Sofosbuvir; NS5A inhibitor resistance associated variant; P32 deletion; Human hepatocyte chimeric mouse; ASV; asunaprevir; DAAs; Direct-acting antivirals; DCV; daclatasvir; GLE; glecaprevir; HCV; hepatitis C virus; LDV; led
A label-free photoelectrochemical biosensor for urokinase-type plasminogen activator detection based on a g-C3N4/CdS nanocomposite
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Urokinase-type plasminogen activator; Biosensor; Photoelectrochemistry; C3N4/CdS;
Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection
Keywords: فعال کننده پلاسمینوژن نوع urokinase; SmVAL; Schistosoma mansoni venom allergen-like; SCP/TAPS; sperm coat protein/Tpx-1/Ag5/PR-1/Sc7; ECM; extracellular matrix; BM; basement membrane; PLG; plasminogen; uPA; urokinase-type plasminogen activator; Schistosomiasis; SCP/TAPS; SmVAL18; Plasminogen
Regulation and biological roles of the multifaceted miRNA-23b (MIR23B)
Keywords: فعال کننده پلاسمینوژن نوع urokinase; miRNAs; MicroRNAs; C9orf3; Chromosome 9 Open Reading Frame 3; pri-miRNAs; primary miRNA; pre-miRNAs; precursor miRNAs; miRISC; miRNA-induced silencing complex; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; ACTA2; smooth muscle α-actin; MYH
Improving the catalytic efficiency of Fibrinolytic enzyme from Serratia marcescens subsp. sakuensis by chemical modification
Keywords: فعال کننده پلاسمینوژن نوع urokinase; CAD; coronary artery disease; VTE; venous thromboembolism; tPA; tissue-type plasminogen activator; uPA; urokinase-type plasminogen activator; SK; streptokinase; DEPC; Diethylpyrocarbonate; DTNB; 5, 5-Dithio-bis-(2-nitrobenzoic) acid; EDAC; 1-Ethyl-3-(3-di
Integrin αvβ6: Structure, function and role in health and disease
Keywords: فعال کننده پلاسمینوژن نوع urokinase; DC; dendritic cells; EBV; Epstein-Barr virus; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; EMT; epithelial-to-mesenchymal transformation; ERK; extracellular signal-regulated kinase; FMDV; foot-and-mouth disease virus; HSV; herpes s
Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection
Keywords: فعال کننده پلاسمینوژن نوع urokinase; CAM; ER Stress Response; Assembly Inhibitor Core Protein; Replication; DAA; ALT; alanine aminotransferase; CAM; capsid assembly modulator; cccDNA; covalently closed circular DNA; ER; endoplasmatic reticulum; ETV; entecavir; h-Alb; human albumin; HAP; hete
Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators
Keywords: فعال کننده پلاسمینوژن نوع urokinase; BMP; bone morphogenetic protein; Cldn1; Claudin1; Co-Smad; common-partner Smad; CRC; colorectal cancer; DSS; dextran sodium sulfate; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; GALT; gut-associated lymphoid tissue; Id; inhibitor
Preclinical uPAR-targeted multimodal imaging of locoregional oral cancer
Keywords: فعال کننده پلاسمینوژن نوع urokinase; uPAR; urokinase-type plasminogen activator receptor; uPA; urokinase-type plasminogen activator; SPECT; single-photon emission computed tomography; PET; positron emission tomography; NIR; near infrared; FGS; fluorescent guided surgery; EGFR; epithelial gro
mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer
Keywords: فعال کننده پلاسمینوژن نوع urokinase; mTORC2; Urokinase-type plasminogen activator; uPAR; Akt; Cell migration;
Research ArticleHuman liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation
Keywords: فعال کننده پلاسمینوژن نوع urokinase; HEV; hepatitis E virus; uPA; urokinase-type plasminogen activator; SCID; severe combined immunodeficiency; PCR; polymerase chain reaction; ORF; open reading frame; UTR; untranslated region, USB, uPA/SCID/beige; i.v.; intravenous; GT; genotype; ELISA; enzy
A Bifunctional Approach of Immunostimulation and uPAR Inhibition Shows Potent Antitumor Activity in Melanoma
Keywords: فعال کننده پلاسمینوژن نوع urokinase; B-RAFi; B-RAF inhibition; ctrl; control; CXCL10; C-X-C motif chemokine 10; DR; acquired double resistance to B-RAFi and MEKi; MEKi; mitogen-activated protein kinase/extracellular signal-regulated kinase inhibition; OH; unmodified siRNA (hydroxy terminus);
Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib
Keywords: فعال کننده پلاسمینوژن نوع urokinase; CVD; cardiovascular disease; CHF; congestive heart failure; ctrl; control; DOX; doxycycline; ECM; Extracellular Matrix; LV; lentiviral; HFpEF; heart failure with preserved ejection function; Hgf; hepatocyte growth factor; HCM; hypertrophic cardiomyopathy;
Ecotin: Exploring a feasible antithrombotic profile
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Ecotin; Thrombin inhibitor; Factor Xa inhibitor; Ecotin-WT; ecotin wild type; ecotin-RR; ecotin with two mutations at the primary binding site; TF.FVIIa; tissue factor-factor VIIa; PT; prothrombin time; APTT; activated partial thromboplastin time; TT; t
Surface-displayed glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis enhance the activation of the fibrinolytic system of the host
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ES; excretory/secretory; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GAL; galectin; rDiGAPDH; recombinant form of the GAPDH of D. immitis; rDiGAL; recombinant form of the GAL of D. immitis; tPA; tissue plasminogen activator; uPA; urokinase-type plasm
Anti-metastatic effects of Rheum Palmatum L. extract in human MDA-MB-231 breast cancer cells
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Rheum palmatum L.; Invasion, Matrix metalloproteinases; Urokinase-type plasminogen activator; Nuclear factor-κB; MDA-MB-231
Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR
Keywords: فعال کننده پلاسمینوژن نوع urokinase; mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo
Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9-Mediated Cytokine Release From Myeloid Cells
Keywords: فعال کننده پلاسمینوژن نوع urokinase; IBD; Mouse Model; Plasminogen; UC; Ab; antibody; CXCL5; C-X-C motif chemokine ligand 5; DAI; disease activity index; DSS; dextran sulfate sodium; FDP; fibrin degradation product; IBD; inflammatory bowel disease; IL; interleukin; MMP; matrix metalloprotein
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ABTS; 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); AML; acute myeloid leukemia; ApnA; diadenosine polyphosphates; ATP; adenosine-5â²-triphosphate; ATX; autotaxin; BALF; bronchoalveolar lavage fluid; bis-pNPP; bis(p-nitrophenyl) phosphate; BLM
A novel polymorphism in the PAI-1 gene promoter enhances gene expression. A novel pro-thrombotic risk factor?
Keywords: فعال کننده پلاسمینوژن نوع urokinase; PAI-1; plasminogen activator inhibitor-1; SERPIN; serine protease inhibitors; t-PA; tissue-type plasminogen activator; u-PA; urokinase-type plasminogen activator; USF-1; upstream stimulatory factor-1; ATIII; antithrombin III; HPA-1; human platelet antigen
The PLAU P141L Single Nucleotide Polymorphism Is Associated With Collateral Circulation in Patients With Coronary Artery Disease
Keywords: فعال کننده پلاسمینوژن نوع urokinase; CAD; coronary artery disease; CCC; coronary collateral circulation; DM; diabetes mellitus; SNP; single nucleotide polymorphism; u-PA; urokinase-type plasminogen activator; Plasminogen activator; rs2227564 polymorphism; Collateral circulation; Association
Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ECM; extracellular matrix; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor (EGFR); FACS; fluorescence-activated cell sorting; FBS; fetal bovine serum; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; IR; ionizi
Human DExD/H RNA helicases: Emerging roles in stress survival regulation
Keywords: فعال کننده پلاسمینوژن نوع urokinase; 5â²ppp; 5â² triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint
Lung-Derived Factors Mediate Breast Cancer Cell Migration through CD44 Receptor-Ligand Interactions in a Novel Ex Vivo System for Analysis of Organ-Specific Soluble Proteins
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ALDH; aldehyde dehydrogenase; ANOVA; analysis of variance; AP; alkaline phosphatase; bFGF; basic fibroblast growth factor; BM; bone marrow; BMSC; bone marrow stromal cell; BrdU; bromodeoxyuridine; CD; cluster of differentiation; CM; conditioned media; COX
Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin
Keywords: فعال کننده پلاسمینوژن نوع urokinase; Colorectal cancer; Cancer-associated fibroblasts; Migration; Claudin-11; SILAC; CAF; cancer-associated fibroblast; CALD; caldesmon; CLN11; claudin 11; CM; conditioned media; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; ICC; immuno
Do-it-yourself histidine-tagged bovine enterokinase: A handy member of the protein engineer's toolbox
Keywords: فعال کننده پلاسمینوژن نوع urokinase; BENAC; benzamidine affinity chromatography; EK; enterokinase; GST; glutathione-S-transferase; IB; inclusion body; IEC; ion exchange chromatography; IMAC; mmobilized metal ion affinity chromatography; KLK; kallikrein-related peptidase; SUMO; small ubiquiti
A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections
Keywords: فعال کننده پلاسمینوژن نوع urokinase; ALT; alanine aminotransferase; GCV; ganciclovir; HBV; hepatitis B virus; HCV; hepatitis C virus; HSA; human serum albumin; HSVtk; herpes simplex virus type-1 thymidine kinase; IFN; interferon; PegIFN-alpha; pegylated interferon-alpha; RI; repopulation ind
Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells
Keywords: فعال کننده پلاسمینوژن نوع urokinase; PEITC; phenethyl isothiocyanate; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulphate; HIF-1α; hypoxia-inducible factor-1; VEGF; vascular endothelial growth factor; uPA; urokinase-type plasminogen activat