Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; NC, noncollagenous; COL, collagenous; MMP, matrix metalloproteinase; bFGF, basic fibroblast growth factor; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; SPARC, secreted protein acidic and rich in cysteine; T
مقالات ISI VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی (ترجمه نشده)
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Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; cAMP, cyclic AMP; PDE3, type III phosphodiesterase; eNOS, endothelial nitric oxide synthese; PKA, protein kinase A; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; LEC, lymphatic endothelial cells; kCYC+/−, k-
Proangiogenic factors in the development of HCC in alcoholic cirrhosis
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; ALD, alcoholic liver disease; HIF, hypoxia-induced factor; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; HCC, hepatocellular carcinoma; NLD, non-liver disease; pVHL, Von Hippel-Lindau protein; HIFs, hypoxia-
Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; NO, nitric oxide; NOS, nitric oxide synthase; VEGF, Vascular endothelial growth factor; VEGFR, Vascular endothelial growth factor receptor; RCC, clear cell carcioma; TKI, tyrosine kinase inhibitorsTyrosine kinase inhibitors; Hypertension; Vascular endothe
Oral adverse events in cancer patients treated with VEGFR-directed multitargeted tyrosine kinase inhibitors
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; TKI, tyrosine kinase inhibitors; VEGFR, vascular endothelial growth factor receptor; EGFR, epidermal growth factor receptor; HER2, human epidermal growth factor receptor 2; PDGFR, platelet-derived growth factor receptor; VR-TKI, VEGFR-directed multitarget
VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; GBM, glioblastoma; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; TGFβ, transforming growth factor beta; TGFβR, transforming growth factor beta receptor; HGF, hepatocyte growth factor; MET, mesenchymal epithe
Anti-vascular endothelial growth factor receptor (VEGFR) 2 autoantibody identification in glioblastoma patient using single B cell-based antibody gene cloning
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RT-PCR, reverse transcription-polymerase chain reaction; PBMC, peripheral blood mononuclear cell; ELISA, enzyme-linked immunosorbent assay; VEGFR, vascular endothelial growth factor receptor; SPR, surface plasmon resonanceSingle B cell; Human IgG ELISA; H
VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGFR, vascular endothelial growth factor receptor; NRP, neuropilin; ORS, outer root sheath; IRS, inner root sheath; DP, hair follicle dermal papilla; DPC, hair follicle dermal papilla cell; DAPI, 4,6-diamidino-2-phenylindole; Jun, jun oncogene; ERK, extr
Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; ABC, ATP-binding cassette; ABCB1, ABC transporter-subfamily B member 1; ABCG2, ABC transporter-subfamily G member 2; MDR, multidrug resistance; VEGFR, vascular endothelial growth factor receptor; TKI, tyrosine kinase inhibitorABC transporter; ABCG2; Multi
Design, synthesis, and biological evaluation of novel FAK scaffold inhibitors targeting the FAK–VEGFR3 protein–protein interaction
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; Focal adhesion kinase; Vascular endothelial growth factor receptor-3; Protein–protein interaction; Focal adhesion targeting domain; FAK scaffold inhibitorFAK, focal adhesion kinase; VEGFR, vascular endothelial growth factor receptor; FERM, 4.1 protein–ezr
Interleukin-8 as a modulator of response to bevacizumab in preclinical models of head and neck squamous cell carcinoma
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; HNSCC, head and neck squamous cell carcinoma; IL-8, interleukin-8; IL-1α, interleukin-1α; VEGF, vascular endothelial growth factor; FGF-a, fibroblast growth factor-a; TNF-α, tumor necrosis factor-α; VEGFR, vascular endothelial growth factor receptor; EGFR
N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: Design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastati
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RTK, receptor tyrosine kinase; EGFR, epithelial growth factor receptor; VEGFR, vascular endothelial growth factor receptor; PDGFR, platelate derived growth factor receptor; CAM, chorioallantoic membrane; Abl, abelson tyrosine kinase; CML, chronic myelogen
Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; MAPK, Ras-mitogen activated protein kinase; VEGFR, vascular endothelial growth factor receptor; CSFR1, colony stimulating factor-1 receptor; RTK’s, receptor tyrosine kinases; STK’s, serine threonine kinases; TK, tyrosine kinases; KDR, kinase domain recept
The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; HNE, 4-hydroxy-2-nonenal; GST, glutathione S-transferase; LPO, lipid peroxidation; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; HUVEC, human umbilical vascular endothelial cells; RPE, retinal pigment epithe
Vascular endothelial growth factor-D is a key molecule that enhances lymphatic metastasis of soft tissue sarcomas
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; HLEC, human lymphatic endothelial cells; PDGF, platelet-derived growth factor; FGF, fibroblast growth factor-basic; ANG-1, angiopoietin-1; PGI, phosphoglucose is
RhoB mediates antitumor synergy of combined ixabepilone and sunitinib in human ovarian serous cancer
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; STR, short tandem repeat; EOC, epithelial ovarian cancer; GOG, Gynecologic Oncology Group; PDGFR, Platelet-derived growth factor receptor; VEGFR, Vascular endothelial growth factor receptor; TKI, Tyrosine kinase inhibitorOvarian cancer; Receptor-tyrosine
N-glycans in cell survival and death: Cross-talk between glycosyltransferases
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; Dol-P, dolichylmonophosphate; GPT, N-acetylglucosaminyl 1-phosphste transferase; DPMS, mannosylphospho dolichol synthase; Dol-P-Man, mannosylphospho dolichol; Gl
Biomarkers predicting tumor response and evasion to anti-angiogenic therapy
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; DBP, diastolic blood pressure; PFS, progression-free survival; OS, overall survival; VEGF, vascular endothelial growth factor; PIGF, Placental growth factor; VEGFR, vascular endothelial growth factor receptor; sVEGFR, soluble vascular endothelial growth f
Design and synthesis of 5,6-fused heterocyclic amides as Raf kinase inhibitors
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; MAPK, ras-mitogen activated protein kinase; VEGFR, vascular endothelial growth factor receptor; PDGFR, platelet-derived growth factor receptor; CSF-1, colony stimulating factor-1 receptor; RTK’s, receptor tyrosine kinases; STK’s, serine threonine kinases;
Vascular endothelial growth factor-A gene polymorphisms in women with recurrent pregnancy loss
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RPL, recurrent pregnancy loss; VEGFA, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; SNP, single nucleotide polymorphism; NCBI, national center for biotechnology information; 5′UTR, 5′ untranslated region; 3′UTR, 3
The angiogenic process as a therapeutic target in cancer
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; FGF2, fibroblast growth factor 2; HGF, hepatocyte growth factor; PDGF, platelet derived endothelial growth factor; PIGF, placental growth factor; Dll4, delta lik
The VD1 Neutralizing Antibody to Vascular Endothelial Growth Factor-D: Binding Epitope and Relationship to Receptor Binding
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF-D; structure/function; cancer; therapeutics; mutagenesisVEGF-D, vascular endothelial growth factor-D; VEGFR, vascular endothelial growth factor receptor; VHD, VEGF homology domain; PlGF, placenta growth factor; LAM, lymphangioleiomyomatosis; mAb, mon
The contribution of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity in 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RTK, receptor tyrosine kinase; EGF, epidermal growth factor receptor; VEGF, vascular endothelial growth factor; PDGF, platelet derived growth factor; EGFR, epidermal growth factor receptor; VEGFR, vascular endothelial growth factor receptor; PDGFR, platel
Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis—A possible target for novel therapies?
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; CsA, cyclosporin AVEGF; Inflammation; Skin; Psoriasis; Angiogenesis
Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography–electrospray ionization-tandem mass spectrometry and pharmacokinetic application
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MRM, multiple reaction monitoring; LOQ, limit of quantification; ESI, electrospray ionization; VEGFR, vascular endothelial growth factor receptor; PDGFR, platelet-derived growth factor receptor; c-
Why do Kinase Inhibitors Cause Cardiotoxicity and What can be Done About It?
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; TK, tyrosine kinase; KI, kinase inhibitors; TKI, tyrosine kinase inhibitors; CML, chronic myeloid leukemia; GIST, gastrointestinal stromal tumors; LV, left ventricle; AMPK, AMP-activated protein kinase; VEGFR, vascular endothelial growth factor receptor;
Synthesis and biological activity of N4-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RTK, receptor tyrosine kinase; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor receptor; VEGFR, vascular endothelial growth factor receptor; IGF-1, insulin-like growth factor-1; Flt-3, fms-like tyrosine kinase 3; c-Kit, stem
Dermatologic symptoms associated with the multikinase inhibitor sorafenib
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; bid, twice daily; CK, cytokeratin; HFSR, hand–foot skin reaction; TARGETs, Treatment Approaches in Renal cancer Global Evaluation Trial; VEGFR, vascular endothelial growth factor receptor
Challenges in cancer research and multifaceted approaches for cancer biomarker quest
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; MAP, mitogen-activated protein; PI3K, phosphatidylinositol-3 kinase; mTOR, mammalian target of rapamycin; Prom1, Prominin 1; EGFRs, epidermal growth factor receptors; VEGFR, vascular endothelial growth factor receptor; PDGFRs, platelet-derived growth fact
Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; RTK, receptor tyrosine kinase; VEGFR, vascular endothelial growth factor receptor; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor receptor; FGFR, fibroblast growth factor receptor; ATP, adenosine 5′-triphosphate; DHFR, dihyd
Circulating Progenitor Cells Can Be Reliably Identified on the Basis of Aldehyde Dehydrogenase Activity
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; ALDH, aldehyde dehydrogenase; ALDHbr, aldehyde dehydrogenase-bright; CAD, coronary artery disease; EPC, endogenous progenitor cell; FACS, fluorescence-activated cell sorting; MNC, mononuclear cell; VEGFR, vascular endothelial growth factor receptor
Hypoxia/Notch signaling in primary culture of rat lymphatic endothelial cells
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; rLECs, rat lymphatic endothelial cells; rVECs, rat vascular endothelial cells; VEGFR, vascular endothelial growth factor receptor; NRP, neuropilin; HIF, hypoxia-inducible factor; Dll, delta-like ligand; GSI, γ-secretase inhibitor; DDN, a dominant negative
VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; GEF, guanine nucleotide exchange factor; GAP, GTPase activating protein; HUVECs, human umbilical vein endothelial cells; HMVEC-d, human microvascular endothelial
Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; angiogenesis; vascular endothelial growth factor-B; X-ray crystallography; receptor-binding; cysteine-knot proteinVEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; PlGF, placenta growth factor; r.m.s., root-mean
Pericytes from human non-small cell lung carcinomas: An attractive target for anti-angiogenic therapy
Keywords: VEGFR، گیرنده فاکتور رشد اندوتلیال عروقی; EC, endothelial cells; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; HMVEC, human microvascular endothelial cells; HDF, human dermal fibroblast; bFGF, basic fibroblast growth factor; MSC, mesenchymal stem ce