کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3286394 | 1209294 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Proangiogenic factors in the development of HCC in alcoholic cirrhosis
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Proangiogenic factors in the development of HCC in alcoholic cirrhosis Proangiogenic factors in the development of HCC in alcoholic cirrhosis](/preview/png/3286394.png)
چکیده انگلیسی
SummaryAlcoholic liver disease, the most common cause of liver cirrhosis, is associated with an increased risk for hepatocellular carcinoma. Angiogenic factors have been implicated in pathophysiology of cirrhosis, and of hepatocellular carcinoma, and in particular of alcoholic liver cirrhosis, due to alcohol induced hypoxia associated with increased hepatic oxygen consumption. In one study, it was found that among genetic polymorphisms in proangiogenic factors, KDR and VEFGA may confer an increased risk of HCC, in patients with ALD. There is need of further studies of the proangiogenic factors in HCC, in order to help us define their use as prognostic markers and also as markers of response to treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 39, Supplement 1, September 2015, Pages S104–S108
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 39, Supplement 1, September 2015, Pages S104–S108
نویسندگان
Mariana V. Machado, Helena Cortez-Pinto,