Keywords: IFN; interferon; TMA; thrombotic microangiopathy; HUVECs; human umbilical vein endothelial cells; IFNAR; IFN-α/β receptor; JAKs; Janus kinases; STAT; signal transducer and activator of transcription; mAb; monoclonal antibody; VEGF; vascular endothelial
مقالات ISI (ترجمه نشده)
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Keywords: Proliferative diabetic retinopathy; TXNIP; Angiogenesis; VEGFR2; Akt/mTOR;
Keywords: 4HNE; 4-Hydroxy-2-nonenal; AC; Adenylyl cyclase; AD; Alzheimer's disease; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; cAMP; Cyclic adenosine 3â²,5â²-monophosphate; CB; Cannabinoid receptor; CHO; Chinese hamster ovary; DAL; Dehydro-
Keywords: CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; ALI; air-liquid interface; α-SMA; alpha-smooth muscle actin; ATII; alveolar type II cells; ATS; American Thoracic Society; AFM; atomic force microscopy; COPD; Chronic Obstructive Pulmonary
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; α-SMA; alpha- smooth muscle actin; BBB; blood-brain barrier; BDNF; brain derived neurotrophic factor; bFGF or FGF2; basic fibroblast growth factor; BrdU; bromodeoxyuridine; CIMT; const
Keywords: Angiogenesis; Endometriosis; VEGFR2; VEGF; Polymorphisms;
Keywords: Gastric cancer; Esophagogastric junction cancer; Gastroesophageal adenocarcinoma; HER2; VEGFR2; EGFR; MET; FGFR2;
Keywords: vWF; von Willebrand factor; STEMI; ST elevation myocardial infarction; CAD; coronary artery disease; VEC; vascular endothelial cell; LEC; lymphatic endothelial cell; Endothelial cell; Surface marker; CD34; CD31; VEGF; VEGFR2;
Keywords: VEGF; vascular endothelial growth factor; VEGFR1; vascular endothelial growth factor receptor type 1; VEGFR2; vascular endothelial growth factor receptor type 2; VEGFR3; vascular endothelial growth factor receptor type 3;
Keywords: Vascular smooth muscle cell; Embryonic stem cells; Induced pluripotent stem cells; Lateral plate mesoderm; Neural crest; Serum-free; Coronary; VSMCs; vascular smooth muscle cells; VEGF; vascular endothelial growth factor; PAH; pulmonary arterial hypertens
Keywords: Infantile hemangioma; Semaphorin; Plexin; MAPK; Facultative stem cell; Endothelial cell; SEMA3; class 3 semaphorin; SEMA3E&F; semaphorin 3E and 3F; IH; infantile hemangioma; HemSC; hemangioma stem cells; GLUT1; glucose transporter 1; EC; endothelial cell;
Keywords: EPOR; erythropoietin receptor; HIF; hypoxia-inducible factors; IGF-1; insulin growth factor-1; IGFBP3; insulin-like growth factor binding protein 3; IVNV; intravitreal neovascularization; JAK; Janus-activated kinase; OIR; oxygen-induced retinopathy; PRVD;
Keywords: VEGF; vascular endothelial growth factor; TGF-β; transforming growth factor-β; ECM; extracellular matrix; EC; endothelial cell; SPARC; secreted protein acidic and rich in cysteine; PG; proteoglycan; GAG; glycosaminoglycan; SLRP; small leucine-rich prote
Keywords: Contrast-enhanced ultrasound; Molecular ultrasound; Quantitative imaging; Multiple injections; Cancer; SonoVue; Vascular endothelial growth factor receptor 2; VEGFR2; Reproducibility; Peak enhancement; Time to peak;
Keywords: Angiogenesis; Placenta; Pre-eclampsia; VEGFR2; PhosphorylationVEGF, vascular endothelial growth factor; VEGFR2, vascular endothelial growth factor receptor type 2; Y951, tyrosine 951; Y1175, tyrosine 1175; LOPE, late-onset pre-eclampsia; EOPE, early-onset
Keywords: GA; Psoriasis; K14-VEGF transgenic mice; Angiogenesis; VEGFR2; CD3
Keywords: VEGF; vascular endothelial growth factor; VEGFR2; VEGF receptor 2; Nrp; Neuropilin; PlGF; placenta growth factor; PLCγ; phospholipase Cγ; VE-cadherin; vascular endothelial cadherin; TSAd; T-cell-specific adapter; HSPGs; heparan sulfate proteoglycans; Hs
DMH4, a VEGFR2 inhibitor, effectively suppresses growth and invasion of lung cancer cells
Keywords: DMH4; Lung cancer; Antiangiogenic; Small molecules; VEGF; VEGFR2;
Circulating CD34+ and CD34+VEGFR2+ progenitor cells are associated with KLOTHO KL-VS polymorphism
Keywords: ARMS-PCR; amplification refractory mutation system-polymerase chain reaction; eGFR; estimated glomerular filtration rate; eNOS; endothelial nitric oxide synthase; EPCs; endothelial progenitor cells; FGFRs; fibroblast growth factor receptors; MnSOD; ma
Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival
Keywords: Survivin; VEGFR2; AKT1; MDM2; Esophageal cancer;
Antitumor activity of BJ-1207, a 6-amino-2,4,5-trimethylpyridin-3-ol derivative, in human lung cancer
Keywords: Aminopyridin-3-ols; Non-small cell lung cancer; NADPH oxidase; Stem cell factor; Transforming growth factor-α; Akt; protein kinase B; CAM; chick chorioallantoic membrane; c-KIT; cellular homolog of the feline sarcoma viral oncogene v-kit; DPPH; 1,1-diphe
Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications
Keywords: Mouse embryonic stem cells; Endoderm hepatic specification; Endothelial cells; VEGFR2; Epigenetic modifications; ESC; human embryonic stem cell; EB; embryoid body; AL End; mouse ESC-derived endoderm cells cultured alone; CC End; mouse ESC-derived endoderm
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
PBA2 exhibits potent anti-tumor activity via suppression of VEGFR2 mediated-cell proliferation and angiogenesis
Keywords: Angiogenesis; Anti-tumor activity; Multi-tyrosine kinases inhibitor; PBA2; VEGFR2;
Endogenous acetylcholine regulates neuronal and astrocytic vascular endothelial growth factor expression levels via different acetylcholine receptor mechanisms
Keywords: Vascular endothelial growth factor; Endogenous acetylcholine; Acetylcholine receptor; Medial septal cholinergic neurons; ACh; acetylcholine; AChE; acetylcholinesterase; AChR; acetylcholine receptor; AraC; cytosine β-d-arabinofuranoside hydrochloride; CCh
Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway
Keywords: Antrodia cinnamomea; Anti-angiogenic activity; Endothelial cells; VEGFR2; STAT3;
Novel thioureido-benzenesulfonamide derivatives with enaminone linker as potent anticancer, radiosensitizers and VEGFR2 inhibitors
Keywords: Benzenesulfonamides; HEPG2; VEGFR2;
CS2164 exerts an antitumor effect against human Non-Hodgkin's lymphomas in vitro and in vivo
Keywords: Non-Hodgkin's lymphomas (NHLs); CS2164; VEGFR2; Aurora B;
LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo
Keywords: HUVECs; human umbilical vein endothelial cells; CAM; chicken chorioallantoic membrane; VEGFR; vascular endothelial growth factor receptor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; DMSO; dimethyl sulfoxide; LW-215
Epithelium-derived miR-204 inhibits corneal neovascularization
Keywords: MicroRNA-204; Corneal epithelium; Neovascularization; VEGF; VEGFR2; Biomechanical stress;
Blockade of vascular endothelial growth factor receptor-1 (Flt-1), reveals a novel analgesic for osteoarthritis-induced joint pain
Keywords: OA; osteoarthritis; PMM; partial medial meniscectomy; h; hour; PWT; paw withdrawal threshold; PTT; paw thermal threshold; DRG; dorsal root ganglion; IT; intrathecal; IA; intraarticular; RT-PCR; Real-time polymerase chain reaction; P; probability; SEM; sta
Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties
Keywords: Crocus sativus; Natural food coloring; Phytomedicine; Cancer; SCLC; small-cell lung cancer; NSCLC; non-small-cell lung cancer; BCS; breast-conserving surgery; VEGFR2; vascular endothelial growth factor receptor; CNS; central nervous system; NMSCs; non-mel
Anlotinib inhibits angiogenesis via suppressing the activation of VEGFR2, PDGFRβ and FGFR1
Keywords: VEGF; vascular endothelial growth factor; FGF-2; fibroblast grow factor 2; PDGF-BB; platelet-derived growth factor-BB; VEGFR2; VEGF receptor 2; FGFR1; FGF receptor 1; PDGFRβ; PDGF receptor β; TKI; tyrosine kinase inhibitor; DMSO; dimethylsulfoxide; BSA;
Mapping Txnip: Key connexions in progression of diabetic nephropathy
Keywords: ARRB; arrestin beta; ARRDC; arrestin domain containing protein; ASK-1; apoptosis signal-regulating kinase-1; Cys; cysteine; ECM; extracellular matrix; FOXO; forkhead box protein; Gly; glycine; IL-1β; interleukin-1 β; JNK; c-Jun-N-terminal kinase; MAPK;
PAC-1 and its derivative WF-210 Inhibit Angiogenesis by inhibiting VEGF/VEGFR pathway
Keywords: PAC-1; WF-210; Procaspase-3 activator; Anti-angiogenesis; VEGFR2;
Shengui Sansheng San extraction is an angiogenic switch via regulations of AKT/mTOR, ERK1/2 and Notch1 signal pathways after ischemic stroke
Keywords: Angiogenesis; Homeostasis; Ischemic stroke; Shengui Sansheng San; BMCs; bone marrow-derived cells; BMECs; brain microvascular endothelial cells; CBF; cerebral blood flow; DMEM; Dulbecco's modified eagle's medium; ECs; endothelial cells; EPCs; endothelial
Dual targeting c-met and VEGFR2 in osteoblasts suppresses growth and osteolysis of prostate cancer bone metastasis
Keywords: Prostate cancer; Bone metastasis; Osteoblasts; c-Met; VEGFR2;
Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway
Keywords: VEGFR1; VEGFR2; Peptide design; Angiogenesis; Tumor growth;
Necl-4 enhances the PLCγ-c-Raf-MEK-ERK pathway without affecting internalization of VEGFR2
Keywords: Endocytosis; Endothelial cells; Signaling; VEGF; VEGFR2; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; ERK; extracellular signal-regulated kinase; HUVECs; human umbilical vein endothelial cells; MEK; mitogen-activated protein kinase/ERK kinase; m
Enhanced effect of VEGF165 on L-type calcium currents in guinea-pig cardiac ventricular myocytes
Keywords: VEGF; vascular endothelial growth factor; LTCC; L-type calcium channel; VEGFR2; VEGF type-2 receptor; ICa,L; L-type calcium currents; AP; action potential; APD; action potential duration; EC coupling; excitation-contraction coupling; IV; current-voltage;
Heterogeneity of circulating tumor cells (CTCs) in patients with recurrent small cell lung cancer (SCLC) treated with pazopanib
Keywords: TTF-1; CD56; VEGFR2; Immunofluorescence; CellSearch; SCLC; CTCs; Pazopanib;
Silica nanoparticles inhibit macrophage activity and angiogenesis via VEGFR2-mediated MAPK signaling pathway in zebrafish embryos
Keywords: Silica nanoparticles; Macrophage activity; Angiogenesis; VEGFR2; MAPK singaling pathway; Zebrafish;
The binding of the bone morphogenetic protein antagonist gremlin to kidney heparan sulfate: Such binding is not essential for BMP antagonism
Keywords: BMP; bone morphogenetic protein; CAN; Cerberus and DAN; CKD; chronic kidney disease; DAN; differentially screening selected gene abberative in neuroblastoma; FGF; fibroblast growth factor; GAG; glycosaminoglycan; HS; heparan sulfate; MGR; mutant gremlin;
FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation
Keywords: FGD5; FYVE, RhoGEF and PH domain containing 5; Cdc42; cell division cycle 42; VEGFA; vascular endothelial growth factor A; VEGFR2; vascular endothelial growth factor receptor 2; HMVEC; human microvascular endothelial cells; GEF; guanine nucleotide exchang
miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells
Keywords: KLF2; Kruppel Like Factor 2; HUVEC; human umbilical vascular endothelial cells; miRNA; microRNA; TP; target protectors; VEGFA; vascular endothelial growth factor A; VEGFR2; vascular endothelial growth factor A receptor 2; KDR; kinase insert domain recepto
CAR T-cell therapy for lung cancer and malignant pleural mesothelioma
Keywords: ACT; adoptive cell therapy; ADC; adenocarcinoma; ALK; anaplastic lymphoma kinase; CAF; cancer-associated fibroblast; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DNR; dominant negative
Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
Keywords: Cediranib (Pubchem CIC 9933475); Pazopanib (Pubchem CIC 10113978); Vandetanib (Pubchem CIC 3081361); Sorafenib (Pubchem CIC 216239); Furimazine (Pubchem CIC 219083); VEGF; VEGFR2; BRET; Ligand binding; Receptor tyrosine kinase inhibitors;
The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis
Keywords: MMRN2; Multimerin 2; EC; endothelial cell; ECM; extracellular matrix; FGF-2; fibroblast growth factor 2; VEGFA; vascular endothelial growth factor A; VEGFR2; vascular endothelial growth factor receptor 2; MMP; matrix metalloproteinase; MOI; multiplicity o
Targeting GPNMB with glembatumumab vedotin: Current developments and future opportunities for the treatment of cancer
Keywords: AE; Adverse Event; α-MSH; alpha-Melanocyte Stimulating Hormone; ADC; Antibody-Drug Conjugate; ASPS; Alveolar Soft Part Sarcoma; ASPSCR1; Alveolar Soft Part Sarcoma Chromosome Region Candidate 1; BMP-2; Bone Morphogenetic Protein-2; BRK; Breast Tumor Kina
ITE Suppresses Angiogenic Responses in Human Artery and Vein Endothelial Cells: Differential Roles of AhR
Keywords: AhR; Aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; CYP1A1; cytochrome P450 family 1 member A1; CYP1B1; cytochrome P450 family 1 member B1; BM; basal RPMI 1640 media; CGM; complete growth medium; FBS; fetal bovine serum; FGF2; fibroblast growth factor