Keywords: Ciona intestinalis; Botryllus schlosseri; Pregnane X receptor; Saccharomyces cerevisiae; Marine biotoxins; Bioassay; AD; activation domain; AF-2; transcription activation function domain; BsVDR/PXRα; Botryllus schlosseri VDR/PXR orthologue α; BPA; bisph
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Steroids from Helleborus caucasicus reduce cancer cell viability inducing apoptosis and GRP78 down-regulation
Keywords: Helleborus caucasicus; Ecdysteroids; Bufadienolides; Cell viability; Apoptosis; GRP78; DMSO; dimethylsulfoxide; MTT; 3-(4,5 dimethylthiazol-2-yl)-2,5diphenyltetrazolium; BrdU; bromodeoxyuridine; DEVD; Asp-Glu-Val-Asp; pNA; p-nitroanilide; VP16; Etoposide;
The canonical Wnt/β-catenin signaling pathway stimulates herpes simplex virus 1 productive infection
Keywords: HSV-1; Productive infection; β-catenin dependent transcription; β -catenin inhibitor (iCRT14); VP16;
Hyperactivated Stat3 boosts axon regeneration in the CNS
Keywords: VP16; Activation domain; Transcription factor; Optic nerve; Neurite outgrowth; Axon regeneration;
CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism
Keywords: HSV-1; CD40 ligand; PIK3K; VP16; Autophagy; Atg5;
Which polymer is more suitable for etoposide: A comparison between two kinds of drug loaded polymeric micelles in vitro and in vivo?
Keywords: Micelle; MPEG-PDLLA; MPEG-PCL; VP16;
VP16 fusion induces the multiple-knockout phenotype of redundant transcriptional repressors partly by Med25-independent mechanisms in Arabidopsis
Keywords: VP16; Transcriptional repressor; Dominant activation; Mediator25 (Med25); Arabidopsis; FLOWERING LOCUS C (FLC);
DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal
Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit
Telomere dysfunction induced by chemotherapeutic agents and radiation in normal human cells
Keywords: β2-M; β2-microglubin; ConA; concanavalin A; DOX; doxorubicin; DSB; double strand DNA break; hTERC; human telomerase RNA component; hTERT; human telomerase reverse transcriptase; IF; immunofluorescence; qRT-PCR; quantitative RT-PCR; TIF; telomere dysfunc
Functional dissection of the Hox protein Abdominal-B in Drosophila cell culture
Keywords: Hox protein; Abdominal-B; Transcriptional activation; Cut; VP16;
NMR structure of the human Mediator MED25 ACID domain
Keywords: TAD; Transcriptional activation domain; MED; Mediator; ACID; Activator interacting domain; PTOV; Prostate tumour overexpressed; SPOC; Spen paralog and ortholog C-terminal; NMR; Mediator; MED25; PTOV; VP16; Transcriptional activation domain;
Interaction of the N-terminus of ecdysone receptor isoforms with the ligand-binding domain
Keywords: Aa; amino acid; AF; activation function; AR; androgen receptor; CFP; cyan fluorescent protein; DBD; DNA binding domain; EcR; ecdysone receptor; EcRE; ecdysone response element; ER; estrogen receptor; FRET; fluorescence resonance-energy transfer; LBD; liga
Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpoints
Keywords: Bcl; B cell leukemia/lymphoma protein; Bcl-xL; Bcl-2-related gene x, long isoform; BH; Bcl-2 homology domain; CDC; cell division cycle; CDK; cyclin dependent kinase; CLIP170; cytoplasmic linker protein 170; HA; influenza hemagglutinin epitope tag; PCR; po
Chromatin assembly on herpes simplex virus genomes during lytic infection
Keywords: Herpes simplex virus; HSV-1; Chromatin-modifying coactivator; Histone acetyltransferase; Chromatin remodeling enzyme; VP16; Histone; Nucleosome; Lytic infection; Latent infection
Virion incorporation of the herpes simplex virus type 1 tegument protein VP22 is facilitated by trans-Golgi network localization and is independent of interaction with glycoprotein E
Keywords: HSV-1; Virus assembly; VP22; Acidic cluster; gE; VP16; Virion Incorporation;
One-step affinity purification of recombinant TATA binding proteins utilizing a modular protein interaction partner
Keywords: TBP; Transcription factor; Promoter; VP16; TAF1; TAND2; TBP-associated factor; Transcriptional activation domain
Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity
Keywords: Curcumin; Chromatin; Coactivator; Transcriptional activation; Lytic infection; VP16
The HSV-1 tegument protein pUL46 associates with cellular membranes and viral capsids
Keywords: HSV-1; pUL46; VP16; VP22; UL37; UL11; VP5; Tegument; Membrane association; Envelopment
The Arabidopsis AtbZIP9 protein fused to the VP16 transcriptional activation domain alters leaf and vascular development
Keywords: Arabidopsis thaliana; AtbZIP9 transcription factor; VP16; Vascular cylinder development; Phloem;
Incorporation of the herpes simplex virus type 1 tegument protein VP22 into the virus particle is independent of interaction with VP16
Keywords: HSV-1; VP22; UL49; VP16; UL48; Virion incorporation; Dileucine motif; Tegument; Tegumentation; Membrane association
Effects of different zinc finger transcription factors on genomic targets
Keywords: Polydactyl zinc finger; Artificial transcription factor; Genomic target site; Linker design; DNA binding; In vivo regulation; Yeast (Saccharomyces cerevisiae); MEL1; VP16; Mig1p
Herpes simplex virus regulatory proteins VP16 and ICP0 counteract an innate intranuclear barrier to viral gene expression
Keywords: Herpes simplex virus; VP16; ICP0; Innate immunity; Somatic cell hybrid; Cell fusion; Reovirus p14
Enhanced long-term expression from helper virus-free HSV-1 vectors packaged in the presence of deletions in genes that modulate the function of VP16, UL46 and UL47
Keywords: Long-term expression; VP16; UL46; UL47; Neurofilament promoter; Herpes simplex virus vector; Gene transfer; Gene therapy;
Tight transcriptional regulation of foreign genes in insect cells using an ecdysone receptor-based inducible system
Keywords: Ecdysone receptor; Inducible expression; Stably transformed insect cells; Baculovirus; VP16;
An activation domain within the walleye dermal sarcoma virus retroviral cyclin protein is essential for inhibition of the viral promoter
Keywords: WDSV; rv-cyclin; cdk8; Cyclin C; Sur2; TBP; VP16; Mediator;
In vitro transdifferentiation of hepatoma cells into functional pancreatic cells
Keywords: Pancreas; Liver; Transdifferentiation; Pdx-1; XlHbox8; Endocrine; Exocrine; Nuclear translocation; VP16; GLP-1; Betacellulin;