دانلود مقالات ISI درباره Xpa + ترجمه فارسی

Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue

Keywords: PARP-1; poly (ADP-ribose) polymerase 1; NER; Nucleotide excision repair; BER; base excision repair; HEKn; Normal neonatal human epidermal keratinocytes; XPA; xeroderma pigmentosum group A; UVR; ultraviolet radiation; (6-4)PP; 6,4-photoproduct; CPD; cyclob

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cytotoxic platinum coordination compounds. DNA binding agents

Keywords: 1,0,1/t,c,t; [{trans-PtCl(NH3)2}2μ-cis-Pt(NH3)2{H2N(CH2)6NH2}2]4+; 1,0,1/t,t,t; trans-PtCl(NH3)2}2μ-trans-Pt(NH3)2{H2N(CH2)6NH2}2]4+ (BBR3464); 1,1/c,c; [{cis-PtCl(NH3)2}2µ-{H2N(CH2)6NH2}]2+; 1,1/c,c,prz; [{cis-Pt(NH3)2}2(µ-OH)(µ-pyrazolato)]2+; 1,1/

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2017 سفارش ترجمه

Kinetics and thermodynamics of zinc(II) and arsenic(III) binding to XPA and PARP-1 zinc finger peptides

Keywords: Arsenic(III); Zinc(II); XPA; PARP-1; Kinetics; Thermodynamics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular mechanisms of DNA damage recognition for mammalian nucleotide excision repair

Keywords: 6-4PP; Pyrimidine (6-4) pyrimidone photoproduct; BHD; β-Hairpin domain; CAK; CDK-activating kinase; CPD; Cyclobutane pyrimidine dimer; CUL4; Cullin 4; HD; RecA-like helicase domain; NER; Nucleotide excision repair; RBX1; RING-box protein 1; TFIIH; Transc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Role of the XPA protein in the NER pathway: A perspective on the function of structural disorder in macromolecular assembly

Keywords: Structurally disordered protein domains; Nucleotide Excision Repair (XPA); NER pre-incision complex; Beads-on-a-string multiprotein complex; XPA; RPA; ERCC1-XPF; Conformational selection; Molecular recognition

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy

Keywords: DNA repair; ERCC1; XPA; In silico modeling; Drug discovery; Cancer

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

XPA: A key scaffold for human nucleotide excision repair

Keywords: NER; nucleotide excision repair; XP; Xeroderma pigmentosum; TFIIH; transcription factor II H; RPA; replication protein A; WT; wild type; FL; full-length; AAF; N-(deoxyguanosin-8-yl)-2-acetylaminofluorene; (6-4)PP; (6-4)photoproduct; CPD; cyclobutane pyrim

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Xeroderma Pigmentosum Group A Promotes Autophagy to Facilitate Cisplatin Resistance in Melanoma Cells through the Activation of PARP1

Keywords: DPQ; 3,4-dihydro-5-[4-(1-piperidinyl) butoxy]-1(2H)-isoquinolinone; HMGB1; high-mobility group protein B1; LC3; light chain 3 protein; MC; normal human melanocytes; mTOR; mechanistic target of rapamycin; NER; nucleotide excision repair; PAR; poly(adenosin

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

High-resolution genomic assays provide insight into the division of labor between TLS and HDR in mammalian replication of damaged DNA

Keywords: BER; base excision repair; BP-G; benzo[a]pyrene-guanine adduct; CPD; cyclobutane pyrimidine dimer; CRISPR; clustered regularly-interspaced short palindromic repeats; CSTR; complementary strand transfer repair; DDT; DNA damage tolerance; DSB; double strand

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

NDR1 modulates the UV-induced DNA-damage checkpoint and nucleotide excision repair

Keywords: Nucleotide excision repair; NDR1; XPA; ATR; UV;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Interactive effects of ultraviolet-B radiation and pesticide exposure on DNA photo-adduct accumulation and expression of DNA damage and repair genes in Xenopus laevis embryos

Keywords: Amphibians; Climate change; HR23B; Insecticides; XPA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

Keywords: ApG; adenine-guanine; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3 related kinase; Bax; Bcl2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; EdU; 5-ethynyl-2′-deoxyuridine; CarboPt; carboplatin; CENP-F; centromere protein F; Chk1; checkpoint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Association of two ERCC4 tagSNPs with susceptibility to atrophic gastritis and gastric cancer in Chinese

Keywords: AG; atrophic gastritis; CHB; Chinese Han Beijing; CI; confidence interval; ELISA; enzyme-linked immunosorbent assay; H. pylori; Helicobacter pylori; HWE; Hardy-Weinberg Equilibrium; IgG; immunoglobin G; ERCC4/XPF; excision repair cross-complementing gro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Adduct formation and repair, and translesion DNA synthesis across the adducts in human cells exposed to 3-nitrobenzanthrone

Keywords: 3-NBA; 3-nitrobenzanthrone; ABA; aminobenzanthrone; dA-N6-C2-ABA; 2-(2′-deoxyadenosin-N6-yl)-3-aminobenzanthrone; dG-C8-N-ABA; N-(2′-deoxyguanosin-8-yl)-3-aminobenzanthrone; dG-N2-C2-ABA; 2-(2′-deoxyguanosin-N2-yl)-3-aminobenzanthrone; MRM; multiple

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear PtII complex

Keywords: AMPZ; [{cis-{Pt(NH3)2}2(μ-OH)(μ-pyrazolate)]2+; cisplatin; [cis-diamminedichloridoplatinum(II)]; bp; base pair; CL; cross-link; CT; calf thymus; DSC; differential scanning calorimetry; EMSA; electrophoretic mobility shift assay; FAAS; flameless atomic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions

Keywords: Doxorubicin; DNA polymerase eta (pol eta); XPV; XPA; LY294002; DNA repair;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk

Keywords: XPA; ERCC2; Polymorphisms; Lung cancer; Meta-analysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The xeroderma pigmentosum pathway: Decision tree analysis of DNA quality

Keywords: DDB1; DDB2; ERCC1; RPA; TFIIH; UV-DDB; XPA; XPB; XPC; XPD; XPE; XPF; XPG

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

17α-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells

Keywords: Ethinylestradiol; Zebrafish; Nucleotide excision repair; XPA; XPC; ICI 182,780

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach

Keywords: Virtual screening; Clustering; NCI dtp database; DrugBank; UCN01; XPA; ERCC1; Pharmacophore

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene

Keywords: RNA interference; shRNA; XPA; UV

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

DNA repair gets physical: Mapping an XPA-binding site on ERCC1

Keywords: DNA repair; Nucleotide excision repair; ERCC1; XPA; NMR; X-ray crystallography; Structure–function

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Polymorphisms in nucleotide excision repair genes, smoking and intake of fruit and vegetables in relation to lung cancer

Keywords: XPC; XPA; XPD; Lung cancer; Polymorphisms; Population-based

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Subchronic inhalation of mixtures of cigarette smoke constituents in Xpa−/−p53+/− knock-out mice: A comparison of intermittent with semi-continuous exposure to acetaldehyde, formaldehyde, and acrolein

Keywords: ANOVA; analysis of variance; B[a]P; benzo[a]pyrene; SC; semi-continuous exposure to a mixture of acetaldehyde, formaldehyde and acrolein; IE; intermittent exposure to a mixture of acetaldehyde, formaldehyde and acrolein; KO; knock-out; MV; mean tidal volu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Moving toward individualized therapy based on NER polymorphisms that predict platinum sensitivity in ovarian cancer patients

Keywords: Ovarian cancer; NER polymorphisms; XP genes; XPA; XPC; XPD exon10; XPD exon23; XPG; Platinum sensitivity; Platinum resistance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Genome instability and DNA damage accumulation in gene-targeted mice

Keywords: DNA repair; knockout; mouse; spontaneous DNA damage; ABH; AlkB homolog; AP; apurimidinic; BER; base excision repair; bp; base pair; cyPu; 5′,8-purine cyclodeoxynucleoside; DR; direct reversal; DSB; double-strand break; E. coli; Escherichia coli; ERCC1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages

Keywords: Nucleotide excision repair; XPC-HR23B; XPA; RPA; Photoaffinity modification

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells

Keywords: Ultraviolet radiation; Nucleotide excision repair; XPA; Protein; Inducible system

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: Role of ERCC1 in homologous recombination repair

Keywords: SiRNA, small interfering RNA; MMC, mitomycin C; ICL, interstrand crosslink; HRR, homologous recombinational repairSiRNA; XPA; ERCC1; Cisplatin; Mitomycin C; DNA repair

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Severe growth retardation and short life span of double-mutant mice lacking Xpa and exon 15 of Xpg

Keywords: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); XPA; XPG; Double-mutant mice;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

XP-A cells complemented with Arg228Gln and Val234Leu polymorphic XPA alleles repair BPDE-induced DNA damage better than cells complemented with the wild type allele

Keywords: XPA; Polymorphism; Benzo[a]pyrene-diol-epoxide; DNA repair; Poly(ADP-ribose);

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The yeast rDNA locus: A model system to study DNA repair in chromatin

Keywords: CHO; Chinese hamster ovary; CPDs; cyclobutane pyrimidine dimers; CS; Cockayne syndrome; CSB; CS group B; DAHC; histone deacetylases; FACT; facilitates chromatin transcription; GGR; global genomic repair; HAT; histone acetyltransferases; ISWI; imitation sw

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه