Keywords: α2-Adrenoceptor; Beam walking; Cannabinoid 1 receptor antagonist; Composite neuroscore; Epileptogenesis; Lateral fluid-percussion; Memory; Seizure susceptibility; Somato-motor performance; SR141716A;
مقالات ISI (ترجمه نشده)
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Keywords: Painful diabetic neuropathy (PDN); db/db Mice; α2-Adrenoceptor; Dexmedetomidine (DEX); Extracellular signal-regulated kinase (ERK);
Keywords: Agmatine sulfate salt (PubChem CID: 2794990); AGN 192403 hydrochloride (PubChem CID: 11957452); B-HT 933 dihydrochloride (PubChem CID: 169743); BU224 hydrochloride (PubChem CID: 11957470); desipramine hydrochloride (PubChem CID: 65327); gallamine triethio
Keywords: phentolamine (CID 5775); idazoxan (CID 54459); diazoxide (CID 58 3019); UK14 304 (CID 2435); Imidazoline; Phentolamine; Idazoxan; α2-adrenoceptor; KATP channel;
Keywords: Scorpion venom; Acini; Pancreatitis; Clonidine; Kidney; Glycemia; ANS; autonomic nervous system; α2-AR; α2-adrenoceptor; BUN; Blood urea nitrogen; GFR; glomerular filtration rate; Td; Tityus discrepans; WBC; white blood cells;
Presynaptic α2-adrenoceptor modulates glutamatergic synaptic transmission in rat nucleus accumbens in vitro
Keywords: α2-Adrenoceptor; Nucleus accumbens shell; Glutamatergic transmission; Excitatory postsynaptic current; Presynaptic modulation;
Differentially expressed genes in response to amitraz treatment suggests a proposed model of resistance to amitraz in R. decoloratus ticks
Keywords: Rhipicephalus decoloratus; Amitraz; Resistance; RNA-sequencing; α2-adrenoceptor; NMDA receptor; Calcium signalling;
Renal and femoral venous blood flows are regulated by different mechanisms dependent on α-adrenergic receptor subtypes and nitric oxide in anesthetized rats
Keywords: Nitric oxide; α2-Adrenoceptor; Blood flow; Vascular resistance; Venous tone;
Noradrenergic modulation of evoked dopamine release and pH shift in the mouse dorsal hippocampus and ventral striatum
Keywords: α2-AR; α2-adrenoceptor; ANOVA; analysis of variance; cf; carbon fiber; DiI; diaminobenzidine; DA; dopamine; DSP-4; N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine; FSCV; fast-scan cyclic voltammetry; NE; norepinephrine; NET; norepinephrine transporter; MFB
Dexmedetomidine alleviates rat post-ischemia induced allodynia through GRK2 upregulation in superior cervical ganglia
Keywords: G protein-coupled receptor kinase 2; Complex regional pain syndrome type I; Mechanical and cold allodynia; Superior cervical ganglion neurons; Dexmedetomidine; α2-Adrenoceptor;
Modulation of l-DOPA's antiparkinsonian and dyskinetic effects by α2-noradrenergic receptors within the locus coeruleus
Keywords: Locus coeruleus; l-DOPA-Induced dyskinesia; Norepinephrine; Clonidine; Atipamezole; α2-adrenoceptor;
Noradrenergic influences in the basolateral amygdala on inhibitory avoidance memory are mediated by an action on α2-adrenoceptors
Keywords: Norepinephrine; Basolateral amygdala; Retrodialysis; Memory modulation; Inhibitory avoidance learning; α2-Adrenoceptor;
Development of inhibitors of heterotrimeric Gαi subunits
Keywords: YCHJFGIMRPORGB-OAHLLOKOSA-O; YQOVLZRFLVGMEZ-LICLKQGHSA-O; HYXLQTFYNGEXFJ-MAEUFBSDSA-O; LHGBTBSCHLXDSE-UHFFFAOYSA-N; YXYGLLDQUHCHCW-GFCCVEGCSA-N; GQKIKSLNJUJCRR-BLLLJJGKSA-N; GIIQMSUODJUKJL-JSGCOSHPSA-N; OXSJZMCFMMRNHH-CPNJWEJPSA-N; NGFXXIKLZLDQGL-UHFFFAOY
Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities
Keywords: Marsanidine; Indazole; α2-Adrenoceptor; Selectfluor;
Research ReportXylazine induced central antinociception mediated by endogenous opioids and μ-opioid receptor, but not δ-or κ-opioid receptors
Keywords: Xylazine; Endogenous opioid; Central antinociception; α2-adrenoceptor;
Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat
Keywords: α1A-adrenoceptor; α1D-adrenoceptor; α2-adrenoceptor; α2A-adrenoceptor; Pithed rat; Vasopressor responses;
Characterization of α2B-adrenoceptor ligand binding in the presence of Muscarinic toxin α and delineation of structural features of receptor binding selectivity
Keywords: α2-Adrenoceptor; Chimeric receptor; Extracellular loop; Ligand binding; Mamba snake; Muscarinic toxin;
Blockade of α2-adrenoceptors induces Arc gene expression in rat brain in a glutamate receptor-dependent manner: A combined qPCR, in situ hybridisation and immunocytochemistry study
Keywords: Noradrenaline; α2-Adrenoceptor; Arc; Glutamate; AMPA; NMDA; mGluR;
Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain
Keywords: Clonidine; Neuropathic pain; Glial activation; Mirror image pain; α2-Adrenoceptor;
Chromaffin cell transplant in spinal cord reduces secondary allodynia induced by formalin in the rat. Role of opioid receptors and α2-adrenoceptors
Keywords: Chromaffin cell; Secondary allodynia; Opioid receptor; α2-Adrenoceptor; Spinal cord; Chronic pain;
α2-Adrenoceptor regulates the spontaneous and the GABA/glutamate modulated firing activity of the rat medial prefrontal cortex pyramidal neurons
Keywords: α2-adrenoceptor; medial prefrontal cortex; pyramidal neuron; microiontophoresis; extracellular recording; ADHD; attention-deficit/hyperactivity disorder; cAMP; cyclic AMP; CLO; clonidine hydrochloride; Glu; glutamate; HCN; hyperpolarization-activated cyc
Determination of α2-adrenoceptor and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by agmatine and BMS182874
Keywords: Agmatine; Endothelin ETA receptor; Morphine; Oxycodone; α2-Adrenoceptor; Imidazoline receptor; Idazoxan; Yohimbine; Naloxone; Antinociception;
α2-Adrenoceptor Functionality in Postmortem Frontal Cortex of Depressed Suicide Victims
Keywords: adenylyl cyclase; α2-adrenoceptor; cAMP; depression; G-protein; human brain;
From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease
Keywords: Ropinirole; Pramipexole; Pergolide; Antiparkinson; α2-Adrenoceptor; D2 receptor; D3 receptor; ACh; acetylcholine; Akt; atypical kinase; AR; adrenoceptor; BDNF; brain derived neurotrophic factor; COMT; catechol-Ortho-methyltransferase; DA; dopamine; ERK;
α2-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the l-arginine/nitric oxide/cyclic GMP pathway in rat
Keywords: Xylazine; α2-Adrenoceptor; Nitric oxide; Cyclic GMP; Peripheral antinociception;
Comparative study of α2-adrenoceptors in Fischer 344 and Lewis rats. Evidence for clonidine-induced place aversion
Keywords: Aversion; Clonidine; α2-adrenoceptor; Fischer; Lewis;
Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: Towards a mechanism underlying upregulations described in MCI patients?
Keywords: DSP-4; α2-adrenoceptor; 5-HT1B receptor; Substance P interneuron; Alzheimer's disease; Acetylcholine;
Effects of chronic desipramine treatment on α2-adrenoceptors and μ-opioid receptors in the guinea pig cortex and hippocampus
Keywords: Chronic desipramine treatment; α2-adrenoceptor; μ-opioid receptor; Hippocampus; Cortex; (Guinea pig);
Antinociceptive interactions of triple and quadruple combinations of endogenous ligands at the spinal level
Keywords: ADE; adenosine; AGM; agmatine; AUC; area under the curve; DRG; dorsal root ganglion; EM; endomorphin-1; FW; formula weight; KYNA; kynurenic acid; NMDA; N-methyl-d-aspartate; N-Ach; nicotinic acetylcholine; PLC; phospholipase C; TRPV1; transient receptor p
Presynaptic modulation of 5-HT release in the rat septal region
Keywords: lateral septum; medial septum; diagonal band; 5-HT1B; α2-adrenoceptor; opioid receptors; ACh; acetylcholine; ANOVA; analysis of variance; CGP-56,999A; 3-([1-(R)-(3-carboxyphenyl)ethylamino]2-(S)-hydroxy-propyl)-cyclohexyl-methyl-phosphinic acid (lithium
Pharmacological characterization and autoradiographic distribution of α2-adrenoceptor antagonist [3H]RX 821002 binding sites in the chicken brain
Keywords: chicken brain; α2-adrenoceptor; RX 821002; membrane homogenate binding; autoradiography; competition; ARC 239; 2-(2-4-(O-methoxyphenyl)-piperazin-1-yl)-ethyl-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione; Bmax; maximal number of binding sites; BRL 44408; 2-(
Locomotor hyperactivity induced by blockade of prefrontal cortical α2-adrenoceptors in monkeys
Keywords: Locomotor hyperactivity; α2-adrenoceptor; prefrontal cortex; monkey;
Lack of interaction between orexinergic and α2-adrenergic neuronal systems in rat cerebrocortical slices
Keywords: Orexin; α2-Adrenoceptor; OX1 antagonist; Norepinephrine; Cerebrocortex;
Effect of BU98008, an imidazoline1-binding site ligand, on body temperature in mice
Keywords: Imidazoline1-binding site; α2-Adrenoceptor; Body temperature;
Oxytocin increases the density of high affinity α2-adrenoceptors within the hypothalamus, the amygdala and the nucleus of the solitary tract in ovariectomized rats
Keywords: Neurotransmitters, modulators, transporters and receptors; Catecholamine receptors; Oxytocin; α2-adrenoceptor; Amygdala; Hypothalamus; Nucleus of the solitary tract;
Antinociception: Mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component
Keywords: α2-Adrenoceptor; 5-HT3 receptor; MD-354 (m-chlorophenylguanidine); Antinociception; In vivo model;
Gut-derived norepinephrine plays an important role in up-regulating IL-1β and IL-10
Keywords: Catecholamine; Small intestine; IL-1β; IL-10; IL-6; α2-Adrenoceptor; Yohimbine; Kupffer cell;
α2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: The role of nitric oxide and endogenous opioids
Keywords: Cholestasis; Mesenteric vascular bed; α2-Adrenoceptor; Clonidine; Nitric oxide; Opioid;
Synergy between intrathecal Ï-conotoxin CVID and dexmedetomidine to attenuate mechanical hypersensitivity in the rat
Keywords: α2-adrenoceptor; Ï-conotoxin CVID; Dexmedetomidine; Mechanical hypersensitivity; N-type Ca2+ channel;
Rat clonidine mydriasis model: imidazoline receptors are not involved
Keywords: Mydriasis; Rat; α2-Adrenoceptor; Imidazoline receptor; Clonidine; Rilmenidine;
Ultrasonic vocalization production of preweanling rats: Effects of central and peripheral administration of α2-adrenoceptor agonists
Keywords: Ultrasonic vocalization; α2-adrenoceptor; Clonidine; ST-91 (2-[2,6-diethylphenylamino]-2-imidazole);
α2-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons
Keywords: Firing activity; Antidepressant; 5-HT receptor; Idazoxan; Noradrenaline; α2-Adrenoceptor;
Behavioural, neural and cardiovascular adaptations in mice lacking the NPY Y1 receptor
Keywords: Neuropeptide Y; Stress; Novelty seeking; Open-field; Social defeat; Sympathetic and parasympathetic activity; Heart rate variability; Brainstem; α2-adrenoceptor; Cardiac fibrosis; Mice;