دانلود مقالات ISI درباره Β-Site App Cleaving Enzyme 1 + ترجمه فارسی

ترکیبات چندتایی که مویرهای ساختاری و عملکردی تاکرین و دونپزیل را دارند، برای درمان بالقوه بیماری آلزایمر

Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease

Keywords: ACh; acetylcholine; ChEs; cholinesterases; AChE; acetylcholinesterase; EeAChE; AChE from Electrophorus electricus; hAChE; human acetylcholinesterase; BuChE; butyrylcholinesterase; eqBuChE; BChE from equine serum; ChEI; ChE inhibitor; AChEI; AChE inhibitor

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

بیماری آلزایمر به علت از دست دادن عملکرد: یک سنتز جدید از داده های موجود

Alzheimer's disease due to loss of function: A new synthesis of the available data

Keywords: Aβ; β-Amyloid peptide; Aβ40; 40-amino acid isoform of β-Amyloid peptide; Aβ42; 42-amino acid isoform of β-Amyloid peptide; Aβ42/Aβ40; ratio of measured steady-state levels of Aβ42 and Aβ40; AD; Alzheimer's Disease; AICD; APP intracellular domain

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ1-42

Keywords: AD; Alzheimer's disease; Aβ; beta-amyloid; APC; antigen-presenting cell; BACE1; β-site APP cleaving enzyme 1; BBB; blood-brain barrier; CCK; cell-counting kit; CD40; cluster of differentiation 40; CNS; central nervous system; DAPI; 4′,6-diamidino-

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer's disease

Keywords: AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; Aβ; amyloid β peptides; ApoE; apolipoprotein E; APP; amyloid precursor proteins; BACE1; β-site APP cleaving enzyme 1; BIN1; bridging integrator 1; CBP; CREB-binding protei

دانلود رایگان متن کامل مقاله ISI 146 صفحه سال انتشار : 2018 سفارش ترجمه

siRNA delivery using polyelectrolyte-gold nanoassemblies in neuronal cells for BACE1 gene silencing

Keywords: AD; Alzheimer's disease; BACE1; β-site APP cleaving enzyme 1; LbL; Layer-by-layer; PAH-Cit; Citraconic anhydride modified poly (allylamine) hydrochloride; PE-Gold NAs; Polyelectrolyte-gold nanoassemblies; PEI; Polyethyleneimine; PLA; Poly l-arginine; siR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

Keywords: 4-PBA; 4-phenyl butyric acid; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid beta; AD; Alzheimer's disease; ATF3; activating transcription factor 3; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BACE1; β-site APP cleaving enz

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitoylation in Alzheimerâ¿¿s disease and other neurodegenerative diseases

Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer⿿s disease; ADAM17; a disintegrin and metalloproteinase 17; AICD; APP intracellular domain; AKAP79; A-kinase anchoring protein 79; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APP; amy

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2016 سفارش ترجمه

Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity

Keywords: AD; Alzheimer disease; FAD; familial AD; Aβ; amyloid-β peptide; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; PDMP; dl-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMAPP; (1S,2R-d-erythro-2-N-myristoylamino)-1-phenyl-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

RanBP9 overexpression reduces dendritic arbor and spine density

Keywords: AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; BCA; Bicinchoninic acid; BDNF; Brain-derived neurotrophic factor; DRG; dorsal root ganglion; F-actin; filamentous-actin; HD; Hunt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Lysophosphatidic acid induces increased BACE1 expression and Aβ formation

Keywords: AD; Alzheimer's disease; NFT; neurofibrillary tangles; Aβ; β amyloid; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; oxLDL; oxidized low-density lipoprotein; CSF; cerebrospinal fluid; LPA; lysophosphatidic acid; CREB; cAMP respons

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

BACE1 in Alzheimer's disease

Keywords: Aβ; β-amyloid; ACDL; acid-cluster dileucine motif; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease domain protein; AICD; amyloid precursor protein intracellular domain; APLP; amyloid precursor-like protein; ApoE; apolipoprotein E; APP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه