Keywords: Glucocorticoids; Opioid receptors; Pituitary-adrenal system; Psychological stress; Regulatory T lymphocytes; ACC; anterior cingulate cortex; β2AR; β2-adrenergic receptor; ACTH; adrenocorticotropic hormone; ADCYAP1R1; adenylate cyclase-activating polypep
مقالات ISI (ترجمه نشده)
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Keywords: Cx43; connexin43; FGF23; fibroblast growth factor 23; PTH; parathyroid hormone; BMD; bone mineral density; RANKL; receptor activator of nuclear factor kappa-B ligand; HSPC; hematopoietic stem/progenitor cell; G-CSF; granulocyte colony-stimulating factor;
Keywords: MD; molecular dynamics; CG; coarse-grained; NMR; nuclear magnetic resonance; ESR; electron spin resonance; EM; electron microscopy; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPG; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol; POPE; 1-pa
Keywords: ASM; airway smooth muscle; AHR; airway hyperresponsiveness; β2AR; beta 2 adrenergic receptor; BTR; bitter taste receptor; CysLT1R; cysteinyl leukotriene receptor 1; CaSR; calcium sensing receptor; EP; prostanoid EP receptor; GPCR; G protein-coupled recep
Keywords: β2AR; beta 2 adrenergic receptor; GR; glucocorticoid receptor; IFNGR; interferon-γ receptor; IL4R; interleukin-4 receptor; PBMC; peripheral blood mononuclear cells; PSS; Perceived Stress Scale; SNP; single nucleotide polymorphism; Cytokine receptor; Imm
Keywords: Air pollution; mechanisms; innate immunity; adaptive immunity; epigenetic regulation; AHR; Airway hyperreactivity; β2AR; β2-Adrenergic receptor; BC; Black carbon; CCCEH; Columbia Center for Children's Environmental Health; DAMP; Damage-associated molecu
Keywords: Glucocorticoid receptor; glucocorticoid; isoforms; glucocorticoid signaling; ACTH; Adrenocorticotropic hormone; AF; Activation function; AP1; Activator protein 1; β2AR; β2-Adrenergic receptor; CBG; Corticosteroid-binding globulin; DBD; DNA-binding domai
G protein-coupled receptor kinases: Past, present and future
Keywords: αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic
Novel mechanisms of G-protein-coupled receptors functions: AT1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk
Keywords: GPCR; angiotensin II; receptor cross-talk; bias; dimerization; α2CAR; α2C adrenergic receptor; AngII; angiotensin II; AT1R; AT1 angiotensin receptor; β2AR; β2-adrenergic receptor; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled recepto
Dissecting the signaling features of the multi-protein complex GPCR/β-arrestin/ERK1/2
Keywords: GPCRs; G protein-coupled receptors; TM; transmembrane; ECLs; extracellular loops; ICLs; intracellular loops; GRKs; G protein-coupled receptor kinases; MAPKs; mitogen activated protein kinases; ERK1/2; extracellular signal-regulated kinases 1 and 2; JNK; c
Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment
Keywords: A2AAR; adenosine receptor A2A; AUC; area under curve; β2AR; beta 2 adrenergic receptor; D3R; dopamine receptor D3; δOR; delta-opioid receptor; ECL; extracellular loop; GPCR; G protein-coupled receptor; H1R; histamine receptor H1; ICL; intracellular loop
Age-related regulation of bone formation by the sympathetic cannabinoid CB1 receptor
Keywords: eCBs; endocannabinoids; AEA; arachidonoyl ethanolamide; 2-AG; 2-arachidonoylglycerol; CB1; cannabinoid-1; CB2; cannabinoid-2; β2AR; β2 adrenergic receptors; NE; norepinephrine; CNS; central nervous system; DBH; dopamine-β-hydroxylase; BV/TV; bone volum
A single exercise bout augments adenovirus-specific T-cell mobilization and function
Keywords: Allogeneic hematopoietic stem cell transplantation; Adoptive transfer immunotherapy; ex vivo expansion; Viral infections; Exercise immunology; Acute stress response; AdV; adenovirus; alloHSCT; allogeneic hematopoietic stem cell transplantation; β2AR; β2
Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase
Keywords: ARRB; β-arrestin; β2AR; β2-adrenergic receptor; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; LOF; loss-of-function; αMSH; α melanocyte-stimulating hormone; MCR; melanocortin receptor; MC1R; melanocortin 1 receptor; MGRN1;
Targeting central β2 receptors ameliorates streptozotocin-induced neuroinflammation via inhibition of glycogen synthase kinase3 pathway in mice
Keywords: Aβ; amyloid β protein; AD; Alzheimer's disease; β2AR; β2 adrenoceptor; FAD; familial AD; F; formoterol; GSH; reduced glutathione; GSK-3; glycogen synthase kinase-3; GSK α and β; glycogen synthase kinase alpha and beta; H&E; hematoxylin &eosin; Iba1;
The G protein-coupled receptors deorphanization landscape
Keywords: GPCRs; G protein-coupled receptors; GRK; GPCR kinase; IUPHAR; International Union of Basic and Clinical Pharmacology; BPS; British Pharmacological Society; CTR; Calcitonin receptor; CLR; CT Receptor-like; RAMP; Receptor Activity-Modifying Proteins; β2AR;
ReviewConcerns with beta2-agonists in pediatric asthma - a clinical perspective
Keywords: β2-agonists; Tolerance; Asthma; Genetic polymorphisms; cAMP; cyclic adenosine monophosphate; BARGE; Beta Adrenergic Response by Genotype; β2AR; β2-adrenoreceptor; BHR; bronchial hyperresponsiveness; EIB; exercise induced bronchoconstriction; FDA; food
Reciprocal regulation of β2-adrenoceptor-activated cAMP response-element binding protein signalling by arrestin2 and arrestin3
Keywords: ATF-1; activation of transcription factor-1; β1AR; β1 adrenoceptor; β2AR; β2 adrenoceptor; CGP-20712A; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride; CREB; cAMP respo
Effects of β-blockers on house dust mite-driven murine models pre- and post-development of an asthma phenotype
Keywords: β-adrenoceptor blockers; House dust mite; Murine model; Asthma; Extracellular-signal regulated kinases 1/2; AHR; airway hyperresponsiveness; β2AR; β2-adrenoceptor; BALF; bronchoalveolar lavage fluid; cAMP; cyclic adenosine monophosphate; ERK1/2; extrac
Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization
Keywords: GPCR; Heterodimerization; Arrestin; BRET; Biased signaling; G protein-coupled receptors; GPCR; Angiotensin type 1A receptor; AT1R; β2-adrenergic receptors; β2AR; serotonin 2C receptor; 5HT2CR; angiotensin II; AngII; Isoproterenol; ISO; Renilla luciferas
Novel signaling of dynorphin at κ-opioid receptor/bradykinin B2 receptor heterodimers
Keywords: AC; adenylyl cyclase; B1R; bradykinin B1 receptor; B2R; bradykinin B2 receptor; BK; bradykinin; BRET; bioluminescence resonance energy transfer; CFP; cyan fluorescent protein; CNS; central nervous system; CRE; cAMP-response element; CREB; cAMP-response el
Structure and Function of Peptide-Binding G Protein-Coupled Receptors
Keywords: AM1, AM2; adrenomedullin receptors; AMY1, AMY2, AMY3; amylin receptors; AT1, AT2; angiotensin receptors; APLNR; apelin receptor; RFamide; arginine-phenylalanine-amide; β2AR; β2-adrenergic receptor; BB1, BB2, BB3; bombesin receptors; B1, B2; bradykin
An aromatic amino acid within intracellular loop 2 of the prostaglandin EP2 receptor is a prerequisite for selective association and activation of Gαs
Keywords: β2AR; β2 adrenergic receptor; CHO; Chinese hamster ovary; EDTA; ethylenediaminetetraacetic acid; GPCR; G protein-coupled receptor; ICL1-4; intracellular loops 1 to 4 of G protein-coupled receptors; PGE2; prostaglandin E2; SPR; surface plasmon resonance;
The yeast Ste2p G protein-coupled receptor dimerizes on the cell plasma membrane
Keywords: BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; C-EGFP; C-terminal domain of enhanced green protein; EGFP; enhanced green fluorescent protein; ER; endoplasmic reticulum; FRET; Förster resonance energy tran
Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells
Keywords: AC; adenylyl cyclase; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; β2AR; β2-adrenergic receptor; CBR; cannabinoid receptor; ICI-118,551; (erythro-DL-1(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-o
α-Hederin inhibits G protein-coupled receptor kinase 2-mediated phosphorylation of β2-adrenergic receptors
Keywords: β2-adrenergic receptor; GRK2; phosphorylation; homologous desensitization; α-hederin; β2AR; β2-adrenergic receptor; PKA; protein kinase A; GRK2; G protein-coupled receptor kinase 2; GFP; green fluorescent protein; FRET; Förster resonance energy trans
Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins
Keywords: GPCR; β-arrestin; KLHL12; ubiquitination; dopamine D4 receptor; β2AR; β2-adrenergic receptor; ADHD; attention deficit hyperactivity disorder; BTB; bric à brac 1, tramtrack, and broad-complex; co-IP; co-immunoprecipitation; CXCR4; C-X-C chemokine recep
FRET biosensors reveal AKAP-mediated shaping of subcellular PKA activity and a novel mode of Ca2Â +/PKA crosstalk
Keywords: AKAP; A-Kinase Anchoring Protein; AKAR3; A-Kinase activity reporter 3; β2AR; β2-adrenergic receptor; [Ca2 +]i; intracellular calcium concentration; CaM; calcium-calmodulin; cAMP; cyclic adenosine monophosphate; CB4; calmodulin binding domain 4; CFP; cy
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
Keywords: ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5â²AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long
The epicardium as modulator of the cardiac autonomic response during early development
Keywords: β1AR; β1 adrenergic receptor; β2AR; β2 adrenergic receptor; cANS; cardiac autonomic nervous system; CTNI; cardiac Troponin I; E; embryonic day; EMT; epithelial-to-mesenchymal transition; HH; Hamburger and Hamilton; NCAM; Neural Cell Adhesion Molecule;
PDZK1/NHERF3 Differentially Regulates Corticotropin-releasing Factor Receptor 1 and Serotonin 2A Receptor Signaling and Endocytosis
Keywords: ANOVA; analysis of variance; β 1AR; β 1-adrenergic receptor; β2AR; β2-adrenergic receptor; CRF; corticotropin-releasing factor; CRFR1; CRF receptor 1; CRFR2; CRF receptor 2; ERK1/2; extracellular signal-regulated kinase; GKAP; guanylate kinase-associa
IL-13 desensitizes β2-adrenergic receptors in human airway epithelial cells through a 15-lipoxygenase/G protein receptor kinase 2 mechanism
Keywords: IL-13; cAMP; phosphatidylethanolamine binding protein 1; 15-lipoxygenase 1; β2-adrenergic receptor; G protein receptor kinase 2; asthma; ALI; Air-liquid interface; ALOX15; Arachidonate 15-lipoxygenase; β2AR; β2-Adrenergic receptor; cAMP; Cyclic adenosi
Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: Biochemical and electrophysiological characterization
Keywords: RO5328673; Dual NK2/NK3 antagonist; Inositol phosphate accumulation; Firing frequency; Locomotor activity; NK3 modeling; SP; substance P; NKA; neurokinin A; NKB; neurokinin B; GPCRs; G-protein coupled receptors; IP; inositol phosphates; DA; dopamine; NA;
CHIP-MYTH: A novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β2-adrenergic receptor
Keywords: membrane two-hybrid assay; protein-protein interactions; G-protein coupled receptors; drug-dependent protein interactions; high-throughput screening; LUMIER assay; Ade; adenine; 3-AT; 3-amino-1,2,4-triazole; β2AR; beta2-adrenergic receptor; Cub; carboxy-
Receptor-mediated Ca2Â + and PKC signaling triggers the loss of cortical PKA compartmentalization through the redistribution of gravin
Keywords: AKAP; A-Kinase Anchoring Protein; ATP; adenosine triphosphate; β2AR; β2-adrenergic receptor; BAPTA-AM; 1,2-Bis(2-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid tetrakis(acetoxymethyl ester); BIM; bisindolylmaleimide; [Ca2 +]i; intracellular calcium
Evidence for genetic linkage between a polymorphism in the GNAS gene and malaria in South Indian population
Keywords: Gαs; G-alpha subunit; SNP; single nucleotide polymorphism; β2AR; beta 2 adrenoreceptor; GPCR; G-protein coupled receptor; PVM; parasitophorous vacuole membrane; cAMP; cyclic adenosine monophosphate; RFLP; restriction fragment length polymorphism; CNV; c
Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit
Keywords: GRPR; gastrin-releasing peptide receptor; BK2R; bradykinin type 2 receptor; β2AR; β2 adrenergic receptor; MT1R; melatonin type 1 receptor; CHX; cycloheximide; eIF; eukaryotic initiation factor; 4EBP1; eIF4E binding protein 1; RGS; regulator of G protein
Functional interactions between the oxytocin receptor and the β2-adrenergic receptor: Implications for ERK1/2 activation in human myometrial cells
Keywords: AC; adenylyl cyclase; β2AR; β2-adrenergic receptor; cAMP; cyclic adenosine monophosphate; CFP; cyanide fluorescent protein; CYP; cyanopindolol; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulphoxide; DNA; deoxyribonucleic acid; EGF; epitheli
Fluorescence ratiometric detection of ligand-induced receptor internalization using extracellular coiled-coil tag-probe labeling
Keywords: Endocytosis; Tag-probe labeling; Ratio imaging; Membrane receptor; High-throughput screening; β2AR; the human β2-adrenergic receptor; CHO; Chinese hamster ovary; E3; (EIAALKE)3; E3-β2AR; the E3-tagged human β2 adrenergic receptor; FL; fluorescein; K
A common variant in the β2-adrenergic receptor and risk of sudden cardiac death
Keywords: Beta2-adrenergic receptor; Genetic epidemiology; Sudden cardiac death; Sympathetic nervous system; ADRB2; β2-adrenergic receptor gene; β1AR; β1-adrenergic receptor; β2AR; β2-adrenergic receptor; CABS; Cardiac Arrest Blood Study; CAD; coronary artery
Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas)
Keywords: Beta adrenergic receptor; β1AR; β2AR; β3AR; Fathead minnow; Pimephales promelas; G protein-coupled receptor; Gene expression; Propranolol exposure;
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles
Keywords: DPH; 1,6-diphenyl-1,3,5-hexatriene; Compound-24; 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),40-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide; β1AR; β1-adrenergic receptor; β2AR; β2-adrenergic receptor; CCM; cholesterol consensus motif; CHS; cholestery
Solution- and solid-state NMR studies of GPCRs and their ligands
Keywords: β2AR; β2 adrenergic receptor; CP; cross polarisation; CXCR1; chemokine receptor; DAGK; diacylglycerol kinase; GPCR; G protein-coupled receptor; MAS; magic angle spinning; MBP; maltose binding protein; NOE; nuclear overhauser effect; NTS1; neurotensin re
Long and short distance movements of β2-adrenoceptor in cell membrane assessed by photoconvertible fluorescent protein dendra2-β2-adrenoceptor fusion
Keywords: β2AR; β2-adrenoceptor; FRAP; fluorescence recovery after photobleaching; GFP; green fluorescent protein; GPCR; G protein-coupled receptor; FCS; fluorescence correlation spectroscopy; SPT; single particle (or fluorescent molecule) tracking; β-adrenocept
Interactive effects of steroids and β-agonists on accumulation of type 2 T cells
Keywords: Human; T cells; β-adrenergic receptor; β-agonist; asthma; IL-13; glucocorticosteroid; steroid; IL-2; β2AR; β2-Adrenergic receptor; GM; Geometric mean; Kd; Dissociation constant; LABA; Long-acting β-agonist; PBL; Peripheral blood lymphocyte; SABA; Sho
Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners
Keywords: Cystic fibrosis transmembrane conductance regulator; Macromolecular complex; PDZ protein; Interacting partner; ABC; ATP-binding cassette; AFM; atomic force microscopy; AKAP; A-kinase anchoring protein; AMPK; AMP-activated kinase; AP-2; adaptor protein com