کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10081815 | 1604096 | 2005 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Metal-on-Metal Total Hip Replacement
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
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چکیده انگلیسی
Second-generation metal-on-metal (M/M) total hip replacements were introduced into clinical use in the late 1980s and demonstrate equivalent survivorship to conventional metal-on-polyethylene prostheses. Wear rates are comparable to those of first-generation designs that survived for a long time in the body. Biological effects from metal ions remain a concern. Patients with both first- and second-generation M/M hips have higher levels of cobalt and chromium in their blood and urine than either patients with metal-on-polyethylene devices or unoperated patients. Concerns include the potential for acquired hypersensitivity, mutagenicity, and carcinogenicity. However, reports of proven adverse effects are scant. Prospective, randomized trials with follow-up in excess of 15 years will be needed to differentiate between the performance and effects of M/M and other bearing combinations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 20, Issue 2, February 2005, Pages 174-188
Journal: The Journal of Arthroplasty - Volume 20, Issue 2, February 2005, Pages 174-188
نویسندگان
John H. PhD, DSc, Michael T. PhD,