کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10103906 1612354 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ductal carcinoma in situ of the breast and heparanase-1 expression: A molecular explanation for more aggressive subtypes
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Ductal carcinoma in situ of the breast and heparanase-1 expression: A molecular explanation for more aggressive subtypes
چکیده انگلیسی
HPR1 was expressed at a significantly higher frequency in the invasive comedo and DCIS with microinvasion subtypes than in the noninvasive subtypes. HPR1 expression was inversely associated with HS deposition in the extracellular basement membrane of the DCIS. HPR1 expression was associated with a higher VNPI score. These observations suggest that HPR1 expression in DCIS can play an important role in development of DCIS into an invasive breast cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Surgeons - Volume 200, Issue 3, March 2005, Pages 328-335
نویسندگان
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