کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10129149 | 1645202 | 2018 | 32 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and characterization of schizophyllan nanogels via inverse emulsion using biobased materials
ترجمه فارسی عنوان
سنتز و مشخص کردن نانو ذرات اسکیزوفیلن با استفاده از امولسیون معکوس با استفاده از مواد بیولوژیکی
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کلمات کلیدی
اسکیزوفیلان، نانوگل، امولسیون معکوس، روغن نارگیل منیزیم، ساکارز اکسید شده،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
Oxidized sucrose cross-linked Schizophyllan nanogel was successfully synthesized via inverse emulsion method for the first time. The synthesis process was conducted in the absence of both toxic cross-linker and organic solvent. The nanogel crosslinking network was prepared using fractionated coconut oil as the continuous phase and oxidized sucrose as the cross-linker. The formation of ether linkage on schizophyllan cross-linked structure was confirmed by Fourier transform infrared microscopy (FTIR) analysis. Size and morphology were evaluated by DLS analysis and SEM. The results showed that increasing the concentration of surfactant causes the decrease in the size. By keeping surfactant amounts constant, the increase in the amount of crosslinker caused increase in the size and swelling degree. Nontoxicity of the nanogels was proved by in vitro MTT analysis. The obtained nanogels, possess special properties such as high water content, colloidal stability, bioactivity, functionality, and interior network for drug loading capacity offer great potential for the utilization of nanogels in biomedical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 120, Part A, December 2018, Pages 468-474
Journal: International Journal of Biological Macromolecules - Volume 120, Part A, December 2018, Pages 468-474
نویسندگان
Sahar Mousaviasl, Tayebeh Saleh, Seyed Abbas Shojaosadati, Soheil Boddohi,