A novel bubble-forming material for preparing hydrophobic-agent-loaded bubbles with theranostic functionality

A new bubble-forming material (CHC) together with SPIO nanoparticles was empolyed to prepare MR image-guided nanobubbles for efficiently encapsulating hydrophobic drug (CPT), and exerting US-triggered toxicity which was ascribed to the synergistic effect of CHC and US bombardment on transmembrane delivery.81