Effects of simultaneous internal and external mass transfer and product inhibition on immobilized enzyme-catalyzed reactor

The effects of simultaneous internal and external mass transfer coupled with product inhibition have been studied and their effects were shown to reduce internal effectiveness factor. The effects of product inhibition have been investigated at different operating conditions correlated at different regimes using dimensionless βxo (St, Bi, θ, ϕ). Product inhibition was shown to reduce substrate conversion, and to decrease effectiveness factor when βs > βxo; however, it increases internal effectiveness factor when βs < βxo. The effectiveness factor is found to be independent of product inhibition at crossover point at which βxo is defined. Effects of St and Bi have been investigated at different kinetic regimes and the results show their effects have a strong dependence on kinetic parameters θ, γ (i.e. Km/Kp) and βxo. The dimensionless residence time at crossover point, βxo, has been correlated with kinetic and mass transfer parameters.