کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10275718 | 463387 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electrochemical activity of new ferrocene-labelled PNA monomers to be applied for DNA detection: Effects of the molecular structure and of the solvent
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
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چکیده انگلیسی
PNA oligomers are promising candidates as DNA probes on account of their very high DNA binding power, but they generally require an appropriate electrochemically or spectroscopically active marker. This paper describes the systematic electrochemical characterization of two newly synthesized PNA monomers, derivatised with one or three active ferrocene groups, and of their precursors. Our monomers show high electrochemical activity in spite of their bulkiness; moreover, the systematicity of our investigation affords an interesting analysis of the role of the molecular structure, the degree of functionalization and the working solvent on the electrochemical activity of the organometallic site.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electroanalytical Chemistry - Volume 585, Issue 2, 15 November 2005, Pages 197-205
Journal: Journal of Electroanalytical Chemistry - Volume 585, Issue 2, 15 November 2005, Pages 197-205
نویسندگان
Clara Baldoli, Emanuela Licandro, Stefano Maiorana, Dario Resemini, Clara Rigamonti, Luigi Falciola, Mariangela Longhi, Patrizia Romana Mussini,