کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10303825 | 545625 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Combined treatment of borderline personality disorder with interpersonal psychotherapy and pharmacotherapy: Predictors of response
ترجمه فارسی عنوان
درمان ترکیبی اختلال شخصیت مرزی با روان درمانگری بین فردی و دارویی: پیش بینی کننده پاسخ
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کلمات کلیدی
روان درمانی بین فردی، فلوکستین، درمان ترکیبی اختلال شخصیت مرزی، نتیجه پیش بینی کنندگان،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Borderline personality disorder (BPD) is characterized by affective instability, impulsive behaviors, and disturbed interpersonal relationships. A previous study of our group found that combined therapy with interpersonal psychotherapy adapted to BPD (IPT-BPD) and fluoxetine was superior to single pharmacotherapy in BPD patients. The aim of the present study was to examine what clinical factors predicted response to combined therapy in patients evaluated in the previous efficacy study. The subgroup of 27 patients allocated to combined therapy was analyzed. Patients were treated for 32 weeks with fluoxetine 20-40Â mg/day plus IPT-BPD. Patients were assessed at baseline and week 32 with an interview for demographic and clinical variables, CGI-S, HDRS, HARS, SOFAS, BPDSI, and SAT-P. Statistical analysis was performed with multiple regression. The difference of CGI-S score between baseline and week 32 (âCGI-S) was the dependent variable. Factors significantly and independently related to âCGI-S were the BPDSI total score and the items abandonment, affective instability, and identity. Patients with more severe BPD psychopathology and with a higher degree of core symptoms such as fear of abandonment, affective instability, and identity disturbance have a better chance to improve with combined therapy with fluoxetine and IPT-BPD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 226, Issue 1, 30 March 2015, Pages 284-288
Journal: Psychiatry Research - Volume 226, Issue 1, 30 March 2015, Pages 284-288
نویسندگان
Silvio Bellino, Paola Bozzatello, Filippo Bogetto,