کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10305797 | 547030 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diurnal profiles of salivary cortisol and alpha-amylase change across the adult lifespan: Evidence from repeated daily life assessments
ترجمه فارسی عنوان
پروفایل روزانه کورتیزول بزاق و آلفا آمیلاز در طول عمر بالغ تغییر می کند: شواهد از ارزیابی های روزانه زندگی تکراری
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کلمات کلیدی
سالخورده، کورتیزول، طول عمر، آلفا آمیلاز بزاق،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
Salivary cortisol and alpha-amylase are known to have distinctive diurnal profiles. However, little is known about systematic changes in these biomarkers across the adult lifespan. In a study of 185 participants (aged 20-81 years), time-stamped salivary cortisol and alpha-amylase were collected 7 times/day over 10 days. Samples were taken upon waking, 30Â min later, and then approximately every 3Â h until 9Â pm. Multilevel models showed that older age was associated with increased daily cortisol secretion as indicated by greater area under the curve, attenuated wake-evening slopes, and more pronounced cortisol awakening responses. Further, older age was related to greater daily alpha-amylase output and attenuated wake-evening slopes. No age differences were observed regarding the alpha-amylase awakening response. Our findings may contribute to a better understanding of age-related differences in functioning of stress-related systems.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychoneuroendocrinology - Volume 38, Issue 12, December 2013, Pages 3167-3171
Journal: Psychoneuroendocrinology - Volume 38, Issue 12, December 2013, Pages 3167-3171
نویسندگان
Urs M. Nater, Christiane A. Hoppmann, Stacey B. Scott,