کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10306019 | 547104 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The relation of salivary cortisol to patterns of performance on a word list learning task in healthy older adults
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
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چکیده انگلیسی
A pattern of performance on a word list learning task known as a reduced primacy effect has been shown to be characteristic of Alzheimer's disease (AD) and can distinguish AD from depression. Deficits in memory and hippocampal atrophy seen in AD have been associated with hypercortisolism. The present study evaluated whether the reduced primacy effect is associated with elevated salivary cortisol in a sample of 40 healthy older community-dwelling adults participating in a study of memory and stress. We found that primacy, but not recency, was associated with higher salivary cortisol levels. In addition, participants who showed a reduced primacy had higher salivary cortisol levels than those with a normal serial position curve. Results suggest that there may be value to examining both serial position curves and changes to cortisol patterns over time as potential predictors of cognitive decline in healthy older adults.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychoneuroendocrinology - Volume 33, Issue 9, October 2008, Pages 1293-1296
Journal: Psychoneuroendocrinology - Volume 33, Issue 9, October 2008, Pages 1293-1296
نویسندگان
Julie Suhr, Petya Demireva, Kathi Heffner,